Seymour J. Klebanoff

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University of Washington
School of Medicine
Medicine
Allergy and Infectious Diseases
ProfessorAppointed: 1969

Mailing Address

Box 357185
University of Washington
Seattle, Washington 98195
United States

Contact Information

Phone: (206) 543-7902
Fax: (206) 685-8681
seym@u.washington.edu

Qualifications

Ph.D., Uk-U London Fac Med, 1954.
M.D., Uk-U London Fac Med, Med, 1951.

Keywords

COS Keywords:

Allergy.

Additional Terms:

Allergy, Cancer/tumor Biology/oncology: Growth Factors/cytokinesis, Cancer/tumor Biology/oncology: Training, Cell Biology: Cell Kinetics/mitosis/stem Cells, Clinical Trials/drug Studies, Growth Factors/growth Factor Receptors, Immunology/immunobiology: Inflammation, Immunology/immunobiology: Inflammation: Neutrophils, Infectious Diseases, Reproductive Biology: Female: Disease.

Previous Positions

Associate Chair, 1997-present

Publications

  • Mehlin C, Headley CM, Klebanoff SJ, An inflammatory polypeptide complex from Staphylococcus epidermidis: isolation and characterization., Journal of Experimental Medicine, 189(6), 907-18, 15 Mar 1999 Abstract
  • Klebanoff SJ, Watts DH, Mehlin C, Headley CM, Lactobacilli and vaginal host defense: activation of the human immunodeficiency virus type 1 long terminal repeat, cytokine production, and NF-kappaB., Journal of Infectious Diseases, 179(3), 653-60, March 1999 Abstract
  • Klebanoff SJ, Headley CM, Activation of the human immunodeficiency virus-1 long terminal repeat by respiratory burst oxidants of neutrophils., Blood, 93(1), 350-6, 1 Jan 1999 Abstract
  • Klebanoff S J, Mehlin C, Headley C M, Activation of the HIV type 1 long terminal repeat and viral replication by dimethylsulfoxide and related solvents., Aids Research and Human Retroviruses, 13(14), 1221-7, 20 Sep 1997 Abstract
  • Kiener P A, Davis P M, Rankin B M, Klebanoff S J, Ledbetter J A, Starling G C, Liles W C, Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation., Journal of Immunology, 159(4), 1594-8, 15 Aug 1997 Abstract
  • Kiener P A, Davis P M, Starling G C, Mehlin C, Klebanoff S J, Ledbetter J A, Liles W C, Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages., Journal of Experimental Medicine, 185(8), 1511-6, 21 Apr 1997 Abstract
  • Liles W C, Kiener P A, Ledbetter J A, Aruffo A, Klebanoff S J, Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils., Journal of Experimental Medicine, 184(2), 429-40, 1 Aug 1996 Abstract
  • Klebanoff S J, Coombs R W, Virucidal effect of stimulated eosinophils on human immunodeficiency virus type 1., Aids Research and Human Retroviruses, 12(1), 25-9, 1 Jan 1996 Abstract
  • Kazazi F, Koehler J K, Klebanoff S J, Activation of the HIV long terminal repeat and viral production by H2O2-vanadate., Free Radical Biology and Medicine, 20(6), 813-20, 1996 Abstract
  • Liles W C, Ledbetter J A, Waltersdorph A W, Klebanoff S J, Cross-linking of CD18 primes human neutrophils for activation of the respiratory burst in response to specific stimuli: implications for adhesion-dependent physiological responses in neutrophils., Journal of Leukocyte Biology, 58(6), 690-7, December 1995 Abstract
  • Liles W C, Dale D C, Klebanoff S J, Glucocorticoids inhibit apoptosis of human neutrophils., Blood, 86(8), 3181-8, 15 Oct 1995 Abstract
  • Liles W C, Klebanoff S J, Regulation of apoptosis in neutrophils--Fas track to death?, Journal of Immunology, 155(7), 3289-91, 1 Oct 1995 Abstract
  • Liles W C, Ledbetter J A, Waltersdorph A W, Klebanoff S J, Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes., Journal of Immunology, 155(4), 2175-84, 15 Aug 1995 Abstract
  • Klebanoff S J, Kazazi F, Inactivation of human immunodeficiency virus type 1 by the amine oxidase-peroxidase system., Journal of Clinical Microbiology, 33(8), 2054-7, August 1995 Abstract
  • Klebanoff S J, Kazazi F, Van Voorhis W C, Schlechte K G, Activation of the human immunodeficiency virus long terminal repeat in THP-1 cells by a staphylococcal extracellular product., Proceedings of the National Academy of Sciences (USA), 91(22), 10615-9, 25 Oct 1994 Abstract
  • Klebanoff S J, Nathan C F, Nitrite production by stimulated human polymorphonuclear leukocytes supplemented with azide and catalase., Biochemical and Biophysical Research Communications, 197(1), 192-6, 30 Nov 1993 Abstract
  • Klebanoff S J, Kinsella M G, Wight T N, Degradation of endothelial cell matrix heparan sulfate proteoglycan by elastase and the myeloperoxidase-H2O2-chloride system., American Journal of Pathology, 143(3), 907-17, September 1993 Abstract
  • Hillier S L, Krohn M A, Rabe L K, Klebanoff S J, Eschenbach D A, The normal vaginal flora, H2O2-producing lactobacilli, and bacterial vaginosis in pregnant women., Clinical Infectious Diseases, 16 Suppl 4, S273-81, June 1993 Abstract
  • Klebanoff S J, Schlechte K G, Waltersdorph A M, Stimulation of the bactericidal activity of polymorphonuclear leukocytes by manganese., Journal of Leukocyte Biology, 53(6), 666-72, June 1993 Abstract
  • Klebanoff S J, Reactive nitrogen intermediates and antimicrobial activity: role of nitrite., Free Radical Biology and Medicine, 14(4), 351-60, April 1993 Abstract
  • Klebanoff S J, Olszowski S, Van Voorhis W C, Ledbetter J A, Waltersdorph A M, Schlechte K G, Effects of gamma-interferon on human neutrophils: protection from deterioration on storage., Blood, 80(1), 225-34, 1 Jul 1992 Abstract
  • Chase M J, Klebanoff S J, Viricidal effect of stimulated human mononuclear phagocytes on human immunodeficiency virus type 1., Proceedings of the National Academy of Sciences (USA), 89(12), 5582-5, 15 Jun 1992 Abstract
  • Klebanoff S J, Bactericidal effect of Fe2+, ceruloplasmin, and phosphate., Archives of Biochemistry and Biophysics, 295(2), 302-8, June 1992 Abstract
  • Klebanoff S J, Coombs R W, Viricidal effect of polymorphonuclear leukocytes on human immunodeficiency virus-1. Role of the myeloperoxidase system., Journal of Clinical Investigation, 89(6), 2014-7, June 1992 Abstract
  • Hillier S L, Krohn M A, Klebanoff S J, Eschenbach D A, The relationship of hydrogen peroxide-producing lactobacilli to bacterial vaginosis and genital microflora in pregnant women., Obstetrics and Gynecology, 79(3), 369-73, March 1992 Abstract
  • Klebanoff S J, Effects of the spermicidal agent nonoxynol-9 on vaginal microbial flora [see comments], Journal of Infectious Diseases, 165(1), 19-25, January 1992 Abstract
  • Klebanoff S J, Hillier S L, Eschenbach D A, Waltersdorph A M, Control of the microbial flora of the vagina by H2O2-generating lactobacilli., Journal of Infectious Diseases, 164(1), 94-100, July 1991 Abstract
  • Klebanoff S J, Coombs R W, Viricidal effect of Lactobacillus acidophilus on human immunodeficiency virus type 1: possible role in heterosexual transmission., Journal of Experimental Medicine, 174(1), 289-92, 1 Jul 1991 Abstract
  • Klebanoff S J, Waltersdorph A M, Prooxidant activity of transferrin and lactoferrin., Journal of Experimental Medicine, 172(5), 1293-303, 1 Nov 1990 Abstract
  • Klebanoff S J, Waltersdorph A M, Michel B R, Rosen H, Oxygen-based free radical generation by ferrous ions and deferoxamine., Journal of Biological Chemistry, 264(33), 19765-71, 25 Nov 1989 Abstract

Profile Details

Last Verified: 6/13/2007

COS Expertise ID #135097
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