King's College London King's College London Dental Institute Periodontology Honorary ConsultantAppointed: 1997 |  |
QualificationsFellow Higher Education Acad, King's College London Dental Institute at GKT Hospitals, Periodontology, 2007. Ph.D., University of London, 1989. F.D.S., Royal College of Surgeons of England, 1978. B.D.S., Dental Surgery, 1975. Expertise and Research InterestsFull time clinical academic specialist in Periodontology for undergraduates and postgraduates.
Clinical Lead Periodontology, King's College Dental Hospital Trust Chair Diploma in Dental Hygiene and Therapy Examination. Member External Development Committee KCL Dental Institute at Guy's King's & St.Thomas' Hospitals Member working party for Academic strategy Development King's College Dental Hospital Clinical Dental Trust Lead, Infection Control Committee King's College Hospital Chair, King's College Dental Hospital Infection Control Committee Clinical & research interests: Comprehensive management of periodontal patients, using chemical adjuncts / biomaterials as indicated for surgical interventions. Risk markers of oxidative stress in periodontal and systemic diseases, therapeutic intervention.
Post-graduate and post-doctoral periodontal programmes on the above theme have resulted in presentations at national and international clinical and scientific fora and publications in peer reviewed journals.
Awards (1993-to date), won by post-graduates working in this field: Dentsply student clinician award (1993-1994), also presented at a research forum in New Orleans, USA. Procter & Gamble, Oral and Dental Research Trust awards (1993-1996). Royal Society of Medicine, London: Invited presentations on the above themes (1993-96). Undergraduate Periodontal Essay prize, awarded by the British Society of Periodontology (1994). Sir Wilfred Fish prize entry, certificate of merit for presentation on steroid conversions in Treponema denticola, awarded by the British Society of Periodontology (Sept 1993). European Federation of Periodontology, Florence, Italy (1997). Invited presentation on modifying factors for wound healing in an in vitro model George Cross Fellowship 2002-2003, awarded by the British Society of Periodontology.
Editorial work for journals: Journal of Endocrinology, Journal of Dental Research, Archives of Oral Biology, Biomacromolecules, Journal of Dermatological Science, Oral Diseases, Biochemical Journal, European Journal of Oral Science, Epilepsia, Analytical Chemistry Insights, Journal of Oral Pathology and Medicine, Biomed Central, Open Dentistry Journal, Journal of Dentistry, British Dental Journal and the International Dental Journal.
Member, Editorial Boards of 3 international journals
Co-author, 2 Periodontal books
Review grant applications for: Medical Research Council, Wellcome Trust, Irish Health Research Board and the Rayne Institute, University of Western Australia.
Inclusion in 3 International Expert Directories, based on clinical & research themes described above.
Invited Consultancies with Oral Health Consortia and Industry Other ExpertiseInitiation and development: Established collaborative links for research and teaching with universities in the U.K. and overseas Future Research1. Biomarkers of wound healing in response to biomaterials / antioxidants 2. Periodontal disease in systemically ill patient Industrial RelevanceAim: To establish a risk factor index for periodontal patients KeywordsCOS Keywords:Cell Culture, Connective Tissue, Curriculum Development, Dental Health and Hygiene, Dentistry, Endocrinologic Diseases, Endocrinology, Gas Chromatography.Additional Terms:Antioxidants in Periodontal, Biomaterials in Periodontal Diseases, Metabolic Diseases, Non-antimicrobial actions of Tetracyclines, Repair Potential in Periodontal Diseases, Steroid Hormones as Biomarkers of oxidative stress.Languages(Reading, Writing, Speaking)English: (Fluent, Fluent, Fluent) MembershipsAcademy of Dental Implantology British Dental Association British Society for Dental Research British Society of Periodontology Endocrine Society Higher Education Academy International Academy of Periodontology International Association for Dental Research Honors and Awards2007, Fellow,
Higher Education Academy, UK
1977-1978,
Leverhulme Fellowship,
Leverhulme Foundation,
Institute of Dental Surgery EDH,
Dentistry
Previous Positions1981-1997, Clinical Lecturer, Senior Clinical Lecturer, Honorary Consultant,
King's College School of Medicine and Dentistry
1980-1981, Registrar (Restorative Dentistry),
University College Hospital
1979-1980, Resident Senior House Officer,
Barnet General Hospital
1977-1978, Leverhulme Fellow,
Institute of Dental Surgery,
Eastman Dental Hospital
Funding Received- Procter & Gamble Oral & Dental Research Trust:
Steroidogenesis in periodontopathic bacteria and in gingival fibroblasts in response to therapeutic agents,
£3,500,
May 1994
to 1995.
- Procter & Gamble Oral and Dental Research Trust:
An investigation of steroidogenesis by a) Periodontopathic bacteria and b) Human gingival fibroblasts: effects of growth factors and drugs on this conversion.,
£4,304,
May 1993
to May 1994.
- KCL, Dental Research Committee, Range lll application:
The influence of cytokines and growth factors on the repair potential of gingival and periodontal ligament fibroblasts with regard to C19 steroid conversions,
£1,200,
Jan 1992
to Jan 1993.
- Egyptian Government Scholarship, Channel Link PhD Programme:
Effect of lasers on bone regeneration in periodontal bone defects in the presence or absence of bioglass,
2005
to 2007.
- University of Madrid, Spain: Two centre PhD programme:
Oxidant / antioxidant interactions of nicotine, Coenzyme Q10, Pycnogenol and phytoestrogens in a cell culture model,
2005
to 2005.
- George Cross Fellowship:
The role of anti-oxidants on nicotine mediated effects in gingival and oral periosteal fibroblasts,
£2,996. 86,
2002
to 2003.
- Procter & Gamble Oral and Dental Research Trust:
Influence of growth factors and therapeutic agents on steroid hormone biomarkers of healing in fibroblasts.,
£4,500,
1996
to 1997.
- Procter & Gamble Oral and Dental Research Trust:
Effects of steroid hormones, bacterial products and therapeutic agents on gingival and periosteal fibroblasts,
£3,000,
1995
to 1996.
- Equipment Committee, for an IBM upgrade for the Berthold Linear Analyser (radioisotope scanner).:
Steroid biomarkers for growth factor mediated responses in the periodontium & steroidogenesis in Treponema denticola with relevance to survival in the host.,
£4,500,
1995
to to date.
- KCL, Equipment Committee, for a Howe Gyrovap sample concentrator:
Cytokine and growth factor regulation of repair in the periodontium and b) steroidogenesis by Treponema denticola, implications on survival and host defences,
£4,865,
1993
to to date.
- Intercalated B.Sc. project:
The metabolism of C19 steroids by gingival fibroblasts in response to inflammatory mediators,
£ 500,
1992
to 1993.
- King's College London:
The conversion of C19 steroids by human gingival and periodontal ligament fibroblasts in response to inflammatory mediators,
£30,000,
1991
to 1994.
Publications- Soory, M (2009) Periodontal diseases and rheumatoid arthritis: Coincident mechanisms of disease progression, British Society for Dental Research, Oral Microbiology and Immunology Symposium (Abstract)
- A. Tilakaratne, M.Soory (2009) Acute phase reactants and response to doxycycline in cultured osteoblasts, Journal of Dental Research (Abstract), In Press
- Soory, M (2009) Relevance of dyslipidaemia and its consequences in periodontal patients with co-existing cardiovascular disease and diabetes mellitus: Therapeutic targets., Recent Patents on Endocrine Metabolic and Immune Drug Discovery, In Press
- Soory, M (2009) Redox status in periodontal and systemic inflammatory conditions including associated neoplasias: Antioxidants as adjunctive therapy?, Infectious Disorders - Drug Targets (Supplement on Redox status in the pathophysiology of inflammation and therapeutic targets), 9, 415-27
- Soory, M (2009) Relevance of nutritional antioxidants in metabolic syndrome, ageing and cancer: potential for therapeutic targeting, Infectious Disorders-Drug Targets (Supplement on Redox status in the pathophysiology of inflammation and therapeutic targets), 9, 400-14
- AboElsaad, N.S, Soory, M, Gadalla, L.M, Ragab, L.I, Dunne, S, Zalata, K.R, Louca, C (2009) Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (An experimental study), Lasers in Medical Science, 24, 527-533
- AboElsaad, N.S, Soory, M, Gadalla, L.M, Ragab, L.I, Dunne, S, Zalata, K.R, Louca, C (2009) Effect of soft laser and bioactive glass on bone regeneration in the treatment of infrabony defects (A clinical study), Lasers in Medical Science, 24, 387-395
- Soory, M (2008) Periodontal regenerative materials and their applications: Goodness of fit?, Recent Patents on Endocrine Metabolic and Immune Drug Discovery, 2, 35-44
- Soory, M (2008) A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases, The Open Dentistry Journal, 2, 5-12
- Soory, M (2008) Oxidative stress in periodontal diseases and associated neoplasias: a role for antioxidants?, World Ehrlich Congress on anti-neoplastics, World Conference on Magic Bullets, Abstract pages, In Press
- Soory M, Tilakaratne (2008) Anabolic response of osteoblasts to doxycycline in an inflammatory model, Pan European Federation Meeting, London, UK, International Association for Dental Research, Abstract pages, In Press
- Soory, M (2007) Periodontal disease severity and systemic diseases prevalent in a Caribbean catchment area of patients, West Indian Medical Journal, 56, 193-7
- Soory M (2007) Periodontal diseases and rheumatoid arthritis: A coincident model for therapeutic intervention, Current Drug Metabolism, 8, 750-7
- Clark DT, Soory M (2007) 5 alpha- reductase activity in Treponema Denticola, Oral Microbiology & Immunology, 22, 326-32
- Abo Elsaad N, Soory M, Louca C, Dunne S, Gadalla L (2007) Effect of soft laser on bone regeneration in the treatment of infrabony defects: A clinical and experimental study, Meeting of the European Society of Biomaterials, Abstract, In Press
- Al-Qattan T, Soory M (2007) Interaction of Emdogain, nicotine and glutathione in fibroblasts and osteoblasts, Congress of the British & Scandinavian Societies for Dental Research, British Society for Dental Research, J Dental Research, Abstract pages, In Press
- Tilakaratne A, Soory M (2006) Redox status of a hyperglycaemic cell culture model of osteoblasts supplemented with bacterial LPS and minocycline, Endocrine Society Meeting, British Endocrine Society Supplement 12, P44 Abstract
- Soory M, Tilakaratne A (2006) Oxidative stress induced by TNF-alpha and glucose in an osteoblastic model and therapeutic implications of minocycline, Endocrine Society Meeting, British Endocrine Society Supplement 12, P45 Abstract
- Figuero-Ruiz E, Soory M, Cerero R, Bascones A (2006) Oxidant / antioxidant interactions of nicotine, Coenzyme Q10, Pycnogenol and phytoestrogens in oral periosteal fibroblasts and MG63 osteoblasts, Steroids, 71 (0039-128X), 1062-72
- DT Clark, M Soory (2006) The influence of cholesterol, progesterone, 4-androstenedione and testosterone on the growth of Treponema denticola ATCC 33520 in batch cultures, Anaerobe, 12, 267-273
- Rahman, Z.A., Soory, M (2006) Antioxidant effects of glutathione and IGF in a hyperglycaemic cell culture model of fibroblasts: some actions of advanced glycaemic end products (AGE) and nicotine, Endocrine, Metabolic & Immune Disorders - Drug Targets, 6, 279-286
- Figuero-Ruiz E, Soory M, Bascones A (2006) Oxidant / antioxidant interactions of nicotine, coenzyme Q10, Pycnogenol and phytoestrogens, Europerio Meeting, Madrid, J Clin Periodontol 33 Suppl 7, 69 Abstract
- Soory M, Abou El Saad NSM (2006) Risk markers of metabolic syndrome in a Caribbean catchment area of periodontal patients in South East London, Caribbean Health Research Council Meeting, St. Kitts, West Indian Medical Journal, Suppl 2, 55, 59, P15 Abstract
- Soory M, Tilakaratne A (2006) Interactions of Lipopolysaccharide, Low Density Lipoprotein and Minocycline in Osteoblasts, International Association for Dental Research Meeting, Brisbane, J Dent Res supplement Abstract, In Press
- Soory M, Tilakaratne A (2006) An osteoblastic redox model simulating insulin resistance in periodontal patients, Pan European Federation Meeting, Dublin, International Association for Dental Research, J Dent Res supplement Abstract, In Press
- Clark DT, Soory M (2006) The metabolism of cholesterol and certain hormonal steroids by Treponema denticola, Steroids, 71, 352-363
- Soory M, Rahman Z (2005) Oxidative effects of advanced glycation end products (AGE) in a gingival fibroblast cell culture model, British Endocrine Society Meeting, Endocr Abs 10, DP2 Abstract
- Soory M, Rahman Z (2005) Modulation of nicotine and advanced glycation end product (AGE) mediated effects by the antioxidant glutathione (G) in fibroblasts, British Endocrine Society, Endocr Abs 10, DP3 Abstract
- Soory M, Butler-Smith L, Murphy L, White C (2005) Periodontal disease severity and systemic diseases prevalent in a Caribbean catchment area of patients, Caribbean Health Research Council Meeting, Tobago, West Indian Medical Journal , Suppl 2, 54, 80, P-72 Abstract
- Soory M, Biomarkers of Diabetes Mellitus and Rheumatoid Arthritis Associated With Oxidative Stress, Applicable to Periodontal Diseases, Current Topics in Steroid Research, invited review(4), 1-17, 2004
- Rahman Z, Soory M (2004) Modulation of the effects of glucose on fibroblasts by glutathione, British Society for Dental Research Meeting, J Dent Res (Spec Iss B) 83, 0072 Abstract
- Soory M, Tinti F (2004) Response of fibroblasts to hydrogen peroxide, glutathione and nicotine, International Association for Dental Research, Honolulu, J Dent Res (Spec Iss A) 83, 1616 Abstract
- Soory M (2004) Combating plaque biofilm for oral and systemic health, World Ehrlich Congress on anti-infectives, Nuremburg, World Conference on Magic Bullets, Page A-131, 515 Abstract
- Soory M, Suchak A (2003) TGF and IGF mediated response to serial concentrations of nicotine using androgen biomarkers in human gingival fibroblasts, British Endocrine Society Meeting, Joint Endocrinology & Diabetes Day, Endocrine Abs. 6, DP8 Abstract
- Soory M, Suchak A, Effects of alkaline phosphatase and its inhibitor levamisole on the modulation of androgen metabolism by nicotine and minocycline in human gingival and oral periosteal fibroblasts, Archives of Oral Biology, 48, 69-76, 2003
- Soory M, Tilakaratne A, The modulation of androgen metabolism by phenytoin, oestradiol and tamoxifen in human ginigval fibroblasts, Journal of Clinical Periodontology, 30, 556-61, 2003
- Soory M, Tilakaratne A, Androgen metabolic response to indomethacin and the alkaline phosphatase inhibitor levamisole in fibroblasts, Journal of Clinical Periodontology, 30, 1069-74, 2003
- Soory M, Tilakaratne A, Anabolic potential of fibroblasts from chronically inflamed gingivae grown in hyperglycaemic culture medium in the presence or absence of insulin and nicotine, Journal of Periodontology, 74, 1771-77, 2003
- Richard Palmer, Mena Soory (2003) Modifying factors: Diabetes, puberty, pregnancy and the menopause and tobacco smoking, Clinical Periodontology and Implant Dentistry, Fourth edition, UK, Blackwell Munksgaard, 179-197 pages, ISBN=1-4051-0236-5 (bookchapter)
- Soory M, Tilakaratne A (2003) Response of a hyperglycaemic cell culture model to transforming growth factor beta and alkaline phosphatase, using androgen biomarkers, International Association for Dental Research Meeting, Gothenburg, J Dent Res. (Spec Iss B) 82, 2219 Abstract
- Soory M, Suchak A (2003) Modulation of nicotine mediated responses in human gingival fibroblasts by PDGF and the alkaline phosphatase inhibitor levamisole, British Endocrine Society Meeting, Joint Endocrinology & Diabetes Day, Endocrine Abs. 6, DP7 Abstract
- Soory M, Suchak A (2002) Influence of nicotine on alkaline phosphatase mediated androgen metabolism in fibroblasts, British Endocrine Society Meeting, Endocrine Abs. 4, P83 Abstract
- Tilakaratne A, Soory M (2002) The effects of nicotine on androgen metabolism in fibroblasts mediated by oestradiol and the alkaline phosphatase inhibitor levamisole, British Endocrine Society Meeting, Endocrine Abs. 4, P81 Abstract
- Tilakaratne A, Soory M, Dexamethasone mediated androgen action in human gingival and orl periosteal fibroblasts, Archives of Oral Biology, 73, 585-90, 2002
- Tilakaratne A, Soory M, The modulation of androgen metabolism by oestradiol, minocycline and indomethacin in a cell culture model, Journal of Periodontology, 73, 585-90, 2002
- Soory M, Suchak A, Phenytoin mediated androgen metabolism in gingival fibroblasts; effects of the anti-androgen finasteride and the alkaline phosphatase inhibitor levamisole, Journal of Clinical Periodontology, 29, 955-60, 2002
- Soory, M, Hormone mediation of immune responses in the progression of diabetes, rheumatoid arthritis and periodontal diseases, Current Drug Targets - Immune, Endocrine & Metabolic Disorders, 2, 13-25, 2002
- Soory M, Tilakaratne A (2002) Androgen metabolic response to glucose, insulin and nicotine in fibroblasts, 12th International Conference on Periodontal Research, North Sea congress, Congress book Abstract
- Soory M, Tilakaratne A (2002) Androgen metabolism in fibroblasts, modulated by phenytoin and growth factors, Pan European Festival of Oral Science, Cardiff, International Association for Dental Research, J Dent Res Abstract
- Soory M, Tilakaratne A (2002) Effects of glucose, insulin, glucagon and nicotine on cultured fibroblast, British Endocrine Society Meeting, Diabetes Day, Endocrine Abs. 4, DP3 Abstract
- Tilakaratne A, Soory M (2002) Inhibition of dexamethasone mediated androgen metabolism by levamisole in oral periosteal fibroblasts, British Endocrine Society Meeting, Endocrine Abs. 4, P82 Abstract
- Soory M, Tilakaratne A (2001) Metabolism of androgen substrates by gingival fibroblasts in response to nicotine and oestradiol, British Endocrine Society Meeting, Endocrine Abs. 2 P86 Abstract
- Tilakaratne A, Soory M (2001) Modulation of androgen metabolism by oestradiol and finasteride in response to phenytoin in gingival fibroblasts, British Endocrine Society Meeting, Endocrine Abs. 2, P87 Abstract
- Tilakaratne A, Soory M, Modulation of androgen action by oestrogen in human gingival fibroblasts and the effects of the anti-androgen finasteride, Archives of Oral Biology, 46, 109-115, 2001
- Soory M, Suchak A, The effects of human mast cell products and of phenytoin on androgen 5 alpha reductase expression in human gingival fibroblasts, Archives of Oral Biology, 46, 847-855, 2001
- Tilakaratne A, Soory M, Modulatory effects of indomethacin on androgen metabolism in human gingival and oral periosteal fibroblasts, Steroids, 66, 857-63, 2001
- Tilakaratne A, Soory M, The action of finasteride - an inhibitor of 5 alpha reductase enzyme, on sex hormones in human oral periosteum, Sri-Lanka Dental Journal, 30, 13-23, 2001
- Suchak A, Soory M (2001) Implications of nicotine and adjunctive treatment with minocycline on fibroblasts, British Society for Dental Research, J Dent Res 80, (4) 1153, 95 Abstract
- Soory M, Suchak A (2001) Phenytoin mediated androgen metabolism in fibroblasts; effects of enzyme inhibitors, British Society for Dental Research, J Dent Res 80, (4) 1176, 274 Abstract
- Tilakaratne A, Soory M (2001) Modulation of androgen metabolism by phenytoin, oestradiol and tamoxifen in human gingival fibroblasts, New Millennium challenges in Periodontology in the Asian Pacific Region, Malaysia, Conference book Abs 26, 8 Abstract
- Tilakaratne A, Soory M (2001) Modulation of androgen metabolism by alkaline phosphatase and its inhibition by levamisole in oral periosteal fibroblasts, British Endocrine Society Meeting, Endocrine Abs. 2 P88, Abstract pages
- Soory M, Suchak A (2001) Effects of phenytoin, histamine and levamisole on androgen metabolism in gingival fibroblasts, British Endocrine Society Meeting, Endocrine Abs. 2 P89 Abstract
- Soory M, Tilakaratne A, The effect of minocycline on the metabolism of androgens by human oral periosteal fibroblasts and its inhibition by finasteride, Archives of Oral Biology, 45, 347-54, 2000
- Tilakaratne A, Soory M, Effects of the anti-androgen finasteride on 5alpha reduction of androgens in the presence of progesterone in human gingival fibroblasts; modulatory actions of the alkaline phosphatase inhibitor levami, Journal of Periodontal Research, 35, 179-185, 2000
- Tilakaratne A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, De Silva M, Effects of hormonal contraceptives on the periodontium, in a population of rural Sri-Lankan women, Journal of Clinical Periodontology, 27, 753-757, 2000
- Tilakaratne A, Soory M, Effects of oestradiol and progesterone on androgen metabolism in cultured human oral periosteal fibroblasts, Sri-Lanka Dental Journal, 29(1), 24-35, 2000
- Tilakaratne A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, De Silva M, Periodontal disease status during pregnancy and 3 months post-partum, in a rural population of Sri-Lankan women, Journal of Clinical Periodontology, 27, 787-792, 2000
- Soory M, Hormonal factors in periodontal disease, Dental Update, 27, 380-83, 2000
- Soory M, Targets for steroid hormone mediated actions of periodontal pathogens, cytokines and therapeutic agents: some implications on tissue turnover in the periodontium, Current Drug Targets, 1, 309-25, 2000
- Soory M, Tilakaratne A (2000) Alkaline phosphatase activity and indomethacin mediated androgen action in fibroblasts, British Society for Dental Research, J Dent Res 79 (Special issue) 312 , 1351 Abstract
- Suchak A, Soory M (2000) Implications of mast cell products on phenytoin-induced gingival overgrowth, British Society for Dental Research, J Dent Res 79, 1178 (57) Abstract
- Soory M, Tilakaratne A (2000) Modulation of androgen action by minocycline and oestradiol in human gingival fibroblasts, British Society for Dental Research, J Dent Res 79,1173 (21) Abstract
- Virdi H, Soory M (2000) The metabolism of 14C-testosterone by human gingival tissue; some effects of minocycline and the anti-androgen finasteride, British Endocrine Society Meeting, J. Endocrinol (supplement) 167, P78 Abstract
- Soory M, Virdi H (2000) Modulation of androgen action by minocycline and platelet derived growth factor (PDGF) in human gingival fibroblasts, British Endocrine Society Meeting, J. Endocrinol (supplement) 167, P35 Abstract
- Soory M, Virdi H (2000) Effects of transforming growth factor beta and minocycline on the metabolism of two androgen substrates by human gingival fibroblasts, British Endocrine Society Meeting, J Endocrinol (supplement) 167, P36 Abstract
- Tilakaratne A, Soory M (2000) Androgen mediated alkaline phosphatase (ALP) activity in human gingival and oral periosteal fibroblasts; inhibition by the alkaline phosphatase inhibitor levamisole, British Endocrine Society Meeting, J Endocrinol (supplement) 167, P77 Abstract
- Tilakaratne A, Soory M, Androgen metabolism in response to oestradiol 17 beta and progesterone in human gingival fibroblasts (HGF) in culture, Journal of Clinical Periodontology, 26, 723-31, 1999
- Tilakaratne A, Soory M, Anabolic implications of minocycline in human gingival fibroblasts mediated via the androgen metabolic pathway, J College Dent Stomatol Sri-Lanka, 8(1), 32-39, 1999
- Soory M, Virdi H, Implications of minocycline and growth factors, platelet derived growth factor and transforming growth factor beta on inflammatory repair in the periodontium, via the androgen metabolic pathway, Journal of Periodontology, 70, 1136-1143, 1999
- Tilakaratne A, Soory M, Modulation of androgen metabolism by oestradiol 17beta and progesterone, alone and in combination, in human gingival fibroblasts (HGF) in culture, Journal of Periodontology, 70, 1017-1025, 1999
- Soory M, Virdi H, The uptake of two androgen substrates by cultured gingival fibroblasts in response to minocycline and metabolic studies in a cell fre system, Archives of Oral Biology, 44, 215-222, 1999
- Tilakaratne A, Soory M (1999) Anabolic implications of dexamethasone in human gingival and periosteal fibroblasts, British Society for Dental Research, J Dent Res (Abs. No 37) 78, 1039 Abstract
- Soory M, Tilakaratne A (1999) Expression of steroid metabolising enzymes in human oral periosteal and gingival fibroblasts in response to indomethacin, British Endocrine Society Meeting, J Endocrinol (supplement) 163, 82 Abstract
- Soory M, Tilakaratne A (1999) The modulation of androgen metabolism by oestrogen and indomethacin using human gingival fibroblasts in culture, British Endocrine Society Meeting, J Endocrinol (supplement )163, 85 Abstract
- Tilakaratne A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, DeSilva M (1999) Effects of pregnancy on the periodontium, British Endocrine Society Meeting, J Endocrinol (supplement) 163, 84 Abstract
- Tilakaratne A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, DeSilva M (1999) Effects of hormonal contraceptives on the periodontium, British Endocrine Society Meeting, J Endocrinol (supplement) 163, 83 Abstract
- Soory M, Virdi H, Effects of the anti-androgen finasteride on 5 alpha reductase activity in human gingival fibroblasts in response to minocycline, Journal of Clinical Periodontology, 25, 67-73, 1998
- Kasasa SC, Soory M, The effect of PDGF, TGF beta and IGF in combination on androgen metabolism by fibroblasts, Journal of Clinical Periodontology, 25, 640-46, 1998
- Kasasa SC, Soory M, The effect of both PDGF and NADPH on the metabolism of 14C-testosterone by human gingival fibroblasts, Medical Science Research, 26, 209-211, 1998
- Soory M, Gower DB, The influence of prostaglandins on steroid conversions by human gingival fibroblasts, Journal of Periodontal Research, 33, 439-447, 1998
- Kasasa SC, Soory M, The combined effects of TGF beta, IGF and PDGF on 5 alpha reductase activity on androgen substrates in human gingival tissue, Inflammopharmacology, 6, 223-224, 1998
- Soory M, Tilakaratne A (1998) Inhibition of minocycline-induced 5alpha-reductase activity by finasteride, in periosteal fibroblasts, IV European Congress of Endocrinology; European Federation of Endocrine Societies, Seville, Bioscientifica P1-299 Abstract
- Tilakaratne A, Soory M (1998) Androgen metabolism in response to oestradiol-17beta and progesterone in human gingival fibroblasts in culture, British Society for Dental Research Meeting, J Dent Res (IADR abstracts) 77, 867 Abstract
- Soory M, Suchak A (1998) Effects of mast cell histamine on 5alpha -reduction of 14C-testosterone by human gingival fibroblasts, British Endocrine Society Meeting, J Endocrinol (supplement) 159, 71 Abstract
- Tilakaratne A, Soory M (1998) 5alpha- Reduction of androgen substrates in response to oestradiol-17beta and effects of the anti-androgen finasteride, British Endocrine Society Meeting, J Endocrinol (supplement) 159, 72 Abstract
- Tilakaratne A, Soory M (1998) Effects of the anti-androgen finasteride on 5alpha-reduction of androgens in the presence of progesterone, British Endocrine Society Meeting, J Endocrinol (supplement) 159, 73 Abstract
- Soory M, Suchak A (1998) The expression of 5alpha-reductase activity in human gingival fibroblasts (HGF) in response to nicotine, using androgen substrates, British Endocrine Society Meeting, J Endocrinol (supplement) 159, 74 Abstract
- Soory M, Kasasa SC, The effects of epidermal growth factor, interleukin-1 and phenytoin, alone and in combination, on C19 steroid conversions in fibroblasts, Journal of Periodontology, 68, 1997
- Soory M, Ahmad S, 5 alpha reductase activity in human gingival fibroblasts in response to bacterial culture supernatants, using 14C-4-androstenedione as substrate, Archives of Oral Biology, 42, 255-262, 1997
- Clark DT, Soory M (1997) Metabolism of testosterone, 4-androstenedione, progesterone, cholesterol, corticosterone and cortisol by Treponema denticola, British Society for Dental Research, J Dent Res 76, 5: 107 Abstract
- Soory M, Kasasa SC (1997) The effects of epidermal growth factor, interleukin-1 and phenytoin on C19 steroid conversions in fibroblasts, British Society for Dental Research, J Dent Res 76, 5: 1023 Abstract
- Tilakaratne A, Soory M (1997) The effects of oestradiol-17beta and progesterone on the metabolism of two androgen substrates in human gingival fibroblasts, British Endocrine Society, J Endocrinol (supplement) 155, 67 Abstract
- Soory M, Virdi H (1997) The metabolism of radiolabelled testosterone and 4-androstenedione by homogenates of cultured gingival fibroblasts in response to minocycline, British Endocrine Society, J Endocrinol (supplement) 155, 66 Abstract
- Kasasa S C and Soory M, The effect of interleukin-1 (IL-1) on androgen metabolism in human gingival tissue (HGT) and periodontal ligament (PDL), Journal of Clinical Periodontology, 23(5), 419-24, 1996
- Kasasa S C and Soory M, The synthesis of 5-alpha dihydrotestosterone from androgens by human gingival tissue and fibroblasts in culture in response to TGF-beta and PDGF, Journal of Periodontal Research, 31, 312-21, 1996
- Kasasa SC, Soory M (1996) The effect of growth factor combinations on androgen metabolism in gingival fibroblasts, British Sociey for Dental Research Meeting, J Dent Res 75: 1189 Abstract
- Clark DT, Soory M, Tinsley GF, Beighton D (1996) Metabolism of radiolabelled cholesterol by Treponema denticola, British Society for Dental Research Meeting, J Dent Res 75: 1189 Abstract
- Soory M (1996) Anabolic implications of minocycline in gingivae, British Society for Dental Research, J Dent Res 75: 1160 Abstract
- Soory M, Virdi H (1996) Effects of finasteride on 5alpha-reductase activity in human gingival fibroblasts in the presence or absence of minocycline, British Endocrine Society Meeting, J Endocrinol (suppl) 151: 93 Abstract
- Virdi H, Soory M (1996) Inhibition of 5alpha-reductase activity in human gingival fibroblasts by the antiandrogen finasteride, British Endocrine Society Meeting, J Endocrinol (suppl) 151: 92 Abstract
- Kasasa SC, Soory M (1996) The effect of both PDGF and NADPH on the metabolism of 14C-testosterone by human gingival fibroblasts, British Endocrine Society, J Endocrinol (suppl) 151: 94 Abstract
- Kasasa SC, Soory M, The response of human gingival fibroblasts to IL-1 in their metabolic conversions of two androgenic substrates, Archives of Oral Biology, 40(10), 979-981, 1995
- Soory M, Bacterial steroidogenesis by periodontal pathogens and the effect of bacterial enzymes on steroid conversions by human gingival fibroblasts in culture, Journal of Periodontal Research, 30, 124-31, 1995
- Kasasa S C and Soory M, The influence of insulin-like growth factor (IGF) on C19 steroid conversions by human gingivae and in cultured gingival fibroblasts, Journal of Periodontology, 66, 966-72, 1995
- Soory M, Ahmad S (1995) Metabolism of 14C-4-androstenedione by gingival tissue in response to bacterial culture supernatants, British Society for Dental Research Meeting, J Dent Res 74: 840 Abstract
- Kasasa SC, Soory M (1995) Effect of growth factors on androgen metabolism in gingival fibroblasts, World Congress on Inflammation, Brighton, Inflammation Res (Suppl.) 44:21 Abstract
- Clark DT, Soory M (1995) The cofactor requirement and pH optimum for 17beta-hydroxysteroid dehydrogenase activity of Treponema denticola, British Endocrine Society Meeting, J Endocrinol (Suppl.) 147: 103 Abstract
- Kasasa SC, Soory M (1995) Effect of platelet derived growth factor (PDGF) on utilisation of two androgenic substrates by gingivae, British Endocrine Society Meeting, J Endocrinol (Suppl.) 147: 101 Abstract
- Soory M, Ahmad S (1995) Steroid conversions of 14C-4-androstenedione by gingival fibroblasts in response to bacterial culture supernatants, British Endocrine Society Meeting, J Endocrinol (Suppl.) 147: 102 Abstract
- Soory M (1994) Effects of phenytoin and epidermal growth factor on 14C-4-androstenedione metabolism by fibroblasts, British Society for Dental Research Meeting, J Dent Res 73, 800 Abstract
- Kasasa SC, Soory M (1994) The effect of growth factors on C19 steroid metabolism by gingival fibroblasts, British Society for Dental Research Meeting, J Dent Res 73, 822 Abstract
- Kasasa SC, Soory M (1994) 14C-Testosterone metabolism by human gingival tissue in response to TGF-beta and IGF, British Endocrine Society Meeting, J Endocrinol 143, 32 (Supplement) Abstract
- Clark DT, Soory M (1994) The kinetic mechanism for 5alpha-reduction of testosterone by Treponema denticola, British Endocrine Society Meeting, J Endocrinol 143, 24 (Supplement) Abstract
- Clark DT, Soory M (1994) The kinetic mechanism for 5alpha-reduction of testosterone by Treponema denticola, British Endocrine Society Meeting, J Endocrinol 143, 24 (Supplement) Abstract
- Soory M & Gower DB, Metabolism & release of C19 steroids by human gingival fibroblasts in culture: effects of phenytoin, Medical Science Research, 21, 811-813, 1993
- Soory M, Current concepts in periodontal treatment (invited review), The General Dental Practitioner (Journal of the College of General Dental Practitioners of Sri-Lanka), 11, 26-31, 1993
- Soory M (1993) Effects of interleukin-1 and epidermal growth factor on steroid conversions in gingival tissue, British Society for Dental Research Meeting, J Dent Res 72, 703 Abstract
- Soory M, Ahmad S (1993) Metabolism of C19 steroids by gingival fibroblasts in response to inflammatory mediators, British Society for Dental Research Meeeting, J Dent Res 72, 739 Abstract
- Soory M (1993) Androgen metabolism of plaque bacteria, British Society for Dental Research Meeting, J Dent Res 72, 703 Abstract
- Kasasa SC, Soory M (1993) Effects of interleukin-1 on 14C-testosterone metabolism by gingivae and periodontal ligament, British Society for Dental Research Meeting, J Dent Res 72, 703 Abstract
- Soory M (1993) Effects of IL-1 and EGF on 14C-4-androstenedione metabolism in human gingival fibroblasts, British Endocrine Society Meeting, J Endocrinol 139, 19 (Supplement) Abstract
- Soory M (1993) The effect of transforming growth factor beta (TGF-beta) on testosterone metabolism in human gingival fibroblasts, British Endocrine Society Meeting, J Endocrinol 139, 103 (Supplement) Abstract
- Clark DT, Soory M (1993) 5alpha-Reductase activity of Treponema denticola., British Endocrine Society Meeting, J Endocrinol 139, 5 (Supplement) Abstract
- Soory M (1992) C19 steroid synthesis in gingivae in response to prostaglandin E2 (PGE2)., British Society for Dental Research Meeting, J Dent Res 72, 604 Abstract
- Soory M (1992) The effect of prostaglandins (PGE1 and PGE2) on steroidogenesis in human gingivae, British Endocrine Society Meeting, J Endocrinol 135, 15 (Supplement) Abstract
- Clark D, Soory M (1992) Metabolism of testosterone by Treponema denticola., British Endocrine Society Meeting, J Endocrinol 135, 14 (Supplement) Abstract
- Kasasa SC, Soory M (1992) A Comparison of the metabolism of testosterone by human gingival tissue and periodontal ligament, British Endocrine Society Meeting, J Endocrinol 135, 13 (Supplement) Abstract
- Soory M, Gower DB (1991) The influence of inflammatory mediators on the effects of phenytoin on steroidogenesis by human gingival fibroblasts., Biochemical Society Meeting, Biochem Soc Trans 19: 92-93 Abstract
- Soory M (1991) Effect of PGE1 on steroid uptake and release by gingival fibroblasts (GF)., British Society for Dental Research Meeting, J Dent Res 70, 4: 669 Abstract
- Soory M (1991) The influence of microbial culture supernatants on 5alpha -reductase activity in human gingival fibroblasts., British Endocrine Society Meeting, J Endocrinol 131: 72 (Suppl) Abstract
- Sooriyamoorthy M, Gower DB, Eley BM, Androgen metabolism in gingival hyperplasia induced by nifedipine and cyclosporine, Journal of Periodontal Research, 25, 25-30, 1990
- Soory M & Gower DB, Investigation of androgen metabolism by hyperplastic tissue fibroblasts in relation to phenytoin, Medical Science Research, 18, 835-837, 1990
- Soory M, Gower DB (1990) The effects of inflammatory mediators on steroid metabolism by gingival fibroblasts., British Society for Dental Research Meeting, J Dent Res 69: 958 Abstract
- Soory M, Gower DB (1990) Bacterial steroidogenesis and the effect of endotoxin on human gingival fibroblasts (HGF) in relation to phenytoin., British Endocrine Society Meeting, J Endocrinol 127: 46 (Suppl) Abstract
- Sooriyamoorthy M, Gower DB, Phenytoin stimulation of 5 alpha reductase activity in inflamed gingival fibroblasts, Medical Science Research, 17, 989-900, 1989
- Sooriyamoorthy M, Gower DB, Hormonal influences on gingival tissue: relationship to periodontal diseases (a review), Journal of Clinical Periodontology, 16, 201-208, 1989
- Sooriyamoorthy M, Gower DB, Drug-induced gingival overgrowth: clinical features and possible mechanisms (invited review), Medical Science Research, 17, 881-884, 1989
- Sooriyamoorthy M, Gower DB (1989) Effects of substrate concentration and co-factors on androgen metabolism in gingival fibroblast cultures: applications to phenytoin action in hyperplastic cells., British Endocrine Society Meeting, J Endocrinol 123: 129 (Suppl) Abstract
- Sooriyamoorthy M, Gower DB (1989) Phenytoin stimulation of testosterone metabolism in inflamed human gingival fibroblasts, Biochemical Society, Biochem Soc Trans 17: 1020-1021 Abstract
- Sooriyamoorthy M, Harvey W & Gower DB, The use of human gingival fibroblasts in culture for studying the effects of phenytoin on testosterone metabolism, Archives of Oral Biology, 33(5), 353-359, 1988
- Sooriyamoorthy M, Gower DB (1988) Uptake and release of C19 steroids by human gingival fibroblasts in culture, British Endocrine Society Meeting, J Endocrinol 119: 113 (Suppl) Abstract
- Sooriyamoorthy M, Gower DB (1988) Comparison of steroid metabolism in cultured human gingival fibroblasts, homogenates and sub-cellular fractions : some effects of phenytoin., Biochemical Society Meeting, Biochem Soc Trans 17: 556-557 Abstract
- Sooriyamoorthy M, Gower DB, Harvey W (1987) Selective stimulation by phenytoin of testosterone metabolism in human hyperplastic gingival fibroblasts, British Society for Dental Research Meeting, J Dent Res 66: 861 Abstract
- Sooriyamoorthy M, Gower DB, Harvey W (1986) Effect of phenytoin on testosterone metabolism by different human gingival fibroblast cell-lines, British Society for Dental Research Meeting, J Dent Res 65: 496 Abstract
- Sooriyamoorthy M, Harvey W, Gower DB (1984) Testosterone metabolism by human gingival fibroblasts in vitro., British Society for Dental Research Meeting, J Dent Res 63: 494 Abstract
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