Dr. Robert P. Witherspoon | |
Fred Hutchinson Cancer Research Center Clinical Research MemberAppointed: 2002 University of Washington School of Medicine Medicine Oncology ProfessorAppointed: 2005 Fred Hutchinson Cancer Research Center Seattle Cancer Care Alliance Transplant Clinic Medical DirectorAppointed: 2001 |  |
QualificationsM.S., Baylor University, 1970. M.D., Baylor College of Medicine, 1970. Expertise and Research InterestsMedical Oncology with a special interest in bone marrow transplantation for treatment of hematopoietic and non-hematopoietic disease. Immunologic recovery, graft-versus-host disease clinical trials, supportive care, secondary malignancies, and long term outcomes following hematopoietic stem cell transplantation. Treatment strategies for treatment-related myelodysplasia and leukemia.
KeywordsCOS Keywords:Hematology, Leukemia, Oncology, Stem Cells.Additional Terms:Hematopoietic Stem Cell Transplantation.Languages(Reading, Writing, Speaking)German: (Functional, Functional, Functional) Japanese: (Basic, Basic, Basic) MembershipsAmerican Cancer Society American College of Physicians American Society for Blood and Bone Marrow Transplantation American Society of Clinical Oncology American Society of Hematology American Society of Internal Medicine International Society for Experimental Hematology Phi Beta Kappa Sigma Xi, The Scientific Research Society Honors and AwardsSigma Xi, 1970,
Baylor University Medical Graduate Chapter
Phi Beta Kappa, 1965,
Wabash College
Magna cum laude, 1965,
Wabash College
Previous Positions1996-2000, Medical Director,
Fred Hutchinson Cancer Research Center,
Ambulatory Clinic
1993-1996, Medical Director,
Fred Hutchinson Cancer Research Center
1990-1993, Pre-admission Medical Director,
Fred Hutchinson Cancer Research Center,
Department of Medical Oncology
1984, Associate Member,
Fred Hutchinson Cancer Research Center,
Oncology,
Division of Clinical Research
1984, Associate Professor,
University of Washington,
School of Medicine,
Department of Medicine,
Division of Oncology
1979-1984, Assistant Member,
Fred Hutchinson Cancer Research Center,
Medical Oncology,
Division of Clinical Research
1978-1979, Associate Member,
Fred Hutchinson Cancer Research Center,
Department of Medical Oncology
1978-1984, Assistant Professor,
University of Washington,
School of Medicine,
Department of Medicine,
Division of Medical Oncology
1976-1978, Acting Instructor,
University of Washington,
School of Medicine,
Department of Medicine,
Division of Oncology
1974-1976, Major, U.S.A.-M.C., Assistant Chief,
Brooke Army Medical Center, Fort Sam Houston, Texas,
Oncology Service
1973-1974, Senior Fellow,
University of Washington,
School of Medicine,
Department of Medicine
1971-1973, Resident,
University of Washington,
School of Medicine,
Department of Medicine
1970-1971, Intern,
University of Washington,
School of Medicine,
Department of Medicine
Funding Received- National Institutes of Health/National Cancer Institute:
Adult Leukemia Reserch Center (PENDING),
Dec 1, 2001
to Nov 30, 2006.
- National Institutes of Health/National Heart, Lung, Blood Institute:
Stem Cell Transplanttion,
Aug 1, 2001
to Jul 31, 2006.
Publications- McDonald GB, McCune JS, Batchelder A, Cole S, Phillips B, Ren AG, Vicini P, Witherspoon R, Kalhorn TF, Slattery JT (Sep 2005) Metabolism-based cyclophosphamide dosing for hematopoietic cell
transplant., Clinical Pharmacology and Therapeutics, 78 (3), 298-308
 - Hallstrand TS, Sprenger JD, Agosti JM, Longton GM, Witherspoon RP, Henderson WR Jr (Nov 2004) Long-term acquisition of allergen-specific IgE and asthma following
allogeneic bone marrow transplantation from allergic
donors., Blood, 104 (10), 3086-90
 - Storek J, Dawson MA, Lim LC, Burman BE, Stevens-Ayers T, Viganego F, Herremans MM, Flowers ME, Witherspoon RP, Maloney DG, Boeckh M (Feb 2004) Efficacy of donor vaccination before hematopoietic cell transplantation
and recipient vaccination both before and early after
transplantation., Bone Marrow Transplantation, 33 (3), 337-46
 - Hegenbart U, Niederwieser D, Forman S, Holler E, Leiblein S, Johnston L, Ponisch W, Epner E, Witherspoon R, Blume K, Storb R (Nov 2003) Hematopoietic cell transplantation from related and unrelated donors after
minimal conditioning as a curative treatment modality for severe
paroxysmal nocturnal hemoglobinuria., Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation., 9 (11), 689-97
 - Deeg HJ, Storer B, Slattery JT, Anasetti C, Doney KC, Hansen JA, Kiem HP, Martin PJ, Petersdorf E, Radich JP, Sanders JE, Shulman HM, Warren EH, Witherspoon RP, Bryant EM, Chauncey TR, Getzendaner L, Storb R, Appelbaum FR, Conditioning with targeted busulfan and cyclophosphamide for hemopoietic
stem cell transplantation from related and unrelated donors in patients
with myelodysplastic syndrome, Blood, 100(4), 1201-7, Aug 2002
 - Koc S, Leisenring W, Flowers ME, Anasetti C, Deeg HJ, Nash RA, Sanders JE, Witherspoon RP, Storb R, Appelbaum FR, Martin PJ, Therapy for chronic graft-versus-host disease: a randomized trial
comparing cyclosporine plus prednisone versus prednisone
alone, Blood, 100(1), 48-51, July 2002
 - Platzbecker U, Gooley T, Anasetti C, Appelbaum FR, Clurman B, Doney K, Chauncey T, Flowers ME, Myerson D, Radich JP, Storb R, Witherspoon RP, Deeg HJ (Jul 2002) Curative therapy of advanced essential thrombocythemia or polycythemia
vera by hemopoietic stem cell transplantation., Leukemia & Lymphoma, 43 (7), 1409-14
 - Jurado M, Deeg HJ, Storer B, Anasetti C, Anderson JE, Bryant E, Chauncey T, Doney K, Flowers MED, Hansen J, Martin PJ, Nash RA, Petersdorf E, Radich J, Sale G, Sandmaier BM, Storb R, Wade J, Witherspoon R, Appelbaum FR, Hematopoietic stem cell transplantation for advanced myelodysplastic syndrome after conditioning with busulfan and fractionated total body irradiation is associated with low relapse rate but considera, Biology of Blood and Marrow Transplantation, 8(3), 161-169, 2002
- Kansu E, Gooley T, Flowers ME, Anasetti C, Deeg HJ, Nash RA, Sanders JE, Witherspoon RP, Appelbaum FR, Storb R, Martin PJ, Administration of cyclosporine for 24 months compared with 6 months for
prevention of chronic graft-versus-host disease: a prospective randomized
clinical trial, Blood, 98(13), 3868-70, December 2001
 - Storek J, Dawson MA, Storer B, Stevens-Ayers T, Maloney DG, Marr KA, Witherspoon RP, Bensinger W, Flowers ME, Martin P, Storb R, Appelbaum FR, Boeckh M, Immune reconstitution after allogeneic marrow transplantation compared
with blood stem cell transplantation, Blood, 97(11), 3380-9, June 2001
 - Witherspoon RP, Deeg HJ, Storer B., Anasetti C., Storb R., Appelbaum FR, Hematopoietic stem cell transplantation for treatment-related leukemia or myelodysplasia, Journal of Clinical Oncology, 19, 2134-2141, 2001
- Storek J, Dawson MA, Storer B, Stevens-Ayers T, Maloney DG, Marr KA, Witherspoon RP, Bensinger W, Flowers MED, Martin P, Storb R., Appelbaum FR, Boeckh M, Immune reconstitution after allogeneic marrow versus blood stem cell transplantation, Blood, 97, 3380-3389, 2001
- Storek J, Gooley T, Siadak M, Bensinger WI, Maloney DG, Chauncey TR, Flowers M, Sullivan KM, Witherspoon RP, Rowley SD, Hansen JA, Storb R, Appelbaum FR, Allogeneic peripheral blood stem cell transplantation may be associated
with a high risk of chronic graft-versus-host disease, Blood, 90(12), 4705-9, December 1997
 - Storb R, Leisenring W, Anasetti C, Appelbaum FR, Deeg HJ, Doney K, Martin P, Sullivan KM, Witherspoon R, Pettinger M, Bensinger W, Buckner CD, Clift R, Flowers ME, Hansen JA, Pepe M, Chauncey T, Sanders J, Thomas ED, Methotrexate and cyclosporine for graft-vs.-host disease prevention: what
length of therapy with cyclosporine?, Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 3(4), 194-201, October 1997
 - Deeg HJ, Lin D, Leisenring W, Boeckh M, Anasetti C, Appelbaum FR, Chauncey TR, Doney K, Flowers M, Martin P, Nash R, Schoch G, Sullivan KM, Witherspoon RP, Storb R, Cyclosporine or cyclosporine plus methylprednisolone for prophylaxis of graft-versus-host disease: a prospective, randomized trial., Blood, 89(10), 3880-7, 15 1997
 - Storb R, Leisenring W, Anasetti C, Appelbaum FR, Buckner CD, Bensinger WI, Chauncey T, Clift RA, Deeg HJ, Doney KC, Flowers ME, Hansen JA, Martin PJ, Sanders JE, Sullivan KM, Witherspoon RP, Long-term follow-up of allogeneic marrow transplants in patients with
aplastic anemia conditioned by cyclophosphamide combined with
antithymocyte globulin, Blood, 89(10), 3890-1, May 1997
 - Curtis RE, Rowlings PA, Deeg HJ, Shriner DA, Socie G, Travis LB, Horowitz MM, Witherspoon RP, Hoover RN, Sobocinski KA, Fraumeni JF Jr, Boice JD Jr, Solid cancers after bone marrow transplantation, The New England Journal of Medicine, 336(13), 897-904, March 1997
 - Storek J, Gooley T, Witherspoon RP, Sullivan KM, Storb R, Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts., American Journal of Hematology, 54(2), 131-8, 1997
 - Deeg HJ, Socie G, Schoch G, Henry-Amar M, Witherspoon RP, Devergie A, Sullivan KM, Gluckman E, Storb R, Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients., Blood, 87(1), 386-92, 1 1996
 - Anderson JE, Appelbaum FR, Schoch G, Gooley T, Anasetti C, Bensinger WI, Bryant E, Buckner CD, Chauncey TR, Clift RA, Doney K, Flowers M, Hansen JA, Martin PJ, Matthews DC, Sanders JE, Shulman H, Sullivan KM, Witherspoon RP, Storb R, Allogeneic marrow transplantation for refractory anemia: a comparison of two preparative regimens and analysis of prognostic factors., Blood, 87(1), 51-8, 1 1996
 - Storek J, Witherspoon RP, Storb R, T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life., Bone Marrow Transplantation, 16(3), 413-25, 1995
 - Witherspoon RP, Deeg HJ, Storb R, Secondary malignancies after marrow transplantation for leukemia or aplastic anemia., Transplantation, 57(10), 1413-8, 27 1994
 - Sanders JE, Storb R, Anasetti C, Deeg HJ, Doney K, Sullivan KM, Witherspoon RP, Hansen J, Marrow transplant experience for children with severe aplastic anemia, The American Journal of Pediatric Hematology/oncology, 16(1), 43-9, February 1994
 - Petersen FB, Buckner CD, Appelbaum FR, Sanders JE, Bensinger WI, Storb R, Deeg HJ, Witherspoon RP, Sullivan KM, Clift RA, et al., Etoposide, cyclophosphamide and fractionated total body irradiation as a
preparative regimen for marrow transplantation in patients with advanced
hematological malignancies: a phase I stud, Bone Marrow Transplantation, 10(1), 83-8, July 1992
 - Flowers ME, Doney KC, Storb R, Deeg HJ, Sanders JE, Sullivan KM, Bryant E, Witherspoon RP, Appelbaum FR, Buckner CD, et al., Marrow transplantation for Fanconi anemia with or without leukemic
transformation: an update of the Seattle experience, Bone Marrow Transplantation, 9(3), 167-73, March 1992
 - Petersen FB, Deeg HJ, Buckner CD, Appelbaum FR, Storb R, Clift RA, Sanders JE, Bensinger WI, Witherspoon RP, Sullivan KM, et al., Marrow transplantation following escalating doses of fractionated total
body irradiation and cyclophosphamide--a phase I trial, International Journal of Radiation Oncology, Biology, Physics, 23(5), 1027-32, 1992
 - Sullivan KM, Mori M, Sanders J, Siadak M, Witherspoon RP, Anasetti C, Appelbaum FR, Bensinger W, Bowden R, Buckner CD, et al., Late complications of allogeneic and autologous marrow transplantation, Bone Marrow Transplantation, 10 Suppl 1, 127-34, 1992
 - Sullivan KM, Kopecky KJ, Jocom J, Fisher L, Buckner CD, Meyers JD, Counts GW, Bowden RA, Peterson FB, Witherspoon RP, et al., Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin
in bone marrow transplantation, The New England Journal of Medicine, 323(11), 705-12, September 1990
 - Storb R, Pepe M, Anasetti C, Appelbaum FR, Beatty P, Doney K, Martin P, Stewart P, Sullivan KM, Witherspoon R, et al., What role for prednisone in prevention of acute graft-versus-host disease
in patients undergoing marrow transplants?, Blood, 76(5), 1037-45, September 1990
 - Loughran TP Jr, Sullivan K, Morton T, Beckham C, Schubert M, Witherspoon R, Sale G, Sanders J, Fisher L, Shulman H, et al., Value of day 100 screening studies for predicting the development of
chronic graft-versus-host disease after allogeneic bone marrow
transplantation, Blood, 76(1), 228-34, July 1990
 - Schubert MA, Sullivan KM, Schubert MM, Nims J, Hansen M, Sanders JE, O'Quigley J, Witherspoon RP, Buckner CD, Storb R, et al., Gynecological abnormalities following allogeneic bone marrow
transplantation, Bone Marrow Transplantation, 5(6), 425-30, June 1990
 - Flowers ME, Pepe MS, Longton G, Doney KC, Monroe D, Witherspoon RP, Sullivan KM, Storb R, Previous donor pregnancy as a risk factor for acute graft-versus-host
disease in patients with aplastic anaemia treated by allogeneic marrow
transplantation, British Journal of Haematology, 74(4), 492-6, April 1990
 - Petersen FB, Appelbaum FR, Hill R, Fisher LD, Bigelow CL, Sanders JE, Sullivan KM, Bensinger WI, Witherspoon RP, Storb R, et al., Autologous marrow transplantation for malignant lymphoma: a report of 101
cases from Seattle, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 8(4), 638-47, April 1990
 - Sanders J, Sullivan K, Witherspoon R, Doney K, Anasetti C, Beatty P, Petersen FB, Long term effects and quality of life in children and adults after marrow
transplantation, Bone Marrow Transplantation, 4 Suppl 4, 27-9, December 1989
 - Petersen FB, Buckner CD, Appelbaum FR, Clift RA, Sanders JE, Bensinger WI, Storb R, Witherspoon RP, Sullivan KM, Bearman SI, et al., Busulfan, cyclophosphamide and fractionated total body irradiation as a
preparatory regimen for marrow transplantation in patients with advanced
hematological malignancies: a phase I study, Bone Marrow Transplantation, 4(6), 617-23, November 1989
 - Sullivan KM, Witherspoon RP, Storb R, Buckner CD, Sanders J, Thomas ED, Long-term results of allogeneic bone marrow transplantation, Transplantation Proceedings, 21(1 Pt 3), 2926-8, February 1989
 - Sanders JE, Buckner CD, Sullivan K, Doney K, Appelbaum F, Witherspoon R, Anasetti C, Storb R, Thomas ED, Growth and development after bone marrow transplantation, Progress in Clinical and Biological Research, 309, 375-82, 1989
 - Agosti JM, Sprenger JD, Lum LG, Witherspoon RP, Fisher LD, Storb R, Henderson WR Jr, Transfer of allergen-specific IgE-mediated hypersensitivity with
allogeneic bone marrow transplantation, 319(25), 1623-8, December 1988
 - Anasetti C, Storb R, Longton G, Witherspoon R, Doney K, Sullivan KM, Thomas ED, Donor buffy coat cell infusion after marrow transplantation for aplastic
anemia, 72(3), 1099-100, September 1988
 - Martin PJ, Hansen JA, Torok-Storb B, Durnam D, Przepiorka D, O'Quigley J, Sanders J, Sullivan KM, Witherspoon RP, Deeg HJ, et al., Graft failure in patients receiving T cell-depleted HLA-identical
allogeneic marrow transplants, 3(5), 445-56, September 1988
 - Witherspoon RP, Sullivan KM, Lum LG, Goehle S, Atkinson MK, Ochs HD, Doney KC, Hansen JA, Sanders JE, Storb R, Use of thymic grafts or thymic factors to augment immunologic recovery
after bone marrow transplantation: brief report with 2 to 12 years'
follow-up, 3(5), 425-35, September 1988
 - Sanders JE, Buckner CD, Amos D, Levy W, Appelbaum FR, Doney K, Storb R, Sullivan KM, Witherspoon RP, Thomas ED, Ovarian function following marrow transplantation for aplastic anemia or
leukemia, 6(5), 813-8, May 1988
 - Doney K, Buckner CD, Kopecky KJ, Sanders JE, Appelbaum FR, Clift R, Sullivan K, Witherspoon R, Storb R, Thomas ED, Marrow transplantation for patients with acute lymphoblastic leukemia in
first marrow remission, 2(4), 355-63, December 1987
 - Witherspoon RP, Navari R, Storb R, Sullivan KM, Doney K, Beatty P, Lum LG, Thomas ED, Treatment of marrow graft recipients with thymopentin, 1(4), 365-71, April 1987
 - Doney K, Storb R, Buckner CD, McGuffin R, Witherspoon R, Deeg HJ, Appelbaum FR, Sullivan KM, Thomas ED, Treatment of aplastic anemia with antithymocyte globulin, high-dose
corticosteroids, and androgens, 15(3), 239-42, March 1987
 - Sullivan KM, Fefer A, Witherspoon R, Storb R, Buckner CD, Weiden P, Schoch G, Thomas ED, Graft-versus-leukemia in man: relationship of acute and chronic
graft-versus-host disease to relapse of acute leukemia following
allogeneic bone marrow transplantation, 244, 391-9, 1987
 - Deeg HJ, Sullivan KM, Buckner CD, Storb R, Appelbaum FR, Clift RA, Doney K, Sanders JE, Witherspoon RP, Thomas ED, Marrow transplantation for acute nonlymphoblastic leukemia in first
remission: toxicity and long-term follow-up of patients conditioned with
single dose or fractionated total body irradiat, 1(2), 151-7, December 1986
 - Sanders JE, Pritchard S, Mahoney P, Amos D, Buckner CD, Witherspoon RP, Deeg HJ, Doney KC, Sullivan KM, Appelbaum FR, et al., Growth and development following marrow transplantation for leukemia, 68(5), 1129-35, November 1986
 - Bolger GB, Sullivan KM, Storb R, Witherspoon RP, Weiden PL, Stewart P, Sanders J, Meyers JD, Martin PJ, Doney KC, et al., Second marrow infusion for poor graft function after allogeneic marrow
transplantation, 1(1), 21-30, May 1986
 - Doney K, Storb R, Buckner CD, Sanders J, Witherspoon R, Thomas ED, Marrow transplantation for treatment of pregnancy-associated aplastic
anemia, 13(10), 1080-3, November 1985
 - Kennedy MS, Deeg HJ, Storb R, Doney K, Sullivan KM, Witherspoon RP, Appelbaum FR, Stewart P, Sanders J, Buckner CD, et al., Treatment of acute graft-versus-host disease after allogeneic marrow
transplantation. Randomized study comparing corticosteroids and
cyclosporine, 78(6 Pt 1), 978-83, June 1985
 - Thomas ED, Sanders JE, Buckner CD, Papayannopoulou T, Borgna-Pignatti C, De Stefano P, Sullivan KM, Deeg HJ, Witherspoon RP, Appelbaum FR, et al., Marrow transplantation for thalassemia, 445, 417-27, 1985
 - Witherspoon RP, Storb R, Shulman H, Buckner CD, Deeg HJ, Clift RA, Sanders JE, Doney K, McDonald G, Sullivan KM, et al., Marrow transplantation in hepatitis-associated aplastic anemia, 17(3), 269-78, October 1984
 - Buckner CD, Clift RA, Sanders JE, Stewart P, Bensinger WI, Doney KC, Sullivan KM, Witherspoon RP, Deeg HJ, Appelbaum FR, et al., Marrow harvesting from normal donors, 64(3), 630-4, September 1984
 - Witherspoon RP, Deeg HJ, Lum LG, Ochs HD, Hansen JA, Thomas ED, Storb R, Immunologic recovery in human marrow graft recipients given cyclosporine
or methotrexate for the prevention of graft-versus-host
disease, 37(5), 456-61, May 1984
 - Witherspoon RP, Legha SS, Reimer RR, Talley RW, Stuckey WJ, Dixon DO, McCracken JD, Stephens RL, Oishi N, Phase II trial of amsacrine in metastatic or locally recurrent squamous
cell carcinoma from head and neck primaries: a Southwest Oncology Group
study, 68(2), 435-6, February 1984
 - Witherspoon RP, Matthews D, Storb R, Atkinson K, Cheever M, Deeg HJ, Doney K, Kalbfleisch J, Noel D, Prentice R, et al., Recovery of in vivo cellular immunity after human marrow grafting.
Influence of time postgrafting and acute graft-versus-host
disease, 37(2), 145-50, February 1984
 - Witherspoon RP, Hersman J, Storb R, Ochs H, Goldstein AL, McClure J, Noel D, Weiden PL, Thomas ED, Thymosin fraction 5 does not accelerate reconstitution of immunologic
reactivity after human marrow grafting, 55(4), 595-608, December 1983
 - Sanders JE, Buckner CD, Leonard JM, Sullivan KM, Witherspoon RP, Deeg HJ, Storb R, Thomas ED, Late effects on gonadal function of cyclophosphamide, total-body
irradiation, and marrow transplantation, 36(3), 252-5, September 1983
 - Izutsu KT, Sullivan KM, Schubert MM, Truelove EL, Shulman HM, Sale GE, Morton TH, Rice JC, Witherspoon RP, Storb R, Thomas ED, Disordered salivary immunoglobulin secretion and sodium transport in human
chronic graft-versus-host disease, 35(5), 441-6, May 1983
 - Atkinson K, Farewell V, Storb R, Tsoi MS, Sullivan KM, Witherspoon RP, Fefer A, Clift R, Goodell B, Thomas ED, Analysis of late infections after human bone marrow transplantation: role
of genotypic nonidentity between marrow donor and recipient and of
nonspecific suppressor cells in patients with c, 60(3), 714-20, September 1982
 - Cheever MA, Fefer A, Greenberg PD, Appelbaum F, Armitage JO, Buckner CD, Sale GE, Storb R, Witherspoon RP, Thomas ED, Treatment of hairy-cell leukemia with chemoradiotherapy and identical-twin
bone-marrow transplantation, 307(8), 479-81, August 1982
 - Storb R, Tsoi MS, Witherspoon RP, Sullivan K, Lum L, Deeg HJ, Atkinson K, Unique immunologic problems in human bone marrow transplant recipients, 13(3), 1624-7, September 1981
 - Witherspoon RP, Storb R, Ochs HD, Fluornoy N, Kopecky KJ, Sullivan KM, Deeg JH, Sosa R, Noel DR, Atkinson K, Thomas ED, Recovery of antibody production in human allogeneic marrow graft
recipients: influence of time posttransplantation, the presence or absence
of chronic graft-versus-host disease, and antith, 58(2), 360-8, August 1981
 - Sullivan KM, Shulman HM, Storb R, Weiden PL, Witherspoon RP, McDonald GB, Schubert MM, Atkinson K, Thomas ED, Chronic graft-versus-host disease in 52 patients: adverse natural course
and successful treatment with combination immunosuppression, 57(2), 267-76, February 1981

Profile DetailsIndividual Expertise profile of Robert P. Witherspoon, Copyright Robert P. Witherspoon. © COS Expertise TM, 2009, ProQuest LLC All rights reserved. |