Johns Hopkins University School of Medicine Medicine | |
QualificationsM.D., Johns Hopkins University, Medicine, 1998. Ph.D., University of Virginia, Chemistry, 1994. Expertise and Research InterestsI treat outpatients with HIV, HBV, and HCV infection. My laboratory studies the humoral and cellular immune response to HCV. In addition, we are involved in therapeutic and prophylactic HCV vaccine development. KeywordsCOS Keywords:Hepatitis, HIV, Immunology, Infectious Diseases Or Agents, Vaccine.Additional Terms:HIV, Hepatitis B Virus, Hepatitis C Virus, Immunology, Vaccine.Languages(Reading, Writing, Speaking)English: (Fluent, Fluent, Fluent) French: (Functional, Basic, Functional) MembershipsAmerican Association for the Study of Liver Diseases Infectious Diseases Society of America Funding Received- Dana Foundation Human Immunology Program:
Mechanisms of Immunologic Unresponsiveness to Hepatitis C Virus Infection,
$300,000,
2006
to 2009.
- Damon Runyon Clinical Investigator Award:
Analysis and Manipulation of Cross Reactive Immune Responses to Partial Escape Mutations in Chronic Hepatitis C Virus Infection.,
$450,000,
2006
to 2009.
- NIH:
Development of Listeria-Based Clinical Consensus HCV Vaccine Candidates,
,
2006
to 2009.
- NIH:
Clinical Core B and Immunology,
$2,700,000,
2005
to 2010.
- NIH:
Incident HIV infection and Immune Response to HCV,
$682,000,
2003
to 2008.
Publications- Barnes E, Salio M, Cerundolo V, Francesco L, Pardoll D, Klenerman P, Cox A (Mar 2008) Monocyte derived dendritic cells retain their functional capacity in patients following infection with hepatitis C virus., Journal of viral hepatitis, 15 (3), 219-28
 - Netski DM, Mosbruger T, Astemborski J, Mehta SH, Thomas DL, Cox AL (Mar 2007) CD4+ T cell-dependent reduction in hepatitis C virus-specific humoral immune responses after HIV infection., The Journal of infectious diseases, 195 (6), 857-63
 - Netski D, Mosbruger T, Depla E, Maertens G, Ray S, Hamilton R, Roundtree S, Thomas D, McKeating J, Cox A (2005) Humoral Immune Response in Acute Hepatitis C Virus Infection, Clinical Infectious Diseases, 41, 667-75
- Cox AL, Mosbruger T, Lauer GM, Pardoll D, Thomas DL, Ray SC (Jul 2005) Comprehensive analyses of CD8+ T cell responses during longitudinal study
of acute human hepatitis C, Hepatology (baltimore, Md.), 42 (1), 104-12
- Cox AL, Mosbruger T, Mao Q, Liu Z, Wang XH, Yang HC, Sidney J, Sette A, Pardoll D, Thomas DL, Ray SC (Jun 2005) Cellular immune selection with hepatitis C virus persistence in humans, The Journal of Experimental Medicine, 201 (11), 1741-52
- Cox A, Netski D, Mosbruger T, Sherman S, Strathdee S, Ompad D, Vlahov D, Chien D, Shyamala V, Ray S, Thomas D (2005) Prospective evaluation of community-acquired acute-phase hepatitis C virus infection, Clinical Infectious Diseases, 40, 951-958
- Mehta SH, Cox A, Hoover DR, Wang XH, Mao Q, Ray S, Strathdee SA, Vlahov D, Thomas DL (Apr 2002) Protection against persistence of hepatitis C, Lancet, 359 (9316), 1478-83
- Cox A, Carpenter C, Ticehurst J (2001) Non-A, B, or C Hepatitis, Current Treatment Options in Infectious Diseases, 3 (5), 440-455
- Cox A, Hellmann DB, Fishman E (1999) Acute Colonic ischaemia in a patient with systemic lupus erythematosis: diagnosis with spiral and computed tomographic angiography, Journal of Diagnostic Radiology and Imaging, 2 (1), 45-48
- Cox AL, Huczko E, Engelhard VH, Shabanowitz J, Hunt DF (1997) MHC Volume 1- A Practical Approach, Vol. Chapter 10, The application of mass spectrometry to the analysis of peptides bound to the MHC molecule, Oxford, Oxford Press
- Kaliyaperumal A, Falchetto R, Cox A, Dick R 2nd, Shabanowitz J, Chien YH, Matis L, Hunt DF, Bluestone JA (Sep 1995) Functional expression and recognition of nonclassical MHC class I T10b is
not peptide-dependent, Journal of Immunology (baltimore, Md. : 1950), 155 (5), 2379-86
- Slingluff CL Jr, Cox AL, Stover JM Jr, Moore MM, Hunt DF, Engelhard VH (May 1994) Cytotoxic T-lymphocyte response to autologous human squamous cell cancer
of the lung: epitope reconstitution with peptides extracted from
HLA-Aw68, Cancer Research, 54 (10), 2731-7
- Cox AL, Skipper J, Chen Y, Henderson RA, Darrow TL, Shabanowitz J, Engelhard VH, Hunt DF, Slingluff CL Jr (Apr 1994) Identification of a peptide recognized by five melanoma-specific human
cytotoxic T cell lines, Science, 264 (5159), 716-9
- Chen Y, Sidney J, Southwood S, Cox AL, Sakaguchi K, Henderson RA, Appella E, Hunt DF, Sette A, Engelhard VH (Mar 1994) Naturally processed peptides longer than nine amino acid residues bind to
the class I MHC molecule HLA-A2.1 with high affinity and in different
conformations, Journal of Immunology (baltimore, Md. : 1950), 152 (6), 2874-81
- Cox A, Henderson RA, Sakaguchi K, Appella E, Hunt DF, Engelhard VH (1993) Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells, Proceedings of the National Academy of Sciences of the USA, 90 (21), 10275-9
- Slingluff CL Jr, Cox AL, Henderson RA, Hunt DF, Engelhard VH (Apr 1993) Recognition of human melanoma cells by HLA-A2.1-restricted cytotoxic T
lymphocytes is mediated by at least six shared peptide
epitopes, Journal of Immunology (baltimore, Md. : 1950), 150 (7), 2955-63
- Hunt DF, Michel H, Dickinson TA, Shabanowitz J, Cox AL, Sakaguchi K, Appella E, Grey HM, Sette A (Jun 1992) Peptides presented to the immune system by the murine class II major
histocompatibility complex molecule I-Ad, Science, 256 (5065), 1817-20
- Hunt DF, Henderson RA, Shabanowitz J, Sakaguchi K, Michel H, Sevilir N, Cox AL, Appella E, Engelhard VH (Mar 1992) Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by
mass spectrometry, Science, 255 (5049), 1261-3
Profile DetailsCOS Expertise ID #1229272 Individual Expertise profile of Andrea L. Cox, Copyright Andrea L. Cox. © COS Expertise TM, 2008, ProQuest LLC All rights reserved. |