Dr. Andrea Manca

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University of York (United Kingdom)
Centre for Health Economics
Team for Economic Evaluation and HTA
Senior Research Fellow
Professional Headshot of Andrea  Manca

Mailing Address

Centre for Health Economics
University of York
Alcuin A-A116
Heslington
York, YO 10 5DD
United Kingdom

Contact Information

Phone: 0044 (0)1904 321430
Fax: 0044 (0)1904 321402
am126@york.ac.uk
http://www.york.ac.uk/inst/che/staff/manca.htm

Qualifications

Ph.D., University of York (United Kingdom), Economics, 2005.
M.Sc., University of York (United Kingdom), Health Economics, 1998.
Laurea, University of Rome Tor Vergata (Italy), Economics, 1996.

Expertise and Research Interests

Design and analysis of cost-effectiveness studies alongside randomized clinical trials
Statistical issues in trial-based cost-effectiveness analysis
Evidence synthesis methods for decision making in healthcare economic evaluation

Keywords

COS Keywords:

Clinical Trial, Decision Sciences, Economics, Health Care Economics, Medical Decision Making.

Additional Terms:

Analysis of Patient Level Data, Cost-effectiveness Analysis, Decision Modeling for CEA, Health Care Economic Evaluation.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
Italian: (Fluent, Fluent, Fluent)
Spanish: (Fluent, Functional, Fluent)

Memberships

International Health Economics Association
International Society for Pharmacoeconomics and Outcomes Research
Italian Association of Health Economics
UK Health Economics Study Group

Honors and Awards

2010-2014, Career Development Fellowship (NIHR-CDF), UK National Institute for Health Research
2008, Research Award for Methodology Excellence, International Society for Pharmacoeconomics and Outcomes Research (ISPOR)
2005, BackCare Research Award, Society for Back Pain Research
2004-2007, Health Services Research Training Fellowship, Wellcome Trust, Issues in the generalisability by location of the results of economic evaluation studies conducted alongside multinational and multicentre randomised controlled clinical trials
2001, Best post-graduate research project, National Research Council - Italy, Health Economics

Previous Positions

2004-2007, Wellcome Trust Training Fellow in Health Services Research, University of York (United Kingdom), Centre for Health Economics
1999, Research Fellow, University of York (United Kingdom), Centre for Health Economics

Publications

  • Manca A, Eldabe S, Buchser E, Kumar K, Taylor RS (Aug 2009) Relationship between Health-Related Quality of Life, Pain, and Functional Disability in Neuropathic Pain Patients with Failed Back Surgery Syndrome., Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research Abstract
  • Newman S, Cooke D, Casbard A, Walker S, Meredith S, Nunn A, Steed L, Manca A, Sculpher M, Barnard M, Kerr D, Weaver J, Ahlquist J, Hurel S (May 2009) A randomised controlled trial to compare minimally invasive glucose monitoring devices with conventional monitoring in the management of insulin-treated diabetes mellitus (MITRE)., Health technology assessment (Winchester, England), 13 (28), 1-216 Abstract
  • Cooke D, Hurel SJ, Casbard A, Steed L, Walker S, Meredith S, Nunn AJ, Manca A, Sculpher M, Barnard M, Kerr D, Weaver JU, Ahlquist J, Newman SP (May 2009) Randomized controlled trial to assess the impact of continuous glucose monitoring on HbA(1c) in insulin-treated diabetes (MITRE Study)., Diabetic medicine : a journal of the British Diabetic Association, 26 (5), 540-7 Abstract
  • Iglesias CP, Manca A, Torgerson D (2009) The health related quality of life and cost implications of falls in elderly women, Osteoporosis International, 20 (6), 869-78
  • Manca A (2009) Economic evaluation of medical devices and drugs - same or different? (Editorial), Value in Health, 12 (4), 401
  • Manca A (2009) Task Force Report on Good Research Practices on Economic Data Transferability in HTA (Editorial), Value in Health, 12 (4), 407
  • McKenna C, Bojke L, Manca A, Adebajo A, Dickson J, Helliwell P, Morton V, Russell I, Torgerson DJ, Watson J (2009) Shoulder Acute Pain in Primary Healthcare: Is Retraining GPs Effective (SAPPHIRE) randomised trial - cost effectiveness analysis, Rheumatology, 48 (5), 558-63
  • Augustovski F, Iglesias CP, Manca A, Drummond M, Rubinstein A, García Martí S (2009) Generalisability of Health Economic Evaluations in Latin America and the Caribbean Region, Pharmacoeconomics, In Press
  • Gauthier A, Manca A, Anton S (2009) Bayesian modelling of healthcare resource use in multinational randomised clinical trials, Pramacoeconomics, In Press
  • Austin PC, Manca A, Zwarenstein M, Juurlink DN, Stanbrook MB (2009) A substantial and confusing variation exists in handling of baseline covariates in randomized controlled trials: a review of trials published in leading medical journals, Journal of Clinical Epidemiology, In Press
  • Epstein D, Sculpher MJ, Manca A, Michaels J, Thompson SG, Brown LC, Powell JT, Buxton MJ, Greenhalgh RM (2008) Endovascular repair versus open repair in patients with abdominal aortic aneurysm: a modelling study to estimate long term cost-effectiveness, British Journal of Surgery, 17 (95(2)), 183-190
  • Epstein DM, Mason A, Manca A (2008) The hospital costs of care for stroke in nine European countries, Health Economics, 17, S21-S31
  • Manca A, Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O'Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, Taylor RJ, Goeree R, Sculpher MJ (2008) Quality of life, resource consumption and costs of spinal cord simulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial), European Journal of Pain, 12 (8), 1047-1058
  • Griffin SC, Barber JA, Manca A, Sculpher MJ, Thompson SG, Buxton MJ, Hemingway H (2007) Cost effectiveness of clinically appropriate decisions on alternative treatments for angina, British Medical Journal, 334 (7594), 624
  • Manca A, Lambert PC, Sculpher MJ, Rice N (2007) Cost-effectiveness analysis using data from multinational trials: the use of bivariate hierarchical modelling, Medical Decision Making, 27 (4), 471-90
  • Goeree R, Burke N, O'Reilly D, Manca A, Blackhouse G, Tarride JE (2007) Transferability of economic evaluations: approaches and factors to consider when using results from one geographic area for another, Current Medical Research and Opinion, 23 (4), 671-682
  • Manca A, Dumville J, Torgerson DJ, Klaber Moffett JA, Mooney MP, Jackson DA, Eaton S (2007) Randomised trial of two physiotherapy interventions for primary care back and neck pain patients: cost-effectiveness analysis, Rheumatology, 46 (9), 1495-501
  • Cicchetti A, Manca A, Ruggeri M (2007) L'utilizzo di modelli decisionali per le valutazioni economiche dei farmaci in Italia: stato dell'arte e prospettive future, Pharmacoeconomics (Italian Articles), 9 (2), 59-74
  • Dumville J, Manca A, Kitchener HC, Smith RB, Nelson L, Torgerson DJ, on behalf of the COLPO study group (2006) Cost-effectiveness analysis of open colposuspension versus laparoscopic colposuspension in the treatment of urodynamic stress incontinence, BJOG : An International Journal of Obstetrics and Gynaecology, 113, 1014-1022
  • Manca A, Epstein DM, Torgerson DL, Klaber Moffett JA, Coulton S, Farrin A, Hahn S, Jackson DA, Richmond S (2006) Randomised Trial of a Brief Physiotherapy Intervention Compared With Usual Physiotherapy for Neck Pain Patients: a Cost Effectiveness Analysis, International Journal of Technology Assessment in Health Care, 22 (1), 67-75
  • Urdahl H, Manca A, Sculpher MJ (2006) Assessing Generalisability in Model-Based Economic Evaluation Studies: A Structured Review in Osteoporosis, Pharmacoeconomics, 24 (12), 1181-97.
  • Manca A, Willan AR (2006) "Lost in translation": accounting for between-country differences in the analysis of multinational cost-effectiveness data, Pharmacoeconomics, 24 (11), 1101-1119
  • Manca A, Palmer S, Handling Missing Data in RCT-based Cost-effectiveness Analysis, Applied Health Economics and Health Policy, Adis, 4(2), 65-75, 2005
  • EVAR Trial Participants, Endovascular Aneurysm Repair and Outcome in Patients Unfit for Open Repair of Abdominal Aortic Aneurism (EVAR Trial 2): Randomised Controlled Trial, The Lancet, 365(9478), 2187-92, 25 Jun 2005
  • EVAR Trial Participants, Endovascular Aneurysm Repair Versus Open Repair in Patients With Abdominal Aortic Aneurism (EVAR Trial 1): Randomised Controlled Trial, The Lancet, 365(9478), 2179-86, 25 Jun 2005
  • Manca A, Hawkins N, Sculpher MJ, Estimating Mean QALYs in Trial-based Cost-effectiveness Analysis: The Importance of Controlling for Baseline Utility, Health Economics, 14(5), 487-96, May 2005
  • Manca A, Rice N, Sculpher MJ, Briggs AH, Assessing Generalisability By Location in Trial-based Cost-effectiveness Analysis: the Use of Multilevel Models, Health Economics, 14(5), 471-85, May 2005
  • Drummond MF, Manca A, Sculpher MJ. (01 Feb 2005) Increasing the Generalisability of Economic Evaluations. Recommendations for the Design, Analysis and Reporting of Studies, International Journal of Technology Assessment in Health Care, 21 (2), 165-71
  • Klaber Moffett JA, Jackson DA, Richmond SJ, Hahn S, Coulton S, Farrin A, Manca A, Torgerson DJ. (01 Jan 2005) Randomised trial of a brief physiotherapy intervention compared with usual physiotherapy for neck pain patients: outcomes and patient preference, British Medical Journal, 330 (7482), 75-80
  • Willan AR, Lin DY, Manca A, Regression Methods for Cost-effectiveness Analysis With Censored Data, Statistics in Medicine, 24(1), 131-45, Jan 2005
  • BEAM Trial investigators (10 Dec 2004) UK Back pain Exercise And Manipulation (UK BEAM) randomised trial: effectiveness of physical treatments for back pain in primary care, British Medical Journal, 329 (7479), 1377-1384
  • BEAM Trial Investigators (10 Dec 2004) UK Back pain Exercise And Manipulation (UKBEAM) randomised trial: cost-effectiveness of physical treatments for back pain in primary care, British Medical Journal, 329 (7479), 1381-1386
  • Richardson G, Manca A, Calculation of Quality-Adjusted Life Years in the published literature: A review of methodology and transparency, Health Economics, 13(12), 1203-1210, 05 Dec 2004
  • Sculpher MJ, Pang FS, Manca A, Drummond MF, Golder S, Urdahl H, Davies LM, Eastwood A., Generalisability in economic evaluation studies in healthcare: a review and case studies, Health Technol Assessment, 8(49), 1-206, Dec 2004
  • Garry R, Fountain J, Brown J, Manca A, Mason S, Sculpher M, Napp V, Bridgman S, Gray J, Lilford R, EVALUATE hysterectomy trial: a multicentre randomised trial comparing abdominal, vaginal and laparoscopic methods of hysterectomy, Health Technology Assessment (winchester, England), 8(26), 1-154, Jun 2004
  • Brown LC, Epstein D, Manca A, Beard JD, Powell JT, Greenhalgh RM (April 2004) The UK Endovascular Aneurysm Repair (EVAR) trials: design, methodology and progress, European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, 27 (4), 372-81
  • Sculpher M, Manca A, Abbott J, Fountain J, Mason S, Garry R (Jan 2004) Cost effectiveness analysis of laparoscopic hysterectomy compared with standard hysterectomy: results from a randomised trial, Bmj (clinical Research Ed.), 328 (7432), 134
  • Manca A, Sculpher MJ, Ward K, Hilton P (March 2003) A cost-utility analysis of tension-free vaginal tape versus colposuspension for primary urodynamic stress incontinence, Bjog : an International Journal of Obstetrics and Gynaecology, 110 (3), 255-62
  • Cunningham SJ, Sculpher M, Sassi F, Manca A (2003) A cost-utility analysis of patients undergoing orthognathic treatment for the management of dentofacial disharmony, The British Journal of Oral & Maxillofacial Surgery, 41 (1), 32-5
  • Ginnelly L, Manca A, The use of decision models in mental health economic evaluation: challenges and opportunities, Appl Health Econ Health Policy, 2(3), 157-64, 2003
  • Manca A, Sculpher MJ, Levonorgestrel-releasing Intrauterine System for Menorrhagia Improved Quality of Life but Cost Less than Hysterectomy. Commentary, Evidence Based Obstetrics & Gynaecology, 4(1), 24-25, 2002
  • Manca A, Davies LM, Burns A (2001) The cost-effectiveness of therapeutics for Alzheimer's disease, Psychopharmacology: The fifth Generation of Progress, Lippincott Williams & Wilkins (bookchapter)
  • Davies LM, Manca A (2001) The pharmacoeconomic aspects of dementia, Pharmacoeconomics in Psychiatry, Martin Dunitz (bookchapter)
  • Manca A , Davies LM (December 1999) An Economic Analysis of the Management of Alzheimer's Disease in the UK, The Journal of British Menopause Society, 4 (5), 167-173

Profile Details

Last Updated: 11/8/2009

COS Expertise ID #1155225
Reference this profile directly: http://myprofile.cos.com/am126