Dr. Anthony J. Rossini

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COS Expertise®
Novartis Pharma AG
Development
Biostatistics and Statistical Reporting
Modeling and Simulation
Expert Statistical ModelerAppointed: 2004
University of Washington
School of Medicine
Medical Education and Biomedical Informatics
Biomedical and Health Informatics
Research Associate ProfessorAppointed: 2004
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Biostatistics
Biostatistics
Joint Assistant MemberAppointed: 2000

Mailing Address

Muttenz, 4132
Switzerland

Contact Information

Qualifications

Sc.D., Harvard University, Biostatistics, 1994.
B.A., Rice University, Mathematics, 1989.

Expertise and Research Interests

Computers for statistical research and data analysis, and am involved in the design of user interfaces for making this job more efficient. Tasks of recent focus include novel tools for exploring the human/computing interface for data analysis, and the exploration of literate programming for data analysis (literate statistical analysis).

HIV vaccine trials design, immunology, sequence analysis, and Phase I/II trials design and analysis.

Vascular biology, especially genomic factors in plaque formation

Bioinformatics in general, and statistical methods for large scale data aquisition technologies (gene expression, proteomics, flow cytometry). I am a core member of the Bioconductor project (http://www.bioconductor.org/).

PK/PD modeling and simulation in the context of clinical trials and drug development.

Other Expertise

Academic Experience:
Associate Editor, Journal of Statistical Software
Associate Editor, Journal of Computational and Graphical Statistics
Column Editor (Computing): Chance Magazine

Industrial Relevance

Modeling and Simulation (biological, pharmacological, clinical).

Keywords

COS Keywords:

Biostatistics, Clinical Trial, Computer and Information Sciences, Computer Interface, Data Analysis, Data Systems, Statistics, Vascular Biology.

Additional Terms:

Biostatistics, Censored and Missing Data, Computational Statistics, Discrete Data, Network Analysis (Social/Sexual), Semiparametric Models, Statistical Computing Environments, Survival Analysis.

Languages

(Reading, Writing, Speaking)

German: (Functional, Basic, Basic)
Chinese, Mandarin: (Basic, Basic, None)

Memberships

American Statistical Association
Biometric Society
Institute for Mathematical Statistics

Previous Positions

2003-2003, Associate Professor, University of Copenhagen, Public Health, Biostatistics
2003-2004, Research Assistant Professor, University of Washington, School of Medicine, Medical Education, Biomedical and Health Informatics
1998-2003, Research Assistant Professor, University of Washington, School of Public Health and Community Medicine, Biostatistics
1995-1997, Assistant Professor, University of South Carolina, Science and Mathematics, Statistics
1994-1995, Visiting Assistant Professor, Pennsylvania State University, Medical College

Publications

  • Kussick SJ, Fromm JR, Rossini A, Li Y, Chang A, Norwood TH, Wood BL (Aug 2005) Four-color flow cytometry shows strong concordance with bone marrow morphology and cytogenetics in the evaluation for myelodysplasia., American Journal of Clinical Pathology, 124 (2), 170-81 Abstract
  • Van Eaton EG, Horvath KD, Lober WB, Rossini AJ, Pellegrini CA (Apr 2005) A randomized, controlled trial evaluating the impact of a computerized rounding and sign-out system on continuity of care and resident work hours., Journal of the American College of Surgeons, 200 (4), 538-45 Abstract
  • Spielberg F, Branson BM, Goldbaum GM, Lockhart D, Kurth A, Rossini A, Wood RW (Mar 2005) Choosing HIV Counseling and Testing Strategies for Outreach Settings: A Randomized Trial., Journal of Acquired Immune Deficiency Syndromes (1999), 38 (3), 348-55 Abstract
  • Gilbert PB, Rossini AJ, Shankarappa R (Mar 2005) Two-sample tests for comparing intra-individual genetic sequence diversity between populations., Biometrics, 61 (1), 106-17 Abstract
  • de Bruyn G, Rossini AJ, Chiu YL, Holman D, Elizaga ML, Frey SE, Burke D, Evans TG, Corey L, Keefer MC (Jan 2004) Safety profile of recombinant canarypox HIV vaccines., Vaccine, 22 (5-6), 704-13 Abstract
  • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J (2004) Bioconductor: open software development for computational biology and bioinformatics., Genome Biology, 5 (10), R80 Abstract
  • Spielberg F, Goldbaum GM, Lockhart D, Kurth A, Celum CL, Rossini A, Critchlow CW, Wood RW (Mar 2003) Overcoming barriers to HIV testing: preferences for new strategies among clients of a needle exchange, a sexually transmitted disease clinic, and sex venues for men who have sex with men., Journal of Acquired Immune Deficiency Syndromes (1999), 32 (3), 318-27 Abstract
  • Mei H, Tarczy-Hornoch P, Mork P, Rossini AJ, Shaker R, Donelson L (2003) Expression array annotation using the BioMediator biological data integration system and the BioConductor analytic platform., Amia ... Annual Symposium Proceedings [electronic Resource] / Amia Symposium. Amia Symposium., 445-9 Abstract
  • Geary RL, Wong JM, Rossini A, Schwartz SM, Adams LD (Dec 2002) Expression profiling identifies 147 genes contributing to a unique primate neointimal smooth muscle cell phenotype., Arteriosclerosis, Thrombosis, and Vascular Biology, 22 (12), 2010-6 Abstract
  • Murphy, S. , Rossini, A.J. and van der Vaart, A., Maximum Likelihood Estimation in the Proportional Odds Model, Journal of the American Statistical Association, September 1997
  • Huang, J. and Rossini, A.J. ,, Sieve Estimation for the Proportional Odds Failure-Time Regression Model with Interval Censoring, Journal of the American Statistical Association, September 1997
  • Vannucci RC, Rossini A, Towfighi J, Vannucci SJ (1997) Measuring the accentuation of the brain damage that arises from perinatal cerebral hypoxia-ischemia., Biology of the Neonate, 72 (3), 187-91 Abstract
  • L.-J. Sally Liu, and Rossini, A.J., Use of kriging models to predict 12-h mean ozone concentrations in metropolitan Toronto -- A pilot study, Environment International, 22, 677--692, November 1996
  • Manni A, Buckwalter E, Etindi R, Kunselman S, Rossini A, Mauger D, Dabbs D, Demers L (Sep 1996) Induction of a less aggressive breast cancer phenotype by protein kinase C-alpha and -beta overexpression., Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research., 7 (9), 1187-98 Abstract
  • Manni A, Buckwalter E, Etindi R, Kunselman S, Rossini A, Mauger D, Dabbs D, Demers L (Sep 1996) Induction of a less aggressive breast cancer phenotype by protein kinase C-alpha and -beta overexpression., Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research., 7 (9), 1187-98 Abstract
  • Vannucci RC, Rossini A, Towfighi J (Aug 1996) Effect of hyperglycemia on ischemic brain damage during hypothermic circulatory arrest in newborn dogs., Pediatric Research, 40 (2), 177-84 Abstract
  • Rossini, A.J. and Tsiatis, A.A., A Semiparametric Proportional Odds Regression Model for the Analysis of Current Status Data, Journal of the American Statistical Association, 91, 713-721, June 1996
  • Rossini, A.J., Wei, L.J., and Ying, Z., Checking Adequacy Of the Semiparametric Location Shift Model With Censored Data, Lifetime Data Analysis, 2, 145-157, 1996
  • Rossini AJ, Wei LJ, Ying Z (1996) Checking adequacy of the semiparametric location shift model with censored data., Lifetime Data Analysis, 2 (2), 145-57 Abstract

Profile Details

Last Updated: 5/14/2006

COS Expertise ID #649216
Reference this profile directly: http://myprofile.cos.com/arossini