Sandra M. Bajjalieh

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University of Washington
School of Medicine
Pharmacology
Associate Professor
Professional Headshot of Sandra M. Bajjalieh

Mailing Address

Box 357280
D429 Health Science Building
Seattle, Washington 98195-7280
United States

Contact Information

Phone: (206) 616-2962
Fax: (206) 685-3822
bajjalie@u.washington.edu

Qualifications

Ph.D., University of Wisconsin-Madison, 1989.
M.S., University of Illinois at Urbana-Champaign, 1983.
B.A., University of Illinois at Urbana-Champaign, 1975.

Expertise and Research Interests

Molecular mechanisms of neurotransmission
Lipid signaling
Neuronal cell biology
Synaptic vesicle protein quantificaiton

Industrial Relevance

One of the proteins the lab is studying, SV2, is the site of action of a novel class of anti-epilepsy drugs.

Keywords

COS Keywords:

Amino Acids, Brain, Cell Biology, Central Nervous System, Membranes, Nervous System, Neurobiology, Neurons, Neurotransmitters, Pharmacology, Proteins and Macromolecules.

Additional Terms:

Brain, Cell Biology, Central Nervous System, Nervous System, Neurobiology, Neurons, Synapses.

Publications

  • Custer KL, Austin NS, Sullivan JM, Bajjalieh SM (2006) Synaptic vesicle protein 2 enhances release probability at quiescent synapses, Journal of Neuroscience, 26 (4), 1303
  • Bajjalieh S (May 2005) A new view of an old pore., Cell, 121 (4), 496-7 Abstract
  • Schivell AE, Mochida S, Kensel-Hammes P, Custer KL, Bajjalieh SM (May 2005) SV2A and SV2C contain a unique synaptotagmin-binding site., Molecular and Cellular Neurosciences, 29 (1), 56-64 Abstract
  • Waggoner DW, Johnson LB, Mann PC, Morris V, Guastella J, Bajjalieh SM (Sep 2004) MuLK, a eukaryotic multi-substrate lipid kinase., The Journal of Biological Chemistry, 279 (37), 38228-35 Abstract
  • Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B (Jun 2004) The synaptic vesicle protein SV2A is the binding site for the, Proceedings of the National Academy of Sciences of the United States of America., 101 (26), 9861-6 Abstract
  • Bajjalieh S, Trafficking in cell fate., Nature Genetics, 36(3), 216-7, Mar 2004 Abstract
  • Xu, T. and Bajjalieh, S. M., Synaptic vesicle protein 2 (SV2) modulates the size of the readily releasable pool of secretory vesicles, Nature Cell Biology, 3: 691-698, 2001
  • Pyle RA, Schivell AE, Hidaka H, Bajjalieh SM, Phosphorylation of synaptic vesicle protein 2 modulates binding to synaptotagmin, Journal of Biological Chemistry, 275(22), 17195-200, 2000 Abstract
  • Crowder KM, Gunther JM, Jones TA, Hale BD, Zhang HZ, Peterson MR, Scheller RH, Chavkin C, Bajjalieh SM, Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A \(SV2A\)., Proceedings of the National Academy of Sciences (USA), 96(26), 15268-73, 21 Dec 1999 Abstract
  • Bajjalieh SM, Synaptic vesicle docking and fusion, Current Opinion in Neurobiology, 9(3), 321-8, June 1999 Abstract
  • Schivell AE, Batchelor RH, Bajjalieh SM, Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin, Journal of Biological Chemistry, 271(44), 27770-5, 1996 Abstract

Profile Details

Last Verified: 2/10/2006

COS Expertise ID #307282
Reference this profile directly: http://myprofile.cos.com/bajjalis82