Dr. Brian F. Volkman

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Medical College of Wisconsin
Biochemistry
Assistant ProfessorAppointed: 2000
Professional Headshot of Brian F. Volkman

Mailing Address

Medical College of Wisconsin
8701 Watertown Plank Rd.
Milwaukee, Wisconsin 53226
United States

Contact Information

Phone: (414) 456-8400
Fax: (414) 456-6510
bvolkman@mcw.edu
http://www.biochem.mcw.edu/people/faculty/volkman/

Qualifications

Ph.D., University of California, Berkeley, Chemistry, 1994.
B.S., Butler University, Chemistry, Physics, 1989.

Expertise and Research Interests

Structural biology of immunological signaling molecules using NMR spectroscopy
Structural genomics

Keywords

COS Keywords:

Protein Structure, Proteomics, Spectroscopy.

Additional Terms:

Dynamics, NMR, Protein Structure, Proteomics.

Memberships

American Association for the Advancement of Science
American Chemical Society

Previous Positions

1997-2000, Assistant Scientist, University of Wisconsin-Madison, College of Agricultural and Life Sciences, Biochemistry

Funding Received

  • National Institutes of Health (NIH): Structure of the Human Chemokine Lymphotactin, $192,692, Aug 1, 1999 to Jul 31, 2002.

Publications

  • Markley JL, Ulrich EL, Westler WM, Volkman BF, Macromolecular structure determination by NMR spectroscopy, Methods of Biochemical Analysis, 44, 89-113, 2003 Abstract
  • Volkman BF, Prehoda KE, Scott JA, Peterson FC, Lim WA, Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome, Cell, 111(4), 565-76, November 2002 Abstract
  • Goodfellow BJ, Nunes SG, Rusnak F, Moura I, Ascenso C, Moura JJ, Volkman BF, Markley JL, Zinc-substituted Desulfovibrio gigas desulforedoxins: resolving subunit degeneracy with nonsymmetric pseudocontact shifts, Protein Science : a Publication of the Protein Society, 11(10), 2464-70, October 2002 Abstract
  • Kuloglu ES, McCaslin DR, Markley JL, Volkman BF, Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions, Journal of Biological Chemistry, 277(20), 17863-70, May 2002 Abstract
  • Skjeldal L, Gran L, Sletten K, Volkman BF, Refined structure and metal binding site of the kalata B1 peptide, Archives of Biochemistry and Biophysics, 399(2), 142-8, March 2002 Abstract
  • Clark KD, Volkman BF, Thoetkiattikul H, Hayakawa Y, Strand MR, N-terminal residues of plasmatocyte-spreading peptide possess specific determinants required for biological activity, Journal of Biological Chemistry, 276(40), 37431-5, October 2001 Abstract
  • Kuloglu ES, McCaslin DR, Kitabwalla M, Pauza CD, Markley JL, Volkman BF, Monomeric solution structure of the prototypical 'C' chemokine lymphotactin, Biochemistry, 40(42), 12486-96, October 2001 Abstract
  • Volkman BF, Zhang Q, Debabov DV, Rivera E, Kresheck GC, Neuhaus FC, Biosynthesis of D-alanyl-lipoteichoic acid: the tertiary structure of apo-D-alanyl carrier protein, Biochemistry, 40(27), 7964-72, July 2001 Abstract
  • Clark KD, Volkman BF, Thoetkiattikul H, King D, Hayakawa Y, Strand MR, Alanine-scanning mutagenesis of plasmatocyte spreading peptide identifies critical residues for biological activity, Journal of Biological Chemistry, 276(21), 18491-6, May 2001 Abstract
  • Volkman BF, Lipson D, Wemmer DE, Kern D, Two-state allosteric behavior in a single-domain signaling protein, Science, 291(5512), 2429-33, March 2001 Abstract
  • Lytle BL, Volkman BF, Westler WM, Heckman MP, Wu JH, Solution structure of a type I dockerin domain, a novel prokaryotic, extracellular calcium-binding domain, Journal of Molecular Biology, 307(3), 745-53, March 2001 Abstract
  • Baldisseri DM, Margolis JW, Omotosho PA, Volkman BF, Margolis FL, Sequence-specific NMR resonance assignments of the backbone atoms for the olfactory marker protein, OMP, Journal of Biomolecular Nmr, 17(4), 353-4, August 2000 Abstract
  • Lytle BL, Volkman BF, Westler WM, Wu JH, Secondary structure and calcium-induced folding of the Clostridium thermocellum dockerin domain determined by NMR spectroscopy, Archives of Biochemistry and Biophysics, 379(2), 237-44, July 2000 Abstract
  • Kern D, Volkman BF, Luginbuhl P, Nohaile MJ, Kustu S, Wemmer DE, Structure of a transiently phosphorylated switch in bacterial signal transduction, Nature, 402(6764), 894-8, December 1999 Abstract
  • Babu CR, Volkman BF, Bullerjahn GS, NMR solution structure of plastocyanin from the photosynthetic prokaryote, Prochlorothrix hollandica, Biochemistry, 38(16), 4988-95, April 1999 Abstract
  • Volkman BF, Anderson ME, Clark KD, Hayakawa Y, Strand MR, Markley JL, Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens, Journal of Biological Chemistry, 274(8), 4493-6, February 1999 Abstract
  • Volkman, B. F., Wilkens, S. J., Lee, A. L., Xia, B., Westler, W. M., Beger, R. D., and Markley, J. L., Redox-dependent magnetic alignment of Clostridium pasterianum rubredoxin: measurement of magnetic susceptibility anisotropy and prediction of pseudocontact shift contributions, Journal of the American Chemical Society, 121, 4677-4683, 1999
  • Beger RD, Marathias VM, Volkman BF, Bolton PH, Determination of internuclear angles of DNA using paramagnetic-assisted magnetic alignment, Journal of Magnetic Resonance, 135(1), 256-9, November 1998 Abstract
  • Chylla RA, Volkman BF, Markley JL, Practical model fitting approaches to the direct extraction of NMR parameters simultaneously from all dimensions of multidimensional NMR spectra, Journal of Biomolecular Nmr, 12(2), 277-97, August 1998 Abstract
  • Volkman BF, Alam SL, Satterlee JD, Markley JL, Solution structure and backbone dynamics of component IV Glycera dibranchiata monomeric hemoglobin-CO, Biochemistry, 37(31), 10906-19, August 1998 Abstract
  • Xia B, Volkman BF, Markley JL, Evidence for oxidation-state-dependent conformational changes in human ferredoxin from multinuclear, multidimensional NMR spectroscopy, Biochemistry, 37(11), 3965-73, March 1998 Abstract
  • Geierstanger B, Jamin M, Volkman BF, Baldwin RL, Protonation behavior of histidine 24 and histidine 119 in forming the pH 4 folding intermediate of apomyoglobin, Biochemistry, 37(12), 4254-65, March 1998 Abstract
  • Alam SL, Volkman BF, Markley JL, Satterlee JD, Detailed NMR analysis of the heme-protein interactions in component IV Glycera dibranchiata monomeric hemoglobin-CO, Journal of Biomolecular Nmr, 11(2), 119-33, February 1998 Abstract
  • Volkman BF, Prantner AM, Wilkens SJ, Xia B, Markley JL, Assignment of 1H, 13C, and 15N signals of oxidized Clostridium pasteurianum rubredoxin, Journal of Biomolecular Nmr, 10(4), 409-10, December 1997 Abstract
  • Prantner AM, Volkman BF, Wilkens SJ, Xia B, Markley JL, Assignment of 1H, 13C, and 15N signals of reduced Clostridium pasteurianum rubredoxin: oxidation state-dependent changes in chemical shifts and relaxation rates, Journal of Biomolecular Nmr, 10(4), 411-2, December 1997 Abstract
  • Chivers PT, Prehoda KE, Volkman BF, Kim BM, Markley JL, Raines RT, Microscopic pKa values of Escherichia coli thioredoxin, Biochemistry, 36(48), 14985-91, December 1997 Abstract
  • Lee AL, Volkman BF, Robertson SA, Rudner DZ, Barbash DA, Cline TW, Kanaar R, Rio DC, Wemmer DE, Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sex-lethal, Biochemistry, 36(47), 14306-17, November 1997 Abstract
  • Volkman BF, Wemmer DE, Deletion of a single amino acid changes the folding of an apamin hybrid sequence peptide to that of endothelin, Biopolymers, 41(4), 451-60, April 1997 Abstract
  • Volkman BF, Nohaile MJ, Amy NK, Kustu S, Wemmer DE, Three-dimensional solution structure of the N-terminal receiver domain of NTRC, Biochemistry, 34(4), 1413-24, January 1995 Abstract
  • Geierstanger BH, Volkman BF, Kremer W, Wemmer DE, Short peptide fragments derived from HMG-I/Y proteins bind specifically to the minor groove of DNA, Biochemistry, 33(17), 5347-55, May 1994 Abstract

Profile Details

Last Updated: 8/15/2003

COS Expertise ID #831483
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