University at Buffalo School of Medicine and Biomedical Sciences Medicine Cardiology Professor (Gft) | |
QualificationsM.D., University at Buffalo, 1979. B.S., Rensselaer Polytechnic Institute, 1975. Expertise and Research InterestsMy main area of expertise is cardiovascular diseases.
Other ExpertiseAcademic Experience: Fellow, American College of Cardiology Fellow, American College of Physicians Council on Circulation, American Heart Association
Honors and Awards: Alpha Omega Alpha James A. Gibson Anatomical Society Tau Beta Pi Engineering Honorary Society Buswell Student Research Award, SUNYAB School of Medicine, 1978 John Watson Award in Medicine, SUNYAB School of Medicine, 1979 Upjohn Research Award, SUNYAB School of Medicine, 1979 John C. Sable Memorial Heart Fund Award, 1982 American Heart Association Louis N. Katz Award Finalist, In vivo coronary input impedance, capacitance and conductance; influences on diastolic pressure-flow relationships, 1982 National American Heart Association Annual Scientific Session Sinsheimer Scholar, 1983
Business Experience: State University of New York at Buffalo: Member, Laboratory Animal Care Committee, l984-87 Member, Cardiovascular Task Force, l987-1989 Member, Ad hoc Health Sciences Instruments Shops Committee, 1989-1990 Member, Residency Training Program Committee, 1989 Member, BRSG/Research Development Funds Review Committee, 1989-1990 Member, Cardiology Search Committee for Millard Fillmore Hospital, 1989 Member, Task Force of Information Systems Council, 1991 Member, PET Cardiac Advisory Subcommittee, 1991 Member, Ad hoc Department of Physiology Site Visit Committee, 1991 Member, Ad hoc IFR Policy Committee, Department of Medicine, 1992 Member, Housestaff Evaluation Committee, Department of Medicine, 1990-1994 Member, School of Medicine, Adhoc Appointment and Promotion Committee to Unqualified Rank, 1990-1993 Member, Executive Committee, Center for Cardiopulmonary Biology, 1991-present Member, University Public Relations Task Force on Animal Research, 1992-1994 Member, Laboratory Animal Facility Advisory Committee, 1989-1993 Member, Advisory Committee, Center for Research in Special Environments - 1993-present Faculty Council Representative, Department of Medicine, 1994-1996 Member, Biomedical Research Committee, Faculty Council, 1994-1996 Member, Cardiology Fellowship Committee, 1994-present Member, Human Subjects Institutional Review Board, State University of New York at Buffalo,1995-1997 Member, Buswell Fellowship Committee, 1995-present Member, PET Operations Committee, 1996-present Chairman, Ad hoc University Investigation Committee for Noncompliance with DHHS/OPRR Regulations, 1996 Member, Graduate Educational Policies in Biomedical Sciences Committee of the Faculty Council, 1996-present Member, Facilities Planning and Budget Committee of the Faculty Council, 1990-1994, 1996-1998 Member, Faculty Council ad hoc Committee on Professional Harassment, 1996 - 1997 Member, Hubnet Advisory Committee, 1996 - present Member, Ad Hoc Committee for Engineering Research Themes, 1996-1997 Vice Chairman, Human Subjects Institutional Review Board, State University of New York at Buffalo, 1997 - present
Erie County Medical Center: Member, Pharmacy and Therapeutics Committee, 1987-1989 Member, Subcommittee on Drug Utilization and Evaluation, l987-1993 Member, Library Committee, 1989-present
Veterans Administration Medical Center Member, Animal Study Subcommittee, 1993-1997 Member, Research and Development Product Support Group, 1995-1996
American Heart Association: National: Member, Program Committee of the Council on Circulation, l985-1988, 1990 Member, Executive Committee, Council on Circulation, AHA National Center,1992-present Member, Budget Committee, Council on Circulation, AHA National Center, 1992-1995 Member, Long Range Planning Committee, Council on Circulation, 1995-1996; Ad hoc Reviewer, Melvin L. Marcus Award, 1993; Associate Editor, Council on Circulation Newsletter, 1994 - 1995; Editor, Council on Circulation Newsletter, 1995-1997; Council on Circulation Representative, AHA Public Affairs Committee, 1995-1996
New York State Affiliate: Chairman, Peer Review Committee, AHA New York State Affiliate, 1987-1988; Member, Peer Review Committee, AHA New York State Affiliate,l985-l986; Member, Affiliate Cabinet, AHA New York State Affiliate, l987-1989; Member, Long Range Planning Committee, AHA New York State Affiliate, 1990 Member, Research Committee, AHA New York State Affiliate, 1987-1992
American College of Cardiology: Member, Computer Applications Committee, 1990-1995; Chairman, Computer Applications Committee Program, 1993 ACC Scientific Sessions; Chapter Councilor, New York State Chapter, 1994-1996
National Institutes ofHealth - NHLBI: Regular Member, Cardiovascular Renal Study Section, 1993 - 1997; 1999 - present; Member, SCOR Site Visit, M. Marcus University of Iowa 1989; Member, SCOR Site Visit, D. Skorton University of Iowa, 1991; Member, Program Project Site Visit, Julien I.E. Hoffman, University of California at San Francisco, 1992; Member, Special Emphasis Panel on Effects of Sex Hormones on Coronary Artery Reactivity, 1993; Member, SCOR Site Visit, Thomas Smith, Harvard Medical School, 1994; Member, SPIR/STTR Cardiovascular Sciences Initial Review Group, 1999
Veterans Administration: Ad hoc Merit Review external reviewer, 1994 - present
KeywordsCOS Keywords:Cardiology, Cardiovascular Diseases, Cardiovascular Physiology, Clinical Medicine, Heart, Molecular Biology.Additional Terms:Cardiovascular Molecular Biology, Coronary Physiology, Myocardial Ischemia Cardiology.MembershipsAmerican College of Cardiology American College of Physicians American Federation for Medical Research American Heart Association American Physiological Society Honors and Awards1983-1988,
Clinical Investigator Award,
National Institutes of Health (NIH)
Previous Positions1989-1995, Associate Professor,
University at Buffalo,
School of Medicine and Biomedical Sciences,
Medicine
1986-1996, Assistant Professor,
University at Buffalo,
Physiology
1983-1989, Assistant Professor,
University at Buffalo,
School of Medicine and Biomedical Sciences,
Medicine
1981-1983, Fellow,
University at Buffalo,
School of Medicine and Biomedical Sciences,
Cardiology
1981-1983, Instructor,
University at Buffalo,
School of Medicine and Biomedical Sciences,
Medicine
1979-1981, Resident,
University of Rochester,
School of Medicine,
Internal Medicine
Funding Received- National Institutes of Health (NIH):
Apoptosis and Contractility in Ischemic Cardiomyopathy,
$1,608,114,
Jan 10, 2000
to Dec 31, 2003.
- Medtronic, Inc.:
Short and Long-term ECG Predictors of Risk for Sudden Cardiac Death in Hibernating Myocardium,
2005
to 2006.
- National Institutes of Health (NIH):
Hibernating Myocardium and Sudden Cardiac Death,
2004
to 2009.
- John R. Oishei Foundation:
Sudden Death in Ischemic Heart Disease,
2003
to 2005.
- Mae Stone Goode Trust:
Physiological, Molecular and Pathological Triggers Responsible for Cardiac Arrhythmogenesis in Viable Chronically Dysfunctional Myocardium,
2003
to 2005.
- Department of Veterans Affairs:
Angiogenesis and Myocardial Perfusion,
2001
to 2005.
- National Institutes of Health (NIH):
Chronic Adaptations to Myocardial Ischemia,
$1,605,28,
1996
to 2001.
Publications- Fallavollita, J.A., B.J. Riegel, G. Suzuki, U. Valeti, and J.M. Canty, Jr. (2005) Mechanism of sudden cardiac death in pigs with viable chronically dysfunctional myocardium and ischemic cardiomyopathy, American Journal of Physiology: Heart and Circulatory Physiology, 289, H2688-H2696
- Iyer, V.S., and J.M. Canty, Jr. (2005) Regional desensitization of beta-adrenergic receptor signaling in swine with chronic hibernating myocardium, Circulation Research, 97, 789-795
- Ovchinnikov, V., G. Suzuki, J.M. Canty, Jr., and J.A. Fallavollita (2005) Blunted functional responses to sympathetic stimulation in hibernating myocardium: Functional evidence for sympathetic dysinnervation, American Journal of Physiology: Heart and Circulatory Physiology, 289, H1719-H1728
- Luisi, A.J., Jr., J.A. Fallavollita, G. Suzuki, R. deKemp, M.S. Haka, S.A. Toorongian (2005) Regional 11-C-hydroxyephedrine retention in hibernating myocardium: Chronic inhomogeneity of sympathetic innervation in the absence of infarction, Journal of Nuclear Medicine, 46, 1368-1374
- Vacanti, V., E. Kong, G. Suzuki, K. Sato, J.M. Canty, Jr., and T-C Lee (2005) Phenotypic changes of adult porcine mesenchymal stem cells induced by prolonged passaging in culture, Journal of Cellular Physiology, 205, 194-201
- Suzuki, G., T-C. Lee, J.A. Fallavollita, and J.M. Canty, Jr. (2005) Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle, Circulation Research, 96, 767-775
- Canty, J.M., Jr., and J.A. Fallavollita (2004) Hibernating myocardium, Journal of Nuclear Cardiology, 12, 104-119
- Thijssen, V.L.J.L., M. Borgers, M.-H. Lenders, F.C. Ramaekers, G. Suzuki, B. Palka, J.A. Fallavollita, S.A. Thomas, J.M. Canty, Jr. (2004) Temporal and spatial variations in structural protein expression during the progression from stunned to hibernating myocardium, Circulation, 110, 3313-3321
- Canty, J.M., Jr., G. Suzuki, M.D. Banas, F. Verheyen, M. Borgers, and J.A. Fallavollita (2004) Hibernating myocardium: Chronically adapted to ischemia but vulnerable to sudden death, Circulation Research, 94, 1142-1149
- Fallavollita, J.A., U. Valeti, S. Oza, and J.M. Canty, Jr. (2004) Spatial heterogeneity of endocardial voltage amplitude in viable, chronically dysfunctional myocardium, Basic Res. Cardiol., 99, 212-222
- Canty, J.M., Jr., and J.A. Fallavollita (2003) Sympathetic nerves and myocyte necrosis: More than meets the eye, Circulation Research, 93, 796-798
- Fallavollita, J.A., B.J. Malm, and J.M. Canty, Jr. (2003) Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function and oxygen consumption at rest, Circulation Research, 92, 48-55
- Thomas, S.A., J.A. Fallavollita, M. Borgers, and J.M. Canty, Jr. (2002) Dissociation of regional adaptations to ischemia and global myolysis in an accelerated swine model of chronic hibernating myocardium, Circulation Research, 91, 970-977
- Malm, B.J., G. Suzuki, J.M. Canty, Jr., and J.A. Fallavollita (2002) Variability of contractile reserve in hibernating myocardium: Dependence on the method of inotropic stimulation, Cardiovascular Research, 56, 422-432
- Fallavollita, J.A., M. Logue, and J.M. Canty, Jr. (2002) Coronary patency and its relation to contractile reserve in hibernating myocardium, Cardiovascular Research, 55, 131-140
- Canty, J.M., Jr., and G. Suzuki (2002) Heterogeneity of apoptosis and myolysis in coronary microembolization: A competition between programmed cell death and programmed cell survival, European Heart Journal, 23, 838-840
- Canty, J.M., Jr., and T.C. Lee (2002) Troponin I proteolysis and myocardial stunning: Now you see it - now you don't, Journal of Mollecular and Cellular Cardiology, 34, 375-377
- Fallavollita, J.A., and J.M. Canty, Jr. (2002) Ischemic cardiomyopathy in pigs with 2-vessel occlusion and viable, chronically dysfunctional myocardium, American Journal of Physiology: Heart and Circulatory Physiology, 282, H1370-H1379
- Feng, J., B. J. Schaus, J. A. Fallavollita, T-C Lee, J. M. Canty, Jr, Preload induces troponin I degradation independently of myocardial ischemia, Circulation, 103, 2035-2037, 2001
- Fallavollita, J.A., M. Logue, J.M. Canty, Jr., Stability of hibernating myocardium in pigs with a chronic LAD stenosis: Absence of progressive fibrosis in the setting of stable reductions in flow, function and coronary flow reserve, Journal of the American College of Cardiology, 37, 1989-1995, 2001
- Dube, S, J.M. Canty, Jr., Shear stress-induced vasodilation in porcine coronary conduit arteries is independent of nitric oxide release, American Journal of Physiology, 280, H2581-H2590, 2001
- Fallavollita, J.A., H. Lim, and J.M. Canty, Jr. (2001) Myocyte apoptosis and reduced SR gene expression precede the transition from chronically stunned to hibernating myocardium, Journal of Molecular and Cellular Cardiology, 33, 1937-1944
- Canty, J.M., Jr., and J.A. Fallavollita (2001) Lessons from experimental models of hibernating myocardium, Coronary Artery Disease, 12, 371-380
- Kositprapa, C., B. Zhang, S. Berger, J. M. Canty, Jr., T-C Lee, Calpain-mediated proteolytic cleavage of troponin I induced by hypoxia or metabolic inhibition in cultured neonatal cardiomyocytes, Molecular and Cellular Biochemistry, 214, 47-55, 2000
- Fallavollita, J.A., C. Trojan, J.M. Canty, Jr., Transmural distribution of FDG uptake following short-term hibernation, American Journal of Physiology, 279, H102-H109, 2000
- Canty J.M. Jr, J.A. Fallavollita, Chronic hibernation and chronic stunning: A continuum, Journal of Nuclear Cardiology, 7, 509-527, 2000
- Lim H, Fallavollita JA, Hard R, Kerr CW, Canty JM Jr, Profound apoptosis-mediated regional myocyte loss and compensatory hypertrophy in pigs with hibernating myocardium, Circulation, 100(23), 2380-6, 1999
 - Fallavollita, J.A., B.J. Perry, J.M. Canty, Jr., 18F-2-deoxyglucose deposition and regional flow in pigs with chronically dysfunctional myocardium: Evidence for transmural variations in chronic hibernating myocardium, Circulation, 95, 1900-1909, 1997
Profile DetailsIndividual Expertise profile of John M. Canty, Copyright John M. Canty. © COS Expertise TM, 2010, ProQuest LLC All rights reserved. |