Dr. Corinne C. Aragaki

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University of Texas Health Science Center at Houston
School of Public Health
Human Genetics Center
Epidemiology and Biostatistics
Assistant ProfessorAppointed: 2001
Epidemiologic Perspectives & Innovations
Biomed Central journal
Appointed: 2005
University of Texas Southwestern Medical Center at Dallas
Adjunct Assistant ProfessorAppointed: 2003

Mailing Address

University of Texas School of Public Health
1200 Herman Pressler Drive
Suite RAS-E511
Houston, Texas 77030
United States

Contact Information

Phone: (713) 500-9915
Fax: (713) 500-0900
Corinne.C.Aragaki@uth.tmc.edu

Qualifications

Ph.D., University of California, Los Angeles, Epidemiology, 1997.
M.S.P.H., University of California, Los Angeles, Epidemiology, 1995.
B.S., University of California, Irvine, Mathematics, 1985.
B.S., University of California, Irvine, Biological Sciences, 1985.

Expertise and Research Interests

Gene-environment interaction estimation; Gene discovery in infectious disease epidemiology; Higher order genetic interaction methods; Use of microarrays in genetic/molecular/genomic epidemiology studies; Archetypal analysis in nutritional epidemiology; Population-based family study designs; Epidemiologic methodology for gene-environment interaction estimation.

Other Expertise

2007 Invited Faculty member, Breakfast with the Experts Roundtables, Society for Epidemiologic Research
2007 Spotlight Session Chair, Society for Epidemiologic Research, Assessing genetic susceptibility: how hard can it be?
2007 Member, Epidemiology Faculty Retreat Planning Committee, Epidemiology Division, UT-Houston School of Public Health
2006- Member, Committee for the Status of Women, UT Health Science Center
2005- Member, Faculty Search Committee, Epidemiology Division, UT-Houston School of Public Health
2004-2007 Member, Admissions Committee, Epidemiology Division, UT-Houston School of Public Health
2002- Member, Texas Cancer Council, Cancer Data Workgroup
2002-2004 Faculty Affairs Committee Dallas regional campus member, UT-Houston School of Public Health
2002-2003 Member, UT School of Public Health, Dallas regional campus biostatistics faculty search committee
2001-2003 Member, UT-Southwestern and UT-Dallas biostatistics faculty search committees

Future Research

1. Analytic strategies for integration of biological pathways to identify complex higher order interaction in infectious disease epidemiology
A. Effects Estimation to Identify Immune Pathway SNP Patterns Associated with Severe Sepsis After Burn Trauma
B. Effects Estimation to Identify Immune Pathway SNP Patterns Associated with H. pylori infection in Hispanic Children (PASITOS cohort)
2. Use of microarrays in genetic/molecular/genomic epidemiology studies:
A. Expression arrays in use for gene-environment interaction estimation,
B.SNP chips for linkage/linkage disequilibrium/LOH/combined analyses,
C. Genotyping chips for molecular epidemiology.
3. Archetypal analysis in nutritional epidemiology.

Industrial Relevance

1. Post-genomic, individualized risk assessment

Keywords

COS Keywords:

Arteriosclerosis or Atherosclerosis, Biometry, Biostatistics, Cancer or Carcinogenesis, Cancer Prevention, Cardiovascular Diseases, Chemical Carcinogenesis, Computational Biology, Epidemiology, Gene Expression, Genetic Markers, Genetic Models, Human Genome, Human Population and Genetics, Medical Genetics, Molecular Epidemiology, Molecular Genetics, Outcomes Research (Medical), Pharmacogenetics, Pharmacokinetics, Phenotype, Proteomics, Public Health, Reaction Kinetics, Research Methodology.

Additional Terms:

Cancer Epidemiology, Cancer Prevention, Chemical Carcinogenesis, Epidemiologic Methods, Gene Expression, Gene-environment Interaction Risk Estimation, Genetic Epidemiology, Human Genetics, Human Genome, Human Population, Infectious Disease Epidemiology, Molecular Epidemiology, Reaction Kinetics, Research Methodology.

Memberships

American Statistical Association
Delta Omega
International Genetic Epidemiology Society
Society for Epidemiologic Research

Honors and Awards

2002, Outstanding Teacher of the Year, School of Public Health, University of Texas Health Science Center at Houston, Dallas Regional Campus
2002, Nominee, President's Award for Mentoring Women, UT Health Science Center
1996, Graduate Student Member, Delta Omega Honor Society, UCLA, Public Health

Previous Positions

2004-2005, Editor-in-Chief, Epidemiologic Perspectives & Innovations, (Biomed Central Journal)
2000-2001, Assistant Professor, University of Texas Health Science Center at Houston, School of Public Health, Dallas Regional Campus, Epidemiology
1997-2000, Postdoctoral Fellow, University of Washington
1997-2000, Postdoctoral Fellow, Fred Hutchinson Cancer Research Center

Patents

Unified Framework for mapping complex traits, Patent Number: Provisional 60/083871, 1998, Fred Hutchinson Cancer Re, United States.

Funding Received

  • NIDDK: H. Pylori Infection in Hispanic Children: Immune Response Pathway SNP Patterns, , 2007 to 2009.
  • NIGMS: Pathophysiological Biochemical Changes Of Thermal Injury, , 2005 to 2010.
  • NIDDK: H.pylori Infection in Children on the US-Mexico Border, , 2004 to 2007.

Publications

  • Jain MK*, Aragaki CC, Fischbach LA, Gibson S, Arora R, May L, Vardhineni K, Lee WM. (2007) Hepatitis C Is Associated with Type 2 Diabetes Mellitus in HIV Infected Persons Without Traditional Risk Factors, HIV Medicine, In Press
  • Cardenas VM, Dominguez DC, Puentes FA*, Aragaki CC, Goodman KJ, Graham DY, Fukuda Y (2007) Evaluation of a Novel Stool Native Catalase Antigen Test for Helicobacter pylori Infection in Asymptomatic North American Children, Journal of Pediatric Gastroenterology and Nutrition, In Press
  • Barber RC, Aragaki CC, Chang E, Purdue G, Hunt JL, Arnold BF, Horton JE. (2007) CD14-159 C-allele is associated with increased risk for mortality after burn injury, Shock
  • Du XL, Fang S*, Coker AL, Sanderson M, Aragaki C, Cormier JN, Xing Y, Gor BJ, Chan W (2006) Racial Disparity and Socioeconomic Status in Association with Survival in Older Men with Local/Regional Stage Prostate Cancer: Findings from a Large Community-Based Cohort, Cancer
  • Silva R*, Thomas M, Caetano R, Aragaki C. (2006) Preventing low birth weight in Illinois: Outcomes of the Family Case Management Program, Maternal and Child Health Journal
  • Barber RC, Chang E, Arnoldo BD, Purdue GF, Hunt JL, Horton JW, Aragaki CC (2006) Innate Immunity SNPs are Associated with Risk for Severe Sepsis after Burn Injury, Clinical Medicine And Research
  • Barber RC, Chang LY, Purdue GF, Hunt JL, Arnoldo BD, Aragaki CC, Horton JW (2006) Detecting genetic predisposition for complicated clinical outcomes after burn injury, Burns
  • Gupta A*, Schecter A, Aragaki CC, Roehrborn CG (2006) Dioxin exposure and benign prostatic hyperplasia, Journal of Occupational & Environmental Medicine
  • Gupta A*, Ketchum N, Roehrborn CG, Schecter A, Aragaki CC, Michalek JE (2006) Serum dioxin, testosterone and subsequent risk of benign prostatic hyperplasia: a prospective cohort study of Air Force veterans, Environmental Health Perspectives
  • Gupta A, Aragaki C, Gotoh M, Masumori N, Ohshima S, Tsukamoto T, Roehrborn CG (Feb 2005) Relationship between prostate specific antigen and indexes of prostate volume in Japanese men., The Journal of Urology, 173 (2), 503-6 Abstract
  • Goodman KJ, O'Rourke K, Day RS, Wang C*, NurgalievaZ, Phillips CV, Aragaki C, Campos A, de la Rosa MJ (2005) Dynamics of Helicobacter pylori infection in a US-Mexico cohort during the first two years of life, International Journal of Epidemiology
  • Gupta A, Roehrborn C, Aragaki C, Re: complexed prostate specific antigen improves specificity for prostate cancer detection: results of a prospective multicenter clinical trial, The Journal of Urology, 171(6 Pt 1), 2384-5; author reply, 2004 Abstract
  • Coyle YM, Aragaki CC, Hynan LS, Gruchalla RS, Khan DA, Effectiveness of Acute Asthma Care Among Inner-city Adults, Archives of Internal Medicine, 163(13), 1591-6, 2003 Abstract
  • Fischbach LA, Goodman KJ, Feldman M, Aragaki C, Sources of variation of Helicobacter pylori treatment success in adults worldwide: a meta-analysis, International Journal of Epidemiology, 31(1), 128-39, February 2002 Abstract
  • Aragaki C, Spreadsheet that shows P-value functions, Epidemiology, 12(5), 588, September 2001 Abstract
  • Hsu L, Zhao LP, Aragaki C, A note on a conditional-likelihood approach for family-based association studies of candidate genes, Human Heredity, 50(3), 194-200, 2000 Abstract
  • Zhao LP, Quiaoit F, Aragaki C, Hsu L, An efficient, robust and unified method for mapping complex traits (III): combined linkage/linkage-disequilibrium analysis, American Journal of Medical Genetics, 84(5), 433-53, June 1999 Abstract
  • Aragaki C, Quiaoit F, Hsu L, Zhao LP, Mapping alcoholism genes using linkage/linkage disequilibrium analysis, Genetic Epidemiology, 17 Suppl 1, S43-8, 1999 Abstract
  • Hsu L, Aragaki C, Quiaoit F, Wang X, Xu X, Zhao LP, A genome-wide scan for a simulated data set using two newly developed methods, Genetic Epidemiology, 17 Suppl 1, S621-6, 1999 Abstract
  • Zhao LP, Aragaki C, Hsu L, Potter J, Elston R, Malone KE, Daling JR, Prentice R, Integrated Designs for Gene Discovery and Characterization, JNCI Monographs, 26, 71-80, 1999
  • Zhao LP, Quiaoit F, Aragaki C, Hsu L, An efficient, robust, and unified method for mapping complex traits (II): multipoint linkage analysis, American Journal of Medical Genetics, 79(1), 48-61, August 1998 Abstract
  • Zhao LP, Aragaki C, Hsu L, Quiaoit F, Mapping of complex traits by single-nucleotide polymorphisms, American Journal of Human Genetics, 63(1), 225-40, July 1998 Abstract
  • Zhao LP, Quiaoit F, Hsu L, Aragaki C, Efficient, robust, and unified method for mapping complex traits (I): two-point linkage analysis, American Journal of Medical Genetics, 77(5), 366-83, June 1998 Abstract
  • Zarbl H, Aragaki C, Zhao LP, An efficient protocol for rare mutation genotyping in a large population, Genetic Testing, 2(4), 315-21, 1998 Abstract
  • Aragaki CC, Greenland S, Probst-Hensch N, Haile RW, Hierarchical modeling of gene-environment interactions: estimating NAT2 genotype-specific dietary effects on adenomatous polyps, Cancer Epidemiology, Biomarkers and Prevention, 6(5), 307-14, May 1997 Abstract
  • de Arruda ME, Aragaki C, Gagliardi F, Haile RW, A seroprevalence and descriptive epidemiological study of malaria among Indian tribes of the Amazon basin of Brazil, Annals of Tropical Medicine and Parasitology, 90(2), 135-43, April 1996 Abstract
  • Haile RW, Cortessis VK, Millikan R, Ingles S, Aragaki CC, Richardson L, Thompson WD, Paganini-Hill A, Sparkes RS, A linkage analysis of D17S74 (CMM86) in thirty-five families with premenopausal bilateral breast cancer, Cancer Research, 53(2), 212-4, January 1993 Abstract
  • Ursin G, Aragaki CC, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW, Oral contraceptives and premenopausal bilateral breast cancer: a case-control study, Epidemiology, 3(5), 414-9, September 1992 Abstract
  • Aragaki C, Barber RC, Purdue G, Complex Higher Order Interaction Combined Effects Estimation Identifies Immune Pathway SNP Patterns Associated with Severe Sepsis After Burn Trauma, Epidemiologic Perspectives & Innovations, Submitted

Profile Details

Last Verified: 9/5/2007

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