Charles Asbury

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University of Washington
School of Medicine
Physiology and Biophysics
Professional Headshot of Charles Asbury

Mailing Address

Box 357290
Seattle, Washington 98195
United States

Contact Information

Phone: (206) 543-7808
casbury@u.washington.edu
http://depts.washington.edu/pbiopage/people_fac_page.php?fac_ID=35

Qualifications

Ph.D., University of Washington, Bioengineering, 1999.
M.S., Tulane University, Biomedical Engineering, 1993.
B.S., Cornell University, Mechanical Engineering, 1991.

Expertise and Research Interests

Roles of motor proteins and microtubule-associated proteins in kinetochore function
Molecular motors, cytoskeletal filaments, mechanism of kinesin motility
Biomolecular mechanics
Biological applications of optical forces, single molecule measurement techniques
Optical microscopy, fluorescence microscopy, confocal microscopy

Keywords

COS Keywords:

Biophysics, Confocal Microscopy, Microscopy, Mitosis.

Additional Terms:

Biophysics, Kinetochores, Mitosis, Molecular Motors.

Memberships

American Association for the Advancement of Science
American Society for Cell Biology
Biophysical Society

Honors and Awards

2006-2009, Searle Scholar Award, Kinship Foundation, Searle Scholars Program
2006-2011, Packard Fellowship for Science and Engineering, Packard Foundation
2005-2006, Marian E. Smith Junior Faculty Research Award, University of Washington

Publications

  • Asbury CL, Gestaut DR, Powers AF, Franck AD, Davis TN (2006) The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement, Proc Natl Acad Sci USA, 103 (26), 9873-9878
  • Asbury, CL (2005) Kinesin: World's Tiniest Biped, Curr Opin Cell Biol, 17, 89-97
  • Asbury CL, Block SM (2004) Protein Machines In Meyers RA (eds), Encyclopedia of Molecular Cell Biology and Molecular Medicine, Weinheim, Germany, Wiley-VCH, 575-600 pages (bookchapter)
  • Block SM, Asbury CL, Shaevitz JW, Lang MJ (2003) Probing the Kinesin Reaction Cycle with a Two-Dimensional Optical Force Clamp, Proc Natl Acad Sci USA, 100 (5), 2351-2356
  • Asbury CL, Fehr AN, Block SM (2003) Kinesin Moves by an Asymmetric Hand-over-hand Mechanism, Science, 302, 2130-2134
  • Lang MJ, Asbury CL (2002) An Automated Two-Dimensional Optical Force Clamp for Single Molecule Studies, Biophys J, 83, 491-501
  • Franck AD, Powers AF, Gestaut DR, Gonen T, Davis TN, Asbury CL, Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis, Nature Cell Biology, In Press

Profile Details

Last Updated: 6/18/2007

COS Expertise ID #1174021
Reference this profile directly: http://myprofile.cos.com/casbury