Dr. William A. Catterall

powered by
COS Expertise®
University of Washington
School of Medicine
Pharmacology
ChairAppointed: 1981
University of Washington
School of Medicine
Pharmacology
ProfessorAppointed: 1981

Mailing Address

Box 357280
E401 Health Science Building
Seattle, Washington 98195-7280
United States

Contact Information

Phone: (206) 543-1925
Fax: (206) 543-3822
wcatt@u.washington.edu

Qualifications

Ph.D., Johns Hopkins University, School of Medicine, 1972.

Expertise and Research Interests

The Molecular Basis of Electrical Excitability:

Electrical impulses generated by nerve, skeletal muscle, and heart muscle cells play an essential role in coordination of most physiological functions and in learning and memory in the central nervous system. Research in this laboratory is focused on understanding the molecular basis of electrical excitability, the regulation of electrical excitability by physiological stimuli, and the mechanism of action of neurotoxins and drugs which alter electrical excitability. Neurotoxins and drugs have been used asspecific molecular probes to identify, purify, and characterize voltage-sensitive sodium and calcium channels from mammalian brain and skeletal muscle. The function of these purified ion channels has been restored by incorporation into phospholipid bilayer membranes and this experimental system has been used to analyze the relationship between channel structure and function on the molecular level.

Cloned DNA probes which encode the structure of these ion channels, site-directed mutagenesis and functional expression, and site-directed antibodies which recognize specific peptide segments are being used to probe the molecular mechanisms of ion channelfunction and to examine the mechanisms of regulation of biosynthesis, assembly, and localization of ion channels during neural development in vivo and in cell culture. Specific protein segments which form the voltage sensors and inactivation gate of thesodium channel have been defined and sites of phosphorylation by specific protein kinases which modulate sodium and calcium channel function have been identified. Regulation of ion channel properties by physiological and hormonal stimuli is of great interest as a potential mechanism of modulation of information processing, learning, and memory in the central nervous system.

Clinically important drugs, including local anesthetics, antiarrhythmics, antiepileptics, and calcium antagonists alter the properties of voltage-sensitive ion channels. We are currentlyinvestigating the sites and mechanisms by which these drugs alter the properties of ion channels, taking advantage of cultured cell systems, specific antibodies and neurotoxins, purified channel preparations, and cloned cDNAs to attempt to define the mechanism of drug action at the molecular level and identify common themes which may be important in development of new therapeutic agents. Recent work has led to the identification of the receptor sites for the calcium antagonist drugs on calcium channels and the receptor sites for local anesthetic drugs and multiple neurotoxins on sodium channels.

Keywords

COS Keywords:

Biosynthesis, Brain, Cardiovascular Biology, Cell Biology, Central Nervous System, Human Learning and Memory, Ion Channels, Membrane Transport, Molecular Biology, Musculoskeletal System, Nervous System, Neurobiology, Pharmacology, Physiology, Receptors, Vascular Biology.

Additional Terms:

Calcium in the Regulation of Tissue, Cardiac Biology, Cardiac Disease, Cardiovascular Biology, Cell Biology, Cell Function, Ion Channels, Membrane Transport, Molecular Biology, Muscle, Nervous System, Neurobiology, Physiology, Vascular Biology.

Publications

  • Ratcliffe CF, Westenbroek RE, Curtis R, Catterall WA, Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain, Journal of Cell Biology, 154(2), 427-34, 2001 Abstract
  • Zhong H, Li B, Scheuer T, Catterall WA, Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2 channel, Proceedings of the National Academy of Sciences (USA), 98(8), 4705-9, 2001 Abstract
  • Herlitze S, Zhong H, Scheuer T, Catterall WA, Allosteric modulation of Ca2 channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits, Proceedings of the National Academy of Sciences (USA), 98(8), 4699-704, 2001 Abstract
  • Catterall WA, A 3D view of sodium channels, Nature, 409(6823), 988-9 991, 2001 Abstract
  • Brown AM, Westenbroek RE, Catterall WA, Ransom BR, Axonal L-type Ca2 channels and anoxic injury in rat CNS white matter, Journal of Neurophysiology, 85(2), 900-11, February 2001 Abstract
  • Yarov-Yarovoy V, Brown J, Sharp EM, Clare JJ, Scheuer T, Catterall WA, Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na( ) channel alpha subunit, Journal of Biological Chemistry, 276(1), 20-7, 2001 Abstract
  • Cantrell, A.R. and Catterall, W.A., Neuromodulation of Na+ channels: an unexpected form of cellular plasticity, Nature Reviews. Neuroscience, 2, 397-407, 2001
  • Cestele, S., Scheuer, T., Mantegazza, M., Rochat, H. and Catterall, W.A., Neutralization of Gating Charges in Domain II of the Sodium Channel alpha Subunit Enhances Voltage-Sensor Trapping by a beta-Scorpion Toxin, Journal of General Physiology, 118, 291-302, 2001
  • Hockerman GH, Dilmac N, Scheuer T, Catterall WA, Molecular determinants of diltiazem block in domains IIIS6 and IVS6 of L-type Ca(2 ) channels, Molecular Pharmacology, 58(6), 1264-70, December 2000 Abstract
  • McHugh D, Sharp EM, Scheuer T, Catterall WA, Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain, Proceedings of the National Academy of Sciences (USA), 97(22), 12334-8, 2000 Abstract
  • Lee A, Scheuer T, Catterall WA, Ca2 /calmodulin-dependent facilitation and inactivation of P/Q-type Ca2 channels, Journal of Neuroscience, 20(18), 6830-8, 2000 Abstract
  • Cestele S, Catterall WA, Molecular mechanisms of neurotoxin action on voltage-gated sodium channels, Biochimie, 82(9-10), 883-92, 2000 Abstract
  • Ratcliffe CF, Qu Y, McCormick KA, Tibbs VC, Dixon JE, Scheuer T, Catterall WA, A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta, Nature Neuroscience, 3(5), 437-44, May 2000 Abstract
  • Carter AJ, Grauert M, Pschorn U, Bechtel WD, Bartmann-Lindholm C, Qu Y, Scheuer T, Catterall WA, Weiser T, Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL, Proceedings of the National Academy of Sciences (USA), 97(9), 4944-9, 2000 Abstract
  • Catterall WA, From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels, Neuron, 26(1), 13-25, April 2000 Abstract
  • Ertel EA, Campbell KP, Harpold MM, Hofmann F, Mori Y, Perez-Reyes E, Schwartz A, Snutch TP, Tanabe T, Birnbaumer L, Tsien RW, Catterall WA, Nomenclature of voltage-gated calcium channels, Neuron, 25(3), 533-5, March 2000 Abstract
  • Catterall WA, Structure and regulation of voltage-gated Ca2 channels, Annual Review of Cell and Developmental Biology, 16, 521-55, 2000 Abstract
  • Ertel, E.A., Campbell, K.P., Harpold, M.M., Hofmann, F., Mori, Y., Perez-Reyes, E., Schwartz, A., Snutch, T.P., Tanabe, T., Birnbaumer, L., Tsien, R.W. and Catterall, W.A., Nomenclature of voltage-gated sodium channels, Neuron, 28, 365-368, 2000
  • Weiser T, Qu Y, Catterall WA, Scheuer T, Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits, Molecular Pharmacology, 56(6), 1238-44, December 1999 Abstract
  • McCormick KA, Srinivasan J, White K, Scheuer T, Catterall WA, The extracellular domain of the beta1 subunit is both necessary and sufficient for beta1-like modulation of sodium channel gating, Journal of Biological Chemistry, 274(46), 32638-46, 1999 Abstract
  • Qu Y, Rogers JC, Chen SF, McCormick KA, Scheuer T, Catterall WA, Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits, Journal of Biological Chemistry, 274(46), 32647-54, 1999 Abstract
  • Zhong H, Yokoyama CT, Scheuer T, Catterall WA, Reciprocal regulation of P/Q-type Ca2 channels by SNAP-25, syntaxin and synaptotagmin, Nature Neuroscience, 2(11), 939-41, November 1999 Abstract
  • Cantrell AR, Tibbs VC, Westenbroek RE, Scheuer T, Catterall WA, Dopaminergic modulation of voltage-gated Na current in rat hippocampal neurons requires anchoring of cAMP-dependent protein kinase, The Journal of Neuroscience [computer File], 19(17), RC21, 1999 Abstract
  • Cantrell AR, Scheuer T, Catterall WA, Voltage-dependent neuromodulation of Na+ channels by D1-like dopamine receptors in rat hippocampal neurons., Journal of Neuroscience, 19(13), 5301-10, 1 Jul 1999 Abstract
  • Lee A, Wong ST, Gallagher D, Li B, Storm DR, Scheuer T, Catterall WA, Ca2+/calmodulin binds to and modulates P/Q-type calcium channels [see comments, Nature, 399(6732), 155-9, 13 May 1999 Abstract
  • Eaholtz G, Colvin A, Leonard D, Taylor C, Catterall WA, Block of brain sodium channels by peptide mimetics of the isoleucine, phenylalanine, and methionine \(IFM\) motif from the inactivation gate., Journal of General Physiology, 113(2), 279-94, February 1999 Abstract
  • Rohl CA, Boeckman FA, Baker C, Scheuer T, Catterall WA, Klevit RE, Solution structure of the sodium channel inactivation gate., Biochemistry, 38(3), 855-61, 19 Jan 1999 Abstract
  • Srinivasan J, Schachner M, Catterall WA, Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R., Proceedings of the National Academy of Sciences (USA), 95(26), 15753-7, 22 Dec 1998 Abstract
  • Catterall WA, Structure and function of neuronal Ca2+ channels and their role in neurotransmitter release., Cell Calcium, 24(5-6), 307-23, November 1998 Abstract
  • Westenbroek R E, Hoskins L, Catterall W A, Localization of Ca2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals., Journal of Neuroscience, 18(16), 6319-30, 15 Aug 1998 Abstract
  • Gray P C, Scott J D, Catterall W A, Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins., Current Opinion In Neurobiology, 8(3), 330-4, June 1998 Abstract
  • Gray P C, Johnson B D, Westenbroek R E, Hays L G, Yates J R 3rd, Scheuer T, Catterall W A, Murphy B J, Primary structure and function of an A kinase anchoring protein associated with calcium channels., Neuron, 20(5), 1017-26, May 1998 Abstract
  • Westenbroek R E, Bausch S B, Lin R C, Franck J E, Noebels J L, Catterall W A, Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia., Journal of Neuroscience, 18(7), 2321-34, 1 Apr 1998 Abstract
  • McCormick K A, Isom L L, Ragsdale D, Smith D, Scheuer T, Catterall W A, Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunit., Journal of Biological Chemistry, 273(7), 3954-62, 13 Feb 1998 Abstract
  • McPhee J C, Ragsdale D S, Scheuer T, Catterall W A, A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation., Journal of Biological Chemistry, 273(2), 1121-9, 9 Jan 1998 Abstract
  • Eaholtz G, Zagotta W N, Catterall W A, Kinetic analysis of block of open sodium channels by a peptide containing the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate., Journal of General Physiology, 111(1), 75-82, Jan 1998 Abstract
  • Eaholtz G, Zagotta WN, Catterall WA, Kinetic analysis of block of open sodium channels by a peptide containing the isoleucine, phenylalanine, and methionine \(IFM\) motif from the inactivation gate., Journal of General Physiology, 111(1), 75-82, 1998 Abstract
  • Hockerman G H, Peterson B Z, Sharp E, Tanada T N, Scheuer T, Catterall W A, Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non-L-type Ca2+ channel., Proceedings of the National Academy of Sciences (USA), 94(26), 14906-11, 23 Dec 1997 Abstract
  • Kim D K, Catterall W A, Ca2+-dependent and -independent interactions of the isoforms of the alpha1A subunit of brain Ca2+ channels with presynaptic SNARE proteins., Proceedings of the National Academy of Sciences (USA), 94(26), 14782-6, 23 Dec 1997 Abstract
  • Cantrell A R, Smith R D, Goldin A L, Scheuer T, Catterall W A, Dopaminergic modulation of sodium current in hippocampal neurons via cAMP-dependent phosphorylation of specific sites in the sodium channel alpha subunit., Journal of Neuroscience, 17(19), 7330-8, 1 Oct 1997 Abstract
  • Burton K A, Johnson B D, Hausken Z E, Westenbroek R E, Idzerda R L, Scheuer T, Scott J D, Catterall W A, McKnight G S, Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase., Proceedings of the National Academy of Sciences (USA), 94(20), 11067-72, 30 Sep 1997 Abstract
  • Yokoyama C T, Sheng Z H, Catterall W A, Phosphorylation of the synaptic protein interaction site on N-type calcium channels inhibits interactions with SNARE proteins., Journal of Neuroscience, 17(18), 6929-38, 15 Sep 1997 Abstract
  • Rettig J, Heinemann C, Ashery U, Sheng Z H, Yokoyama C T, Catterall W A, Neher E, Alteration of Ca2+ dependence of neurotransmitter release by disruption of Ca2+ channel/syntaxin interaction., Journal of Neuroscience, 17(17), 6647-56, 1 Sep 1997 Abstract
  • Eubanks J, Srinivasan J, Dinulos M B, Disteche C M, Catterall W A, Structure and chromosomal localization of the beta2 subunit of the human brain sodium channel., Neuroreport, 8(12), 2775-9, 18 Aug 1997 Abstract
  • Ma J Y, Catterall W A, Scheuer T, Persistent sodium currents through brain sodium channels induced by G protein betagamma subunits., Neuron, 19(2), 443-52, August 1997 Abstract
  • Johnson B D, Zheng W, Korach K S, Scheuer T, Catterall W A, Rubanyi G M, Increased expression of the cardiac L-type calcium channel in estrogen receptor-deficient mice., Journal of General Physiology, 110(2), 135-40, August 1997 Abstract
  • Hockerman G H, Johnson B D, Abbott M R, Scheuer T, Catterall W A, Molecular determinants of high affinity phenylalkylamine block of L-type calcium channels in transmembrane segment IIIS6 and the pore region of the alpha1 subunit., Journal of Biological Chemistry, 272(30), 18759-65, 25 Jul 1997 Abstract
  • Peterson B Z, Johnson B D, Hockerman G H, Acheson M, Scheuer T, Catterall W A, Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis., Journal of Biological Chemistry, 272(30), 18752-8, 25 Jul 1997 Abstract
  • Sheng Z H, Yokoyama C T, Catterall W A, Interaction of the synprint site of N-type Ca2+ channels with the C2B domain of synaptotagmin I., Proceedings of the National Academy of Sciences (USA), 94(10), 5405-10, 13 May 1997 Abstract
  • Kellenberger S, West J W, Catterall W A, Scheuer T, Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channels., Journal of General Physiology, 109(5), 607-17, May 1997 Abstract
  • Kellenberger S, West J W, Scheuer T, Catterall W A, Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels., Journal of General Physiology, 109(5), 589-605, May 1997 Abstract
  • Trainer V L, McPhee J C, Boutelet-Bochan H, Baker C, Scheuer T, Babin D, Demoute J P, Guedin D, Catterall W A, High affinity binding of pyrethroids to the alpha subunit of brain sodium channels., Molecular Pharmacology, 51(4), 651-7, April 1997 Abstract
  • Gray P C, Tibbs V C, Catterall W A, Murphy B J, Identification of a 15-kDa cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels., Journal of Biological Chemistry, 272(10), 6297-302, 7 Mar 1997 Abstract
  • Herlitze S, Hockerman G H, Scheuer T, Catterall W A, Molecular determinants of inactivation and G protein modulation in the intracellular loop connecting domains I and II of the calcium channel alpha1A subunit., Proceedings of the National Academy of Sciences (USA), 94(4), 1512-6, 18 Feb 1997 Abstract
  • Johnson B D, Brousal J P, Peterson B Z, Gallombardo P A, Hockerman G H, Lai Y, Scheuer T, Catterall W A, Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase., Journal of Neuroscience, 17(4), 1243-55, 15 Feb 1997 Abstract
  • Catterall W A, Modulation of sodium and calcium channels by protein phosphorylation and G proteins., Advances In Second Messenger and Phosphoprotein Research, 31, 159-81, 1997 Abstract
  • Hockerman G H, Peterson B Z, Johnson B D, Catterall W A, Molecular determinants of drug binding and action on L-type calcium channels., Annual Review of Pharmacology and Toxicology, 37, 361-96, 1997 Abstract
  • Kellenberger S, Scheuer T, Catterall W A, Movement of the Na+ channel inactivation gate during inactivation., Journal of Biological Chemistry, 271(48), 30971-9, 29 Nov 1996 Abstract
  • Murphy B J, Rogers J, Perdichizzi A P, Colvin A A, Catterall W A, cAMP-dependent phosphorylation of two sites in the alpha subunit of the cardiac sodium channel., Journal of Biological Chemistry, 271(46), 28837-43, 15 Nov 1996 Abstract
  • Johnson B D, Hockerman G H, Scheuer T, Catterall W A, Distinct effects of mutations in transmembrane segment IVS6 on block of L-type calcium channels by structurally similar phenylalkylamines., Molecular Pharmacology, 50(5), 1388-400, November 1996 Abstract
  • Qu Y, Rogers J C, Tanada T N, Catterall W A, Scheuer T, Phosphorylation of S1505 in the cardiac Na+ channel inactivation gate is required for modulation by protein kinase C., Journal of General Physiology, 108(5), 375-9, November 1996 Abstract
  • Mochida S, Sheng Z H, Baker C, Kobayashi H, Catterall W A, Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channels., Neuron, 17(4), 781-8, October 1996 Abstract
  • Isom L L, Catterall W A, Na+ channel subunits and Ig domains [letter], Nature, 383(6598), 307-8, 26 Sep 1996 Abstract
  • Ragsdale D S, McPhee J C, Scheuer T, Catterall W A, Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels., Proceedings of the National Academy of Sciences (USA), 93(17), 9270-5, 20 Aug 1996 Abstract
  • Kraus R, Reichl B, Kimball S D, Grabner M, Murphy B J, Catterall W A, Striessnig J, Identification of benz(othi)azepine-binding regions within L-type calcium channel alpha1 subunits., Journal of Biological Chemistry, 271(33), 20113-8, 16 Aug 1996 Abstract
  • De Jongh K S, Murphy B J, Colvin A A, Hell J W, Takahashi M, Catterall W A, Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase., Biochemistry, 35(32), 10392-402, 13 Aug 1996 Abstract
  • Rettig J, Sheng Z H, Kim D K, Hodson C D, Snutch T P, Catterall W A, Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25., Proceedings of the National Academy of Sciences (USA), 93(14), 7363-8, 9 Jul 1996 Abstract
  • Rogers J C, Qu Y, Tanada T N, Scheuer T, Catterall W A, Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit., Journal of Biological Chemistry, 271(27), 15950-62, 5 Jul 1996 Abstract
  • Sakurai T, Westenbroek R E, Rettig J, Hell J, Catterall W A, Biochemical properties and subcellular distribution of the BI and rbA isoforms of alpha 1A subunits of brain calcium channels., Journal of Cell Biology, 134(2), 511-28, July 1996 Abstract
  • Catterall W A, Molecular properties of sodium and calcium channels., Journal of Bioenergetics and Biomembranes, 28(3), 219-30, June 1996 Abstract
  • Catterall W A, Ion channels in plasma membrane signal transduction., Journal of Bioenergetics and Biomembranes, 28(3), 217-8, June 1996 Abstract
  • Trainer V L, Brown G B, Catterall W A, Site of covalent labeling by a photoreactive batrachotoxin derivative near transmembrane segment IS6 of the sodium channel alpha subunit., Journal of Biological Chemistry, 271(19), 11261-7, 10 May 1996 Abstract
  • Cantrell A R, Ma J Y, Scheuer T, Catterall W A, Muscarinic modulation of sodium current by activation of protein kinase C in rat hippocampal neurons., Neuron, 16(5), 1019-26, May 1996 Abstract
  • Hell J W, Westenbroek R E, Breeze L J, Wang K K, Chavkin C, Catterall W A, N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons., Proceedings of the National Academy of Sciences (USA), 93(8), 3362-7, 16 Apr 1996 Abstract
  • Herlitze S, Garcia D E, Mackie K, Hille B, Scheuer T, Catterall W A, Modulation of Ca2+ channels by G-protein beta gamma subunits., Nature, 380(6571), 258-62, 21 Mar 1996 Abstract
  • Peterson B Z, Tanada T N, Catterall W A, Molecular determinants of high affinity dihydropyridine binding in L-type calcium channels., Journal of Biological Chemistry, 271(10), 5293-6, 8 Mar 1996 Abstract
  • Sheng Z H, Rettig J, Cook T, Catterall W A, Calcium-dependent interaction of N-type calcium channels with the synaptic core complex., Nature, 379(6564), 451-4, 1 Feb 1996 Abstract
  • Qu Y, Rogers J, Tanada T, Scheuer T, Catterall W A, Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel., Proceedings of the National Academy of Sciences (USA), 92(25), 11839-43, 5 Dec 1995 Abstract
  • Black J A, Westenbroek R E, Catterall W A, Waxman S G, Type II brain sodium channel expression in non-neuronal cells: embryonic rat osteoblasts., Brain research. Molecular Brain Research, 34(1), 89-98, 1 Dec 1995 Abstract
  • Isom L L, Ragsdale D S, De Jongh K S, Westenbroek R E, Reber B F, Scheuer T, Catterall W A, Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif., Cell, 83(3), 433-42, 3 Nov 1995 Abstract
  • Qu Y, Isom L L, Westenbroek R E, Rogers J C, Tanada T N, McCormick K A, Scheuer T, Catterall W A, Modulation of cardiac Na+ channel expression in Xenopus oocytes by beta 1 subunits., Journal of Biological Chemistry, 270(43), 25696-701, 27 Oct 1995 Abstract
  • Westenbroek R E, Sakurai T, Elliott E M, Hell J W, Starr T V, Snutch T P, Catterall W A, Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channels., Journal of Neuroscience, 15(10), 6403-18, October 1995 Abstract
  • Yokoyama C T, Westenbroek R E, Hell J W, Soong T W, Snutch T P, Catterall W A, Biochemical properties and subcellular distribution of the neuronal class E calcium channel alpha 1 subunit., Journal of Neuroscience, 15(10), 6419-32, October 1995 Abstract
  • Elliott E M, Malouf A T, Catterall W A, Role of calcium channel subtypes in calcium transients in hippocampal CA3 neurons., Journal of Neuroscience, 15(10), 6433-44, October 1995 Abstract
  • Wood M R, De Jongh K S, Catterall W A, Pfenninger K H, Na+ channel changes in the growth cone and developing nerve terminal., Brain research. Developmental Brain Research, 88(2), 194-203, 29 Sep 1995 Abstract
  • Hockerman G H, Johnson B D, Scheuer T, Catterall W A, Molecular determinants of high affinity phenylalkylamine block of L-type calcium channels., Journal of Biological Chemistry, 270(38), 22119-22, 22 Sep 1995 Abstract
  • Sakurai T, Hell J W, Woppmann A, Miljanich G P, Catterall W A, Immunochemical identification and differential phosphorylation of alternatively spliced forms of the alpha 1A subunit of brain calcium channels., Journal of Biological Chemistry, 270(36), 21234-42, 8 Sep 1995 Abstract
  • Thomsen W, Martin-Eauclaire M F, Rochat H, Catterall W A, Reconstitution of high-affinity binding of a beta-scorpion toxin to neurotoxin receptor site 4 on purified sodium channels., Journal of Neurochemistry, 65(3), 1358-64, September 1995 Abstract
  • Peterson B Z, Catterall W A, Calcium binding in the pore of L-type calcium channels modulates high affinity dihydropyridine binding., Journal of Biological Chemistry, 270(31), 18201-4, 4 Aug 1995 Abstract
  • Rotman E I, Murphy B J, Catterall W A, Sites of selective cAMP-dependent phosphorylation of the L-type calcium channel alpha 1 subunit from intact rabbit skeletal muscle myotubes., Journal of Biological Chemistry, 270(27), 16371-7, 7 Jul 1995 Abstract
  • Hell J W, Yokoyama C T, Breeze L J, Chavkin C, Catterall W A, Phosphorylation of presynaptic and postsynaptic calcium channels by cAMP-dependent protein kinase in hippocampal neurons., Embo Journal, 14(13), 3036-44, 3 Jul 1995 Abstract
  • Black J A, Westenbroek R, Minturn J E, Ransom B R, Catterall W A, Waxman S G, Isoform-specific expression of sodium channels in astrocytes in vitro: immunocytochemical observations., Glia, 14(2), 133-44, June 1995 Abstract
  • McPhee J C, Ragsdale D S, Scheuer T, Catterall W A, A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation., Journal of Biological Chemistry, 270(20), 12025-34, 19 May 1995 Abstract
  • Trainer V L, Baden D G, Catterall W A, Detection of marine toxins using reconstituted sodium channels., Journal of AOAC, International, 78(2), 570-3, Spring 1995 Abstract
  • Isom L L, Scheuer T, Brownstein A B, Ragsdale D S, Murphy B J, Catterall W A, Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line., Journal of Biological Chemistry, 270(7), 3306-12, 17 Feb 1995 Abstract
  • Catterall WA, Structure and function of voltage-gated ion channels., Annual Review of Biochemistry, 64, 493-531, 1995 Abstract
  • Hell J W, Westenbroek R E, Elliott E M, Catterall W A, Differential phosphorylation, localization, and function of distinct alpha 1 subunits of neuronal calcium channels. Two size forms for class B, C, and D alpha 1 subunits with different COOH-termini., Annals of The New York Academy of Sciences, 747, 282-93, 15 Dec 1994 Abstract
  • McPhee J C, Ragsdale D S, Scheuer T, Catterall W A, A mutation in segment IVS6 disrupts fast inactivation of sodium channels., Proceedings of the National Academy of Sciences (USA), 91(25), 12346-50, 6 Dec 1994 Abstract
  • Ma J Y, Li M, Catterall W A, Scheuer T, Modulation of brain Na+ channels by a G-protein-coupled pathway., Proceedings of the National Academy of Sciences (USA), 91(25), 12351-5, 6 Dec 1994 Abstract
  • Sheng Z H, Rettig J, Takahashi M, Catterall W A, Identification of a syntaxin-binding site on N-type calcium channels., Neuron, 13(6), 1303-13, December 1994 Abstract
  • Johnson B D, Scheuer T, Catterall W A, Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase., Proceedings of the National Academy of Sciences (USA), 91(24), 11492-6, 22 Nov 1994 Abstract
  • Black J A, Westenbroek R, Ransom B R, Catterall W A, Waxman S G, Type II sodium channels in spinal cord astrocytes in situ: immunocytochemical observations., Glia, 12(3), 219-27, November 1994 Abstract
  • De Jongh K S, Colvin A A, Wang K K, Catterall W A, Differential proteolysis of the full-length form of the L-type calcium channel alpha 1 subunit by calpain., Journal of Neurochemistry, 63(4), 1558-64, October 1994 Abstract
  • Ragsdale D S, McPhee J C, Scheuer T, Catterall W A, Molecular determinants of state-dependent block of Na+ channels by local anesthetics., Science, 265(5179), 1724-8, 16 Sep 1994 Abstract
  • Birnbaumer L, Campbell K P, Catterall W A, Harpold M M, Hofmann F, Horne W A, Mori Y, Schwartz A, Snutch T P, Tanabe T, et al, The naming of voltage-gated calcium channels., Neuron, 13(3), 505-6, September 1994 Abstract
  • Trainer V L, Baden D G, Catterall W A, Identification of peptide components of the brevetoxin receptor site of rat brain sodium channels., Journal of Biological Chemistry, 269(31), 19904-9, 5 Aug 1994 Abstract
  • Catterall W A, Molecular properties of a superfamily of plasma-membrane cation channels., Current Opinion In Cell Biology, 6(4), 607-15, August 1994 Abstract
  • Numann R, Hauschka S D, Catterall W A, Scheuer T, Modulation of skeletal muscle sodium channels in a satellite cell line by protein kinase C., Journal of Neuroscience, 14(7), 4226-36, July 1994 Abstract
  • Patton D E, Isom L L, Catterall W A, Goldin A L, The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits., Journal of Biological Chemistry, 269(26), 17649-55, 1 Jul 1994 Abstract
  • Catterall W A, Molecular mechanisms of inactivation and modulation of sodium channels., Renal Physiology and Biochemistry, 17(3-4), 121-5, Summer 1994 Abstract
  • Isom L L, De Jongh K S, Catterall W A, Auxiliary subunits of voltage-gated ion channels., Neuron, 12(6), 1183-94, June 1994 Abstract
  • Eaholtz G, Scheuer T, Catterall W A, Restoration of inactivation and block of open sodium channels by an inactivation gate peptide., Neuron, 12(5), 1041-8, May 1994 Abstract
  • Qu Y, Rogers J, Tanada T, Scheuer T, Catterall W A, Modulation of cardiac Na+ channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C., Proceedings of the National Academy of Sciences (USA), 91(8), 3289-93, 12 Apr 1994 Abstract
  • Marty I, Robert M, Villaz M, De Jongh K, Lai Y, Catterall W A, Ronjat M, Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle., Proceedings of the National Academy of Sciences (USA), 91(6), 2270-4, 15 Mar 1994 Abstract
  • Hell J W, Appleyard S M, Yokoyama C T, Warner C, Catterall W A, Differential phosphorylation of two size forms of the N-type calcium channel alpha 1 subunit which have different COOH termini., Journal of Biological Chemistry, 269(10), 7390-6, 11 Mar 1994 Abstract
  • Murphy B J, Rossie S, De Jongh K S, Catterall W A, Identification of the sites of selective phosphorylation and dephosphorylation of the rat brain Na+ channel alpha subunit by cAMP-dependent protein kinase and phosphoprotein phosphatases., Journal of Biological Chemistry, 268(36), 27355-62, 25 Dec 1993 Abstract
  • Catterall W A, Structure and function of voltage-gated ion channels., Trends In Neurosciences, 16(12), 500-6, December 1993 Abstract
  • Hell J W, Westenbroek R E, Warner C, Ahlijanian M K, Prystay W, Gilbert M M, Snutch T P, Catterall W A, Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits., Journal of Cell Biology, 123(4), 949-62, November 1993 Abstract
  • Patton D E, West J W, Catterall W A, Goldin A L, A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel., Neuron, 11(5), 967-74, November 1993 Abstract
  • Sculptoreanu A, Rotman E, Takahashi M, Scheuer T, Catterall W A, Voltage-dependent potentiation of the activity of cardiac L-type calcium channel alpha 1 subunits due to phosphorylation by cAMP-dependent protein kinase., Proceedings of the National Academy of Sciences (USA), 90(21), 10135-9, 1 Nov 1993 Abstract
  • Lai Y, Peterson B Z, Catterall W A, Selective dephosphorylation of the subunits of skeletal muscle calcium channels by purified phosphoprotein phosphatases., Journal of Neurochemistry, 61(4), 1333-9, October 1993 Abstract
  • Hell J W, Yokoyama C T, Wong S T, Warner C, Snutch T P, Catterall W A, Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit., Journal of Biological Chemistry, 268(26), 19451-7, 15 Sep 1993 Abstract
  • Li M, West J W, Numann R, Murphy B J, Scheuer T, Catterall W A, Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase., Science, 261(5127), 1439-42, 10 Sep 1993 Abstract
  • Trainer V L, Moreau E, Guedin D, Baden D G, Catterall W A, Neurotoxin binding and allosteric modulation at receptor sites 2 and 5 on purified and reconstituted rat brain sodium channels., Journal of Biological Chemistry, 268(23), 17114-9, 15 Aug 1993 Abstract
  • Sculptoreanu A, Scheuer T, Catterall W A, Voltage-dependent potentiation of L-type Ca2+ channels due to phosphorylation by cAMP-dependent protein kinase., Nature, 364(6434), 240-3, 15 Jul 1993 Abstract
  • Catterall W A, de Jongh K, Rotman E, Hell J, Westenbroek R, Dubel S J, Snutch T P, Molecular properties of calcium channels in skeletal muscle and neurons., Annals of The New York Academy of Sciences, 681, 342-55, 21 Jun 1993 Abstract
  • Ragsdale D S, Numann R, Catterall W A, Scheuer T, Inhibition of Na+ channels by the novel blocker PD85,639., Molecular Pharmacology, 43(6), 949-54, June 1993 Abstract
  • Thomsen W, Hays S J, Hicks J L, Schwarz R D, Catterall W A, Specific binding of the novel Na+ channel blocker PD85,639 to the alpha subunit of rat brain Na+ channels., Molecular Pharmacology, 43(6), 955-64, June 1993 Abstract
  • Westenbroek R E, Hell J W, Warner C, Dubel S J, Snutch T P, Catterall W A, Biochemical properties and subcellular distribution of an N-type calcium channel alpha 1 subunit., Neuron, 9(6), 1099-115, December 1992 Abstract
  • Catterall W, Epstein P N, Ion channels., Diabetologia, 35 Suppl 2, S23-33, December 1992 Abstract
  • Patton D E, West J W, Catterall W A, Goldin A L, Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker., Proceedings of the National Academy of Sciences (USA), 89(22), 10905-9, 15 Nov 1992 Abstract
  • West J W, Patton D E, Scheuer T, Wang Y, Goldin A L, Catterall W A, A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation., Proceedings of the National Academy of Sciences (USA), 89(22), 10910-4, 15 Nov 1992 Abstract
  • Duff H J, Offord J, West J, Catterall W A, Class I and IV antiarrhythmic drugs and cytosolic calcium regulate mRNA encoding the sodium channel alpha subunit in rat cardiac muscle., Molecular Pharmacology, 42(4), 570-4, October 1992 Abstract
  • Catterall W A, Cellular and molecular biology of voltage-gated sodium channels., Physiological Reviews, 72(4 Suppl), S15-48, October 1992 Abstract
  • Gordon D, Moskowitz H, Eitan M, Warner C, Catterall W A, Zlotkin E, Localization of receptor sites for insect-selective toxins on sodium channels by site-directed antibodies., Biochemistry, 31(33), 7622-8, 25 Aug 1992 Abstract
  • Rotman E I, De Jongh K S, Florio V, Lai Y, Catterall W A, Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase., Journal of Biological Chemistry, 267(23), 16100-5, 15 Aug 1992 Abstract
  • Murphy B J, Catterall W A, Phosphorylation of purified rat brain Na+ channel reconstituted into phospholipid vesicles by protein kinase C., Journal of Biological Chemistry, 267(23), 16129-34, 15 Aug 1992 Abstract
  • Dubel S J, Starr T V, Hell J, Ahlijanian M K, Enyeart J J, Catterall W A, Snutch T P, Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel., Proceedings of the National Academy of Sciences (USA), 89(11), 5058-62, 1 Jun 1992 Abstract
  • Westenbroek R E, Noebels J L, Catterall W A, Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain., Journal of Neuroscience, 12(6), 2259-67, June 1992 Abstract
  • Li M, West J W, Lai Y, Scheuer T, Catterall W A, Functional modulation of brain sodium channels by cAMP-dependent phosphorylation., Neuron, 8(6), 1151-9, June 1992 Abstract
  • Catterall W A, Striessnig J, Receptor sites for Ca2+ channel antagonists., Trends In Pharmacological Sciences, 13(6), 256-62, June 1992 Abstract
  • Zuber C, Lackie P M, Catterall W A, Roth J, Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain., Journal of Biological Chemistry, 267(14), 9965-71, 15 May 1992 Abstract
  • Isom L L, De Jongh K S, Patton D E, Reber B F, Offord J, Charbonneau H, Walsh K, Goldin A L, Catterall W A, Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel., Science, 256(5058), 839-42, 8 May 1992 Abstract
  • West J W, Numann R, Murphy B J, Scheuer T, Catterall W A, Phosphorylation of a conserved protein kinase C site is required for modulation of Na+ currents in transfected Chinese hamster ovary cells., Biophysical Journal, 62(1), 31-3, April 1992 Abstract
  • Sculptoreanu A, Morton M, Gartside C L, Hauschka S D, Catterall W A, Scheuer T, Tetrodotoxin-insensitive sodium channels in a cardiac cell line from a transgenic mouse., American Journal of Physiology, 262(3 Pt 1), C724-30, March 1992 Abstract
  • Catterall W A, Trainer V, Baden D G, Molecular properties of the sodium channel: a receptor for multiple neurotoxins., Bulletin De La Societe De Pathologie Exotique, 85(5 Pt 2), 481-5, 1992 Abstract
  • Florio V, Striessnig J, Catterall W A, Purification and reconstitution of skeletal muscle calcium channels., Methods In Enzymology, 207, 529-46, 1992 Abstract
  • West J W, Scheuer T, Maechler L, Catterall W A, Efficient expression of rat brain type IIA Na+ channel alpha subunits in a somatic cell line., Neuron, 8(1), 59-70, January 1992 Abstract
  • Catterall W A, A Nobel Prize for single channel recording [editorial], New Biologist, 4(1), 1-3, January 1992 Abstract
  • De Jongh K S, Warner C, Colvin A A, Catterall W A, Characterization of the two size forms of the alpha 1 subunit of skeletal muscle L-type calcium channels., Proceedings of the National Academy of Sciences (USA), 88(23), 10778-82, 1 Dec 1991 Abstract
  • Striessnig J, Murphy B J, Catterall W A, Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the alpha 1 subunit., Proceedings of the National Academy of Sciences (USA), 88(23), 10769-73, 1 Dec 1991 Abstract
  • Trainer V L, Thomsen W J, Catterall W A, Baden D G, Photoaffinity labeling of the brevetoxin receptor on sodium channels in rat brain synaptosomes., Molecular Pharmacology, 40(6), 988-94, December 1991 Abstract
  • West J W, Numann R, Murphy B J, Scheuer T, Catterall W A, A phosphorylation site in the Na+ channel required for modulation by protein kinase C., Science, 254(5033), 866-8, 8 Nov 1991 Abstract
  • Ragsdale D S, Scheuer T, Catterall W A, Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs., Molecular Pharmacology, 40(5), 756-65, November 1991 Abstract
  • Ahlijanian M K, Striessnig J, Catterall W A, Phosphorylation of an alpha 1-like subunit of an omega-conotoxin-sensitive brain calcium channel by cAMP-dependent protein kinase and protein kinase., Journal of Biological Chemistry, 266(30), 20192-7, 25 Oct 1991 Abstract
  • Nakayama H, Taki M, Striessnig J, Glossmann H, Catterall W A, Kanaoka Y, Identification of 1,4-dihydropyridine binding regions within the alpha 1 subunit of skeletal muscle Ca2+ channels by photoaffinity labeling with diazipine., Proceedings of the National Academy of Sciences (USA), 88(20), 9203-7, 15 Oct 1991 Abstract
  • Numann R, Catterall W A, Scheuer T, Functional modulation of brain sodium channels by protein kinase C phosphorylation., Science, 254(5028), 115-8, 4 Oct 1991 Abstract
  • Catterall W A, Functional subunit structure of voltage-gated calcium channels., Science, 253(5027), 1499-500, 27 Sep 1991 Abstract
  • Catterall W A, Structure and function of voltage-gated sodium and calcium channels., Current Opinion In Neurobiology, 1(1), 5-13, June 1991 Abstract
  • Rock D M, McLean M J, Macdonald R L, Catterall W A, Taylor C P, Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro., Epilepsy Research, 8(3), 197-203, April 1991 Abstract
  • Catterall W A, Excitation-contraction coupling in vertebrate skeletal muscle: a tale of two calcium channels., Cell, 64(5), 871-4, 8 Mar 1991 Abstract
  • Catterall W A, Scheuer T, Thomsen W, Rossie S, Structure and modulation of voltage-gated ion channels., Annals of The New York Academy of Sciences, 625, 174-80, 1991 Abstract
  • Lai Y, Seagar M J, Takahashi M, Catterall W A, Cyclic AMP-dependent phosphorylation of two size forms of alpha 1 subunits of L-type calcium channels in rat skeletal muscle cells., Journal of Biological Chemistry, 265(34), 20839-48, 5 Dec 1990 Abstract
  • Striessnig J, Glossmann H, Catterall W A, Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channels., Proceedings of the National Academy of Sciences (USA), 87(23), 9108-12, December 1990 Abstract
  • Westenbroek R E, Ahlijanian M K, Catterall W A, Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons., Nature, 347(6290), 281-4, 20 Sep 1990 Abstract
  • De Jongh K S, Warner C, Catterall W A, Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene., Journal of Biological Chemistry, 265(25), 14738-41, 5 Sep 1990 Abstract
  • Sutkowski E M, Catterall W A, Beta 1 subunits of sodium channels. Studies with subunit-specific antibodies., Journal of Biological Chemistry, 265(21), 12393-9, 25 Jul 1990 Abstract
  • Ahlijanian M K, Westenbroek R E, Catterall W A, Subunit structure and localization of dihydropyridine-sensitive calcium channels in mammalian brain, spinal cord, and retina., Neuron, 4(6), 819-32, June 1990 Abstract
  • Tejedor F J, Catterall W A, Photoaffinity labeling of the receptor site for alpha-scorpion toxins on purified and reconstituted sodium channels by a new toxin derivative., Cellular and Molecular Neurobiology, 10(2), 257-65, June 1990 Abstract
  • Scheuer T, Auld V J, Boyd S, Offord J, Dunn R, Catterall W A, Functional properties of rat brain sodium channels expressed in a somatic cell line., Science, 247(4944), 854-8, 16 Feb 1990 Abstract
  • Catterall W A, Nunoki K, Lai Y, De Jongh K, Thomsen W, Rossie S, Structure and modulation of voltage-sensitive sodium and calcium channels., Advances In Second Messenger and Phosphoprotein Research, 24, 30-5, 1990 Abstract
  • Auld V J, Goldin A L, Krafte D S, Catterall W A, Lester H A, Davidson N, Dunn R J, A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel., Proceedings of the National Academy of Sciences (USA), 87(1), 323-7, January 1990 Abstract
  • Thomsen W J, Catterall W A, Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology., Proceedings of the National Academy of Sciences (USA), 86(24), 10161-5, December 1989 Abstract
  • Westenbroek R E, Merrick D K, Catterall W A, Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons., Neuron, 3(6), 695-704, December 1989 Abstract
  • De Jongh K S, Merrick D K, Catterall W A, Subunits of purified calcium channels: a 212-kDa form of alpha 1 and partial amino acid sequence of a phosphorylation site of an independent beta subunit., Proceedings of the National Academy of Sciences (USA), 86(21), 8585-9, November 1989 Abstract
  • Vassilev P, Scheuer T, Catterall W A, Inhibition of inactivation of single sodium channels by a site-directed antibody., Proceedings of the National Academy of Sciences (USA), 86(20), 8147-51, October 1989 Abstract
  • Nunoki K, Florio V, Catterall W A, Activation of purified calcium channels by stoichiometric protein phosphorylation., Proceedings of the National Academy of Sciences (USA), 86(17), 6816-20, September 1989 Abstract
  • Rossie S, Catterall W A, Phosphorylation of the alpha subunit of rat brain sodium channels by cAMP-dependent protein kinase at a new site containing Ser686 and Ser687., Journal of Biological Chemistry, 264(24), 14220-4, 25 Aug 1989 Abstract
  • Scheinman R I, Auld V J, Goldin A L, Davidson N, Dunn R J, Catterall W A, Developmental regulation of sodium channel expression in the rat forebrain., Journal of Biological Chemistry, 264(18), 10660-6, 25 Jun 1989 Abstract
  • Offord J, Catterall W A, Electrical activity, cAMP, and cytosolic calcium regulate mRNA encoding sodium channel alpha subunits in rat muscle cells., Neuron, 2(5), 1447-52, May 1989 Abstract
  • Catterall W A, Seagar M J, Takahashi M, Nunoki K, Molecular properties of dihydropyridine-sensitive calcium channels., Annals of The New York Academy of Sciences, 560, 1-14, 1989 Abstract
  • Catterall W A, Seagar M J, Takahashi M, Nunoki K, Molecular properties of voltage-sensitive calcium channels., Advances In Experimental Medicine and Biology, 255, 101-9, 1989 Abstract
  • Wollner D A, Catterall W A, Antigenic differences among the voltage-sensitive sodium channels in the peripheral and central nervous systems and skeletal muscle., Brain Research, 331(1), 145-9, 1 Apr 1985 Abstract
  • Sherman S J, Catterall W A, The developmental regulation of TTX-sensitive sodium channels in rat skeletal muscle in vivo and in vitro., Society of General Physiologists Series, 39, 237-63, 1985 Abstract
  • Hartshorne R P, Keller B U, Talvenheimo J A, Catterall W A, Montal M, Functional reconstitution of the purified brain sodium channel in planar lipid bilayers., Proceedings of the National Academy of Sciences (USA), 82(1), 240-4, January 1985 Abstract
  • Sheng ZH, Yokoyama CT, Catterall WA. Interaction of the synprint site of N-type Ca2+ channels with the C2B domain of synaptotagmin I. Proc Natl Acad Sci USA 94 (10): 5405-5410 (May 13 1997)
  • Kellenberger S, West JW, Catterall WA, Scheuer T. Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channels. J Gen Physiol 109 (5): 607-617 (May 1997)
  • Kellenberger S, West JW, Scheuer T, Catterall WA. Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels. J Gen Physiol 109 (5): 589-605 (May 1997)
  • Trainer VL, McPhee JC, Boutelet-Bochan H, Baker C, Scheuer T, Babin D, Demoute JP, Guedin D, Catterall WA. High affinity binding of pyrethroids to the alpha subunit of brain sodium channels. Mol Pharmacol 51 (4): 651-657 (Apr 1997)
  • Gray PC, Tibbs VC, Catterall WA, Murphy B. Identification of a 15-kDa cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels. J Biol Chem 272 (10): 6297-6302 (Mar 7 1997)
  • Herlitze S, Hockerman GH, Scheuer T, Catterall WA. Molecular determinants of inactivation and G protein modulation in the intracellular loop connecting domains I and II of the calcium channel alpha1A subunit. Proc Natl Acad Sci USA 94 (4): 1512-1516 (Feb18 1997)
  • Johnson BD, Brousal JP, Peterson BZ, Gallombardo PA, Hockerman GH, Lai Y, Scheuer T, Catterall WA. Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase. J Neurosci 17 (4): 1243-1255 (Feb 15 1997)
  • Baruscotti M, Westenbroek R, Catterall WA, DiFrancesco D, Robinson RB. The newborn rabbit sino-atrial node expresses a neuronal type I-like Na+ channel. J Physiol (Lond) 498 ( Pt 3): 641-648 (Feb 1 1997)
  • Hockerman GH, Peterson BZ, Johnson BD, Catterall WA. Molecular determinants of drug binding and action on L-type calcium channels. Annu Rev Pharmacol Toxicol 37: 361-396 (1997)

Profile Details

Last Updated: 10/17/2001

COS Expertise ID #307358
Reference this profile directly: http://myprofile.cos.com/catteraw58