Dr. Christine V. F. Carrington | |
University of the West Indies St. Augustine Campus Senior LecturerAppointed: 2005 University of the West Indies St. Augustine Campus Deputy Dean for Graduate Studies and ResearchAppointed: 2007 | |
QualificationsPh.D., University of London, Molecular Virology, 1994. B.Sc., King's College London, Biotechnology, 1990. Expertise and Research InterestsAreas of expertise: Molecular biology, molecular genetics, virology, RNA viruses, virus evolution and phylogenetics.
Current research interests: *Molecular genetics, virology and viral evolution *Evolutionary and ecological factors involved in the emergence and spread of vector-borne viral zoonoses (esp. dengue, other arboviruses and viruses vectored by bats). *Viral and host genetic factors that determine disease severity in arboviral infections *Emerging viral infectious diseases KeywordsCOS Keywords:Biodiversity, Biological Sciences, Chemical Sciences, Epidemiology, Evolutionary Biology, Health and Medicine, Immunogenetics, Immunology, Infectious Diseases or Agents, Molecular Biology, Molecular Epidemiology, Molecular Genetics, Molecular Virology, Phylogenetics, Tropical Biology, Viral Infections, Virology.Additional Terms:Arbovirus, Dengue Virus, Emerging Infectious Disease, Molecular Epidemiology, Molecular Genetics, Molecular Virology, Moleular Evolution, Phylogenetics, RNA Virus, Viral Envelope Glycoproteins, Virus Evolution.Languages(Reading, Writing, Speaking)English: (Fluent, Fluent, Fluent) German: (Basic, Basic, Basic) MembershipsAmerican Society for Microbiology American Society for Virology American Society of Tropical Medicine and Hygiene Honors and Awards2008, "60 Under 60",
University of the West Indies,
Recognised a one of UWI 60 most outstanding researchers under 60 as part of UWI 60th anniversary celebrations
2004-2005,
Commonwealth Fellowship,
Commonwealth Fellowship Commission in the UK,
Department of Zoology, University of Oxford,
Molecular Evolution and Phylogenetics
1987, Trinidad and Tobago National Scholarship,
Trinidad and Tobago Government
Previous Positions1996-2006, Lecturer,
University of the West Indies,
St. Augustine Campus,
Pre-Clinical Sciences
1994-1995, Postdoctoral Research Fellow,
Chester Beatty Laboratories,
Institute of Cancer Research
Publications- Suepaul SM, Carrington CV, Campbell M, Borde G, Adesiyun AA (Oct 2009) Serovars of Leptospira isolated from dogs and rodents., Epidemiology and infection, 1-12
 - Auguste AJ, Volk SM, Arrigo NC, Martinez R, Ramkissoon V, Adams AP, Thompson NN, Adesiyun AA, Chadee DD, Foster JE, Travassos Da Rosa AP, Tesh RB, Weaver SC, Carrington CV (Sep 2009) Isolation and phylogenetic analysis of Mucambo virus (Venezuelan equine encephalitis complex subtype IIIA) in Trinidad., Virology, 392 (1), 123-30
 - Norman PJ, Abi-Rached L, Gendzekhadze K, Hammond JA, Moesta AK, Sharma D, Graef T, McQueen KL, Guethlein LA, Carrington CV, Chandanayingyong D, Chang YH, Crespí C, Saruhan-Direskeneli G, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, Milà J, Park MH, Pitchappan RM, Ramdath DD, Shiau MY, Stephens HA, Struik S, Tyan D, Verity DH, Vaughan RW, Davis RW, Fraser PA, Riley EM, Ronaghi M, Parham P (2009) Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes., Genome Research, 19 (5), 759-69
- Kim DY, Guzman H, Bueno R, Dennett JA, Auguste AJ, Carrington CV, Popov VL, Weaver SC, Beasley DW, Tesh RB (Mar 2009) Characterization of Culex Flavivirus (Flaviviridae) strains isolated from mosquitoes in the United States and Trinidad., Virology, 386 (1), 154-9
 - Auguste AJ, Pybus OG, Carrington CV (May 2009) Evolution and dispersal of St. Louis encephalitis virus in the Americas., Infection, genetics and evolution, 9, 709-715
 - Carrington CVF, Foster JE, Zhu HC, Zhang JX, Smith GJD, Thompson N, Auguste AJ, Ramkissoon V, Adesiyun AA, Guan Y (Dec 2008) Detection and phylogenetic analysis of group 1 coronaviruses in South American bats, Emerging Infectious Diseases, 14 (12), 1890-3
- Norman PJ, Abi-Rached L, Gendzekhadze K, Korbel D, Gleimer M, Rowley D, Bruno D, Carrington CV, Chandanayingyong D, Chang YH, Crespí C, Saruhan-Direskeneli G, Fraser PA, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, Milà J, Park MH, Pitchappan RM, Ramdath DD, Shiau MY, Stephens HA, Struik S, Verity DH, Vaughan RW, Tyan D, Davis RW, Riley EM, Ronaghi M, Parham P (Sep 2007) Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans., Nature genetics, 39 (9), 1092-9
 - Carrington CVF, Foster JE, Pybus OG, Bennett SN, Holmes EC (2005) The invasion and maintenance of Dengue virus type 2 and type 4 in the Americas, Journal of Virology, 79 (23), 14680-87
- Brown, T.U., Babb, K., Nimrod, M, Carrington, C.V.F, Salas, R.A., Monteil, M.A., Retrospective Study of the 1996 DEN-1 Epidemic in Trinidad: Demographic and Clinical Features., Dengue Bulletin, 28, 7-19, Dec 2004
- Norman, P.J., Cook, M.A., Carey, B.S., Carrington, C.V.F., Verity, D.H., Hameed, K., Ramdath, D.D., Chandanayingyong, D., Stephens, H.A.F., Leppert, M., Vaughan, R.W., Evolutionary topology of leukocyte receptor cluster haplotypes, Immunogenetics, 56(4), 225 - 37, July 2004
- Foster, J.E., Bennett, S., Carrington, C.V.F. Vaughan, H., Vorndam, V., and McMillan, W. O., Phylogeography and molecular evolution of dengue 2 in the Caribbean basin 1981 - 2000, Virology, 324(1), 48 - 59, 20 Jun 2004
- Plummer W.B., Pereira L.M., Carrington C.V., Pfcrt and pfmdr1 alleles associated with chloroquine resistance in Plasmodium falciparum from Guyana, South America, Mem Inst Oswaldo Cruz., 99(4), 389-92, 2004
- Foster JE, Bennett SN, Vaughan H, Vorndam V, McMillan WO, Carrington CV, Molecular evolution and phylogeny of dengue type 4 virus in the Caribbean, Virology, 306(1), 126-34, February 2003
 - Carrington, C.V.F., Norman, P. J., Vaughan, R. W., Kondeatis, E., Ramdath, D.D., Hameed, K., and Stephens, H. A.F., Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies, European journal of Immunogenetics, 30, 375 – 379, 2003
- Norman PJ, Carrington CV, Byng M, Maxwell LD, Curran MD, Stephens HA, Chandanayingyong D, Verity DH, Hameed K, Ramdath DD, Vaughan RW, Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in
African and South Asian populations, Genes and Immunity, 3(2), 86-95, April 2002
 - Tchilian EZ, Dawes R, Ramaley PA, Whitworth JA, Yuldasheva N, Wells SR, Watera C, French N, Gilks CF, Kunachiwa W, Ruzibakiev R, Leetrakool N, Carrington CV, Ramdath DD, Gotch F, Stephens HA, Hill AV, Beverley PC, A CD45 polymorphism associated with abnormal splicing is absent in African
populations, Immunogenetics, 53(10-11), 980-3, February 2002
 - Carrington, C.V.F., Vaughan, B., Ramdath, D.D., Kondeatis, E., Norman, P. J. and Stephens, H., A comparison of molecular HLA-DR and DQ allele profiles forming DR51, DR52 and DR53 related haplotypes in three ethnic groups in Trinidad, Human Immunology, 63, 1045-1054, 2002
- Hegele RA, Ban MR, Carrington CV, Ramdath DD, Allele frequencies for candidate genes in atherosclerosis and diabetes among Trinidadian neonates, Human Biology, 73(4), 525-31, August 2001
 - Hegele RA, Ramdath DD, Ban MR, Carruthers MN, Carrington CV, Cao H, Polymorphisms in PNLIP, encoding pancreatic lipase, and associations with metabolic traits, Journal of Human Genetics, 46(6), 320-4, 2001
 - Babb K, Carrington CV, Monteil MA, A preliminary study of neopterin as a potential marker for severe dengue virus infection, Transactions of the Royal Society of Tropical Medicine and Hygiene, 93(4), 447-8, 1999
 - Carrington CV, Paul N, Cordell J, Schulz TF, Probing the conformation of the human T-lymphotropic virus I envelope protein complex with monoclonal antibodies, Journal of General Virology, 77 (Pt 9), 2025-9, September 1996
 - Denesvre C, Carrington C, Corbin A, Takeuchi Y, Cosset FL, Schulz T, Sitbon M, Sonigo P, TM domain swapping of murine leukemia virus and human T-cell leukemia virus envelopes confers different infectious abilities despite similar incorporation into virions, Journal of Virology, 70(7), 4380-6, July 1996
 - Carrington, CVF, Schulz, TF, Virology of HTLV-I infection, In: P Hollsberg and DA Hafler (eds). Human T-cell lymphotropic virus type I, 113-139, 1996
- Carrington CV, Weiss RA, Schulz TF, A truncated HTLV-I envelope protein, lacking the hydrophobic membrane anchor domain, is associated with cellular membranes and virions, Virology, 202(1), 61-9, July 1994
 - Miles RJ, Siu EL, Carrington C, Richardson AC, Smith BV, Price RG, The detection of lipase activity in bacteria using novel chromogenic substrates, Fems Microbiology Letters, 69(3), 283-7, 1992
 - Schulz TF, Calabro ML, Hoad JG, Carrington CV, Matutes E, Catovsky D, Weiss RA, HTLV-1 envelope sequences from Brazil, the Caribbean, and Romania: clustering of sequences according to geographic origin and variability in an antibody epitope, Virology, 184(2), 483-91, October 1991

Profile DetailsIndividual Expertise profile of Christine V. F. Carrington, Copyright Christine V. F. Carrington. © COS Expertise TM, 2010, ProQuest LLC All rights reserved. |