Michigan State University College of Osteopathic Medicine Adjunct ProfessorAppointed: 1997 Michigan State University College of Agriculture & Natural Resources Animal Science Associate ProfessorAppointed: 1994 |  |
QualificationsPh.D., University of Michigan, Toxicology, 1987. M.S., Michigan State University, Dairy Science, 1980. B.A., Fu-Jen University, Nutrition, 1973. Expertise and Research InterestsEnvironmental Toxicology Reproduction Fertilization Risk Assessment Endocrine Disruptors
KeywordsCOS Keywords:Animal Science, Birth Or Congenital Defects, Dairy Science, Endocrinology, Environmental Toxicology, Food Safety, Gene Expression, Human Reproduction Or Fertility, Oxidative Stress, Reproduction, Risk Factor Analysis, Toxicology.Additional Terms:Arsenic, Birth Defect, Endocrine Disruptors, Environmental Contaminants, Fertility, Food Safety, Gene Expression, Organophosphates, Oxidative Stress, Reproduction, Risk/Toxicity Assessment, Sperm, Toxicology.Languages(Reading, Writing, Speaking)Chinese, Mandarin: (Fluent, Fluent, Fluent) English: (Fluent, Fluent, Fluent) MembershipsAmerican Association for the Advancement of Science Phi Kappa Phi Sigma Xi, The Scientific Research Society Society for the Study of Reproduction Society of Environmental Toxicology and Chemistry Society of Toxicology Honors and Awards1998, Elected faculty member,
Honor Society of Phi Kappa Phi,
Michigan State University
1996, Women Achieving Excellence
Michigan State University,
Outstandng Accomplishment
1995, Excellence Award for Interdisciplinary Scholarship,
Honor Society of Phi Kappa Phi
Previous Positions1986-1987, Assistant Professor,
Michigan State University,
Natural Science
PatentsMethod of Artificial Insemination by Timed Release of Sperm from Capsules or Solid Beads,
Patent Number: 6596310,
2003,
Institution,
United States of America.
 Method, Device, and Test Kit for Capacitation of Sperm,
Patent Number: Patent 5834225,
1998,
Institution-owned,
United States.
 Funding Received- National Pork Producers Council:
Comprehensive Review on Human Health Effects of Pork Production Emissions,
$25,000,
2001
to 2002.
- National Institutes of Health (NIH):
Training and Research in Environmental Health -- The Balkans,
$1,000,000,
2001
to 2006.
- Animal Initiative Industry Coalition:
Prolonging Sperm Life Span in Storage with a Modified Semen Extender and Hydride Membrane Capsules,
$ 33,000,
1999
to 1999.
- Environmental Protection Agency (EPA):
Developmental Exposure to Endocrine Disruptors: Fertility & Gene Expression Profile Effects,
$ $ 728,000,
1999
to 2003.
- Natinal Food Safety and Toxicology Center:
,
$ 25,000,
1998
to 1998.
- Michgian State University Fundation:
Developing a New Formulation of Boar Semen Extender to Prolong Sperm Life Span in Storage,
$ 10,000,
1998
to 2000.
- Michigan Great Lakes Protection Fund:
,
$242,000,
1998
to 2001.
- NATO:
Basic and Applied Research on Environmental Toxicants (Ochratoxin A & Arsenic) as Potential Causes of Balkan Endemic Nephropathy,
$ 10,000,
1998
to .
- Michigan Great Lakes Protection Fund:
Roles of Carbohydrates and Free Radicals in Controlling Sperm Fertilizing Ability,
$10,000,
1996
to 1997.
- United States Department of Defense (DOD):
In Defense of the Environment,
$ 858,000,
1994
to 1996.
Publications- Fielden MR, Samy SM, Chou KC, Zacharewski TR, Effect of human dietary exposure levels of genistein during gestation and
lactation on long-term reproductive development and sperm quality in
mice, Food and Chemical Toxicology : an International Journal Published for the British Industrial Biologi, 41(4), 447-54, 2003
 - Fielden MR, Halgren RG, Fong CJ, Staub C, Johnson L, Chou K, Zacharewski TR, Gestational and lactational exposure of male mice to diethylstilbestrol
causes long-term effects on the testis, sperm fertilizing ability in
vitro, and testicular gene expression, Endocrinology, 143(8), 3044-59, 2002
 - Fielden, M.R., R.G. Halgren, C.J. Fong, C. Staub, L. Johnson, K. Chou, T.R. Zacharewski, Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on the testis, sperm fertilizing ability in vitro, and testicular gene expression, Endocrinology, 143(8), 3044-3059, 2002
- Chou, K., C. Y. Lin, A. Huang, R. Inglis, and S. Lin, Great Lakes contaminants reduce sperm production and fertilizing ability in mice, Lakes & Reservoirs: Research & Management, 231-239, 2002
- Chou, K., C. Y. Lin, A. Huang, R. Inglis, S. Lin, Great Lakes Contaminants Reduce Sperm Production and Fertilizing Ability in Mice, Lakes and Reservoirs: Research and Management, 7, 231-239, 2002
- Long, D., G. Icopini, V. Ganev, E. Petropoulos, I. Havezov, T. Voice, K. Chou, A. Spassov, and A. S, Geochemistry of Bulgarian soils in villages affected and not affected by Balkan Endemic Nephropathy: A pilot study, Journal of Occupational Medicine and Environmental Health, V(14), 193-196, 2001
- Long, D., G. Icopini, V. Ganev, E. Petropoulos, I. Havezov, T. Voice, K. Chou, Fingerprinting Balkan Endemic Nephropathy in the Bulgarian environment with geochemical markers: a pilot study, Proceedings of the 7th International Conference on Environmental Science and Technology, B, 541-546, 2001
- 6. Long, D., G. Icopini, V. Ganev, E. Petropoulos, I. Havezov, T. Voice, K. Chou, A. Spassov, and A., Geochemistry of Bulgarian soils in villages affected and not affected by Balkan Endemic Nephropathy: A pilot study, Global Network of Environmental Science and Technology, 541-546, 2001
- Fielden M.R., R.G. Halgren, K. Chou, and T.R. Zacharewski, Effects of Gestational and Lactational Exposure to Aroclor 1242 on Testicular Size and Sperm Quality in Early and Middle-Age Male Mice. In: Recent Advances in the Environmental Toxicology and Health E, Environmental Toxicology and Health Effects of PCBs. Eds. Robertson L.W. and Hansen L.G., University, 297-301, 2001
- Fielden, M.R., R. G. Halgren, C. H.M. Tashiro, B. R. Yeo, K. Chou, and T. R. Zacharewski, Effects of gestational and lactational exposure to Aroclor 1242 on testicular size and sperm quality in early adult and middle-age mice, Reproductive Toxicology, 15, 281-292, 2001
- Chou, K., A. Haug, and B. Shi, Arsenic and aluminum speciation in environmental toxicology -- a minireview in metal spceciation in the environment, Global Network of Environmental Science and Technology, 9-19, 1999
- Huang, A, Powel, D. Chou K, Pre- and postnatal exposure to 3,3',4,4'-tetrachlorobiphenyl: I. Effects on breeding ability and sperm fertilizing ability in male mice, Archives of Environmental Contamination and Toxicology, 34, 204-208, 1998
- Mousa M.A., Ganey P.E., Quensen J.F., Madhukar B.V., Chou K., Giesy J.P., Fischer L.J., S. A. Boyd, Altered biological activities of commercial PCB mixtures after microbial reductive dechlorination, Environmental Health Perspectives, 106(6), 1409-1418, 1998
- Chou, K. and B. Salem (Ed. P. Wexler), Endocirne System, Encylcopedia of Toxicology, 531-535, 1998
- Huang, A., Lin, S., Powell, D., Chou, K.,, Pre- and postnatal exposure to 3,3',4,4'-tetrachlorobiphenyl: II. Effects on the reproductive capacity and fertilizing ability of eggs in female mice, Archives of Environmental Contamination and Toxicology, 34, 209-214, 1998
- Mousa, M.A., Quensen, J.H. III, Chou, K., Boyd, S.A., Microbial dechloriantion alleviates inhibitory effects of PCBs on mouse gamete fertilization in vitro, Environmental Science and Technology, 30(6), 2087-2092, 1996
- Yang H H, Aulerich R J, Helferich W, Yamini B, Chou K C, Miller E R, Bursian S J, Effects of zearalenone and/or tamoxifen on swine and mink reproduction., Journal of Applied Toxicology, 15(3), 223-32, May 1995
 - Chou K, Cook R M, Acetylcholine prevents toxic effects of paraoxon on mouse sperm., Bulletin of Environmental Contamination and Toxicology, 54(2), 251-7, February 1995
 - Chou K C, Cook R M, Paraoxon inhibits fertilization of mouse gametes in vitro., Bulletin of Environmental Contamination and Toxicology, 53(6), 863-8, December 1994
 - Kamrin M A, Carney E W, Chou K, Cummings A, Dostal L A, Harris C, Henck J W, Loch-Caruso R, Miller R K, Female reproductive and developmental toxicology: overview and current approaches., Toxicology Letters, 74(2), 99-119, November 1994
 - Wei, K., Z. Dong, H. D. Stowe, and K. Chou, Interactive effects of selenium and copper on reproductive system of male rats, Journal of Guizhou Agricuulture College, 1(24), 28-31, 1994
- Shi B, Chou K, Haug A, Aluminium impacts elements of the phosphoinositide signalling pathway in neuroblastoma cells., Molecular and Cellular Biochemistry, 121(2), 109-18, 21 Apr 1993
 - Shi B, Chen L, Chou K, Haug A, Elevation of intracellular free calcium levels in sperm in response to long-term feeding of fungicides to mice., Journal of Environmental Science and health. Part B: Pesticides, Food Contaminants, and Agricultural, 27(1), 1-8, February 1992
 - Shi B, Oswalt M D, Chou K, Haug A, Loss of inositol phospholipids in epididymal sperm following exposure of mice to long-term feeding of organophosphates., Pharmacology and Toxicology, 70(1), 75-6, January 1992
 - Brondani A, Towns R, Chou K, Cook R M, Barradas H, Effects of isoacids, urea, and sulfur on ruminal fermentation in sheep fed high fiber diets., Journal of Dairy Science, 74(8), 2724-7, August 1991
 - Zhou R, Shi B, Chou K C, Oswalt M D, Haug A, Changes in intracellular calcium of porcine sperm during in vitro incubation with seminal plasma and a capacitating medium., Biochemical and Biophysical Research Communications, 172(1), 47-53, 15 Oct 1990
 - Chou K, Chen J, Yuan S X, Haug A, The membrane potential changes polarity during capacitation of murine epididymal sperm., Biochemical and Biophysical Research Communications, 165(1), 58-64, 30 Nov 1989
 - Cosby, N., K. Chou, and W.R. Dukelow, Embryo production in B6D2-F1 mice using two superovulating regimens, Laboratory Animal Science, 39, 249-250, 1989
- Wei, K., H.D. Stowe, A. House, K. Chou, and T. Thiel, Comparison of cupric and sulfate ion effects on chronic selenosis in rats, Journal of Animal Science, 4, 1467-1475, 1987
Profile DetailsCOS Expertise ID #1244340 Individual Expertise profile of Karen Chou, Copyright Karen Chou. © COS Expertise TM, 2009, ProQuest LLC All rights reserved. |