Dr. Christopher I. Li

powered by
COS Expertise®
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Epidemiology Program
Associate MemberAppointed: 2006
University of Washington
School of Public Health and Community Medicine
Epidemiology
Research Associate ProfessorAppointed: 2006
Professional Headshot of Christopher I. Li

Mailing Address

1100 Fairview Ave. N.
P.O. Box 19024
M4-C308
Seattle, Washington 98109-1024
United States

Contact Information

Phone: (206) 667-7444
Fax: (206) 667-5948
cili@fhcrc.org

Qualifications

Ph.D., University of Washington, Epidemiology, 2002.
M.P.H., University of Washington, Epidemiology, 2000.
M.D., University of California, San Francisco, 2000.
B.S., Stanford University, Biological Sciences, 1995.

Expertise and Research Interests

My research interests lie principally in the field of breast cancer and understanding factors related to its etiology and outcomes using a multidisciplinary approach. I am actively investigating the relationships between various hormonal exposures and risks of different types of breast cancer based on their morphology and expression of different tumor markers. I am also interested in breast cancer outcomes and am currently leading studies that investigate risk factors for second primary breast cancer among breast cancer survivors. Another part of my work focuses on identifying markers that could be used for the early detection of different cancers using various proteomic platforms. Finally, I have an interest in examining disparities in cancer stage, treatment, and survival by race/ethnicity.

Keywords

COS Keywords:

Apoptosis, Breast Cancer, Epidemiology, Etiology, Histology, Hormones, Minority Health, Oncogenes, Outcomes Research (Medical).

Additional Terms:

Breast Cancer, Epidemiology, Hormones.

Languages

(Reading, Writing, Speaking)

Spanish: (Basic, Basic, Basic)

Memberships

American Association for Cancer Research

Publications

  • McDougall JA, Li CI (2010) Trends in distant-stage breast, colorectal, and prostate cancer incidence rates from 1992 to 2004: Potential influences of screening and hormonal factors, Hormones and Cancer
  • Reichman ME, Altekruse S, Li CI, Chen VW, Deapen D, Potts M, Wu XC, Morrell D, Hafterson J, Phipps AI, Harlan LC, Reis LG, Edwards BK (2010) Feasibility study for collection of HER2 data by National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results (SEER) Program central cancer registries, Cancer Epidemiol Biomarkers Prev, 19 (1), 144-147
  • Phipps AI, Mirick D, Li CI, Davis S (2009) Environmental and Occupational Exposures In Christopher I Li (eds), Breast Cancer Epidemoology, New York, Springer, 183-222 pages, ISBN=9781441906847 (bookchapter)
  • Li CI, Beaber EF (2009) Exogenous Hormones In Christopher I Li (eds), Breast Cancer Epidemiology, New York, Springer, 89-118 pages, ISBN=9781441906847 (bookchapter)
  • Phipps AI, Li CI (2009) Endogenous Hormones In Christopher I Li (eds), Breast Cancer Epidemiology, New York, Springer, 73-88 pages, ISBN=9781441906847 (bookchapter)
  • Li CI, Phipps AI (2009) Breast Cancer Biology and Clinical Characteristics In Christopher I Li (eds), Breast Cancer Epidemiology, New York, Springer, 21-46 pages, ISBN=9781441906847 (bookchapter)
  • Reding KW, Li CI, Weiss NS, Chen C, Carlson CS, Duggan D, Thummel KE, Daling JR, Malone KE (2009) Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk., American journal of epidemiology, 170 (10), 1241-1249 Abstract
  • Li CI, Daling JR, Porter PL, Tang MT, Malone KE (2009) Relationship Between Potentially Modifiable Lifestyle Factors and Risk of Second Primary Contralateral Breast Cancer Among Women Diagnosed With Estrogen Receptor-Positive Invasive Breast Cancer., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27 (32), 5301-5302 Abstract
  • Li CI, Daling JR, Porter PL, Tang MC, Malone KE (2009) Adjuvant Hormonal Therapy for Breast Cancer and Risk of Hormone Receptor-Specific Subtypes of Contralateral Breast Cancer, Cancer Research, 69, 6865-6870
  • Li CI, Mathes RW, Malone KE, Daling JR, Bernstein L, Marchbanks PA, Strom BL, Simon MS, Press MF, Deapen D, Burkman RT, Folger SG, McDonald JA, Spirtas R (2009) Relationship between migraine history and breast cancer risk among premenopausal and postmenopausal women., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 18 (7), 2030-2034 Abstract
  • Shah CA, Goff BA, Lowe K, Peters WA, Li CI (2009) Factors affecting risk of mortality in women with vaginal cancer., Obstetrics and gynecology, 113 (5), 1038-10 Abstract
  • Reding KW, Weiss NS, Chen C, Li CI, Carlson CS, Wilkerson HW, Farin FM, Thummel KE, Daling JR, Malone KE (2009) Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 18 (5), 1461-1467 Abstract
  • Welsh ML, Buist DS, Aiello Bowles EJ, Anderson ML, Elmore JG, Li CI (Apr 2009) Population-based estimates of the relation between breast cancer risk, tumor subtype, and family history., Breast cancer research and treatment, 114 (3), 549-58 Abstract
  • Loo LW, Ton C, Wang YW, Grove DI, Bouzek H, Vartanian N, Lin MG, Yuan X, Lawton TL, Daling JR, Malone KE, Li CI, Hsu L, Porter PL (Dec 2008) Differential patterns of allelic loss in estrogen receptor-positive infiltrating lobular and ductal breast cancer., Genes, chromosomes & cancer, 47 (12), 1049-66 Abstract
  • Beaber EF, Holt VL, Malone KE, Porter PL, Daling JR, Li CI (Dec 2008) Reproductive factors, age at maximum height, and risk of three histologic types of breast cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (12), 3427-34 Abstract
  • Mathes RW, Malone KE, Daling JR, Davis S, Lucas SM, Porter PL, Li CI (Nov 2008) Migraine in postmenopausal women and the risk of invasive breast cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (11), 3116-22 Abstract
  • Phipps AI, Malone KE, Porter PL, Daling JR, Li CI (Oct 2008) Reproductive and hormonal risk factors for postmenopausal luminal, HER-2-overexpressing, and triple-negative breast cancer., Cancer, 113 (7), 1521-6 Abstract
  • Phipps AI, Malone KE, Porter PL, Daling JR, Li CI (Aug 2008) Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (8), 2078-86 Abstract
  • Kireeva ML, Nedialkov YA, Cremona GH, Purtov YA, Lubkowska L, Malagon F, Burton ZF, Strathern JN, Kashlev M (Jun 2008) Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation., Molecular cell, 30 (5), 557-66 Abstract
  • Mathes RW, Malone KE, Daling JR, Porter PL, Li CI (Jan 2008) Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (1), 67-72 Abstract
  • Mathes RW, Malone KE, Daling JR, Porter PL, Li CI (Jan 2008) Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (1), 67-72 Abstract
  • Li CI, Malone KE, Daling JR, Potter JD, Bernstein L, Marchbanks PA, Strom BL, Simon MS, Press MF, Ursin G, Burkman RT, Folger SG, Norman S, McDonald JA, Spirtas R (Jan 2008) Timing of menarche and first full-term birth in relation to breast cancer risk., American journal of epidemiology, 167 (2), 230-9 Abstract
  • Li CI, Malone KE, Porter PL, Lawton TJ, Voigt LF, Cushing-Haugen KL, Lin MG, Yuan X, Daling JR (Jan 2008) Relationship between menopausal hormone therapy and risk of ductal, lobular, and ductal-lobular breast carcinomas., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (1), 43-50 Abstract
  • Blume HK, Li CI, Loch CM, Koepsell TD (Jan 2008) Intrapartum fever and chorioamnionitis as risks for encephalopathy in term newborns: a case-control study., Developmental medicine and child neurology, 50 (1), 19-24 Abstract
  • McDougall JA, Madeleine MM, Daling JR, Li CI (Dec 2007) Racial and ethnic disparities in cervical cancer incidence rates in the United States, 1992-2003., Cancer causes & control : CCC, 18 (10), 1175-86 Abstract
  • Li CI, Daling JR (Dec 2007) Changes in breast cancer incidence rates in the United States by histologic subtype and race/ethnicity, 1995 to 2004., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (12), 2773-80 Abstract
  • Li CI, Littman AJ, White E (Oct 2007) Relationship between age maximum height is attained, age at menarche, and age at first full-term birth and breast cancer risk., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (10), 2144-9 Abstract
  • Blume HK, Loch CM, Li CI (Jul 2007) Neonatal encephalopathy and socioeconomic status: population-based case-control study., Archives of pediatrics & adolescent medicine, 161 (7), 663-8 Abstract
  • Sun LM, Li CI, Huang EY, Vaughan TL (Feb 2007) Survival differences by race in nasopharyngeal carcinoma., American journal of epidemiology, 165 (3), 271-8 Abstract
  • Sun LM, Li CI, Huang EY, Vaughan TL (Feb 2007) Survival differences by race in nasopharyngeal carcinoma., American journal of epidemiology, 165 (3), 271-8 Abstract
  • Dunnwald LK, Rossing MA, Li CI (2007) Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients., Breast cancer research : BCR, 9 (1), R6 Abstract
  • Wright JL, Porter MP, Li CI, Lange PH, Lin DW (Aug 2006) Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder., Cancer, 107 (4), 721-8 Abstract
  • Li CI, Malone KE, Daling JR (Jun 2006) Interactions between body mass index and hormone therapy and postmenopausal breast cancer risk (United States)., Cancer causes & control : CCC, 17 (5), 695-703 Abstract
  • Li CI, Malone KE, Saltzman BS, Daling JR (May 2006) Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ, 1988-2001., Cancer, 106 (10), 2104-12 Abstract
  • Li CI, Daling JR, Malone KE, Bernstein L, Marchbanks PA, Liff JM, Strom BL, Simon MS, Press MF, McDonald JA, Ursin G, Burkman RT, Deapen D, Spirtas R (May 2006) Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 15 (5), 946-54 Abstract
  • Chien C, Li CI, Heckbert SR, Malone KE, Boudreau DM, Daling JR (Jan 2006) Antidepressant use and breast cancer risk., Breast cancer research and treatment, 95 (2), 131-40 Abstract
  • Sun LM, Epplein M, Li CI, Vaughan TL, Weiss NS (Dec 2005) Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002., American journal of epidemiology, 162 (12), 1174-8 Abstract
  • Li CI, Uribe DJ, Daling JR (Oct 2005) Clinical characteristics of different histologic types of breast cancer., British journal of cancer, 93 (9), 1046-52 Abstract
  • Li CI, Malone KE, Daling JR (Oct 2005) The relationship between various measures of cigarette smoking and risk of breast cancer among older women 65-79 years of age (United States)., Cancer Causes & Control : Ccc, 16 (8), 975-85 Abstract
  • Chien C, Morimoto LM, Tom J, Li CI (Aug 2005) Differences in colorectal carcinoma stage and survival by race and ethnicity., Cancer, 104 (3), 629-39 Abstract
  • Fesinmeyer MD, Austin MA, Li CI, De Roos AJ, Bowen DJ (Jul 2005) Differences in survival by histologic type of pancreatic cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 14 (7), 1766-73 Abstract
  • Li CI, Racial and Ethnic Disparities in Breast Cancer Stage, Treatment, And Survival in the United States., Ethnicity & Disease, 15(2 Suppl 2), S5-9, Spring 2005 Abstract
  • Li CI, Daling JR, Malone KE, Age-specific Incidence Rates of in Situ Breast Carcinomas By Histologic Type, 1980 to 2001., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology., 14(4), 1008-11, Apr 2005 Abstract
  • Chen CC, Li TC, Li CI, Liu CS, Wang HJ, Lin CC (Apr 2005) Serum resistin level among healthy subjects: relationship to anthropometric and metabolic parameters., Metabolism: clinical and experimental, 54 (4), 471-5 Abstract
  • Voigt LF, Boudreau DM, Weiss NS, Malone KE, Li CI, Daling JR, Re: "studies With Low Response Proportions May Be Less Biased Than Studies With High Response Proportions"., American Journal of Epidemiology, 161(4), 401-2; author reply, Feb 2005 Abstract
  • Loo LW, Grove DI, Williams EM, Neal CL, Cousens LA, Schubert EL, Holcomb IN, Massa HF, Glogovac J, Li CI, Malone KE, Daling JR, Delrow JJ, Trask BJ, Hsu L, Porter PL, Array Comparative Genomic Hybridization Analysis of Genomic Alterations In Breast Cancer Subtypes., Cancer Research, 64(23), 8541-9, Dec 2004 Abstract
  • Li CI, Postmenopausal Hormone Therapy and the Risk of Breast Cancer: the View Of An Epidemiologist., Maturitas, 49(1), 44-50, Sep 2004 Abstract
  • Li CI, Moe RE, Daling JR, Risk of mortality by histologic type of breast cancer among women aged 50 to 79 years, Archives of Internal Medicine, 163(18), 2149-53, October 2003 Abstract
  • Li CI, Malone KE, Weiss NS, Boudreau DM, Cushing-Haugen KL, Daling JR, Relation between use of antihypertensive medications and risk of breast carcinoma among women ages 65-79 years, Cancer, 98(7), 1504-13, October 2003 Abstract
  • Li CI, Malone KE, Porter PL, Daling JR, Epidemiologic and molecular risk factors for contralateral breast cancer among young women, British Journal of Cancer, 89(3), 513-8, August 2003 Abstract
  • Li CI, Malone KE, Porter PL, Weiss NS, Tang MT, Cushing-Haugen KL, Daling JR, Relationship between long durations and different regimens of hormone therapy and risk of breast cancer, Jama : the Journal of the American Medical Association, 289(24), 3254-63, June 2003 Abstract
  • Li CI, Daling JR, Emanuel I, Birthweight and risk of overall and cause-specific childhood mortality, Paediatric and Perinatal Epidemiology, 17(2), 164-70, April 2003 Abstract
  • Li CI, Anderson BO, Daling JR, Moe RE, Trends in incidence rates of invasive lobular and ductal breast carcinoma, Jama : the Journal of the American Medical Association, 289(11), 1421-4, March 2003 Abstract
  • Li CI, Malone KE, Daling JR, Differences in breast cancer stage, treatment, and survival by race and ethnicity, Archives of Internal Medicine, 163(1), 49-56, January 2003 Abstract
  • Li CI, Daling JR, Malone KE, Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(1), 28-34, January 2003 Abstract
  • Li CI, Malone KE, Porter PL, Weiss NS, Tang MC, Daling JR, The relationship between alcohol use and risk of breast cancer by histology and hormone receptor status among women 65-79 years of age, Cancer Epidemiol Biomarker Prev, 12, 1061-1066, 2003
  • Li CI, Malone KE, Porter PL, Weiss NS, Tang MC, Daling JR, Reproductive and anthropometric factors in relation to the risk of lobular and ductal breast carcinoma among women 65-79 years of age, Int J Cancer, 107, 647-651, 2003
  • Li CI, Malone KE, Daling JR, Differences in Breast Cancer Stage, Treatment, and Survival By Race And Ethnicity., Archives of Internal Medicine, 163(1), 49-56, Jan 2003
  • Li CI, Daling JR, Malone KE, Incidence of Invasive Breast Cancer By Hormone Receptor Status From 1992 to 1998., Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(1), 28-34, Jan 2003
  • Li CI, Malone KE, Daling JR, Differences in Breast Cancer Stage, Treatment, and Survival By Race And Ethnicity., Archives of Internal Medicine, 163(1), 49-56, Jan 2003 Abstract
  • Li CI, Anderson BO, Daling JR, Moe RE, Changing incidence of lobular carcinoma in situ of the breast, Breast Cancer Research and Treatment, 75(3), 259-68, October 2002 Abstract
  • Li CI, Malone KE, Daling JR, Differences in breast cancer hormone receptor status and histology by race and ethnicity among women 50 years of age and older, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 11(7), 601-7, July 2002 Abstract
  • Li CI, Malone KE, Weiss NS, Daling JR, Tamoxifen therapy for primary breast cancer and risk of contralateral breast cancer, Journal of the National Cancer Institute, 93(13), 1008-13, July 2001 Abstract
  • Li CI, Rossing MA, Voigt LF, Daling JR, Multiple primary breast and thyroid cancers: role of age at diagnosis and cancer treatments (United States), Cancer Causes & Control : Ccc, 11(9), 805-11, October 2000 Abstract
  • Li CI, Weiss NS, Stanford JL, Daling JR, Hormone replacement therapy in relation to risk of lobular and ductal breast carcinoma in middle-aged women, Cancer, 88(11), 2570-7, June 2000 Abstract
  • Li CI, Anderson BO, Porter P, Holt SK, Daling JR, Moe RE, Changing incidence rate of invasive lobular breast carcinoma among older women, Cancer, 88(11), 2561-9, June 2000 Abstract
  • Li CI, Stanford JL, Daling JR, Anthropometric variables in relation to risk of breast cancer in middle-aged women, International Journal of Epidemiology, 29(2), 208-13, April 2000 Abstract
  • van Oers HJ, de Kloet ER, Li C, Levine S, The ontogeny of glucocorticoid negative feedback: influence of maternal deprivation, Endocrinology, 139(6), 2838-46, June 1998 Abstract
  • Li CI, Malone KE, White E, Daling JR, Age when maximum height is reached as a risk factor for breast cancer among young U.S. women, Epidemiology (cambridge, Mass.), 8(5), 559-65, September 1997 Abstract
  • Li SA, Xue Y, Xie Q, Li CI, Li JJ, Serum and tissue levels of estradiol during estrogen-induced renal tumorigenesis in the Syrian hamster, Journal of Steroid Biochemistry and Molecular Biology, 48(2-3), 283-6, February 1994 Abstract

Profile Details

Last Verified: 2/16/2010

COS Expertise ID #1051347
Reference this profile directly: http://myprofile.cos.com/cili