Dr. Chloe Lynne Thio

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Johns Hopkins University
School of Medicine
Medicine
Infectious Diseases
Associate Professor

Mailing Address

1503 E. Jefferson St.
Baltimore, Maryland 21231
United States

Contact Information

Phone: (410) 955-0349
Fax: (410) 614-7564
cthio@jhmi.edu

Qualifications

M.D., Yale University, 1992.
B.A., University of Pennsylvania, Biochemistry, 1987.

Expertise and Research Interests

HIV
Hepatitis B
Hepatitis C
Genetics

Keywords

COS Keywords:

Genetics, Hepatitis, HIV, Infectious Diseases or Agents.

Additional Terms:

Human Genetics, Infectious Diseases, Viral Hepatitis.

Memberships

American College of Physicians
American Society of Human Genetics
Infectious Diseases Society of America

Previous Positions

1996-2000, Fellow, Johns Hopkins University, School of Medicine, Medicine, Infectious Diseases

Funding Received

  • National Institutes of Health (NIH): HIV-HBV co-infection in resource limited settings, 2006 to 2011.
  • National Institutes of Health (NIH): HIV/HBV and Liver Disease Progression in HAART Era, 2004 to 2009.
  • Burroughs-Wellcome Fund: Host Genetics and Hepatitis B Virus Outcomes, $400,000, 2002 to 2008.

Publications

  • Thio CL, Sulkowski MS, Thomas DL (Oct 2005) Treatment of chronic hepatitis B in HIV-infected persons: thinking outside the black box., Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 41 (7), 1035-40 Abstract
  • Thio CL, Mosbruger T, Astemborski J, Greer S, Kirk GD, O'Brien SJ, Thomas DL (Jul 2005) Mannose binding lectin genotypes influence recovery from hepatitis B virus infection., Journal of Virology, 79 (14), 9192-6 Abstract
  • Oleksyk TK, Thio CL, Truelove AL, Goedert JJ, Donfield SM, Kirk GD, Thomas DL, O'Brien SJ, Smith MW (Jun 2005) Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance., Genes and Immunity, 6 (4), 347-57 Abstract
  • Soriano V, Puoti M, Bonacini M, Brook G, Cargnel A, Rockstroh J, Thio C, Benhamou Y (Feb 2005) Care of patients with chronic hepatitis B and HIV co-infection: recommendations from an HIV-HBV International Panel., Aids (london, England), 19 (3), 221-40 Abstract
  • Soriano V, Puoti M, Bonacini M, Brook G, Cargnel A, Rockstroh J, Thio C, Benhamou Y (Feb 2005) Care of patients with chronic hepatitis B and HIV co-infection: recommendations from an HIV-HBV International Panel., Aids (london, England), 19 (3), 221-40 Abstract
  • Thio CL, Mosbruger TL, Kaslow RA, Karp CL, Strathdee SA, Vlahov D, O'Brien SJ, Astemborski J, Thomas DL (Oct 2004) Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection., Journal of Virology, 78 (20), 11258-62 Abstract
  • Khakoo SI, Thio CL, Martin MP, Brooks CR, Gao X, Astemborski J, Cheng J, Goedert JJ, Vlahov D, Hilgartner M, Cox S, Little AM, Alexander GJ, Cramp ME, O'Brien SJ, Rosenberg WM, Thomas DL, Carrington M (Aug 2004) HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection., Science, 305 (5685), 872-4 Abstract
  • Karacki PS, Gao X, Thio CL, Thomas DL, Goedert JJ, Vlahov D, Kaslow RA, Strathdee S, Hilgartner MW, O'Brien SJ, Carrington M (Jun 2004) MICA and recovery from hepatitis C virus and hepatitis B virus infections., Genes and Immunity, 5 (4), 261-6 Abstract
  • Thio CL, Goedert JJ, Mosbruger T, Vlahov D, Strathdee SA, O'Brien SJ, Astemborski J, Thomas DL (Jun 2004) An analysis of tumor necrosis factor alpha gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection., Genes and Immunity, 5 (4), 294-300 Abstract
  • Thio CL, Netski DM, Myung J, Seaberg EC, Thomas DL, Changes in Hepatitis B Virus DNA Levels With Acute HIV Infection., Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America., 38(7), 1024-9, Apr 2004 Abstract
  • Thio CL, Management of Chronic Hepatitis B in the HIV-infected Patient., The Aids Reader, 14(3), 122-9, 133, 136-7, Mar 2004 Abstract
  • Thio CL, Thomas DL, Karacki P, Gao X, Marti D, Kaslow RA, Goedert JJ, Hilgartner M, Strathdee SA, Duggal P, O'Brien SJ, Astemborski J, Carrington M (Nov 2003) Comprehensive analysis of class I and class II HLA antigens and chronic hepatitis B virus infection., Journal of Virology, 77 (22), 12083-7 Abstract
  • Thio CL, Treatment of chronic hepatitis B in the HIV-infected patient., The Hopkins Hiv Report : a Bimonthly Newsletter for Healthcare Providers / Johns Hopkins University Aids Service., 15(4), 9, 12, Jul 2003 Abstract
  • Thio CL, Hepatitis B in the human immunodeficiency virus-infected patient: epidemiology, natural history, and treatment, Seminars in Liver Disease, 23(2), 125-36, May 2003 Abstract
  • Thio CL, Seaberg EC, Skolasky R Jr, Phair J, Visscher B, Munoz A, Thomas DL, Multicenter AIDS Cohort Study, HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS), Lancet, 360(9349), 1921-6, December 2002 Abstract
  • Thio CL, Gao X, Goedert JJ, Vlahov D, Nelson KE, Hilgartner MW, O'Brien SJ, Karacki P, Astemborski J, Carrington M, Thomas DL, HLA-Cw*04 and hepatitis C virus persistence, Journal of Virology, 76(10), 4792-7, May 2002 Abstract
  • Thio CL, Thomas DL, Goedert JJ, Vlahov D, Nelson KE, Hilgartner MW, O'Brien SJ, Karacki P, Marti D, Astemborski J, Carrington M, Racial differences in HLA class II associations with hepatitis C virus outcomes, The Journal of Infectious Diseases, 184(1), 16-21, July 2001 Abstract
  • Thio CL, Thomas DL, Carrington M, Chronic viral hepatitis and the human genome, Hepatology (baltimore, Md.), 31(4), 819-27, April 2000 Abstract
  • Thio CL, Nolt KR, Astemborski J, Vlahov D, Nelson KE, Thomas DL, Screening for hepatitis C virus in human immunodeficiency virus-infected individuals, Journal of Clinical Microbiology, 38(2), 575-7, February 2000 Abstract
  • Thio CL, Smith D, Merz WG, Streifel AJ, Bova G, Gay L, Miller CB, Perl TM, Refinements of environmental assessment during an outbreak investigation of invasive aspergillosis in a leukemia and bone marrow transplant unit, Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America., 21(1), 18-23, Jan 2000 Abstract
  • Thio CL, Carrington M, Marti D, O'Brien SJ, Vlahov D, Nelson KE, Astemborski J, Thomas DL, Class II HLA alleles and hepatitis B virus persistence in African Americans, The Journal of Infectious Diseases, 179(4), 1004-6, April 1999 Abstract
  • Chan-Tack KM, Thio CL, Miller NS, Karp CL, Ho C, Merz WG, Paecilomyces lilacinus fungemia in an adult bone marrow transplant recipient, Medical Mycology : Official Publication of the International Society for Human and Animal Mycology., 37(1), 57-60, February 1999 Abstract
  • Utzschneider DA, Thio C, Sontheimer H, Ritchie JM, Waxman SG, Kocsis JD (Dec 1993) Action potential conduction and sodium channel content in the optic nerve of the myelin-deficient rat., Proceedings of the Royal Society of London. Series B. Biological Sciences, 254 (1341), 245-50 Abstract
  • Thio CL, Sontheimer H (Nov 1993) Differential modulation of TTX-sensitive and TTX-resistant Na+ channels in spinal cord astrocytes following activation of protein kinase C., The Journal of Neuroscience : the Official Journal of the Society for Neuroscience., 13 (11), 4889-97 Abstract
  • Thio CL, Rutledge TM, Cost-effective treatment of Candida esophagitis., Annals of Internal Medicine, 118(10), 824-5, May 1993 Abstract
  • Thio CL, Waxman SG, Sontheimer H (Mar 1993) Ion channels in spinal cord astrocytes in vitro. III. Modulation of channel expression by coculture with neurons and neuron-conditioned medium., Journal of Neurophysiology, 69 (3), 819-31 Abstract

Profile Details

Last Verified: 10/12/2007

COS Expertise ID #1144308
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