Dr. Catherine L. Troisi

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University of Texas Health Science Center at Houston
School of Public Health
Center for Infectious Disease
Biological Sciences
Assistant ProfessorAppointed: 1997
University of Texas Health Science Center at Houston
UTHSC Centers, Institutes and Programs
Center for Infectious Disease
Associate DirectorAppointed: 2001

Mailing Address

University of Texas Health Science Center at Houston
School of Public Health
1200 Hermann Pressler Dr., RAS E-729
Houston, Texas 77030
United States

Contact Information

Phone: (713) 500-9396
Fax: (713) 500-9359
Catherine.L.Troisi@uth.tmc.edu

Qualifications

Ph.D., University of Michigan, Epidemiologic Sciences, 1980.
M.S., Michigan State University, Biochemistry, 1975.
B.A., University of Rochester, Chemistry, 1974.

Expertise and Research Interests

My research is in the area of viral hepatitis, both laboratory and field based. Previous studies have included clinical trials of hepatitis A and hepatitis B vaccines and laboratory validation of new immunodiagnostic kits for hepatitis A and B. A major area of research has been in the hemophilic community where we evaluated interactions between hepatitis B, hepatitis C, hepatitis D, and HIV infection in co-infected individuals as well as the natural history of HCV disease. In addition, other on-going research projects include development of a combined enzyme immunoassay for the detection of antibodies to hepatitis C and HIV and development of an immune complex dissociation assay capable of detecting anti-HCV antibodies in antibody negative/PCR positive individuals. In the future, I plan on setting up a study looking at transmission of hepatitis C virus in households with a hemophilic patient and setting up PCR laboratory at the School of Public Health.

Another area of interest is that of immune response to vaccination in the elderly and the effect of estrogen on this response. We are currently planning a study of HAV vaccine in elderly women who are on hormone replacement therapy and will compare their response to a set of women not on estrogen.

Other Expertise

Academic Experience:
Member, Epidemiology and Disease Control II Study Section, DRG, NIH, 1995-present

Business Experience:
1996, Participated in videotaped discussion entitled ''Antigen content of HBV Vaccines'' for SmithKline Beecham

Committee/Services:
1997, Special Review Panel - National Institute of Allergy & Infectious Diseases, NIH
1995 - present, Ad hoc Member, Epidemiology and Disease Control II Study Section
1992, Reverse Site Visit - National Heart, Lung, and Blood Institute, NIH
1990, Special Review Panel - National Institute of Allergy & Infectious Diseases, NIH
1983 - present, Ad hoc reviewer for Journal of Infectious Diseases, Annals of Internal Medicine, JAMA, Journal of Immunology, Journal of Medical Virology, Gastroenterology, Journal of Hepatology, American Journal of Tropical Medicine

Keywords

COS Keywords:

Clinical Trial, Epidemiology, Hemophilia, Hepatitis, HIV, Infectious Diseases Or Agents, Public Health, Vaccine, Virology.

Additional Terms:

Viral Epidemiology, Viral Hepatatitis.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
French: (Functional, Basic, Basic)

Memberships

American Association for the Advancement of Science
American College of Epidemiology
American Society for Microbiology
Society for Epidemiologic Research

Honors and Awards

1979, Sigma Xi (Scientific Honor Society), University of Michigan

Previous Positions

1992-1993, Coordinator, The Texas A&M Health Science Center, Baylor College of Medicine, Virology Reference Laboratory, Virology QA Program, DAIDS
1989-1996, Supervisor, The Texas A&M Health Science Center, Baylor College of Medicine, Eugene B. Casey Hepatitis and HIV Research and Diagnostic Laboratories
1983-1996, Research Assistant Professor (part-time), The Texas A&M Health Science Center, Baylor College of Medicine

Funding Received

  • Womens Fund for Health Education and Research: Effect of Hormone Replacement Therapy on Immune Response, $20,000, 12/99 to 12/00.
  • Development of a Combined Assay for the Detection of Antibodies to HCV and HIV, Gulf Coast Regional Blood Center, $19,517, 1995-1996
  • Evaluation of the Syva Microtrak II IgM anti-HAV EIA,Syva Co., $5,670, 1995
  • Enhancement of HCV Antibody Detection by ICD, Gulf Coast Regional Blood Center, $18,720, 1994-1995

Publications

  • Monga HK, Rodriguez-Barradas MC, Breaux K, Khattak K, Troisi CL, Velez M, Yoffe B, Hepatitis C virus infection-related morbidity and mortality among patients with human immunodeficiency virus infection, Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 33(2), 240-7, July 2001 Abstract
  • Troisi C L, Hollinger F B, Krause D S, Pickering L K, Immunization of seronegative infants with hepatitis A vaccine (HAVRIX; SKB): a comparative study of two dosing schedules., Vaccine, 15(15), 1613-7, October 1997 Abstract
  • Troisi, C.L. and F.B. Hollinger, Detection of Antibodies to Hepatitis C Virus in Seronegative Patients Using an Immune Complex Dissociation Assay, Journal of Viral Hepatitis, 4/6, 383-386, 1997
  • Troisi C L, Hollinger F B, Detection of antibodies to hepatitis C virus in seronegative patients using an immune complex dissociation assay., Journal of Viral Hepatitis, 4(6), 383-6, 1997 Abstract
  • Troisi C L, Hollinger F B, Hoots W K, Contant C, Gill J, Ragni M, Parmley R, Sexauer C, Gomperts E, Buchanan G, et al, A multicenter study of viral hepatitis in a United States hemophilic population., Blood, 81(2), 412-8, 15 Jan 1993 Abstract
  • Troisi C L, Hollinger F B, Hepatitis B vaccines., Progress In Liver Diseases, 9, 405-42, 1990 Abstract
  • Troisi CL, Hollinger FB, Current tests for antibody to hepatitis b core antigen used to screen donors for non-A, non-B hepatitis are comparable to the original radioimmunoassay for hepatitis B core antigen, Transfusion, 27(5), 438-40, 1987 Abstract
  • Hollinger FB, Troisi C, Heiberg D, Sanchez Y, Dreesman GR, Melnick JL, Response to a hepatitis B polypeptide vaccine in micelle form in a young adult population, Journal of Medical Virology, 19(3), 229-40, July 1986 Abstract
  • Pepe PE, Hollinger FB, Troisi CL, Heiberg D, Viral hepatitis risk in urban emergency medical services personnel, Annals of Emergency Medicine, 15(4), 454-7, April 1986 Abstract
  • Hollinger FB, Troisi CL, Pepe PE, Anti-HBs responses to vaccination with a human hepatitis B vaccine made by recombinant DNA technology in yeast, Journal of Infectious Diseases, 153(1), 156-9, January 1986 Abstract
  • Troisi CL, Heiberg DA, Hollinger FB, Normal immune response to hepatitis B vaccine in patients with Down's syndrome. A basis for immunization guidelines, Jama, 254(22), 3196-9, December 1985 Abstract
  • Troisi CL, Hollinger FB, Detection of an IgM antiidiotype directed against anti-HBs in hepatitis B patients, Hepatology, 5(5), 758-62, 1985 Abstract
  • Chin TW, Hollinger FB, Rich RR, Troisi CL, Dreesman GR, Melnick JL, Cytotoxicity by NK-like cells from hepatitis B-immune patients to a human hepatoma cell line secreting HBsAg, Journal of Immunology, 130(1), 173-80, January 1983 Abstract
  • Troisi CL, Monto AS, Comparison of enzyme-linked immunosorbent assay and hemagglutination inhibition in a seroepidemiological study of influenza type C infection, Journal of Clinical Microbiology, 14(5), 516-21, November 1981 Abstract
  • Troisi, C.L., F. B. Hollinger, and the Delta Hepatitis Study Group. "Interactions between hepatitis C and HIV in hemophiliacs: Results of a 7 year follow-up study." 1997 Viral Hepatitis and Liver Disease, M. Rizzetto, ed
  • Troisi, C.L., F. B. Hollinger, D. Krause, and L. Pickering. "Immunization of Infants with Hepatitis A Vaccine (HAVRIX): A comparative study of two dosing schedules" 1997 Viral Hepatitis and Liver Disease, M. Rizzetto, ed
  • Troisi, C.L. and F.B. Hollinger. "Overview of Clinical Trials in Low Endemic Areas" 1993 In: Hepatitis B Vaccines in Clinical Practice, Ronald Ellis, ed., marcel dekker, New York, p179-208

Profile Details

Last Updated: 5/20/2003

COS Expertise ID #409956
Reference this profile directly: http://myprofile.cos.com/ctroisi