Dr. Steven Deem

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University of Washington
School of Medicine
Adjunct, Medicine
Associate ProfessorAppointed: 1994
Professional Headshot of Steven Deem

Mailing Address

Department of Anesthesiology
Harborview Medical Center
Box 359724
Seattle, Washington 98104-2499
United States

Contact Information

Phone: (206) 731-3059
Fax: (206) 731-8009
sdeem@u.washington.edu

Qualifications

M.D., Stanford University, Critical Care Medicine, 1992.
M.D., University of California, San Diego, Anesthesiology, 1991.
M.D., Jewish Hospital, Internal Medicine, 1987.
M.D., Southern Illinois University, 1984.
B.S., Southern Illinois University, 1979.

Expertise and Research Interests

Clinical:
Critical Care Medicine
Co-director, Neurosurgical Critical Care Service, Harborview Medical Center
Program Director, Anesthesiology Critical Care Medicine Fellowship

Research:
Modulation of hypoxic pulmonary vasoconstriction by red blood cells and nitric oxide
Pulmonary microcirculatory physiology
ICU-based outcomes research

Keywords

COS Keywords:

Anesthesiology, Blood Flow, Respiratory Diseases, Respiratory System.

Additional Terms:

Adult, Anesthesia, Hypoxic Pulmonary Vasoconstriction, Nitric Oxide, Pulmonary Cirulation, Respiratory Biology, Respiratory Diseases.

Memberships

American Physiological Society
American Society of Anesthesiologists
American Society of Critical Care Anesthesiologists
American Thoracic Society
International Anesthesia Research Society
Society for Critical Care Medicine

Honors and Awards

2003-2004, Frontiers Award, International Anesthesia Research Society, University of Washington, Hemoglobin, Nitric Oxide, and The Pulmonary Circulation

Funding Received

  • Roche Pharmaceuticals: Unrestricted grant; Insulin and Glycemic Control in Critically Ill Patients, $10,000, 2005 to 2006.
  • National Institutes of Health (NIH): K02 Independent Scientist Award; Red Blood Cells, Nitric Oxide, and the Pulmonary Circulation, $394,000, 2005 to 2009.
  • Washington State Society of Anesthesiology: 2004 WSSA Research Award; Effects of Fluid Therapy on Outcome in Patients with Subarachnoid Hemorrhage., $10,000, 2004 to 2005.
  • International Anesthesia Research Foundation: Frontiers Award; Hemoglobin, Nitric Oxide, and the Pulmonary Circulation, $500,000, 2003 to 2008.
  • National Institutes of Health (NIH): K08 Clinical Investigator Development Award; Red Blood Cells and the Pulmonary Circulation, $520,000, 1998 to 2003.
  • Washington Affiliate: Beginning Grant-in-Aid; Effects of Anemia on Carbon Dioxide Exchange, $68,000, 1996 to 1998.
  • Foundation for Anesthesia Education and Research: Research Starter Grant; Role of the Red Blood Cell in Hypoxic Pulmonary Vasoconstriction, $50,000, 1995 to 1996.

Publications

  • Deem S, Kim SS, Min JH, Eveland R, Moulding J, Martyr S, Wang X, Swenson ER, Gladwin MT (Dec 2004) Pulmonary vascular effects of red blood cells containing S-nitrosated hemoglobin., American Journal of Physiology. Heart and Circulatory Physiology, 287 (6), H2561-8 Abstract
  • Deem S, Souter MJ, B-Aware: recall of intraoperative events., Lancet, 364(9437), 840; author reply 84, Sep 2004 Abstract
  • Deem S (Mar 2004) Nitric oxide scavenging by hemoglobin regulates hypoxic pulmonary vasoconstriction., Free Radical Biology & Medicine, 36 (6), 698-706 Abstract
  • Vaughan DJ, Brogan TV, Kerr ME, Deem S, Luchtel DL, Swenson ER (May 2003) Contributions of nitric oxide synthase isozymes to exhaled nitric oxide and hypoxic pulmonary vasoconstriction in rabbit lungs., American Journal of Physiology. Lung Cellular and Molecular Physiology, 284 (5), L834-43 Abstract
  • Swenson ER, Deem S, Kerr ME, Bidani A (Dec 2002) Inhibition of aquaporin-mediated CO2 diffusion and voltage-gated H+ channels by zinc does not alter rabbit lung CO2 and NO excretion., Clinical Science (london, England : 1979), 103 (6), 567-75 Abstract
  • Deem S, Kim JU, Manjula BN, Acharya AS, Kerr ME, Patel RP, Gladwin MT, Swenson ER (Oct 2002) Effects of S-nitrosation and cross-linking of hemoglobin on hypoxic pulmonary vasoconstriction in isolated rat lungs., Circulation Research, 91 (7), 626-32 Abstract
  • Deem S, Useful information about the pharmacokinetics and pharmacodynamics of midazolam and lorazepam., Anesthesiology, 97(2), 522; author reply 52, Aug 2002 Abstract
  • Deem S, Gladwin MT, Berg JT, Kerr ME, Swenson ER (Apr 2001) Effects of S-nitrosation of hemoglobin on hypoxic pulmonary vasoconstriction and nitric oxide flux., American Journal of Respiratory and Critical Care Medicine, 163 (5), 1164-70 Abstract
  • Berg JT, Deem S, Kerr ME, Swenson ER (Dec 2000) Hemoglobin and red blood cells alter the response of expired nitric oxide to mechanical forces., American Journal of Physiology. Heart and Circulatory Physiology, 279 (6), H2947-53 Abstract
  • Deem S, Hedges RG, Kerr ME, Swenson ER (Oct 2000) Acetazolamide reduces hypoxic pulmonary vasoconstriction in isolated perfused rabbit lungs., Respiration Physiology, 123 (1-2), 109-19 Abstract
  • Deem S, Berg JT, Kerr ME, Swenson ER (May 2000) Effects of the RBC membrane and increased perfusate viscosity on hypoxic pulmonary vasoconstriction., Journal of Applied Physiology (bethesda, Md. : 1985), 88 (5), 1520-8 Abstract
  • Deem S, Swenson ER, Anemia and arterial partial pressure of oxygen., Anesthesiology, 92(1), 284-5, Jan 2000 Abstract

Profile Details

Last Updated: 3/21/2007

COS Expertise ID #307418
Reference this profile directly: http://myprofile.cos.com/deems18