G. Lynis Dohm

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East Carolina University
Brody School of Medicine
Biochemistry
Appointed: 1972

Mailing Address

Brody 5S-36
East Carolina University
Greenville, North Carolina 27858
United States

Contact Information

Phone: (919) 816-2682
Dohm@brody.med.ecu.edu

Keywords

COS Keywords:

Biochemistry.

Publications

  • Houmard JA, O''Neill DS, Zheng D, Hickey MS, Dohm GL, Impact of hyperinsulinemia on myosin heavy chain gene regulation., Journal of Applied Physiology, 86(6), 1828-32, June 1999 Abstract
  • Cox JH, Cortright RN, Dohm GL, Houmard JA, Effect of aging on response to exercise training in humans: skeletal muscle GLUT-4 and insulin sensitivity., Journal of Applied Physiology, 86(6), 2019-25, June 1999 Abstract
  • Zhou Q, Dolan PL, Dohm GL, Dephosphorylation increases insulin-stimulated receptor kinase activity in skeletal muscle of obese Zucker rats., Molecular and Cellular Biochemistry, 194(1-2), 209-16, April 1999 Abstract
  • O''Neill DS, Zheng D, Anderson WK, Dohm GL, Houmard JA, Effect of endurance exercise on myosin heavy chain gene regulation in human skeletal muscle., American Journal of Physiology, 276(2 Pt 2), R414-9, February 1999 Abstract
  • Cortright RN, Zheng D, Jones JP, Fluckey JD, DiCarlo SE, Grujic D, Lowell BB, Dohm GL, Regulation of skeletal muscle UCP-2 and UCP-3 gene expression by exercise and denervation., American Journal of Physiology, 276(1 Pt 1), E217-21, Jan 1999 Abstract
  • Jones J P, Tapscott E B, Olson A L, Pessin J E, Dohm G L, Regulation of glucose transporters GLUT-4 and GLUT-1 gene transcription in denervated skeletal muscle., Journal of Applied Physiology, 84(5), 1661-6, May 1998 Abstract
  • Hickey M S, Pories W J, MacDonald K G Jr, Cory K A, Dohm G L, Swanson M S, Israel R G, Barakat H A, Considine R V, Caro J F, Houmard J A, A new paradigm for type 2 diabetes mellitus: could it be a disease of the foregut?, Annals of Surgery, 227(5), 637-43; discussion 6, May 1998 Abstract
  • Cortright R N, Dohm G L, Mechanisms by which insulin and muscle contraction stimulate glucose transport., Canadian Journal of Applied Physiology, 22(6), 519-30, December 1997 Abstract
  • Cortright R N, Azevedo J L Jr, Hickey M S, Tapscott E B, Dohm G L, Vanadate stimulation of 2-deoxyglucose transport is not mediated by PI 3-kinase in human skeletal muscle., Biochimica Et Biophysica Acta, 1358(3), 300-6, 11 Oct 1997 Abstract
  • Jones J P, Dohm G L, Regulation of glucose transporter GLUT-4 and hexokinase II gene transcription by insulin and epinephrine., American Journal of Physiology, 273(4 Pt 1), E682-7, October 1997 Abstract
  • Jones J P, Roberts B R, Tapscott E B, Dohm G L, Transcriptional regulation of hexokinase II in denervated rat skeletal muscle., Biochemical and Biophysical Research Communications, 238(1), 53-5, 8 Sep 1997 Abstract
  • Hickey M S, Tanner C J, O'Neill D S, Morgan L J, Dohm G L, Houmard J A, Insulin activation of phosphatidylinositol 3-kinase in human skeletal muscle in vivo., Journal of Applied Physiology, 83(3), 718-22, September 1997 Abstract
  • Zhou Q, Dohm G L, Treadmill running increases phosphatidylinostol 3-kinase activity in rat skeletal muscle., Biochemical and Biophysical Research Communications, 236(3), 647-50, 30 Jul 1997 Abstract
  • Ahmad F, Azevedo J L, Cortright R, Dohm G L, Goldstein B J, Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes., Journal of Clinical Investigation, 100(2), 449-58, 15 Jul 1997 Abstract
  • Kristiansen S, Jones J, Handberg A, Dohm G L, Richter E A, Eccentric contractions decrease glucose transporter transcription rate, mRNA, and protein in skeletal muscle., American Journal of Physiology, 272(5 Pt 1), C1734-8, May 1997 Abstract
  • Torrance C J, Usala S J, Pessin J E, Dohm G L, Characterization of a low affinity thyroid hormone receptor binding site within the rat GLUT4 gene promoter., Endocrinology, 138(3), 1215-23, March 1997 Abstract
  • Torrance C J, Devente J E, Jones J P, Dohm G L, Effects of thyroid hormone on GLUT4 glucose transporter gene expression and NIDDM in rats., Endocrinology, 138(3), 1204-14, March 1997 Abstract
  • Youngren J F, Maddux B A, Sasson S, Sbraccia P, Tapscott E B, Swanson M S, Dohm G L, Goldfine I D, Skeletal muscle content of membrane glycoprotein PC-1 in obesity. Relationship to muscle glucose transport., Diabetes, 45(10), 1324-8, October 1996 Abstract
  • Houmard J A, Tyndall G L, Midyette J B, Hickey M S, Dolan P L, Gavigan K E, Weidner M L, Dohm G L, Effect of reduced training and training cessation on insulin action and muscle GLUT-4., Journal of Applied Physiology, 81(3), 1162-8, September 1996 Abstract
  • Zheng D, Wooter M H, Zhou Q, Dohm G L, The effect of exercise on ob gene expression., Biochemical and Biophysical Research Communications, 225(3), 747-50, 23 Aug 1996 Abstract
  • Zheng D, Jones J P, Usala S J, Dohm G L, Differential expression of ob mRNA in rat adipose tissues in response to insulin., Biochemical and Biophysical Research Communications, 218(2), 434-7, 17 Jan 1996 Abstract
  • Houmard J A, Hickey M S, Tyndall G L, Gavigan K E, Dohm G L, Seven days of exercise increase GLUT-4 protein content in human skeletal muscle., Journal of Applied Physiology, 79(6), 1936-8, December 1995 Abstract
  • Carey J O, Azevedo J L Jr, Morris P G, Pories W J, Dohm G L, Okadaic acid, vanadate, and phenylarsine oxide stimulate 2-deoxyglucose transport in insulin-resistant human skeletal muscle., Diabetes, 44(6), 682-8, June 1995 Abstract
  • Dolan P L, Boyd S G, Dohm G L, Differential effect of maturation on insulin- vs. contraction-stimulated glucose transport in Zucker rats., American Journal of Physiology, 268(6 Pt 1), E1154-60, June 1995 Abstract
  • Azevedo J L Jr, Carey J O, Pories W J, Morris P G, Dohm G L, Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle., Diabetes, 44(6), 695-8, June 1995 Abstract
  • Houmard J A, Weidner M D, Dolan P L, Leggett-Frazier N, Gavigan K E, Hickey M S, Tyndall G L, Zheng D, Alshami A, Dohm G L, Skeletal muscle GLUT4 protein concentration and aging in humans., Diabetes, 44(5), 555-60, May 1995 Abstract
  • Neufer P D, Devente J E, Tapscott E B, Dohm G L, Hindlimb perfusion induces GLUT-1 and immediate early gene expression in skeletal muscle., American Journal of Physiology, 268(5 Pt 1), E866-72, May 1995 Abstract
  • Hickey M S, Carey J O, Azevedo J L, Houmard J A, Pories W J, Israel R G, Dohm G L, Skeletal muscle fiber composition is related to adiposity and in vitro glucose transport rate in humans., American Journal of Physiology, 268(3 Pt 1), E453-7, March 1995 Abstract
  • Caro J F, Triester S, Patel V K, Tapscott E B, Frazier N L, Dohm G L, Liver glucokinase: decreased activity in patients with type II diabetes., Hormone and Metabolic Research, 27(1), 19-22, January 1995 Abstract
  • Friedman J E, Caro J F, Pories W J, Azevedo J L Jr, Dohm G L, Glucose metabolism in incubated human muscle: effect of obesity and non-insulin-dependent diabetes mellitus., Metabolism: Clinical and Experimental, 43(8), 1047-54, August 1994 Abstract
  • Burguera B, Elton C W, Caro J F, Tapscott E B, Pories W J, Dimarchi R, Sakano K, Dohm G L, Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor [published erratum appears in Biochem J, Biochemical Journal, 300 ( Pt 3), 781-5, 15 Jun 1994 Abstract
  • Elton C W, Tapscott E B, Pories W J, Dohm G L, Effect of moderate obesity on glucose transport in human muscle., Hormone and Metabolic Research, 26(4), 181-3, April 1994 Abstract
  • Carey J O, Neufer P D, Farrar R P, Veerkamp J H, Dohm G L, Transcriptional regulation of muscle fatty acid-binding protein., Biochemical Journal, 298 Pt 3, 613-7, 15 Mar 1994 Abstract
  • Dudek R W, Dohm G L, Holman G D, Cushman S W, Wilson C M, Glucose transporter localization in rat skeletal muscle. Autoradiographic study using ATB-[2-3H]BMPA photolabel., Febs Letters, 339(3), 205-8, 21 Feb 1994 Abstract
  • Neufer P D, Dohm G L, Exercise induces a transient increase in transcription of the GLUT-4 gene in skeletal muscle., American Journal of Physiology, 265(6 Pt 1), C1597-603, December 1993 Abstract
  • Kern M, Loomis T A, Tapscott E B, Dohm G L, Increased muscle glucose uptake in response to chronic glyburide treatment is not related to changes in glucose transporter (GLUT4) protein., International Journal of Biochemistry, 25(9), 1257-61, September 1993 Abstract
  • Neufer P D, Carey J O, Dohm G L, Transcriptional regulation of the gene for glucose transporter GLUT4 in skeletal muscle. Effects of diabetes and fasting., Journal of Biological Chemistry, 268(19), 13824-9, 5 Jul 1993 Abstract
  • Houmard J A, Shinebarger M H, Dolan P L, Leggett-Frazier N, Bruner R K, McCammon M R, Israel R G, Dohm G L, Exercise training increases GLUT-4 protein concentration in previously sedentary middle-aged men., American Journal of Physiology, 264(6 Pt 1), E896-901, June 1993 Abstract
  • Dohm G L, Dolan P L, Frisell W R, Dudek R W, Role of transverse tubules in insulin stimulated muscle glucose transport., Journal of Cellular Biochemistry, 52(1), 1-7, May 1993 Abstract
  • Megeney L A, Neufer P D, Dohm G L, Tan M H, Blewett C A, Elder G C, Bonen A, Effects of muscle activity and fiber composition on glucose transport and GLUT-4., American Journal of Physiology, 264(4 Pt 1), E583-93, April 1993 Abstract
  • Sherman W M, Friedman J E, Gao J P, Reed M J, Elton C W, Dohm G L, Glycemia and exercise training alter glucose transport and GLUT4 in the Zucker rat., Medicine and Science In Sports and Exercise, 25(3), 341-8, March 1993 Abstract
  • Houmard J A, Hortobagyi T, Neufer P D, Johns R A, Fraser D D, Israel R G, Dohm G L, Training cessation does not alter GLUT-4 protein levels in human skeletal muscle., Journal of Applied Physiology, 74(2), 776-81, February 1993 Abstract
  • Dolan P L, Tapscott E B, Dorton P J, Dohm G L, Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats., Biochemical Journal, 289 ( Pt 2), 423-6, 15 Jan 1993 Abstract
  • Neufer P D, Shinebarger M H, Dohm G L, Effect of training and detraining on skeletal muscle glucose transporter (GLUT4) content in rats., Canadian Journal of Physiology and Pharmacology, 70(9), 1286-90, September 1992 Abstract
  • Kern M, Dolan P L, Mazzeo R S, Wells J A, Dohm G L, Effect of aging and exercise on GLUT-4 glucose transporters in muscle., American Journal of Physiology, 263(2 Pt 1), E362-7, August 1992 Abstract
  • Pories W J, MacDonald K G Jr, Flickinger E G, Dohm G L, Sinha M K, Barakat H A, May H J, Khazanie P, Swanson M S, Morgan E, et al, Is type II diabetes mellitus (NIDDM) a surgical disease?, Annals of Surgery, 215(6), 633-42; discussion 6, June 1992 Abstract
  • Friedman J E, Dohm G L, Leggett-Frazier N, Elton C W, Tapscott E B, Pories W P, Caro J F, Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4., Journal of Clinical Investigation, 89(2), 701-5, February 1992 Abstract
  • Pories W J, MacDonald K G Jr, Morgan E J, Sinha M K, Dohm G L, Swanson M S, Barakat H A, Khazanie P G, Leggett-Frazier N, Long S D, et al, Surgical treatment of obesity and its effect on diabetes: 10-y follow-up., American Journal of Clinical Nutrition, 55(2 Suppl), 582S-585S, February 1992 Abstract
  • Friedman J E, de Vente J E, Peterson R G, Dohm G L, Altered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa)., American Journal of Physiology, 261(6 Pt 1), E782-8, December 1991 Abstract
  • Houmard J A, Egan P C, Neufer P D, Friedman J E, Wheeler W S, Israel R G, Dohm G L, Elevated skeletal muscle glucose transporter levels in exercise-trained middle-aged men., American Journal of Physiology, 261(4 Pt 1), E437-43, October 1991 Abstract
  • Friedman J E, Dohm G L, Elton C W, Rovira A, Chen J J, Leggett-Frazier N, Atkinson S M Jr, Thomas F T, Long S D, Caro J F, Muscle insulin resistance in uremic humans: glucose transport, glucose transporters, and insulin receptors., American Journal of Physiology, 261(1 Pt 1), E87-94, July 1991 Abstract
  • Friedman J E, Neufer P D, Dohm G L, Regulation of glycogen resynthesis following exercise. Dietary considerations., Sports Medicine, 11(4), 232-43, April 1991 Abstract
  • Dohm G L, Elton C W, Friedman J E, Pilch P F, Pories W J, Atkinson S M Jr, Caro J F, Decreased expression of glucose transporter in muscle from insulin-resistant patients., American Journal of Physiology, 260(3 Pt 1), E459-63, March 1991 Abstract
  • Friedman J E, Dudek R W, Whitehead D S, Downes D L, Frisell W R, Caro J F, Dohm G L, Immunolocalization of glucose transporter GLUT4 within human skeletal muscle., Diabetes, 40(1), 150-4, January 1991 Abstract
  • Dohm G L, Elton C W, Raju M S, Mooney N D, DiMarchi R, Pories W J, Flickinger E G, Atkinson S M Jr, Caro J F, IGF-I--stimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM., Diabetes, 39(9), 1028-32, September 1990 Abstract
  • Kern M, Tapscott E B, Downes D L, Frisell W R, Dohm G L, Insulin resistance induced by high-fat feeding is only partially reversed by exercise training., Pflügers archiv. European Journal of Physiology, 417(1), 79-83, September 1990 Abstract
  • Kern M, Wells J A, Stephens J M, Elton C W, Friedman J E, Tapscott E B, Pekala P H, Dohm G L, Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level., Biochemical Journal, 270(2), 397-400, 1 Sep 1990 Abstract
  • Casla A, Rovira A, Wells J A, Dohm G L, Increased glucose transporter (GLUT4) protein expression in hyperthyroidism., Biochemical and Biophysical Research Communications, 171(1), 182-8, 31 Aug 1990 Abstract
  • Friedman J E, Sherman W M, Reed M J, Elton C W, Dohm G L, Exercise training increases glucose transporter protein GLUT-4 in skeletal muscle of obese Zucker (fa/fa) rats., Febs Letters, 268(1), 13-6, 30 Jul 1990 Abstract
  • Boyd J J, Contreras I, Kern M, Tapscott E B, Downes D L, Frisell W R, Dohm G L, Effect of a high-fat-sucrose diet on in vivo insulin receptor kinase activation., American Journal of Physiology, 259(1 Pt 1), E111-6, July 1990 Abstract
  • Kern M, Tapscott E B, Snider R D, Dohm G L, Differences in glucose transport rates between perfused and in vitro incubated muscles., Hormone and Metabolic Research, 22(7), 366-8, July 1990 Abstract
  • Contreras I, Dohm G L, Abdallah S, Wells J A, Mooney N, Rovira A, Caro J F, The effect of fasting on the activation in vivo of the insulin receptor kinase., Biochemical Journal, 265(3), 887-90, 1 Feb 1990 Abstract
  • Barakat H A, Dohm G L, Shukla N, Marks R H, Kern M, Carpenter J W, Mazzeo R S, Influence of age and exercise training on lipid metabolism in Fischer-344 rats., Journal of Applied Physiology, 67(4), 1638-42, October 1989 Abstract
  • Fushiki T, Wells J A, Tapscott E B, Dohm G L, Changes in glucose transporters in muscle in response to exercise., American Journal of Physiology, 256(5 Pt 1), E580-7, May 1989 Abstract

Profile Details

Last Updated: 11/8/2004

COS Expertise ID #368529
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