Dr. Seth W. Donahue

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Michigan Technological University
College of Engineering
Biomedical Engineering
Assistant ProfessorAppointed: 2001
Department of Orthopaedics

Mailing Address

Department of Biomedical Engineering
312 Chemical Sciences Building
1400 Townsend Drive
Houghton, Michigan 49931
United States

Contact Information

Phone: (906) 487-1729
Fax: (906) 487-1717
swdonahu@mtu.edu
http://www.biomed.mtu.edu/swdonahu/

Qualifications

Post-doctoral fellowship, Pennsylvania State University, Cell Biology, 2001.
Ph.D., University of California, Davis, Biomedical Engineering, 1999.

Expertise and Research Interests

Bone mechanics;
Bone histomorphometry;
Cellular mechanotransduction;
Fluorescent imaging;
Mechanically induced intracellular calcium signaling in bone cells;

Other Expertise

Bone metabolism in hibernating black bears

Future Research

Mechanically induced gene and protein expression in musculoskeletal cells

Industrial Relevance

Mechanotransduction research in bone and cartilage cells is likely to identify cellular targets for the development of novel pharmaceutical therapies for diseases such as osteoporosis and osteoarthritis

Keywords

COS Keywords:

Biomedical Engineering, Bone, Medical or Diagnostic Imaging, Osteoporosis.

Additional Terms:

Bone Mechanics, Fluorescent Imaging, Mechanotransduction.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)

Memberships

American Society of Biomechanics
Biomedical Engineering Society
Orthopaedic Research Society

Honors and Awards

1999-2001, Orthopaedic Research Society Travel Award for the International Sun Valley Hard Tissue Workshop,
1998, Biomedical Engineering Society Travel Award,

Previous Positions

1999-2001, Post-doctoral fellow, M. S. Hershey Medical Center, Medicine, Department of Orthopaedics and Rehabilitation

Publications

  • Hamel AJ, Donahue SW, Sharkey NA, Contributions of active and passive toe flexion to forefoot loading, Clinical Orthopaedics and Related Research, 393, 326-34, 2001
  • Donahue SW, Jacobs CR, and Donahue HJ, Flow-induced calcium oscillations in rat osteoblasts are age, loading frequency, and shear stress dependent, American Journal of Physiology, 281(5), C1635-C1641, 2001
  • Donahue SW, Sharkey NA, Modanlou KA, Sequeira LN, Martin RB, Bone strain and microcracks at stress fracture sites in human metatarsals, Bone, 27(6), 827-33, December 2000 Abstract
  • Donahue SW, Sharkey NA, Strains in the metatarsals during the stance phase of gait: implications for stress fractures, Journal of Bone and Joint Surgery. American Volume, 81(9), 1236-44, September 1999 Abstract
  • Sharkey NA, Donahue SW, Ferris L, Biomechanical consequences of plantar fascial release or rupture during gait. Part II: alterations in forefoot loading, Foot and Ankle International, 20(2), 86-96, February 1999 Abstract
  • Sharkey NA, Ferris L, Donahue SW, Biomechanical consequences of plantar fascial release or rupture during gait: part I--disruptions in longitudinal arch conformation, Foot and Ankle International, 19(12), 812-20, December 1998 Abstract
  • Sharkey NA, Donahue SW, Smith TS, Bay BK, Marder RA, Patellar strain and patellofemoral contact after bone-patellar tendon-bone harvest for anterior cruciate ligament reconstruction, Archives of Physical Medicine and Rehabilitation, 78(3), 256-63, March 1997 Abstract

Profile Details

Last Updated: 2/21/2002

COS Expertise ID #858574
Reference this profile directly: http://myprofile.cos.com/donahue1