David Lee Thomas

powered by
COS Expertise®
Johns Hopkins University
Medicine
Medicine
Infectious Diseases
Johns Hopkins University
School of Medicine
Infectious Diseases
Professor

Mailing Address

J.H. Medical Institutions E. Baltimore
Suite 437 1830 Monument Street
Baltimore, Maryland 21205
United States

Contact Information

Phone: (410) 502-7134
Fax: (410) 614-8488
dthomasa@comcast.net

Qualifications

M.P.H., Johns Hopkins University, 1992.
M.D..

Expertise and Research Interests

Hepatitis C
Hepatitis B
HIV liver disease

Keywords

COS Keywords:

Hepatitis, Infectious Diseases or Agents.

Funding Received

  • National Institutes of Health (NIH): HIV-HCV Coinfection: Antiviral Therapy and Fibrosis, 2,263,000, 2005 to 2010.
  • National Institutes of Health (NIH): Progression of Hepatitis C among IDUs, $3,621,313, 2002 to 2007.
  • National Institutes of Health (NIH): HCV Pathogenesis and Host Genome, 3,600,000, 1999 to 2009.

Publications

  • Thomas DL, Seeff LB (Aug 2005) Natural history of hepatitis C., Clinics in Liver Disease, 9 (3), 383-98, vi Abstract
  • Thio CL, Mosbruger T, Astemborski J, Greer S, Kirk GD, O'Brien SJ, Thomas DL (Jul 2005) Mannose binding lectin genotypes influence recovery from hepatitis B virus infection., Journal of Virology, 79 (14), 9192-6 Abstract
  • Kelleher TB, Mehta SH, Bhaskar R, Sulkowski M, Astemborski J, Thomas DL, Moore RE, Afdhal NH (Jul 2005) Prediction of hepatic fibrosis in HIV/HCV co-infected patients using serum fibrosis markers: the SHASTA index., Journal of Hepatology, 43 (1), 78-84 Abstract
  • Ray SC, Fanning L, Wang XH, Netski DM, Kenny-Walsh E, Thomas DL (Jun 2005) Divergent and convergent evolution after a common-source outbreak of hepatitis C virus., The Journal of Experimental Medicine, 201 (11), 1753-9 Abstract
  • Cox AL, Mosbruger T, Mao Q, Liu Z, Wang XH, Yang HC, Sidney J, Sette A, Pardoll D, Thomas DL, Ray SC (Jun 2005) Cellular immune selection with hepatitis C virus persistence in humans., The Journal of Experimental Medicine, 201 (11), 1741-52 Abstract
  • Strathdee SA, Latka M, Campbell J, O'Driscoll PT, Golub ET, Kapadia F, Pollini RA, Garfein RS, Thomas DL, Hagan H, Study to Reduce Intravenous Exposures Project (Apr 2005) Factors associated with interest in initiating treatment for hepatitis C Virus (HCV) infection among young HCV-infected injection drug users., Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 40 Suppl 5, S304-12 Abstract
  • Cox AL, Netski DM, Mosbruger T, Sherman SG, Strathdee S, Ompad D, Vlahov D, Chien D, Shyamala V, Ray SC, Thomas DL (Apr 2005) Prospective evaluation of community-acquired acute-phase hepatitis C virus infection., Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 40 (7), 951-8 Abstract
  • Sulkowski MS, Mehta SH, Torbenson M, Afdhal NH, Mirel L, Moore RD, Thomas DL (Mar 2005) Hepatic steatosis and antiretroviral drug use among adults coinfected with HIV and hepatitis C virus., Aids (london, England), 19 (6), 585-92 Abstract
  • Hershow RC, O'Driscoll PT, Handelsman E, Pitt J, Hillyer G, Serchuck L, Lu M, Chen KT, Yawetz S, Pacheco S, Davenny K, Adeniyi-Jones S, Thomas DL (Mar 2005) Hepatitis C virus coinfection and HIV load, CD4+ cell percentage, and clinical progression to AIDS or death among HIV-infected women: Women and Infants Transmission Study., Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 40 (6), 859-67 Abstract
  • Mehta SH, Thomas DL, Torbenson M, Brinkley S, Mirel L, Chaisson RE, Moore RD, Sulkowski MS (Jan 2005) The effect of antiretroviral therapy on liver disease among adults with HIV and hepatitis C coinfection., Hepatology (baltimore, Md.), 41 (1), 123-31 Abstract
  • Francis JS, Doherty MC, Lopatin U, Johnston CP, Sinha G, Ross T, Cai M, Hansel NN, Perl T, Ticehurst JR, Carroll K, Thomas DL, Nuermberger E, Bartlett JG (Jan 2005) Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes., Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 40 (1), 100-7 Abstract
  • Mehta SH, Brancati FL, Strathdee SA, Pankow JS, Netski D, Coresh J, Szklo M, Thomas DL, Hepatitis C virus infection and incident type 2 diabetes, Hepatology (baltimore, Md.), 38(1), 50-6, July 2003 Abstract
  • Ogedegbe AE, Thomas DL, Diehl AM, Hyperlactataemia syndromes associated with HIV therapy, The Lancet Infectious Diseases, 3(6), 329-37, June 2003 Abstract
  • Sulkowski MS, Thomas DL, Hepatitis C in the HIV-Infected Person, Annals of Internal Medicine, 138(3), 197-207, February 2003 Abstract
  • Thio CL, Seaberg EC, Skolasky R Jr, Phair J, Visscher B, Munoz A, Thomas DL, Multicenter AIDS Cohort Study, HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS), Lancet, 360(9349), 1921-6, December 2002 Abstract
  • Torbenson M, Thomas DL, Occult hepatitis B, The Lancet Infectious Diseases, 2(8), 479-86, Aug 2002 Abstract
  • Sulkowski MS, Moore RD, Mehta SH, Chaisson RE, Thomas DL, Hepatitis C and progression of HIV disease, Jama : the Journal of the American Medical Association, 288(2), 199-206, July 2002 Abstract
  • Sulkowski MS, Ray SC, Thomas DL, Needlestick transmission of hepatitis C, Jama : the Journal of the American Medical Association, 287(18), 2406-13, May 2002 Abstract
  • Rai R, Wilson LE, Astemborski J, Anania F, Torbenson M, Spoler C, Vlahov D, Strathdee SA, Boitnott J, Nelson KE, Thomas DL, Severity and correlates of liver disease in hepatitis C virus-infected injection drug users, Hepatology (baltimore, Md.), 35(5), 1247-55, May 2002 Abstract
  • Thio CL, Gao X, Goedert JJ, Vlahov D, Nelson KE, Hilgartner MW, O'Brien SJ, Karacki P, Astemborski J, Carrington M, Thomas DL, HLA-Cw*04 and hepatitis C virus persistence, Journal of Virology, 76(10), 4792-7, May 2002 Abstract
  • Streiff MB, Mehta S, Thomas DL, Peripheral blood count abnormalities among patients with hepatitis C in the United States, Hepatology (baltimore, Md.), 35(4), 947-52, April 2002 Abstract
  • Mehta SH, Cox A, Hoover DR, Wang XH, Mao Q, Ray S, Strathdee SA, Vlahov D, Thomas DL, Protection against persistence of hepatitis C, Lancet, 359(9316), 1478-83, April 2002 Abstract
  • Sulkowski MS, Thomas DL, Mehta SH, Chaisson RE, Moore RD, Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections, Hepatology (baltimore, Md.), 35(1), 182-9, January 2002 Abstract
  • Wilson LE, Umemura T, Astemborski J, Ray SC, Alter HJ, Strathdee SA, Vlahov D, Thomas DL, Dynamics of SEN virus infection among injection drug users, The Journal of Infectious Diseases, 184(10), 1315-9, November 2001 Abstract
  • Srinivasan A, Kraus CN, DeShazer D, Becker PM, Dick JD, Spacek L, Bartlett JG, Byrne WR, Thomas DL, Glanders in a military research microbiologist, The New England Journal of Medicine, 345(4), 256-8, July 2001 Abstract
  • Thio CL, Thomas DL, Goedert JJ, Vlahov D, Nelson KE, Hilgartner MW, O'Brien SJ, Karacki P, Marti D, Astemborski J, Carrington M, Racial differences in HLA class II associations with hepatitis C virus outcomes, The Journal of Infectious Diseases, 184(1), 16-21, July 2001 Abstract
  • Mao Q, Ray SC, Laeyendecker O, Ticehurst JR, Strathdee SA, Vlahov D, Thomas DL, Human immunodeficiency virus seroconversion and evolution of the hepatitis C virus quasispecies, Journal of Virology, 75(7), 3259-67, April 2001 Abstract
  • Thomas DL, Rich JD, Schuman P, Smith DK, Astemborski JA, Nolt KR, Klein RS, Multicenter evaluation of hepatitis C RNA levels among female injection drug users, The Journal of Infectious Diseases, 183(6), 973-6, March 2001 Abstract
  • Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL, Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States, Annals of Internal Medicine, 133(8), 592-9, October 2000 Abstract
  • Thomas DL, Astemborski J, Rai RM, Anania FA, Schaeffer M, Galai N, Nolt K, Nelson KE, Strathdee SA, Johnson L, Laeyendecker O, Boitnott J, Wilson LE, Vlahov D, The natural history of hepatitis C virus infection: host, viral, and environmental factors, Jama : the Journal of the American Medical Association, 284(4), 450-6, July 2000 Abstract
  • Ray SC, Mao Q, Lanford RE, Bassett S, Laeyendecker O, Wang YM, Thomas DL, Hypervariable region 1 sequence stability during hepatitis C virus replication in chimpanzees., Journal of Virology, 74(7), 3058-66, 2000 Abstract
  • Thomas DL, Astemborski J, Vlahov D, Strathdee SA, Ray SC, Nelson KE, Galai N, Nolt KR, Laeyendecker O, Todd JA, Determinants of the quantity of hepatitis C virus RNA., Journal of Infectious Diseases, 181(3), 844-51, 2000 Abstract
  • Sulkowski MS, Thomas DL, Chaisson RE, Moore RD, Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection., JAMA, 283(1), 74-80, 5 2000 Abstract
  • Ray S C, Wang Y M, Laeyendecker O, Ticehurst J R, Villano S A, Thomas D L, Acute hepatitis C virus structural gene sequences as predictors of persistent viremia: hypervariable region 1 as a decoy, JOURNAL OF VIROLOGY, 73(4), 2938-46, 1999 Abstract
  • Thio C L, Carrington M, Marti D, OBrien S J, Vlahov D, Nelson K E, Astemborski J, Thomas D L, Class II HLA alleles and hepatitis B virus persistence in African Americans, JOURNAL OF INFECTIOUS DISEASES, 179(4), 1004-6, 1999 Abstract
  • Villano S A, Vlahov D, Nelson K E, Cohn S, Thomas D L, Persistence of viremia and the importance of long-term follow-up after acute hepatitis C infection, HEPATOLOGY, 29(3), 908-14, 1999 Abstract
  • Inglesby T V, Rai R, Astemborski J, Gruskin L, Nelson K E, Vlahov D, Thomas D L, A prospective, community-based evaluation of liver enzymes in individuals with hepatitis C after drug use, HEPATOLOGY, 29(2), 590-6, 1999 Abstract
  • Wang Y M, Ray S C, Laeyendecker O, Ticehurst J R, Thomas D L, Assessment of hepatitis C virus sequence complexity by electrophoretic mobilities of both single-and double-stranded DNAs, JOURNAL OF CLINICAL MICROBIOLOGY, 36(10), 2982-9, 1998 Abstract
  • Thomas D L, Villano S A, Riester K A, Hershow R, Mofenson L M, Landesman S H, Hollinger F B, Davenny K, Riley L, Diaz C, Tang H B, Quinn T C, Perinatal transmission of hepatitis C virus from human immunodeficiency virus type 1-infected mothers Women and Infants Transmission Study, JOURNAL OF INFECTIOUS DISEASES, 177(6), 1480-8, 1998 Abstract
  • Thomas D L, Vlahov D, Alter H J, Hunt J C, Marshall R, Astemborski J, Nelson K E, Association of antibody to GB virus C (hepatitis G virus) with viral clearance and protection from reinfection, JOURNAL OF INFECTIOUS DISEASES, 177(3), 539-42, 1998 Abstract
  • Garfein R S, Doherty M C, Monterroso E R, Thomas D L, Nelson K E, Vlahov D, Prevalence and incidence of hepatitis C virus infection among young adult injection drug users, JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 18 Suppl 1(1077-9450), S11-9, 1998 Abstract
  • Villano S A, Vlahov D, Nelson K E, Lyles C M, Cohn S, Thomas D L, Incidence and risk factors for hepatitis C among injection drug users in Baltimore, Maryland, JOURNAL OF CLINICAL MICROBIOLOGY, 35(12), 3274-7, 1997 Abstract
  • Erbelding E J, Vlahov D, Nelson K E, Rompalo A M, Cohn S, Sanchez P, Quinn T C, Brathwaite W, Thomas D L, Syphilis serology in human immunodeficiency virus infection: evidence for false-negative fluorescent treponemal testing see comments, JOURNAL OF INFECTIOUS DISEASES, 176(5), 1397-400, 1997 Abstract
  • Thomas D L, Nakatsuji Y, Shih J W, Alter H J, Nelson K E, Astemborski J A, Lyles C M, Vlahov D, Persistence and clinical significance of hepatitis G virus infections in injecting drug users, JOURNAL OF INFECTIOUS DISEASES, 176(3), 586-92, 1997 Abstract
  • Villano S A, Nelson K E, Vlahov D, Purcell R H, Saah A J, Thomas D L, Hepatitis A among homosexual men and injection drug users: more evidence for vaccination, CLINICAL INFECTIOUS DISEASES, 25(3), 726-8, 1997 Abstract
  • Hershow R C, Riester K A, Lew J, Quinn T C, Mofenson L M, Davenny K, Landesman S, Cotton D, Hanson I C, Hillyer G V, Tang H B, Thomas D L, Increased vertical transmission of human immunodeficiency virus from hepatitis C virus-coinfected mothers Women and Infants Transmission Study, JOURNAL OF INFECTIOUS DISEASES, 176(2), 414-20, 1997 Abstract
  • Thomas D L, Yarbough P O, Vlahov D, Tsarev S A, Nelson K E, Saah A J, Purcell R H, Seroreactivity to hepatitis E virus in areas where the disease is not endemic, JOURNAL OF CLINICAL MICROBIOLOGY, 35(5), 1244-7, 1997 Abstract
  • Thomas D L, Shih J W, Alter H J, Vlahov D, Cohn S, Hoover D R, Cheung L, Nelson K E, Effect of human immunodeficiency virus on hepatitis C virus infection among injecting drug users, JOURNAL OF INFECTIOUS DISEASES, 174(4), 690-5, 1996 Abstract
  • Miskovsky E P, Carrella A V, Gutekunst K, Sun C A, Quinn T C, Thomas D L, Clinical characterization of a competitive PCR assay for quantitative testing of hepatitis C virus, JOURNAL OF CLINICAL MICROBIOLOGY, 34(8), 1975-9, 1996 Abstract
  • Thomas D L, Gruninger S E, Siew C, Joy E D, Quinn T C, Occupational risk of hepatitis C infections among general dentists and oral surgeons in North America, AMERICAN JOURNAL OF MEDICINE, 100(1), 41-5, 1996 Abstract
  • Fairbank A C, Thomas D, Cunningham B, Curtis M, Jinnah R H, Stability of reamed and unreamed intramedullary tibial nails: a biomechanical study, INJURY, 26(7), 483-5, 1995 Abstract
  • Thomas D L, Vlahov D, Solomon L, Cohn S, Taylor E, Garfein R, Nelson K E, Correlates of hepatitis C virus infections among injection drug users, MEDICINE, 74(4), 212-20, 1995 Abstract
  • Thomas D L, Zenilman J M, Alter H J, Shih J W, Galai N, Carella A V, Quinn T C, Sexual transmission of hepatitis C virus among patients attending sexually transmitted diseases clinics in Baltimore--an analysis of 309 sex partnerships, JOURNAL OF INFECTIOUS DISEASES, 171(4), 768-75, 1995 Abstract
  • Thomas D L, Rompalo A M, Zenilman J, Hoover D, Hook E W, Quinn T C, Association of hepatitis C virus infection with false-positive tests for syphilis, JOURNAL OF INFECTIOUS DISEASES, 170(6), 1579-81, 1994 Abstract
  • Thomas D L, Mahley R W, Badur S, Palaoglu E, Quinn T C, The epidemiology of hepatitis C in Turkey, INFECTION, 22(6), 411-4, 1994 Abstract
  • Thomas D L, Cannon R O, Shapiro C N, Hook E W, Alter M J, Quinn T C, Hepatitis C, hepatitis B, and human immunodeficiency virus infections among non-intravenous drug-using patients attending clinics for sexually transmitted diseases, JOURNAL OF INFECTIOUS DISEASES, 169(5), 990-5, 1994 Abstract
  • Thomas D L, Quinn T C, The course of non-A, non-B hepatitis unrelated to transfusion letter; comment, ANNALS OF INTERNAL MEDICINE, 120(2), 171-2, 15 1994 Abstract
  • Thomas D L, Quinn T C, Serologic testing for sexually transmitted diseases, INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 7(4), 793-824, 1993 Abstract
  • Thomas D L, Mundy L M, Tucker P C, Hot tub legionellosis Legionnaires' disease and Pontiac fever after a point-source exposure to Legionella pneumophila, ARCHIVES OF INTERNAL MEDICINE, 153(22), 2597-9, 22 1993 Abstract
  • Thomas D L, Factor S H, Kelen G D, Washington A S, Taylor E Jr, Quinn T C, Viral hepatitis in health care personnel at The Johns Hopkins Hospital The seroprevalence of and risk factors for hepatitis B virus and hepatitis C virus infection see comments, ARCHIVES OF INTERNAL MEDICINE, 153(14), 1705-12, 26 1993 Abstract
  • Thomas D L, Mahley R W, Badur S, Palaoglu K E, Quinn T C, Epidemiology of hepatitis E virus infection in Turkey see comments, LANCET, 341(8860), 1561-2, 19 1993 Abstract
  • Thomas D, Kendig N, Tension pneumocephalus: acute neurological deterioration associated with pleocytosis of the CSF, CLINICAL INFECTIOUS DISEASES, 16(5), 703-5, 1993 Abstract

Profile Details

Last Updated: 10/24/2007

COS Expertise ID #569168
Reference this profile directly: http://myprofile.cos.com/dthoma12