Denise von Muhlen

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University of California, San Diego
Assistant Adjunct Professor

Mailing Address

9500 Gilman Drive
La Jolla, California 92093-0631C
United States

Contact Information

Phone: (858) 534-3721
dvonmuhlen@ucsd.edu

Qualifications

Ph.D., Federal University of Rio Grande do Sul, Endocrinology, 2000.
M.P.H., Federal University of Rio Grande do Sul, Epidemiology, 1992.
M.D., Federal University of Rio Grande do Sul, 1978.

Expertise and Research Interests

Epidemiology of Aging
Women's Health
Genetic Epidemiology

Keywords

COS Keywords:

Endocrinology, Epidemiology, Genetics, Gerontology, Menopause, Women's Health.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
Portuguese: (Fluent, Fluent, Fluent)
Spanish: (Functional, Basic, Basic)

Memberships

American Society for Bone and Mineral Research
Endocrine Society
North American Menopause Society

Funding Received

  • Procter and Gamble: Genetic polymorphism and sex hormones as predictors of osteoportic fractures in older men, 2007 to 2008.
  • NIH/NIA: CVD Predictors of Cognitive Function Trajectory over 20 Years, 2006 to 2009.
  • National Institutes of Health (NIH): Gender Differences in Bone Loss and Incident Fractures, 2003 to 2007.
  • National Institutes of Health (NIH): DHEA Replacement in Healthy Older Men and Women, 2000 to 2007.

Publications

  • von Mühlen D, Laughlin GA, Kritz-Silverstein D, Bergstron J, Bettencourt R (2008) Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults: the DAWN trial., Osteoporosis International, In Press
  • Jassal S, von Mühlen D, Barrett-Connor E (2007) Measures of renal function, BMD, bone loss, and osteoporotic fracture in older adults: the Rancho Bernardo study, Journal of Bone and Mineral Research, 22 (2), 203-210
  • Krentz AJ, von Mühlen D, Barrett-Connor E (2007) Searching for polycystic ovary syndrome in postmenopausal women: evidence of a dose-effect association with prevalent cardiovascular disease, Menopause, 14 (2), 284-292
  • Trone D, Kritz-Silvertein D, von Mühlen D, Wingard D, Barrett-Connor E (2007) Is Radiographic Vertebral Fracture a Risk Factor for Mortality?, American Journal of Epidemiology, 166 (01), 1191-1197
  • von Mühlen D, Safii S, Jassal S, Svartberg J, Barrett-Connor E (2007) Associations between the Metabolic Syndrome and Bone Health in Older Men and Women: The Rancho Bernardo Study, Osteoporosis International, 18 (10), 1337-1344
  • Reis J, von Mühlen D, Kritz-Silverstein D, Wingard DL, Barrett-Connor E (2007) Vitamin d, parathyroid hormone levels, and the prevalence of metabolic syndrome in community-dwelling older adults, Diabetes Care, 30 (6), 1549-1555
  • Nasmuz S, von Mühlen D, Garland C, Barrett-Connor E (2006) Serum 25-hydroxyvitamin D, parathyroid hormone, and bone mineral density in men: The Rancho Bernardo Cohort, Osteoporosis International, In Press
  • von Mühlen D, Laughlin GA, Kritz-Silverstein D, Barrett-Connor E (2006) The Dehydroepiandrosterone And WellNess (DAWN) Study: Research Design and Methods, Journal of Contemporary Clinical Trials, In Press
  • Svartberg J, von Mühlen D, Mathiesen E, Joakimsen O, Bonaa KH, Stensland-Bugge E (2006) Low testosterone levels are associated with carotid atherosclerosis in men, Journal of Internal Medicine, 259, 576-582
  • Hongsdusit N, von Mühlen D, Barrett-Connor E (2006) A comparison between peripheral BMD and central BMD measurements in the prediction of spine fractures in men, Osteoporosis International, 17 (6), 872-7
  • Weiss LA, Barrett-Connor E, von Mühlen D, Clark P (2005) Leptin predicts bone density and bone resorption in older women but not older men: The Rancho Bernardo Study, Journal of Bone and Mineral Research, 21 (5), 758-64
  • Jassal S, von Mühlen D, Barrett-Connor E, Rosen CJ (2005) Serum insulin-like growth factor binding protein-1 levels and bone mineral density in older adults: the Rancho Bernardo Study, Osteoporosis International, 16 (12), 1948-54
  • von Mühlen DG, Greendale GA, Garland CF, Wan L, Barrett-Connor E (2005) Vitamin D, parathyroid hormone levels and bone mineral density in community-dwelling older women: The Rancho Bernardo Study, Osteoporosis International, 16 (12), 1721-1726
  • Richard E, von Mühlen DG, Barrett-Connor E, Alcaraz J, Davis R, McCarthy JJ (2005) Modification of the effects of estrogen therapy on HDL cholesterol levels by polymorphisms of the HDL-C receptor, SR-BI: The Rancho Bernardo Study, Atherosclerosis, 180 (2), 255-262
  • Weiss LA, Barrett-Connor E, von Mühlen D (2005) Ratio of N-6 to N-3 Fatty Acids and Bone Mineral Density in Older Adults: the Rancho Bernardo Study, Am J Clin Nutr, 81 (4), 934-8
  • Svartberg J, von Mühlen D, Sundsfjord J, Bønaa KH, Jorde R (2004) Waist circumference and testosterone levels in community dwelling men. The Tromsø study, European Journal of Epidemiology, 19, 657-663
  • Kritz-Silverstein D, von Mühlen D, Ganiats T, Barrett-Connor E (2004) Hysterectomy status, estrogen use and quality of life in older women: The Rancho Bernardo Study, Quality of Life Research, 13 (1), 55-62
  • Kritz-Silverstein D, von Mühlen D, Barrett-Connor E (2004) Hysterectomy and Oophorectomy are unrelated to Bone Loss in Older Women, Maturitas, 47, 61-69
  • Svartberg J, von Mühlen D, Barrett-Connor E, Sundsfjord J, Jorde R (2004) Associations of endogenous testosterone with blood pressure and left ventricular mass in men. The Tromso Study, European Journal of Endocrinology, 150 (1), 65-71
  • Schneider DL, von Mühlen D, Barrett-Connor E (2004) Kyphosis does not equal vertebral fractures: The Rancho Bernardo Study, American Journal of Rheumatology, 4, 747-52
  • Kritz-Silverstein D, von Mühlen D, Barrett-Connor E (2003) Isoflavones and cognitive function in older women: the Soy and Postmenopausal Health In Aging (SOPHIA) Study, Menopause, 10 (3), 196-202
  • Barrett-Connor E, von Mühlen D (2003) Apolipoprotein E gene and serum testosterone and dehydroepiandrosterone levels in postmenopausal women, European Journal of Endocrinology, 148, 487-488
  • von Mühlen D, Langer RD, Barrett-Connor E (2003) Gender and time differences in the association between non-high density lipoprotein cholesterol and cardiovascular mortality in older adults: The Rancho Bernardo Study, The American Journal of Cardiology, 91, 1311-1315
  • von Mühlen DG,, Barrett-Connor E, Kritz-Silverstein D (2002) Apolipoprotein E genotype and response of lipid levels to postmenopausal estrogen use, Artheriosclerosis, 161, 209-214
  • von Mühlen DG, Morton D, von Mühlen CA, Barrett-Connor E (01 Jan 2002) Postmenopausal estrogen and risk of clinical osteoarthritis at the hip, hand and knee in older women, Journal of WomenÂ's Health, 11, 511-518
  • von Mühlen DG, Barrett-Connor E, Schneider D, Morin PParry P (2001) Osteoporosis and Apolipropotein E Genotype in Older Adults: The Rancho Bernardo Study, Osteoporosis International, 12, 332-335
  • von Mühlen DG, Soroko S, Kritz-Silverstein D, Barrett-Connor E (2000) Vasomotor Symptoms are not associated with Low Bone Density in Older Women, Journal of Women's Health, 9, 505-511
  • Kritz-Silverstein D, von Mühlen DG, Barrett-Connor E (2000) Prevalence and Clustering of Menopausal Symptoms in Older Women by Hysterectomy and Oophorectomy Status, Journal of Women's Health & Gender-Based Medicine, 9, 747-755
  • Laughlin G, Barrett-Connor E, Kritz-Silverstein D, von Mühlen DG (2000) Hysterectomy, Oophorectomy, and Endogenous Sex Steroid Hormone Levels in Older Women: The Rancho Bernardo Study, Journal of Clinical Endocrinology and Metabolism (85), 645-651
  • Barrett-Connor E, Mueller J, von Mühlen DG, Laughlin G, Schneider D, Sartoris D (2000) Low levels of estradiol are associated with vertebral fractures in older men, but not women: The Rancho Bernardo Study, Journal of Clinical Endocrinology and Metabolism, 85, 219-223
  • Barrett-Connor EL, von Mühlen DG, Laughlin G, Kripke A (1999) Endogenous Levels of Dehydroepiandrosterone Sulfate, but Not Other Sex Hormones, Are Associated with Depressed Mood in Older Women: The Rancho Bernardo Study, Journal of The American Geriatrics Society (47), 685-691
  • von Mühlen D, Lunde AV, Barrett-Connor EL (1999) Evaluation of Simple Calculated Osteoporosis Risk Estimation in Older Caucasian Women (SCORE): The Rancho Bernardo Study, Osteoporosis International (10), 79-84
  • Barrett-Connor EL, von Mühlen DG, Laughlin G, Kripke A (1999) Endogenous Levels of Dehydroepiandrosterone Sulfate, but Not Other Sex Hormones, Are Associated with Depressed Mood in Older Women: The Rancho Bernardo Study, Journal of The American Geriatrics Society (47), 685-691
  • Barrett-Connor EL, von Mühlen DG, Kritz-Silverstein D (1999) Bioavailable Testosterone and Depressed Mood in Older Men: The Rancho Bernardo Study, Journal of Clinical Endocrinology and Metabolism (84), 573-577
  • von Mühlen D, Kritz-Silverstein D, Barrett-Connor E (1995) A community-based study of menopause symptoms and estrogen replacement in older women, Maturitas (22), 71-78

Profile Details

Last Updated: 3/24/2008

COS Expertise ID #1132741
Reference this profile directly: http://myprofile.cos.com/dvonmuhle