Dr. Dario J. Englot

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University of California, San Francisco
School of Medicine
Neurological Surgery
ResidentAppointed: 2010
Professional Headshot of Dario J. Englot

Mailing Address

Dept. of Neurological Surgery
University of California, San Francisco
505 Parnassus Avenue M-779
San Francisco, California 94143-0112
United States

Contact Information

englot@gmail.com

Qualifications

M.D., Yale University, 2010.
Ph.D., Yale University, Neuroscience, 2009.
M.Phil., Yale University, Neuroscience, 2007.
B.S., University of Scranton, Neuroscience (minors: Biochemistry and Philosophy), Summa cum laude, 2003.

Expertise and Research Interests

I completed my Ph.D. research in the laboratory of Hal Blumenfeld, M.D., Ph.D. at Yale, studying the widespread neocortical effects of limbic seizures in temporal lobe epilepsy. We utilized electrophysiological, neuroimaging, and behavioral techniques to study seizures in animal models. Afterwards, I completed a post-doctoral project in Dr. Blumenfeld's lab, correlating intracranial electroencephalography (EEG) signals and consciousness during seizures in temporal lobe epilepsy patients.

Future Research

I am interested in various areas of basic neuroscience and clinical neurosurgery, including functional neuroimaging, epilepsy, and stereotactic functional neurosurgery for movement and psychiatric disorders.

Keywords

COS Keywords:

Electrophysiology, Epilepsy, Neuroscience, Neurosurgery.

Additional Terms:

EEG, FMRI, Functional Neurosurgery, Neuroimaging.

Memberships

American Association of Neurological Surgeons
American College of Surgeons
American Epilepsy Society
American Medical Association
California Medical Association
Congress of Neurological Surgeons
San Francisco Medical Society
Society for Neuroscience

Honors and Awards

2009, Travel Award, How To Combine Clinical and Research Careers in Neuroscience Symposium, National Institutes of Neurological Disorders and Stroke (NINDS)
2008, Educational Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
2008, Academic Scholarship, National Italian American Foundation (NIAF)
2006, Travel Award, American Academy of Neurology (AAN)
2003, National Honor Society for Philosophy, Phi Sigma Tau
2003, Top Ranked Graduate (by GPA) in College of Arts and Sciences, University of Scranton
2003, Excellence in Neuroscience Award, University of Scranton
2002-2003, Loughran-Peters Scholarship, University of Scranton
2002-2003, Thomas J. and Frank F. Shevlin Scholarship, University of Scranton
2002, Pre-Medical Honor Society, Alpha Epsilon Delta
2002, National Jesuit Honor Society, Alpha Sigma Nu
2002, National Biological Honor Society, Beta Beta Beta
2002, National Honorary Chemical Society, Phi Lambda Upsilon
2001-2002, Presidential Honors List, University of Scranton
1999-2003, Loyola Scholarship, University of Scranton
1999, Academic Scholarship, Kiwanis International
1999-2003, Dean's List, University of Scranton
1999-2003, Honor's Program, University of Scranton

Previous Positions

2003-2010, M.D./Ph.D. student and post-doctoral research, Yale University, School of Medicine, Neurology
2002-2010, Instructor, The Princeton Review, Chemistry
2001-2002, Research Assistant, University of Texas Health Science Center at Houston, Integrative Biology

Funding Received

  • National Institutes of Health (NIH): Ruth L. Kirschstein National Research Service Award (NRSA) for Individual Predoctoral MD/PhD Fellows (F30), 2007 to 2010.
  • Epilepsy Foundation of America (EFA): Predoctoral Research Fellowship (declined due to concurrent funds), 2007 to 2007.
  • National Institutes of Health (NIH) and Yale University: Medical Scientist Training Program (MSTP), 2003 to 2010.

Publications

  • Englot DJ, Laurans MS, Abbed K, Bulsara KR (Jun 2010) Removal of nail penetrating the basilar artery., Neurosurgical review Abstract
  • Santoro B, Lee JY, Englot DJ, Gildersleeve S, Piskorowski RA, Siegelbaum SA, Winawer MR, Blumenfeld H (Apr 2010) Increased seizure severity and seizure-related death in mice lacking HCN1 channels., Epilepsia Abstract
  • Englot DJ, Yang L, Hamid H, Danielson N, Bai X, Marfeo A, Yu L, Gordon A, Purcaro MJ, Motelow JE, Agarwal R, Ellens DJ, Golomb JD, Shamy MCF, Vives K, Spencer DD, Spencer SS, Schevon C, Zaveri HP, Blumenfeld H (2010) Ictal neocortical slow rhythms and loss of consciousness in temporal lobe epilepsy patients, , , Society for Neuroscience (SFN), San Diego, CA
  • Englot DJ, Yang L, Hamid H, Danielson N, Bai X, Marfeo A, Yu L, Gordon A, Purcaro MJ, Motelow JE, Agarwal R, Ellens DJ, Golomb JD, Shamy MCF, Zhang H, Carlson C, Doyle W, Devinsky O, Vives K, Spencer DD, Spencer SS, Schevon C, Zaveri HP, Blumenfeld H (2010) Ictal neocortical slow activity and impaired consciousness in temporal lobe epilepsy, , , American Epilepsy Society (AES), San Antonio, TX
  • Motelow JE, Mishra AM, Englot DJ, Sanganahalli BG, Kurman K, Hyder F, Blumenfeld H (2010) Neocortical dysfunction is associated with subcortical network changes in limbic seizures: Investigations in a rodent model with high field BOLD fMRI, , , Society for Neuroscience (SFN), San Diego, CA
  • Motelow JE, Mishra AM, Englot DJ, Sanganahalli BG, Kurman K, Hyder F, Blumenfeld H (2010) Cortical and subcortical network dysfunction in limbic seizures: high field BOLD fMRI in a rodent complex partial seizure model, , , American Epilepsy Society (AES), San Antonio, TX
  • Owuor K, Harel NY, Englot DJ, Hisama F, Blumenfeld H, Strittmatter SM (Dec 2009) LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology., Molecular and cellular neurosciences, 42 (4), 448-57 Abstract
  • Englot DJ, Modi B, Mishra AM, Desalvo M, Hyder F, Blumenfeld H (Oct 2009) Cortical deactivation induced by subcortical network dysfunction in limbic seizures, Journal of Neuroscience, 29 (41), 13006-18 Abstract
  • Ellens DJ, Hong E, Giblin K, Singleton MJ, Bashyal C, Englot DJ, Mishra AM, Blumenfeld H (Jul 2009) Development of spike-wave seizures in C3H/HeJ mice, Epilepsy Research, 85 (1), 53-9 Abstract
  • Heida JG, Englot DJ, Sacktor TC, Blumenfeld H, Moshé SL (Apr 2009) Separating kindling and LTP: lessons from studies of PKM zeta in developing and adult rats, Neuroscience Letters, 453 (3), 229-32 Abstract
  • Kunjilwar KK, Fishman HM, Englot DJ, O'Neil RG, Walters ET (Mar 2009) Long-lasting hyperexcitability induced by depolarization in the absence of detectable Ca2+ signals, Journal of Neurophysiology, 101 (3), 1351-60 Abstract
  • Englot DJ, Blumenfeld H (2009) Consciousness and epilepsy: Why are complex-partial seizures complex?, Progress in Brain Research, 177, 147-70 Abstract
  • Englot DJ (2009) Partial Seizures and Consciousness: Insights From Rodent Models (a Ph.D. dissertation), Seattle, WA, Amazon, ISBN=1441452958
  • Englot DJ, Spann M (2009) Neuropsychology and Neurology, Practical Guide to Neuropsychological Testing for Patients, Practitioners, and Other Professionals (Ed: Arzubi E, Mambrino E), New York, NY, Springer Publishing Company, In Press (bookchapter)
  • Englot DJ, Blumenfeld H (2009) Functional MRI in basic epilepsy research, Encyclopedia of Basic Epilepsy Research (Ed: Schwartzkroin PA), London, UK, Elsevier B.V. (bookchapter)
  • Englot DJ, Modi B, Mishra AM, DeSalvo M, Hyder F, Blumenfeld H (2009) Septal activation, neocortical deactivation, and diminished behavior during limbic seizures in rats, Society for Neuroscience (SFN), Chicago, IL
  • Englot DJ, Modi B, Mishra AM, DeSalvo M, Hyder F, Blumenfeld H (2009) Involvement of the lateral septum in cortical deactivation during limbic seizures in rats, American Epilepsy Society (AES), Boston, MA
  • Englot DJ, Mishra AM, Mansuripur PK, Herman P, Hyder F, Blumenfeld H (Sep 2008) Remote effects of focal hippocampal seizures on the rat neocortex, Journal of Neuroscience, 28 (36), 9066-81 Abstract
  • Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR (Mar 2008) Early treatment suppresses the development of spike-wave epilepsy in a rat model, Epilepsia, 49 (3), 400-9 Abstract
  • Santoro B, Lee J, Seal S, Englot DJ, Piskorowski R, Siegelbaum S, Winawer M, Blumenfeld H (2008) Neurological phenotype and increased seizure susceptibility of HCN1 knock-out mice, American Epilepsy Society (AES), Seattle, WA
  • Englot DJ, Mishra AM, Purcaro M, Herman P, Hyder F, Blumenfeld H (2008) Simultaneous fMRI and electrophysiology during intracerebral stimulation of partial seizures in rats, International Society for Magnetic Resonance in Medicine (ISMRM), Toronto, ON
  • Englot DJ, Mishra AM, Purcaro M, Herman P, Hyder F, Blumenfeld H (2008) Negative BOLD and decreased metabolism in the rat neocortex during partial limbic seizures, American Epilepsy Society (AES), Seattle, WA
  • Englot DJ, Mishra AM, Purcaro M, Herman P, Hyder F, Blumenfeld H (2008) Remote neocortical effects of partial temporal lobe seizures in rats, Society for Neuroscience (SFN), Washington, DC
  • Englot DJ, Blumenfeld H (2007) Neocortical slowing and thalamic involvement during limbic seizures in rats, American Epilepsy Society (AES), Philadelphia, PA
  • Englot DJ, Blumenfeld H (2007) Ictal slowing and decreased cerebral blood flow in the rat neocortex during limbic seizures, Society for Neuroscience (SFN), San Diego, CA
  • Schridde U, Khubchandani M, Sanganahalli BG, Englot DJ, Hyder F, Blumenfeld H (2006) Hippocampal neuronal activity increases but BOLD fMRI signal decreases in a rodent tonic-clonic seizure model, American Epilepsy Society (AES), San Diego, CA
  • Schridde U, Khubchandani M, Sanganahalli BG, Englot DJ, Hyder F, Blumenfeld H (2006) Combined fMRI and neurophysiological recordings reveal a local dissociation between the BOLD response, cerebral blood flow and neuronal activity in a tonic-clonic seizure model, Society for Neuroscience (SFN), Atlanta, GA
  • Phadke A, Rice T, Khera DS, Klein JP, Mission J, Nersesyan H, Agarwal RK, Levin AR, Englot DJ, Schridde U, Waxman SG, Blumenfeld H (2006) Blockade of activity-dependent plasticity in sodium and HCN1 channel expression is associated with blockade of epilepsy development, Society for Neuroscience (SFN), Atlanta, GA
  • Englot DJ, Schridde U, Blumenfeld H (2006) Ictal neocortical slowing in a rodent model of limbic seizures, American Epilepsy Society (AES), San Diego, CA
  • Weragoda RMS, Englot DJ, Walters ET (2003) Induction of long-term hyperexcitability of Aplysia sensory neuron axons by nerve depolarization requires local protein synthesis but not extracellular calcium, Society for Neuroscience (SFN), Washington, DC
  • Dickneider TA, Englot DJ, Arrigo RJ, Gualtieri DS, Todd MA (2002) Peer group learning in organic chemistry: Start to finish, American Chemical Society (ACS), Orlando, FL

Profile Details

Last Verified: 8/5/2010

COS Expertise ID #1346609
Reference this profile directly: http://myprofile.cos.com/englot