Dr. Eberhard E. Fetz

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University of Washington
School of Medicine
Physiology and Biophysics
ProfessorAppointed: 1980
Washington National Primate Research Center
Neuroscience
Core StaffAppointed: 1969
Professional Headshot of Eberhard E. Fetz

Mailing Address

Department of Physiology and Biophysics
University of Washington
Seattle, Washington 98195-7290
United States

Contact Information

Phone: (206) 543-4839
Fax: (206) 685-8606
fetz@u.washington.edu
http://depts.washington.edu/pbiopage/people_fac_page.php?fac_ID=12

Qualifications

Ph.D., Massachusetts Institute of Technology, Physics, 1967.
B.S., Rensselaer Polytechnic Institute, Physics, 1961.

Expertise and Research Interests

We are currently developing an implantable recurrent brain-computer interface that records neural activity and delivered activity-dependent stimuli at sites in brain, spinal cord or muscles.

Other Expertise

Private pilot
Scuba diving
Collage art

Keywords

COS Keywords:

Brain, Central Nervous System, Nervous System, Neurobiology, Physiology, Primatology, Vertebrate Physiology.

Additional Terms:

Brain, Central Nervous System, Motor, Muscle, Nervous System, Neurobiology, Peripheral Nervous System, Physiology.

Languages

(Reading, Writing, Speaking)

German: (Fluent, Functional, Fluent)
Russian: (Basic, Basic, Basic)

Memberships

American Association for the Advancement of Science
American Physiological Society
International Brain Research Organization
Neural Control of Movement
Sigma Xi
Society for Neuroscience

Honors and Awards

2004-2005, Fellow, Wissenschaftskolleg zu Berlin, Berlin
2002-2002, Visiting Professor, College de France, College de France, Paris, neuroscience
1985-1986, NSF US-Japan Cooperative Science Program Award, National Science Foundation, Kyoto Prefectural University, neuroscience
1977-1978, Faculty Scholar Award, Josiah Macy Foundation, Harvard and University of Goteborg, neurophysiology
1970-1975, Teacher-Investigator Award, NINDS, University of Washington, Physiology and Neurological Surgery

Funding Received

  • Christopher and Dana Reeve Foundation: Cortical control of intraspinal stimulation, 2008 to 2010.
  • Life Sciences Discovery Fund: Development of recurrent implantable brain-computer interfaces for clinical applications, 2008 to 2011.
  • NIH and ITHS: Implantable recurrent brain-computer interfaces for therapeutic applications, 2008 to 2010.
  • National Institutes of Health (NIH): Neural Control of Muscle Activity (Javitz Award), 1974 to 2012.

Publications

  • Miller, K. (2009) Decoupling the cortical power spectrum reveals real-time representation of individual finger movements in humans, Journal of Neuroscience, 29 (3132), 3137
  • Seki, K. (2009) Task-dependent modulation of primary afferent depolarization in cervical spinal cord of monkeys performing an instructed delay task, Journal of Neurophysiology, In Press
  • Kipke, D. (2008) Advanced neurotechnologies for chronic neural interfaces: new horizons and clinical opportunities, Journal of Neuroscience, 28 (11830), 11838
  • Moritz, C.T. (2008) Direct control of paralyzed muscles by cortical neurons, Nature, 456 (639), 642
  • Moritz, C.T., Lucas, T.H., Perlmutter, S.I., Fetz, E.E. (2007) Output effects evoked by microstimulation of cervical spinal cord in sedated monkeys -- implications for neuroprosthetic applications, Journal of Neurophysiology, 97, 110-120
  • Jackson, A, Mavoori, J., Fetz, E.E. (2007) Correlations between motor cortex cells and muscles during a trained task, free behavior and natural sleep in the macaque monkey, Journal of Neurophysiology, 97, 360-374
  • Fetz, E.E (2007) Volitional control of neural activity: implications for brain-computer interfaces., Journal of Physiology (Lond.), 579 (3), 571-579
  • Jackson, A., Fetz, E.E. (2007) A compact moveable microwire array for long-term chronic unit recording in cerebral cortex of primates, Journal of Neurophysiology, 98, 3109-3118
  • Jackson, A., Moritz, C.T., Mavoori, J., Lucas, T.H., Fetz, E.E. (2006) The Neurochip BCI: Towards a neural prosthetic for upper limb function, IEEE Trans. Neural Systems and Rehabilitation Engineering, 14, 187-190
  • Baker, S.N, Chiu, M., Fetz E.E., (2006) Afferent encoding of central oscillations in the monkey arm, Journal of Neurophysiology, 95, 3904-3910
  • Jackson, A., Baker, S.N., Fetz E.E. (2006) Tests for presynaptic modulation of corticospinal terminals from peripheral afferents and the pyramidal tract in the macaque monkey, Journal of Physiology, 573.1, 107-120
  • Jackson, A, Mavoori, J, Fetz, E.E. (2006) Long-term motor cortex plasticity induced by an electronic neural implant, Nature, 444 (56), 60
  • Chen, D-F, Fetz, E.E. (2005) Characteristic membrane potential trajectories in primate sensorimotor cortex neurons recorded in vivo, Journal of Neurophysiology, 73, 2713-2725
  • Mavoori, J, Jackson, A, Diorio, C, Fetz, E.E (2005) An autonomous implantable computer for neural recording and stimulation in unrestrained primates, Journal of Neuroscience Methods, 148, 71-77
  • Maier, M.A., Shupe, L.E., Fetz, E.E., (2005) Dynamic neural network models of the premotoneuronal circuitry controlling wrist movements in primates, Journal of Computational Neuroscience, 19, 125-146
  • Aumann, T.D., Fetz, E.E. (2004) Oscillatory activity in forelimb muscles of behaving monkeys evoked by microstimulation in the cerebellar nuclei, Neuroscience Letters, 361, 106-110
  • Maier, M.A, Shupe, L.E, Fetz, E.E (2003) Recurrent neural networks of integrate-and-fire cells simulating short-term memory and wrist movement tasks derived from continuous dynamic networks, Journal of Physiology (Paris),, 97, 601-612
  • Seki, K., Perlmutter, S.I.,, Fetz, E.E (2003) Sensory input to primate spinal cord is inhibited presynaptically during voluntary movement, Nature Neuroscience, 6, 1309-1316
  • Fetz, E.E., Shupe, L.E (2003) Recurrent networks: neurophysiological modeling, HANDBOOK OF BRAIN THEORY AND NEURAL NETWORKS, 2nd ed, Cambridge, MA, MIT Press, 960-963 pages, ISBN=0-262-01197-2 (bookchapter)
  • Fetz, E.E., Perlmutter, S.I., Prut, Y. Seki, K. and Votaw, S., Roles of primate spinal interneurons in preparation and execution of voluntary hand movement, Brain Research Reviews, 40, 53-65, 2002
  • Prut, Y., Perlmutter, S.I. and Fetz, E.E., Distributed processing in the motor system: Spinal cord perspective, Progress in Brain Research, 130, 267-278, 2001
  • Fetz, E.E., Chen, D.F., Murthy, V.N., and Matsumura, M., Synaptic interactions mediating synchrony and oscillations in primate sensorimotor cortex, Journal of Physiology (Paris), 94, 323-331, 2000
  • Fetz, E.E., Perlmutter, S.I. and Prut, Y., Functions of mammalian spinal interneurons during movement, Current Opinion in Neurobiology, 10, 699-707, 2000
  • Prut Y, Fetz EE, Primate spinal interneurons show pre-movement instructed delay activity, Nature, 401(6753), 590-4, October 1999 Abstract
  • Fetz EE, Response properties of spinal interneurons in awake, behaving primates., Pain, Suppl 6, S55-60, August 1999 Abstract
  • Aoki, F., Fetz, E. E., Shupe, L., Lettich, E. and Ojemann, G. A., Increased gamma-range activity in human sensorimotor cortex during performance of visuomotor tasks, Clinical Neurophysiology, 110(3), 524-537, 1999
  • Fetz EE, Perlmutter SI, Prut Y, Maier MA, Primate spinal interneurons: muscle fields and response properties during voluntary movement, Progress in Brain Research, 123, 323-30, 1999 Abstract
  • Fetz,E.E., Real-time control of a robotic arm by neuronal ensembles, Nature Neuroscience, 2, 583-584, 1999
  • Perlmutter, S., Maier, M.A., and Fetz, E.E, Activity and output linkages of spinal premotor interneurons during voluntary wrist movements in the monkey, Journal of Neurophysiology, 80, 2475-2494, 1998
  • Maier, M.A., Perlmutter, S.I. and Fetz, E.E., Response patterns and force relations of monkey spinal interneurons during active wrist movement, Journal of Neurophysiology, 80, 2495-2513, 1998
  • Fetz E E, Temporal coding in neural populations?, Science, 278(5345), 1901-2, 12 Dec 1997 Abstract
  • Matsumura M, Chen D, Sawaguchi T, Kubota K, Fetz E E, Synaptic interactions between primate precentral cortex neurons revealed by spike-triggered averaging of intracellular membrane potentials in vivo., Journal of Neuroscience, 16(23), 7757-67, 1 Dec 1996 Abstract
  • Murthy V N, Fetz E E, Synchronization of neurons during local field potential oscillations in sensorimotor cortex of awake monkeys., Journal of Neurophysiology, 76(6), 3968-82, December 1996 Abstract
  • Murthy V N, Fetz E E, Oscillatory activity in sensorimotor cortex of awake monkeys: synchronization of local field potentials and relation to behavior., Journal of Neurophysiology, 76(6), 3949-67, December 1996 Abstract
  • Fetz E E, Perlmutter S I, Maier M A, Flament D, Fortier P A, Response patterns and postspike effects of premotor neurons in cervical spinal cord of behaving monkeys., Canadian Journal of Physiology and Pharmacology, 74(4), 531-46, April 1996 Abstract
  • Fetz E E, Cortical mechanisms controlling limb movement., Current Opinion In Neurobiology, 3(6), 932-9, December 1993 Abstract
  • Reyes A D, Fetz E E, Two modes of interspike interval shortening by brief transient depolarizations in cat neocortical neurons., Journal of Neurophysiology, 69(5), 1661-72, May 1993 Abstract
  • Reyes A D, Fetz E E, Effects of transient depolarizing potentials on the firing rate of cat neocortical neurons., Journal of Neurophysiology, 69(5), 1673-83, May 1993 Abstract
  • Schmied A, Ivarsson C, Fetz E E, Short-term synchronization of motor units in human extensor digitorum communis muscle: relation to contractile properties and voluntary control., Experimental Brain Research, 97(1), 159-72, 1993 Abstract
  • Murthy V N, Fetz E E, Coherent 25- to 35-Hz oscillations in the sensorimotor cortex of awake behaving monkeys., Proceedings of the National Academy of Sciences (USA), 89(12), 5670-4, 15 Jun 1992 Abstract
  • Flament D, Fortier P A, Fetz E E, Response patterns and postspike effects of peripheral afferents in dorsal root ganglia of behaving monkeys., Journal of Neurophysiology, 67(4), 875-89, April 1992 Abstract
  • Kenyon G T, Puff R D, Fetz E E, A general diffusion model for analyzing the efficacy of synaptic input to threshold neurons., Biological Cybernetics, 67(2), 133-41, 1992 Abstract
  • Fetz, E.E., Are movement parameters recognizably coded in activity of single neurons?, Behavioral and Brain Sciences, 15, 679-690, 1992
  • Cheney P D, Fetz E E, Mewes K, Neural mechanisms underlying corticospinal and rubrospinal control of limb movements., Progress In Brain Research, 87, 213-52, 1991 Abstract
  • Fetz Eberhard E, Shupe Larry E, Murthy Venkatesh N, Neural networks controlling wrist movements, 675-679, 17 Jun 1990
  • Fetz E E, Cheney P D, Mewes K, Palmer S, Control of forelimb muscle activity by populations of corticomotoneuronal and rubromotoneuronal cells., Progress In Brain Research, 80, 437-49; discussion 4, 1989 Abstract
  • Cheney PD, Mewes K, Fetz EE, Encoding of motor parameters by corticomotoneuronal (CM) and rubromotoneuronal (RM) cells producing postspike facilitation of forelimb muscles in the behaving monkey, Behavioural Brain Research, 28(1-2), 181-91, 1988 Abstract
  • Komatsu Y, Nakajima S, Toyama K, Fetz EE, Intracortical connectivity revealed by spike-triggered averaging in slice preparations of cat visual cortex, Brain Research, 442(2), 359-62, March 1988 Abstract
  • Matsumura M, Cope T, Fetz EE, Sustained excitatory synaptic input to motor cortex neurons in awake animals revealed by intracellular recording of membrane potentials, Experimental Brain Research, 70(3), 463-9, 1988 Abstract
  • Schmied A, Fetz EE, Activity-related changes in electrical thresholds of pyramidal tract axons in the behaving monkey, Experimental Brain Research, 65(2), 352-60, 1987 Abstract
  • Fetz EE, Cheney PD, Palmer SS, Activity of forelimb motor units and corticomotoneuronal cells during ramp-and-hold torque responses: comparisons with oculomotor cells, Progress in Brain Research, 64, 133-41, 1986 Abstract

Profile Details

Last Updated: 1/30/2010

COS Expertise ID #307471
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