University at Buffalo School of Public Health and Health Professions Social and Preventive Medicine Interim ChairAppointed: 1998 University at Buffalo School of Public Health and Health Professions Social and Preventive Medicine ProfessorAppointed: 1998 University at Buffalo Roswell Park Cancer Institute Social and Preventive Medicine Professor (Hs)Appointed: 1996 Research Institute on Addictions Social and Preventive Medicine Professor (Hs)Appointed: 1995 University at Buffalo School of Public Health and Health Professions Social and Preventive Medicine Nutrition Program Professor (Hs)Appointed: 1988 | |
QualificationsM.S., University of Wisconsin - Madison, Preventive Medicine (Epidemiology), 1986. Ph.D., University of Wisconsin-Madison, Nutritional Sciences, Statistics, 1986. M.S., University of Wisconsin - Madison, Nutritional Sciences, 1984. B.S., University of Michigan-Ann Arbor, Human Nutrition, 1975. Expertise and Research InterestsMy research focuses on the epidemiology of diet in relation to cancer risk with a particular focus on breast cancer. We have been examining the association of polymorphisms in genes as modifiers of the effect of other exposures such as diet, alcohol andsmoking in cancer risk. Recent work has focused on differences in the association between alcohol and breast cancer risk depending on which of the alcohol dehydrogenase 3 gene variants are carried. This research has led to a focus on folate and alcohol and other factors related to one-carbon metabolism in relation to breast cancer risk. New work includes examination of p53 mutational spectra in breast tumors as an outcome. Further, we are examining residential history as an indicator of environmental exposures to elucidate a possible role of those exposures in breast cancer epidemiology. KeywordsCOS Keywords:Breast Cancer, Cancer Or Carcinogenesis, Cardiovascular Diseases, Epidemiology, Lung Cancer, Nutrition Or Dietetics, Prostate Cancer.Additional Terms:Breast Cancer, Cancer Epidemiology, Carotenoids, Diet, Epidemiology, Folate, Lung Cancer, Nutrition, Nutritional Epidemiology, Prostate Cancer.Languages(Reading, Writing, Speaking)French: (Basic, Basic, Basic) MembershipsAmerican Association for Cancer Research American Association for the Advancement of Science American College of Epidemiology American Dietetic Association American Epidemiological Society American Society for Nutritional Sciences Erie County Nutrition Committee Federation of American Societies for Experimental Biology Society for Epidemiologic Research Women in Cancer Research Previous Positions1988-1993, Assistant Professor,
University at Buffalo,
School of Medicine and Biomedical Sciences,
Social and Preventive Medicine
1987-1988, Postdoctoral Fellow,
University at Buffalo,
School of Medicine and Biomedical Sciences,
Social and Preventive Medicine
Funding Received- Department of the Army:
Lifetime Alcohol Exposure and Breast Cancer Risk,
$1,650,000,
Sep 14, 1996
to Sep 13, 2001.
- National Institutes of Health (NIH):
Methylation and Oxidation in Breast Cancer Epidemiology,
$2,394,000,
Jul 1, 2002
to Jun 30, 2006.
- USAMRDC:
The Molecular Epidemiology of Breast Cancer,
$101,580,
9/94
to 8/97.
- National Institutes of Health (NIH):
Environmental & Genetic Determinants of Breast Cancer,
$114,007,
9/93
to 9/96.
- National Institutes of Health (NIH):
RCDA: Nutritional Epidemiology of Cancer,
$66,000,
8/92
to 7/97.
- NCI:
Medical Sociology, Epidemiology and Control of Cancer,
$134,930,
6/1/91
to 5/31/97.
- National Institutes of Health (NIH):
Women's Health Initiative,
$10,910,019,
3/93
to 3/2005.
- United States Department of Defense (DOD):
Breast Center of Excellence: Molecular epidemiolgy and mechanisms for breast carcinogenesis, alcohol drinking as a paradigm,
2003
to 2008.
- Department of the Army:
Environmental Exposures at Birth and at Menarche and Risk of Breast Cancer,
$300,000,
2000
to 2002.
- National Institutes of Health (NIH):
Breast Cancer Risk: Residential Environment and Genetics,
$150,000,
2000
to 2002.
- NIAAA:
Alcohol Consumption and Lung Cancer,
$333,295,
12/93
to 11/98.
Publications- Freudenheim JL, Ambrosone CB, Moysich KB, Vena JE, Graham S, Marshall JR, Muti P, Laughlin R, Nemoto T, Harty LC, Crits GA, Chan AWK, Shields P, Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer, Cancer Causes and Control, 10, 369-77, 1999
- Freudenheim JL, Marshall JR, Graham S, et al., Vegetables, fruits and related nutrients in relation to risk of premenopausal breast cancer, Journal of the National Cancer Institute, 88, 340-348, 1996
- Freudenheim JL, Marshall JR, Graham S, et al., Exposure to breastmilk in infancy and the risk of breast cancer, Epidemiology, 5, 324-31, 1994
- Freudenheim JL, A review of study designs and methods of dietary assessment in nutritional epidemiology of chronic disease, Journal of Nutrition, 123, 401-5, 1993
- Freudenheim JL, Marshall JR, The problem of profound mismeasurement and the power of epidemiologic studies of diet and cancer, Nutrition and Cancer, 11(988), 243-50
- Freudenheim, JL et al, Lung cancer in humans is not associated with lifetime alcohol consumption or with genetic variation in alcohol dehydrogenase 3 (ADH3), Journal of Nutrition, in press
Profile DetailsIndividual Expertise profile of Jo L. Freudenheim, Copyright Jo L. Freudenheim. © COS Expertise TM, 2010, ProQuest LLC All rights reserved. |