Dr. Venugopal Gangur

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Michigan State University
College of Agriculture and Nat. Res/College of Veterinary Medicine
Food Allergy and Immunology
Associate ProfessorAppointed: 2001
Professional Headshot of Venugopal Gangur

Mailing Address

#302-B GM Trout Bldg.
East Lansing, Michigan 48823
United States

Contact Information

Phone: (517) 355-8474, ext. 134
Fax: (517) 353-8963
gangur@msu.edu

Qualifications

Ph.D., University of Manitoba, Allergy and Immunology, 1996.
M.V.S., Indian Veterinary Research Institute, Immunology, 1990.
D.V.M., Bangalore Veterinary College, Veterinary Medicine, 1988.

Expertise and Research Interests

Food allergy and immunology
Breast milk vs. atopy
Infant immune system vs. atopy
Animal models for food allergy
Risk assessment of food for allergenicity
Detection methods for food allergens
Adverse reactions to food and food associated agents
Allergy, asthma, and immunology
Cytokines, chemokines, and inflammation
Immune responses to food-derived antigens

Other Expertise

Molecular genetics of immune response
Animal breeding

Future Research

Dissection of molecular basis of hypersensitivity to common food allergens
Hazard assessment of novel food (eg. GM foods) for potential allergenicity
Interaction between environment and the host in food related hypersensitivity and asthma

Industrial Relevance

- Identification of risk vs. protective factors in breast milk should lead to development of improved infant food formulae for the prevention and management of allergies in childhood
- Availability of novel methods for predicting allergenic potential of foods should lead to introduction of safer foods (e.g., GMO) into the food chain

Keywords

COS Keywords:

Allergy, Animal Genetics or Breeding, Animal Models, Asthma, Breast Milk, Cytokines, Food Engineering, Food Safety, Food Sciences, Immunology, Infants, Inflammation, Nutrition or Dietetics, Toxicology, Veterinary Medicine.

Additional Terms:

Allergen, Breast Milk, Chemokine, Cytokine, Food, Food Allergy, GM Food, Immune Response, Immunology, Infant, Inflammation.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
Kannada: (Fluent, Fluent, Fluent)
Hindi: (Functional, Functional, Basic)

Memberships

American Association for the Advancement of Science
American Association of Immunologists

Honors and Awards

2007, AAI Jr Faculty Travel Award, American Association of Immunolgists
2006, AAI Jr. Faculty Award, American Association of Immunologists
1998, Respiratory 2000 International Young Investigator Award, Scherring-Plough Pharmaceuticals, NJ, USA, Allergy & Immunology
1998-2000, Fogarty International Fellowship Award, Fogarty International Center, DHHS, National Institutes of Health, Immunology
1998, Travel Grant Award, Manitoba Health Research Council, Canada, Allergy & Immunology
1997-1998, Tom Olenick Research Award in Immunology & Allergy, Health Sciences Centre Foundation, Winnipeg, Canada, University of Manitoba, Allergy & Immunology
1997-1998, Postdoctoral Fellowship Award, Manitoba Health Research Council, Canada, Allergy & Immunology
1995-1996, Doctoral Studentship Award, Manitoba Health Research Council, Canada, Allergy & Immunology
1995, Travel Grant Award, University of Manitoba, Allergy & Immunology
1994, Travel Grant Award, American Academy of Allergy, Asthma & Immunology, U.S.A., Allergy & Immunology
1994-1995, Doctoral Studentship Award, Manitoba Health Research Council, Canada, Allergy & Immunology
1994, Graduate Student Fellowship Award, University of Manitoba, Allergy & Immunology

Previous Positions

2001-2006, Assistant Professor, Michigan State University, College of Veterinary Medicine, Food Allergy and Immunology Laboratory
2001-2006, Assistant Professor, Michigan State University, College of Agriculture & Natural Resources, Food Science and Human Nutrition
1998-2000, Visiting Fellow, National Institute of Health (NIH)
1996-1998, Postdoctoral Fellow, University of Manitoba, Faculty of Medicine, Immunology
1992-1996, Research Assistant, University of Manitoba, Faculty of Medicine, Immunology

Funding Received

  • American Association of Immunologists: Travel Award, $500., 2007 to .
  • Environmental Protection Agency (EPA): Safety assessment of dietary proteins for allergenicity using an adjuvant free mouse model, $447,774, 2006 to 2009.
  • American Association of Immunologists: Junior Faculty Travel Award, $500, 2006 to .
  • Environmental Protection Agency (EPA): Biomarkers for asthma, atopy and halogenated organic compounds, $749,939, 2003 to 2006.
  • Gerber Companies Foundation: Protective Immune Constituents and Pathogenic Toxicants in Breast Milk and The Risk of Allergy; Atopic Eczema; and Asthm, $138,198, 2003 to 2005.
  • IRGP, Michigan State University Foundation: Development of a food allergy model using gene knockout mice, $50,000, 2002 to 2004.
  • Manitoba Health Research Council, Winnipeg, Canada: Salary Support, $26,320, 1998 to 1999.
  • Health Sciences Center Foundation of Winnipeg, Canada: Tom-Olenic Research Award in Immunology, $6,000, 1997 to 1998.
  • Manitoba Health Research Council, Winnipeg, Canada: Salary Support, $24,775, 1997 to 1998.
  • Manitoba Health Research Council, Winnipeg, Canada: Salary Support, $14,265, 1995 to 1996.
  • Manitoba Health Research Council, Winnipeg, Canada: Salary Support, $14,265, 1994 to 1995.
  • The University of Manitoba, Canada: Salary Support, $10,000, 1994 to 1995.
  • Manitoba Health Research Council, Winnipeg, Canada: Travel Grant, $1,000, to 1998.
  • American Academy of Allergy, Asthma & Immunology, USA: Travel Grant, $750, to 1994.

Publications

  • Birmingham NP, Parvataneni S, Hassan HM, Harkema J, Samineni S, Navuluri L, Kelly CJ, Gangur V. (2008) An adjuvant-free mouse model of tree nut allergy using hazelnut as a model tree nut., Int Arch Allergy Immunol, 144 (3), 203-10
  • Brooks K, Hasan H, Samineni S, Gangur V, Karmaus W. (2008) Placental p,p'-dichlorodiphenyldichloroethylene and cord blood immune markers., Pediatr Allergy Immunol., 18 (7), 621-4.
  • Birmingham et al, Hazelnut Allergy: Evidence That Hazelnut Can Directly Elicit Specific IgE Antibody Response Via Activating Type 2 Cytokines in Mice, Int Arch Allergy Immunol., 295-302, Jun 2005
  • Gangur V, Food Allergy: a Synopsis, Hand Book of Food Science, In Press, 2005
  • Karmaus W and V. Gangur, Does Allo-immune Reactivity Play a Role in the Prenatal Programming of Childhood Allergy?, Clin Exp Allergy, 35(4), 405-7, 2005
  • Gangur et al, Sesame Allergy: a Growing Food Allergy of Global Proportions?, Annals of Allergy Asthma & Immunology, In Press, 2005
  • Campbell JD, Gangur V, Simons FE, HayGlass KT, Allergic humans are hyporesponsive to a CXCR3 ligand-mediated Th1 immunity-promoting loop, FASEB J, 18(2), 329-331, February 2004
  • Birmingham N, Payankaulam S, Thanesvorakul S, Stefura B, HayGlass K, Gangur V, An ELISA-based method for measurement of food-specific IgE antibody in mouse serum: An alternative to the passive cutaneous anaphylaxis assay, Journal of Immunological Methods, 275(1-2), 89-98, April 2003
  • Gangur V, Birmingham NP, Thanesvorakul S, Joseph S, CCR3 and CXCR3 as drug targets for allergy: Principles and potential, Curr Drug Targets Inflamm Allergy, 2(1), 53-62, March 2003
  • Birmingham NP, Thanesvorakul S and V. Gangur, Relative immunogenicity of common vs. rare/non-allergenic foods, Journal of Food Protection, 65(12), 1988-91, December 2002
  • Gangur V, Birmingham NP, Thanesvorakul S, Chemokines in health and disease, Veterinary Immunology and Immunopathology, 86(3-4), 127-36, July 2002 Abstract
  • Neil P Birmingham, Sirinart Thanesvorakul and Venu Gangur, Food allergy: Relative antigenicity of common vs. rarely allergenic foods, FASEB Journal, 16(5), A1240 AB#931.11, 2002
  • HayGlass KT, Gangur V, Campbell JD, Simons FE, Experimental approaches to analysis of immune dysregulation in human allergic disease, Immunopharmacology, 48(3), 283-90, 2000 Abstract
  • Gangur V, Oppenheim JJ, Are chemokines essential or secondary participants in allergic responses?, Annals of Allergy, Asthma, and Immunology, 84(6), 569-79, June 2000 Abstract
  • HagGlass KT, Venugopal Gangur and FER Simons, Chemokines--An immunoregulatory role in allergy beyond chemotaxis, Allergy and Clinical Immunology International, 12(1), 13-19, 2000
  • Gangur V, Simons FE, HayGlass KT, IP-10 mediated reinforcement of human type 1 cytokine synthesis to environmental allergens among non-atopic subjects, International Archives of Allergy and Immunology, 118(2-4), 387-90, 1999 Abstract
  • Gangur V, Simons FE, Hayglass KT, Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-gamma over IL-4 responses, FASEB Journal, 12(9), 705-13, June 1998 Abstract
  • Venugopal Gangur, FER Simons, and KT HayGlass, Human IP-10 selectively promotes dominance of polyclonally activated and evironmental antigen-driven IFN-g over IL-4 responses, FASEB Journal, 12(4), A264, 1538, 1998
  • Trivedi HN, HayGlass KT, Gangur V, Allardice JG, Embree JE, Plummer FA, Analysis of neonatal T cell and antigen presenting cell functions, Human Immunology, 57(2), 69-79, October 1997 Abstract
  • Venugopal G, Yang M, Luo Z, Salo D, Cheang M, Mohapatra SS, Analysis of Tcrvb8, Il4, and Ifg as genetic predisposition factors for atopic IgE response in a murine model, Journal of Immunology, 155(11), 5463-70, 1995 Abstract
  • Gangur Venugopal, Z Luo and SS Mohapatra, Inheritance of IgE immune responsiveness in mouse, Journal of Allergy and Clinical Immunology, 178, 151, 1995
  • Venugopal G, Trivedi HN, Mohapatra SS, Arbitrary single short primers identify polymorphic DNA markers that distinguish inbred strains of mice, Biochemical and Biophysical Research Communications, 203(1), 659-65, 1994 Abstract
  • Gangur Venugopal and SS Mohapatra, Identification of genetic markers for IgE responsiveness in murine system, Journal of Allergy and Clinical Immunology, 93, 252, 1994
  • Venugopal G, Mohapatra S, Salo D, Mohapatra S, Multiple mismatch annealing: Basis for random amplified polymorphic DNA fingerprinting, Biochemical and Biophysical Research Communications, 197(3), 1382-7, 1993
  • Venugopal G, Ram GC, Bansal MP, Determination of optimal in vitro conditions for caprine alternative complement pathway assay, Veterinary Immunology and Immunopathology, 32(3-4), 359-64, May 1992 Abstract

Profile Details

Last Verified: 9/3/2008

COS Expertise ID #312925
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