George Kenneth Haines

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Yale University
School of Medicine
Pathology
Associate Professor
Professional Headshot of George Kenneth Haines

Mailing Address

Surgical Pathology
200 South Frontage Rd
EP2-608
New Haven, Connecticut 06510
United States

Contact Information

Phone: (203) 785-3937
k.haines@yale.edu

Qualifications

Residency, Northwestern University, Anatomic and Clinical Pathology, 1992.
M.D., Ohio State University, 1987.

Expertise and Research Interests

Diagnostic Surgical Pathology:
- Head & Neck Pathology
- Breast and Gynecologic Pathology
- Gastrointestinal Pathology

Research Interests:
- Nitrosative stress and carcinogenesis
- Rheumatoid arthritis

Keywords

COS Keywords:

Arthritis, Cancer Or Carcinogenesis, Pathology, Stress, Surgery.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
French: (Basic, Basic, Basic)

Memberships

American Society of Clinical Pathology

Honors and Awards

2006-2007, Averill A. Liebow Award, Department of Pathology, Yale University

Previous Positions

1998-2006, Associate Professor, Northwestern University, Feinberg School of Medicine, Pathology
1992-1998, Assistant Professor, Northwestern University, Feinberg School of Medicine, Pathology

Publications

  • Shahrara S, Proudfoot AE, Park CC, Volin MV, Haines GK, Woods JM, Aikens CH, Handel TM, Pope RM (Mar 2008) Inhibition of monocyte chemoattractant protein-1 ameliorates rat adjuvant-induced arthritis., Journal of immunology (Baltimore, Md. : 1950), 180 (5), 3447-56 Abstract
  • Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK, Wu T, Li QZ, Davis LS, Mohan C, Perlman H (Feb 2008) Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity., Immunity, 28 (2), 206-17 Abstract
  • Bentz BG, Hammer ND, Milash B, Klein S, Burnett DM, Radosevich JA, Haines Iii GK (Feb 2008) The Kinetics and Redox State of Nitric Oxide Determine the Biological Consequences in Lung Adenocarcinoma., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 28 (6), 301-311 Abstract
  • Volin MV, Shahrara S, Haines GK, Woods JM, Koch AE (Jan 2008) Expression of mucin 3 and mucin 5AC in arthritic synovial tissue., Arthritis and rheumatism, 58 (1), 46-52 Abstract
  • Haines GK, Wiley E, Susnik B, Apple SK, Frkovic-Grazio S, Reyes C, Goldstein LC, Dadmanesh F, Gown AM, Nadji M, Bracko M, Tavassoli FA (Jan 2008) HER2 in well differentiated breast cancer: is testing necessary? Abstract
  • Vesper BJ, Altman KW, Elseth KM, Haines GK, Pavlova SI, Tao L, Tarjan G, Radosevich JA (Dec 2007) Gastroesophageal Reflux Disease (GERD): Is There More to the Story? Abstract
  • Olivier V, Haines GK, Tan Y, Satchell KJ (Oct 2007) Hemolysin and the multifunctional autoprocessing RTX toxin are virulence factors during intestinal infection of mice with Vibrio cholerae El Tor O1 strains., Infection and immunity, 75 (10), 5035-42 Abstract
  • Ruth JH, Rottman JB, Kingsbury GA, Coyle AJ, Haines GK, Pope RM, Koch AE (May 2007) ICOS and B7 costimulatory molecule expression identifies activated cellular subsets in rheumatoid arthritis., Cytometry. Part A : the journal of the International Society for Analytical Cytology, 71 (5), 317-26 Abstract
  • Rhee TK, Young JY, Larson AC, Haines GK, Sato KT, Salem R, Mulcahy MF, Kulik LM, Paunesku T, Woloschak GE, Omary RA (May 2007) Effect of transcatheter arterial embolization on levels of hypoxia-inducible factor-1alpha in rabbit VX2 liver tumors., Journal of vascular and interventional radiology : JVIR, 18 (5), 639-45 Abstract
  • Altman KW, Waltonen JD, Tarjan G, Radosevich JA, Haines GK (Mar 2007) Human lung mucous glands manifest evidence of the H+/K+-ATPase proton pump., The Annals of otology, rhinology, and laryngology, 116 (3), 229-34 Abstract
  • Scatizzi JC, Hutcheson J, Bickel E, Haines GK, Perlman H (2007) Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis., Arthritis research & therapy, 9 (3), R49 Abstract
  • Shahrara S, Castro-Rueda HP, Haines GK, Koch AE (2007) Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues., Arthritis research & therapy, 9 (5), R112 Abstract
  • Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H (Oct 2006) Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis., Arthritis and rheumatism, 54 (10), 3182-93 Abstract
  • Haas CS, Amin MA, Allen BB, Ruth JH, Haines GK, Woods JM, Koch AE (Aug 2006) Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis., Arthritis and rheumatism, 54 (8), 2402-14 Abstract
  • Haas CS, Creighton CJ, Pi X, Maine I, Koch AE, Haines GK, Ling S, Chinnaiyan AM, Holoshitz J (Jul 2006) Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins., Arthritis and rheumatism, 54 (7), 2047-60 Abstract
  • Scatizzi JC, Hutcheson J, Bickel E, Woods JM, Klosowska K, Moore TL, Haines GK, Perlman H (May 2006) p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis., The American journal of pathology, 168 (5), 1531-41 Abstract
  • Ruth JH, Haas CS, Park CC, Amin MA, Martinez RJ, Haines GK, Shahrara S, Campbell PL, Koch AE (Mar 2006) CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathway., Arthritis and rheumatism, 54 (3), 765-78 Abstract
  • Reid RR, Said HK, Yu M, Haines GK, Few JW (Jan 2006) Revisiting upper eyelid anatomy: introduction of the septal extension., Plastic and reconstructive surgery, 117 (1), 65-6; discussion 71- Abstract
  • Pakozdi A, Amin MA, Haas CS, Martinez RJ, Haines GK, Santos LL, Morand EF, David JR, Koch AE (2006) Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis., Arthritis research & therapy, 8 (4), R132 Abstract
  • Haas CS, Martinez RJ, Attia N, Haines GK, Campbell PL, Koch AE (Dec 2005) Chemokine receptor expression in rat adjuvant-induced arthritis., Arthritis and rheumatism, 52 (12), 3718-30 Abstract
  • Liu H, Eksarko P, Temkin V, Haines GK, Perlman H, Koch AE, Thimmapaya B, Pope RM (Dec 2005) Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis., Journal of immunology (Baltimore, Md. : 1950), 175 (12), 8337-45 Abstract
  • Altman KW, Waltonen JD, Hammer ND, Radosevich JA, Haines GK (Nov 2005) Proton pump (H+/K+-ATPase) expression in human laryngeal seromucinous glands., Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 133 (5), 718-24 Abstract
  • Haines GK, Sayed BA, Rohrer MS, Olivier V, Satchell KJ (Sep 2005) Role of toll-like receptor 4 in the proinflammatory response to Vibrio cholerae O1 El tor strains deficient in production of cholera toxin and accessory toxins., Infection and immunity, 73 (9), 6157-64 Abstract
  • Seiberling KA, Conley DB, Tripathi A, Grammer LC, Shuh L, Haines GK, Schleimer R, Kern RC (Sep 2005) Superantigens and chronic rhinosinusitis: detection of staphylococcal exotoxins in nasal polyps., The Laryngoscope, 115 (9), 1580-5 Abstract
  • Lynn-Macrae A, Haines GK, Altman KW (Sep 2005) Primary chordoma of the lateral nasal wall: case report and review., Ear, nose, & throat journal, 84 (9), 593-5 Abstract
  • Shahrara S, Proudfoot AE, Woods JM, Ruth JH, Amin MA, Park CC, Haas CS, Pope RM, Haines GK, Zha YY, Koch AE (Jun 2005) Amelioration of rat adjuvant-induced arthritis by Met-RANTES., Arthritis and rheumatism, 52 (6), 1907-19 Abstract
  • Kern RC, Conley DB, Haines GK, Robinson AM (Dec 2004) Treatment of olfactory dysfunction, II: studies with minocycline., The Laryngoscope, 114 (12), 2200-4 Abstract
  • Brown NJ, Hutcheson J, Bickel E, Scatizzi JC, Albee LD, Haines GK, Eslick J, Bradley K, Taricone E, Perlman H (Dec 2004) Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo., Journal of immunology (Baltimore, Md. : 1950), 173 (12), 7584-93 Abstract
  • Bentz BG, Hammer ND, Radosevich JA, Haines GK (Dec 2004) Nitrosative stress induces DNA strand breaks but not caspase mediated apoptosis in a lung cancer cell line., Journal of carcinogenesis, 3 (1), 16 Abstract
  • Kern RC, Conley DB, Haines GK, Robinson AM (Feb 2004) Pathology of the olfactory mucosa: implications for the treatment of olfactory dysfunction., The Laryngoscope, 114 (2), 279-85 Abstract
  • Batra PS, Kern RC, Tripathi A, Conley DB, Ditto AM, Haines GK, Yarnold PR, Grammar L (Oct 2003) Outcome analysis of endoscopic sinus surgery in patients with nasal polyps and asthma., The Laryngoscope, 113 (10), 1703-6 Abstract
  • Perlman H, Bradley K, Liu H, Cole S, Shamiyeh E, Smith RC, Walsh K, Fiore S, Koch AE, Firestein GS, Haines GK, Pope RM (Jan 2003) IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts., Journal of immunology (Baltimore, Md. : 1950), 170 (2), 838-45 Abstract
  • Gong Y, Sun X, Haines GK, Pins MR (Jan 2003) Renal cell carcinoma, chromophobe type, with collecting duct carcinoma and sarcomatoid components., Archives of pathology & laboratory medicine, 127 (1), e38-40 Abstract
  • Aquino BF, Chandra RK, Haines GK, Micco AG (Nov 2002) Neuroendocrine adenoma of the middle ear., Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 127 (5), 477-9 Abstract
  • Sidle DM, Haines GK, Altman KW (Nov 2002) Bilateral vocal process papillomas: report of a case., Ear, nose, & throat journal, 81 (11), 790-1 Abstract
  • Hu X, Herrero C, Li WP, Antoniv TT, Falck-Pedersen E, Koch AE, Woods JM, Haines GK, Ivashkiv LB (Sep 2002) Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation., Nature immunology, 3 (9), 859-66 Abstract
  • Moran JV, Conley DB, Grammer LC, Haines GK, Kern RC, Yarnold PR, Tripathi A, Harris KE, Ditto AM, Specific inflammatory cell types and disease severity as predictors of postsurgical outcomes in patients with chronic sinusitis., Allergy and asthma proceedings : the official journal of regional and state allergy societies, 24 (6), 431-6 Abstract
  • Chandra RK, Conley DB, Haines GK, Kern RC, Long-term effects of FloSeal packing after endoscopic sinus surgery., American journal of rhinology, 19 (3), 240-3 Abstract

Profile Details

Last Updated: 4/9/2008

COS Expertise ID #1293182
Reference this profile directly: http://myprofile.cos.com/gkh3