Jay I. Goodman

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Michigan State University

Mailing Address

B423B Life Science
Michigan State University
East Lansing, Michigan 48824
United States

Contact Information

Phone: (517) 353-9346
goodman3@msu.edu

Expertise and Research Interests

Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

Keywords

COS Keywords:

Chemical Carcinogenesis, Environment (Health Or Safety Or Medical), Environmental Health, Environmental Medicine, Environmental Toxicology, Gene Expression, Image Processing, Molecular Oncology, Nucleic Acid Hybridization, Polymerase Chain Reaction.

Additional Terms:

Chemical Carcinogenesis, Dna Methylation, Environmental Toxicology, Enzyme Activity, Gel Electrophoresis, Gene Expression, Gene Mutation, Genetic Regulatory Element, High Performance Liquid Chromatography, Image Processing, Laboratory Mouse, Liver Neoplasm, Molecular Oncology, Northern Blotting, Nucleic Acid Hybridization, Nucleic Acid Sequence, Polymerase Chain Reaction, Protooncogene, Regulatory Gene, S Adenosylmethionine, Scintillation Counter, Southern Blotting, Toxicant Interaction, Tumor Promoter, Western Blotting.

Funding Received

  • National Institutes of Health (NIH), 2 R01 ES05299-04A2, THRESHOLD MECHANISMS IN ENVIRONMENTAL TOXICOLOGY, $151967, 1996-1998

Publications

  • Goodman JI, The traditional toxicologic paradigm is correct: dose influences mechanism., Environmental Health Perspectives, 106 Suppl 1, 285-8, 1998 Abstract
  • Counts JL, Goodman JI, Hypomethylation of DNA: a nongenotoxic mechanism involved in tumor promotion., Toxicology Letters, 82-83, 663-72, December 1995 Abstract
  • Counts JL, Goodman JI, Alterations in DNA methylation may play a variety of roles in carcinogenesis., Cell, 83(1), 13-5, 6 Oct 1995 Abstract
  • Counts JL, Goodman JI, Principles underlying dose selection for, and extrapolation from, the carcinogen bioassay: dose influences mechanism., Regul Toxicol Pharmacol, 21(3), 418-21, 1995 Abstract
  • Goodman JI, An analysis of the National Toxicology Program''s \(NTP\) Technical Report \(NTP TR 421\) on the toxicology and carcinogenesis studies of talc., Regul Toxicol Pharmacol, 21(2), 244-9, 1995 Abstract
  • Counts JL, Goodman JI, Hypomethylation of DNA: a possible epigenetic mechanism involved in tumor promotion., Prog Clin Biol Res, 391, 81-101, 1995 Abstract
  • Trosko JE, Goodman JI, Intercellular communication may facilitate apoptosis: implications for tumor promotion., Molecular Carcinogenesis, 11(1), 8-12, 1994 Abstract
  • Goodman JI, A rational approach to risk assessment requires the use of biological information: an analysis of the National Toxicology Program \(NTP\), final report of the advisory review by the NTP Board of Scien, Regul Toxicol Pharmacol, 19(1), 51-9, 1994 Abstract

Profile Details

Last Updated: 6/19/1997

COS Expertise ID #535522
Reference this profile directly: http://myprofile.cos.com/goodmanj22