Dr. David S. Jardine

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University of Washington
School of Medicine
Anesthesiology
Associate Professor
University of Washington
School of Medicine
Pediatrics
Pediatric Critical Care
Associate ProfessorAppointed: 2000
University of Washington
School of Medicine
Anesthesiology
Pediatric Anesthesiology
Associate ProfessorAppointed: 1996

Mailing Address

Box 356540
Health Sciences Center
1959 NE Pacific St
University of Washington
Seattle, Washington 98195
United States

Contact Information

Phone: (206) 616-4858
Fax: (206) 685-3079
dsj@u.washington.edu

Qualifications

M.D., Johns Hopkins University, Medicine, 1980.
B.A., University of Oklahoma, Letters, 1976.

Expertise and Research Interests

The role of heat shock proteins in the prevention of apoptosis in neural cells
Heat shock proteins as marker of hyperthermic injury
Hemorrhagic shock and encephalopathy syndrome
Hyperthermic injury during infancy
Investigation of abnormal MRI signal caused by hyperoxia under general anesthesia
Radiographic changes in patients receiving high frequency oscillating ventilation

Keywords

COS Keywords:

Anesthesiology, Apoptosis, Hyperthermia, Oscillations, Pediatrics.

Additional Terms:

Pediatric Anesthesiology, Pediatric Critical Care.

Memberships

American Academy of Pediatrics
American Society of Anesthesiologists
Association of University Anesthesiologists
Society of Critical Care Medicine

Previous Positions

1997-1998, Senior Visiting Fellow, University of Warwick, Faculty of Science, Biological Sciences, Molecular Medicine
1990-1996, Assistant Professor, University of Washington, School of Medicine, Anesthesiology, Pediatric Anesthesiology
1987-1990, Acting Assistant Professor, University of Washington, School of Medicine, Anesthesiology, Pediatric Anesthesiology
1986-1987, Fellow, University of Pennsylvania, School of Medicine, Anesthesiology, Pediatric Anesthesiology and Critical Care
1984-1986, Resident, University of Pennsylvania, School of Medicine, Anesthesiology
1983-1984, Chief Resident, University of Pittsburgh, School of Medicine, Pediatrics
1980-1983, Resident, Children's Hospital of Pittsburgh, School of Medicine, Pediatrics

Funding Received

  • National Institutes of Health (NIH): The role of heat shock proteins in the prevention of neuronal apoptosis, $443,200, Oct 1999 to Sep 2004.
  • SIDS Foundation of Washington: Heat shock protein gene expression as a possible marker for SIDS, $20,000, Jan 1, 2001 to Jul 30, 2002.
  • Center for Ecogenetics, University of Washington: Heat shock proteins as biomarkers for hemorrhagic shock and encephalopathy syndrome, $25,000, Apr 4, 2002 to Mar 30, 2003.
  • National Institutes of Health (NIH): National Collaborative Pediatric Critical Care Research Network, $19760 annually, 2007 to 2010.
  • National Institutes of Health (NIH): Biomarkers of hyperthermia in sudden infant death, $197,000, 2006 to 2008.
  • Alliance Pharmaceutical Corp.: Phase II testing of partial liquid ventilation with AFO141 (sterile Perflubron) in children with acute parenchymal lung injury, $52,000, 1995 to 1996.
  • Biomedical Research Program: An animal model of life threatening hyperthermia during infancy, $5,000, 1989 to 1990.

Publications

  • Jardine, DS (2007) Heat illness and heat stroke, Pediatrics in Review, 28 (7), 249-58
  • Anderson MR, Jewett EA, Cull WL, Jardine DS, Outwater KM, Mulvey HJ, Practice of pediatric critical care medicine: results of the Future of Pediatric Education II survey of sections project, Pediatr Crit Care Med, 4(4), 412-7, 2003
  • Frigon C, Jardine DS, Weinberger E, Heckbert SR, Shaw DW, Fraction of inspired oxygen in relation to cerebrospinal fluid hyperintensity on FLAIR MR imaging of the brain in children and young adults undergoing anesthesia, American Journal of Roentgenology, 179(3), 791-6, September 2002
  • Brogan TV, Bratton SL, Meyer RJ, O'Rourke PP, Jardine DS, Nonpulmonary organ failure and outcome in children treated with high-frequency oscillatory ventilation, Journal of Critical Care, 15(1), 5-11, March 2000 Abstract
  • Brogan TV, Mellema JD, Jardine DS, Severe dactinomycin overdose in an 18-month-old child, Medical and Pediatric Oncology, 33(5), 506-7, November 1999 Abstract
  • Jardine DS, Winters WD, Shaw DW, CT scan abnormalities in a series of patients with hemorrhagic shock and encephalopathy syndrome, Pediatric Radiology, 27(6), 540-4, June 1997 Abstract
  • Bratton S L, Jardine D S, Mirkes P E, Constitutive synthesis of heat shock protein (72 kD) in human peripheral blood mononuclear cells: implications for use as a clinical test of recent thermal stress., International Journal of Hyperthermia, 13(2), 157-68, Spring 1997 Abstract
  • Jardine D S, Bratton S L, Using characteristic changes in laboratory values to assist in the diagnosis of hemorrhagic shock and encephalopathy syndrome., Pediatrics, 96(6), 1126-31, December 1995 Abstract
  • Levy F H, Bratton S L, Jardine D S, Routine chest radiographs following repositioning of endotracheal tubes are necessary to assess correct position in pediatric patients., Chest, 106(5), 1508-10, November 1994 Abstract
  • Bratton S L, Jardine D S, Morray J P, Serial neurologic examinations after near drowning and outcome., Archives of Pediatrics and Adolescent Medicine, 148(2), 167-70, February 1994 Abstract
  • 12. Davis, M., Osaki, C., Gordon, D., Hinds, M.W., Mottram, K., Winegar, C., Avner, E.D., Tarr, P.I., Jardine, D, et al., Update: Multistate Outbreak of Escherichia coli O157:H7 Infections from Hamburgers -- Western United States, 1992-1993, MMWR, 42(14), 258-263, 16 Apr 1993
  • Jardine D S, An epidemic of hypoxemia in two intensive care units: cause and human response., Anesthesiology, 77(5), 1038-43, November 1992 Abstract
  • Bratton S L, Jardine D S, Cerebral infarction complicating hemorrhagic shock and encephalopathy syndrome., Pediatrics, 90(4), 626-8, October 1992 Abstract
  • Jardine DS, A mathematical model of life-threatening hyperthermia during infancy [published errata appear in J Appl Physiol 1993 Mar, Journal of Applied Physiology, 73(1), 329-39, July 1992 Abstract
  • Jardine DS, Haschke RH, An animal model of life-threatening hyperthermia during infancy, Journal of Applied Physiology, 73(1), 340-5, July 1992 Abstract
  • Jardine, DS and Costarino AT, Negative pressure ventilation for infants with respiratory failure after cardiac surgery, Paediatric Anaesthesia, 2, 45-50, 1992
  • Le Roux PD, Jardine DS, Kanev PM, Loeser JD, Pediatric intracranial pressure monitoring in hypoxic and nonhypoxic brain injury, Child's Nervous System, 7(1), 34-9, February 1991 Abstract
  • Jardine, DS, Re-expansion pulmonary edema, American Journal of Diseases of Children, 145, 1092-4, 1991
  • Jardine DS, Rogers K, Relationship of benzyl alcohol to kernicterus, intraventricular hemorrhage, and mortality in preterm infants, Pediatrics, 83(2), 153-60, February 1989 Abstract
  • Kovatch AL, Jardine DS, Dowling JN, Yee RB, Pasculle AW, Legionellosis in children with leukemia in relapse, Pediatrics, 73(6), 811-5, June 1984 Abstract
  • Friedman R, Zitelli B, Jardine D, Fireman P, Seizures in a patient receiving terbutaline, American Journal of Diseases of Children, 136(12), 1091-2, December 1982 Abstract
  • Emerson RG, Jardine DS, Milvenan ES, D'Souza BJ, Elfenbein GJ, Santos GW, Saral R, Toxoplasmosis: a treatable neurologic disease in the immunologically compromised patient, Pediatrics, 67(5), 653-5, May 1981 Abstract

Profile Details

Last Updated: 6/1/2009

COS Expertise ID #307604
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