Michigan State University College of Agriculture & Natural Resources Animal Science Laboratory of Developmental Epigenetics and Reproductive Biology Assistant ProfessorAppointed: 2007 | |
QualificationsPh.D., University of Massachusetts Amherst, Reproductive and Developmental Biology, 2002. Expertise and Research Interestsearly embryonic development, stem cells, epigenetics, calcium signaling Industrial RelevanceInfertility treatment, biotechnology, nuclear transfer in cattle KeywordsAdditional Terms:Developmental Biology, Epigenetics, Preimplantation.Languages(Reading, Writing, Speaking)English: (Fluent, Fluent, Fluent) MembershipsAmerican Society for Reproductive Medicine Gordon Research Conference Honors and Awards2006, Adjunct Assistant Professor,
Dr. Yi-Tao Zeng,
Shanghai Institute of Medical Genetics,
Reproductive Biology
Previous Positions2006-2007, Principal Investigator,
EMD-Serono, Inc.,
Reproductive Health
2005-2006, Post-doctoral fellow,
EMD-Serono, Inc.,
Reproductive Health
2003-2005, Post-doctoral fellow,
University of Pennsylvania,
Biology
Publications- Kidder B.L., Palmer S, Knott J.G. (2008) SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells, Stem Cells, 27 (2), 317-28
- Gardner AJ, Knott JG, Jones KT, Evans JP. (2007) CaMKII can participate in but is not sufficient for the establishment of the membrane block to polyspermy in mouse eggs., Journal of Cellular Physiology, 212 (2), 275-280
- Igarashi H, Knott JG, Schultz RM, Williams CJ (2007) Alterations of PLC beta1 in mouse eggs change calcium oscillatory behavior following fertilization, Developmental Biology, 312 (1), 321-30
- Knott JG, Gardner AJ, Madgwick S, Jones KT, Williams CJ, Schultz RM. (2006) Calmodulin-dependent protein kinase II triggers mouse egg activation and embryo development in the absence of Ca2+ oscillations., Developmental Biology, 296 (2), 388-395
- Malcuit C, Knott JG, He C, Wainwright T, Parys JB, Robl JM, Fissore RA. (2005) Fertilization and inositol 1,4,5-trisphosphate (IP3)-induced calcium release in type-1 inositol 1,4,5-trisphosphate receptor down-regulated bovine eggs., Biology of Reproduction, 73 (1), 2-13
- Ozil JP, Markoulaki S, Toth S, Matson S, Banrezes B, Knott JG, Schultz RM, Huneau D, Ducibella T. (2005) Egg activation events are regulated by the duration of a sustained [Ca2+]cyt signal in the mouse., Developmental Biology, 282 (1), 39-54
- Knott JG, Kurokawa M, Fissore RA, Schultz RM, Williams CJ. (2005) Transgenic RNA interference reveals role for mouse sperm phospholipase Czeta in triggering Ca2+ oscillations during fertilization., Biology of Reproduction, 72 (4), 992-996
- Knott JG, Kurokawa M, Fissore RA. (2003) Release of the Ca(2+) oscillation-inducing sperm factor during mouse fertilization., Developmental Biology, 262 (2), 536-547
- Fissore RA, Kurokawa M, Knott J, Zhang M, Smyth J. (2002) Mechanisms underlying oocyte activation and postovulatory ageing., Reproduction, 124 (6), 745-754
- Kuroiwa Y, Kasinathan P, Choi YJ, Naeem R, Tomizuka K, Sullivan EJ, Knott JG, Duteau A, Goldsby RA, Osborne BA, Ishida I, Robl JM. (2002) Cloned transchromosomic calves producing human immunoglobulin., Nature Biotechnology, 20 (9), 899-894
- Knott JG, Poothapillai K, Wu H, He CL, Fissore RA, Robl JM. (2002) Porcine sperm factor supports activation and development of bovine nuclear transfer embryos., Biology of Reproduction, 66 (4), 1095-1113
- Kasinathan P, Knott JG, Wang Z, Jerry DJ, Robl JM. (2001) Production of calves from G1 fibroblasts., Nature Biotechnology, 19 (12), 1176-1178
- Kasinathan P, Knott JG, Moreira PN, Burnside AS, Jerry DJ, Robl JM. (2001) Effect of fibroblast donor cell age and cell cycle on development of bovine nuclear transfer embryos in vitro., Biology of Reproduction, 64 (5), 1487-1493
Profile DetailsCOS Expertise ID #1275529 Individual Expertise profile of Jason Glenn Knott, Copyright Jason Glenn Knott. © COS Expertise TM, 2010, ProQuest LLC All rights reserved. |