Dr. Jane Sullivan

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University of Washington
School of Medicine
Physiology and Biophysics
Associate ProfessorAppointed: 2002
Professional Headshot of Jane Sullivan

Mailing Address

Department of Physiology and Biophysics
G424 Health Sciences Center
Box 357290
Seattle, Washington 98195-7290
United States

Contact Information

Phone: (206) 543-4038
Fax: (206) 685-0619
jmsull@u.washington.edu

Qualifications

Ph.D., University of Utah, Neuroscience, 1990.
B.A., Amherst College, Neuroscience, 1984.

Expertise and Research Interests

Molecular mechanisms mediating and modulating release of neurotransmitter

Keywords

COS Keywords:

Biophysics, Ion Channels, Neurobiology, Neuroscience, Neurotransmitters, Physiology, Synaptic Transmission.

Additional Terms:

Molecular Neurobiology, Neuroscience.

Memberships

Society for Neuroscience

Previous Positions

1999-2002, Senior Staff Scientist, Salk Institute for Biological Studies, Molecular Neurobiology Laboratory
1999-2002, Assistant Adjunct Professor, University of California, San Diego, School of Medicine, Neurosciences
1997-1999, Staff Scientist, Salk Institute for Biological Studies, Molecular Neurobiology Laboratory
1994-1997, Research Associate, Salk Institute for Biological Studies, Molecular Neurobiology Laboratory, Stevens Lab
1990-1994, Research Associate, Salk Institute for Biological Studies, Molecular Neurobiology Laboratory, Heinemann Lab

Funding Received

  • American Health Assistance Foundation (AHAF): Role of Presenilin in Synaptic Transmission, 2007 to 2009.
  • National Institutes of Health (NIH): Mechanisms of Synapse Dysfunction in Alzheimer's Disease, 2007 to 2011.
  • UWSOM Alzheimer's Disease Related Research Grant: Mechanisms of Synapse Dysfunction in Alzheimer's Disease, 2006 to 2008.
  • Alzheimer's Disease Research Center (ADRC): Cellular and Molecular Mechanisms Underlying APP-Mediated Synaptic Dysfunction, 2006 to 2007.
  • Klingenstein Foundation: Synaptic Vesicle Protein Synaptotagmin IV, 2004 to 2007.
  • Whitehall foundation: How Does Synaptotagmin Control Fast Synaptic Transmission?, 2003 to 2005.
  • National Institutes of Health (NIH): Cannabinoid Effects on Synaptic Function and Plasticity, 1998 to 2003.

Publications

  • Sullivan JM (Jan 2007) A simple depletion model of the readily releasable pool of synaptic vesicles cannot account for paired-pulse depression., Journal of Neurophysiology, 97 (1), 948-50 Abstract
  • Ting JT, Kelley BG, Lambert TJ, Cook DG, Sullivan JM (Jan 2007) Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms., Proceedings of the National Academy of Sciences of the United States of America, 104 (1), 353-8 Abstract
  • Ting JT, Kelley BG, Sullivan JM (Jan 2006) Synaptotagmin IV does not alter excitatory fast synaptic transmission or fusion pore kinetics in mammalian CNS neurons., The Journal of Neuroscience, 26 (2), 372-80 Abstract
  • Custer KL, Austin NS, Sullivan JM, Bajjalieh SM (Jan 2006) Synaptic vesicle protein 2 enhances release probability at quiescent synapses., The Journal of Neuroscience, 26 (4), 1303-13 Abstract
  • Borden CR, Stevens CF, Sullivan JM, Zhu Y (Jul 2005) Synaptotagmin mutants Y311N and K326/327A alter the calcium dependence of neurotransmission., Molecular and Cellular Neurosciences, 29 (3), 462-70 Abstract
  • Stevens CF, Sullivan JM, The synaptotagmin C2A domain is part of the calcium sensor controlling fast synaptic transmission, Neuron, 39(2), 299-308, 2003 Abstract
  • Stevens CF, Sullivan JM (Jul 2003) The synaptotagmin C2A domain is part of the calcium sensor controlling fast synaptic transmission., Neuron, 39 (2), 299-308 Abstract
  • Straiker AJ, Borden CR, Sullivan JM (Apr 2002) G-protein alpha subunit isoforms couple differentially to receptors that mediate presynaptic inhibition at rat hippocampal synapses., The Journal of Neuroscience, 22 (7), 2460-8 Abstract
  • Sullivan JM, Cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids, Learning & Memory (Cold Spring Harbor, NY), 7(3), 132-9, 2000
  • Sullivan JM, Mechanisms of cannabinoid-receptor-mediated inhibition of synaptic transmission in cultured hippocampal pyramidal neurons, Journal of Neurophysiology, 82(3), 1286-94, 1999 Abstract
  • Sullivan JM (Sep 1999) Mechanisms of cannabinoid-receptor-mediated inhibition of synaptic transmission in cultured hippocampal pyramidal neurons., Journal of Neurophysiology, 82 (3), 1286-94 Abstract
  • Misner DL, Sullivan JM (Aug 1999) Mechanism of cannabinoid effects on long-term potentiation and depression in hippocampal CA1 neurons., The Journal of Neuroscience, 19 (16), 6795-805 Abstract
  • Stevens CF, Sullivan JM, Regulation of the readily releasable vesicle pool by protein kinase C, Neuron, 21(4), 885-93, 1998 Abstract
  • Stevens CF, Sullivan JM (Oct 1998) Regulation of the readily releasable vesicle pool by protein kinase C., Neuron, 21 (4), 885-93 Abstract
  • Choe S, Stevens CF, Sullivan JM (Dec 1995) Three distinct structural environments of a transmembrane domain in the inwardly rectifying potassium channel ROMK1 defined by perturbation., Proceedings of the National Academy of Sciences of the United States of America., 92 (26), 12046-9 Abstract
  • Sullivan JM, Traynelis SF, Chen HS, Escobar W, Heinemann SF, Lipton SA, Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor, Neuron, 13(4), 929-36, 1994 Abstract
  • Sullivan JM, Traynelis SF, Chen HS, Escobar W, Heinemann SF, Lipton SA (Oct 1994) Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor., Neuron, 13 (4), 929-36 Abstract

Profile Details

Last Updated: 12/10/2008

COS Expertise ID #1015873
Reference this profile directly: http://myprofile.cos.com/jmsullivan