Dr. Kate Claycombe

powered by
COS Expertise®
Michigan State University
College of Natural Science
Food Science and Human Nutrition
Assistant Professor

Mailing Address

G. Malcolm Trout Building
Room 302A
East Lansing, Michigan 48824-1224
United States

Contact Information

Phone: (517) 355-8474, ext. 133
Fax: (517) 353-8963
claycom3@msu.edu

Qualifications

Ph.D., University of Tennessee, Nutritional Science, 1999.

Expertise and Research Interests

Obesity
Nutritional Biochemistry
Nutrient Regulation of Gene Expression
Nutritional Immunology

Keywords

COS Keywords:

Agriculture and Food Sciences, Biochemical Markers, Biochemistry, Biological Markers, Blood Coagulation, Cell Biology, Cell Differentiation, Cell Interactions, Cholesterol, Cytokines, Diseases and Disorders, Food Sciences, Genetics, Growth Factor Receptors, Health and Medicine, Human Genome, Immunology, Life Sciences, Lipoproteins, Lymphocytes, Membranes, Metabolic Biology, Micronutrients, Molecular Biology, Molecular Cellular Entities, Molecular Genetics, Nutrition or Dietetics, Obesity, Physiology, Prostaglandins, Recombinant DNA, Signal Transduction, Stem Cells, Thermoregulation.

Additional Terms:

Nutritional Biochemistry, Nutritional Immunology, Obesity.

Memberships

American Society for Nutritional Sciences

Honors and Awards

2005-2006, Project Green, Michigan State Agricultural Experimental Station
2004-2005, Research Grant, Cherry Marketing Institute
2002-2007, Multistate Regional Project, USDA N-3 Polyunsaturated fatty acids and Human Health
2002-2003, ROIP research seed grant, College of Human Ecology, Michigan State University

Previous Positions

1999-2001, Scientist III, Tufts University, JM USDA/HNRCA, Nutritional Immunology Lab

Publications

  • Zhou HR, Kim EK, Kim H, Claycombe KJ (Nov 2007) Obesity-associated mouse adipose stem cell secretion of monocyte chemotactic protein-1., American journal of physiology. Endocrinology and metabolism, 293 (5), E1153-8 Abstract
  • Harkins JM, Moustaid-Moussa N, Chung YJ, Penner KM, Pestka JJ, North CM, Claycombe KJ (Oct 2004) Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice., The Journal of nutrition, 134 (10), 2673-7 Abstract
  • Wang Y, Jones Voy B, Urs S, Kim S, Soltani-Bejnood M, Quigley N, Heo YR, Standridge M, Andersen B, Dhar M, Joshi R, Wortman P, Taylor JW, Chun J, Leuze M, Claycombe K, Saxton AM, Moustaid-Moussa N (May 2004) The human fatty acid synthase gene and de novo lipogenesis are coordinately regulated in human adipose tissue., The Journal of nutrition, 134 (5), 1032-8 Abstract
  • Wu D, Marko M, Claycombe K, Paulson KE, Meydani SN, Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity, Journal of Bioligical Chemistry, 278(13), 10983-92, March 2003 Abstract
  • Heo YR, Claycombe K, Jones BH, Wright P, Truett GE, Zemel M, Banz W, Maher M, Moustaid-Moussa N, Effects of fatty (fa) allele and high-fat diet on adipose tissue leptin and lipid metabolism, Hormone and Metabolic Research. Hormon- Und Stoffwechselforschung. Hormones Et Metabolisme., 34(11-12), 686-90, 2002 Abstract
  • Claycombe KJ, Wu D, Nikolova-Karakashian M, Palmer H, Beharka A, Paulson KE, Meydani SN, Ceramide mediates age-associated increase in macrophage cyclooxygenase-2 expression, Journal of Bioligical Chemistry, 277(34), 30784-91, Aug 2002 Abstract
  • Kim S, Dugail I, Standridge M, Claycombe K, Chun J, Moustaid-Moussa N, Angiotensin II-responsive element is the insulin-responsive element in the adipocyte fatty acid synthase gene: role of adipocyte determination and differentiation factor 1/sterol-regulatory-element-bi, Biochemical Journal, 357(Pt 3), 899-904, 2001 Abstract
  • Claycombe KJ, Meydani SN, Vitamin E and genome stability, Mutation Research, 475(1-2), 37-44, April 2001 Abstract
  • Claycombe KJ, Wang Y, Jones BH, Kim S, Wilkison WO, Zemel MB, Chun J, Moustaid-Moussa N, Transcriptional regulation of the adipocyte fatty acid synthase gene by agouti: interaction with insulin, Physiological Genomics [computer File], 3(3), 157-62, 2000 Abstract
  • Claycombe KJ, Xue BZ, Mynatt RL, Zemel MB, Moustaid-Moussa N, Regulation of leptin by agouti, Physiological Genomics [computer File], 2(3), 101-5, 2000 Abstract
  • Moussa NM, Claycombe KJ, The yellow mouse obesity syndrome and mechanisms of agouti-induced obesity, Obesity Research, 7(5), 506-14, September 1999 Abstract
  • Jones BH, Standridge MK, Claycombe KJ, Smith PJ, Moustaid-Moussa N, Glucose induces expression of stearoyl-CoA desaturase in 3T3-L1 adipocytes, Biochemical Journal, 335 ( Pt 2), 405-8, 1998 Abstract
  • Claycombe KJ, Jones BH, Standridge MK, Guo Y, Chun JT, Taylor JW, Moustaid-Moussa N, Insulin increases fatty acid synthase gene transcription in human adipocytes, The American Journal of Physiology, 274(5 Pt 2), R1253-9, May 1998 Abstract
  • Claycombe KJ, Lee DW, Miller HA, Proportions of rat ANP-secreting cells that are cardiomyocytes and that synthesize the hormone, American Journal of Physiology, 268(1 Pt 2), H265-70, January 1995 Abstract
  • Heo YR, Claycombe K, Jones BH, Wright P, Truett GE, Zemel M, Banz W, Maher M, Moustaid-Moussa N, Effects of fatty (fa) allele and high-fat diet on adipose tissue leptin and lipid metabolism., Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et métabolisme, 34 (11-12), 686-90 Abstract

Profile Details

Last Updated: 1/20/2008

COS Expertise ID #973877
Reference this profile directly: http://myprofile.cos.com/kateclaycombe