Dr. Kotamballi N. Chidambara Murthy |
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Texas A&M University Texas Agricultural Extension Service VFIC Horticulture Sciences Postdoctoral FellowAppointed: 2006 |  |
Mailing Address1500 Centeq Research Plaza Research Parkway Suite 120A College Station, Texas 77845-2119United States | Contact Information |
Qualifications
Ph.D., Central Food Technological Research Institute, Biotechnology, 2005.
Dip in R and D, AIIMAT, 2001.
Master in Pharmacy, Government College of Pharmacy, Pharmacognosy and Phytochemistry, 2001.
B.Pharma, JSS college of Pharmacy, Pharmaceutical Sciences, 1997.
Expertise and Research Interests
Have an year's experience in the production and planning department at a reputed Pharmaceutical Industry and one year teaching experience in a pharmacy college. Apart from research experience, have idea of writing patents, projects and process of pharmaceutical and nutraceutical significance.
Aim to build a career in the area of Research and Development by learning various skills to explore newer dimensions in the frontier areas of life science involving biotechnology and medicine in general, Phytochemistry and phytomedicine related area in particular. Ready to take up any new and challenging program that can lead to better R and D prospects.
Aim to build a career in the area of Research and Development by learning various skills to explore newer dimensions in the frontier areas of life science involving biotechnology and medicine in general, Phytochemistry and phytomedicine related area in particular. Ready to take up any new and challenging program that can lead to better R and D prospects.
Other Expertise
Development of biotechnological methodology for cultivation of micro algae
Standardization of conditions for production of optimum carotenoids
Make algae suitable for growth in different geographical conditions out door
Isolation and characterization of various carotenoids
Evaluation of biological activities of the same by In vitro and In vivo models
Application of animal cell lines for the biological activity studies
Studies on molecular responses of carotenoids biosynthesis in response to various drugs and chemicals
Isolation and separation of key enzymes of interest from Algae
Algal biotechnology and pharmacology
Pharmacological screening of compounds, like in vivo antioxidant activity, hepatoprotective activity, anti ulcer, wound healing and screening for other cardiovascular pharmacological activities.
Modern analytical techniques like, column chromatography, HPLC, GC, GC-MS, LC-MS utilized for activity guided isolation and characterization of bioactive and nutraceutical molecules from plants, algae and sea vegetables.
Isolation and characterization of algal proteins, nutritional analysis and bioavailability studies in vitro, molecular biology techniques and biochemical techniques like enzyme isolation and purification, animal genetics and plant genetics.
Standardization of conditions for production of optimum carotenoids
Make algae suitable for growth in different geographical conditions out door
Isolation and characterization of various carotenoids
Evaluation of biological activities of the same by In vitro and In vivo models
Application of animal cell lines for the biological activity studies
Studies on molecular responses of carotenoids biosynthesis in response to various drugs and chemicals
Isolation and separation of key enzymes of interest from Algae
Algal biotechnology and pharmacology
Pharmacological screening of compounds, like in vivo antioxidant activity, hepatoprotective activity, anti ulcer, wound healing and screening for other cardiovascular pharmacological activities.
Modern analytical techniques like, column chromatography, HPLC, GC, GC-MS, LC-MS utilized for activity guided isolation and characterization of bioactive and nutraceutical molecules from plants, algae and sea vegetables.
Isolation and characterization of algal proteins, nutritional analysis and bioavailability studies in vitro, molecular biology techniques and biochemical techniques like enzyme isolation and purification, animal genetics and plant genetics.
Future Research
Wish take up new and challenging programs in the area of Nutracetucal and health related reseach.
Industrial Relevance
Worked in Bangalore Pharmaceutical Research Laboratory as a production and planning chemist for a year in the capsule and semisolids formulation division.
Keywords
COS Keywords:
Pharmaceuticals.Additional Terms:
Bioacive Compounds, Biological Activity of Natural Compounds, Nutraceuticals, Phytochemicals.Languages
(Reading, Writing, Speaking)
English: (Fluent, Fluent, Fluent)
Kannada (Regional Language of India): (Fluent, Fluent, Fluent)
Hindi (Indian National Language): (Fluent, Fluent, Functional)
Telugu (Regional Language of India): (Functional, Basic, Functional)
Tamil (Regional Language of India): (None, None, Functional)
Memberships
AMI-India
International Carotenoids Society
SBC(I)
State Pharmacy Council-Karnataka, India
Honors and Awards
2002-2006,
Senior Research Fellowship,
CSIR, India,
Medical and Health Sciences
1993-1997,
Prathibha-1998,
JSS educational institutions, Mysore, India,
Education
Travel grant fellowship-2005,
Department of Science and Technology,
Government of India,
Biotechnology
Best Poster award,
AFST,
CFTRI,
Best poster in the area of Functional foods
Travel grant fellowship,
Karnataka State Pharmacy council,
Pharmaceutical sciences
Best Presentation,
AMI-Mysore division,
Research scholars presentation
Previous Positions
2002-2006, Research Fellow,
Central Food technological Research Institute,
CFTRI,
Plant Cell Biotechnology,
Algal Biotechnology
2001-2002, Lecturer,
Farooquia College of Pharmacy,
FCP,
Phytochemisttry and Pharmacognosy
1998-1999, Trainee Production and Planning Chemist,
Bangalore Pharmaceutical Research ltd.,,
Capsule and Semi Solid Dosage Forms
Patents
A process for the preparation of antioxidant activity rich extracts of tuberous roots of D. hemiltonii,
Patent Number: WO/2005/063272,
2005,
Institution,
United States.
Seawater based medium for the production of Spirulina,
Patent Number: NF-281/04,
2004,
Institution,
India.
A modified medium for producing the Dunaliella species for production of - carotene.,
Patent Number: 585/DEL/2004,
2004,
Institution,
India.
An improved formulation for the stabilization of Natural color in cough syrup.,
Patent Number: NF 184/03,
2003,
Institution,
India.
Publications
- K N.Chidambara Murthy, G. K. Jayaprakasha (2008) Induction of apoptosis mediated cytotoxicity by Obacunone and its glucoside in human prostate carcinoma cells, ACS Spring 2008 -New Orleans, American Chemical Society, ACS Publications
- Jeevitha B. Patil, , K N.Chidambara Murthy, G. K. Jayaprakasha (2008) Marroon carrot extracts induce apoptosis in human breast cancer cells, ACS Spring 2008, American Cehmical Society, ACS Publishers
- Kotamballi N Chidambara Murthy et al., (2007) Blocking of Sterol Biosynthesis by Statin Enhances Carotenoid Production in Dunaliella, Functional Plant Science and Biotechnology, 361-365
- K.N.Chidambara Murthy, G.K.Jayaprakasha, Stephen Safe, Bhimu Patil (2007) Potential of citrus limonoids in pancreatic cancer prevention, ACS 234th Meeting Boston, American Chemica Society, ACS, Unpublished
- K. N. Chidambara Murthy, , G. K. Jayaprakasha, Stephen H. Safe, Bhimanagouda S. Patil (2007) Potential of citrus limonoids in pancreatic cancer prevention, ACS-Fall 2007 Boston, ACS, ACS Publishers
- Jaiprakash R. Patil, G.K. Jayaprakasha, K N.Chidambara Murthy (2007) Kagzi lime (Citrus aurantifolia Swingle) volatile oil - a potential source for colon cancer prevention., ACS-Fall 2007 Boston, American Chemical Society, ACS publishers
- K N.Chidambara Murthy (2007) Pomegranate fractions may prevent prostate cancer, ACS Fall 2007, Boston, American Chemical Society, ACS Publishers
- G. K. Jayaprakasha, K. N.Chidambara Murthy (2007) Volatile oil from Sour oranges (Citrus aurantium L.) has potential benefit in colon cancer prevention, ACS Fall 2007, Boston, Amrican Chemical Society, ACS publishers
- K.N.Chidambara Murthy, G.K.Jayaprakasha, Lianardo Pike, Bhimu Patil (2007) Colon cancer preventive Effect of BeetaSweet carrot, ASHS, American Society of horticulture Sceinces, Arizona, ASHS-2007, Unpublished
- A. Vanitha, K.N.Chidambara Murthy et al., (2007) Comparative study of lipid composition of two halotolerant alga, Dunaliella bardawil and Dunaliella salina, International Journal of Food Science and Nutrition, 58 (5), 373-382
- Vanitha A., K.N.Chidambara Murthy et al., (2007) Effect of the Carotenoid-Producing Alga, Dunaliella bardawil, on CCl4-Induced Toxicity in Rats, International Journal of Toxicology, 26 (2), 159-167
- Kotamballi N. Chidambara Murthy, Gokare A.Ravishankar (2007) Microalgal research Golbal Scenario, Ist Edition, Vol. 2, "Carotenoids from Dunaliella -A journey from test-tube to customer", CSMCRI, Bhavanagar, India, CSMCRI, Bhavanagar, India, 157 pages
- K.N.Chidambara Murthy, G.K.Jayaprakasha, Bhimu Patil (2007) Inhibition of colon cancer by limonin and its glucoside involves regulation of Bcl2/Bax, FAV-2007, ASHS
- Chidambara Murthy, K. N. et al., (2006) Antioxidant property of Decalepis hamiltonii Wight & Arn, Indian Journal of Experimental Biology, 44 (10), 832-837
- Rajesh J, Chidambara Murthy, K. N. et al., (2006) Antioxidant Potentials of Flaxseed by in Vivo Model, Journal of Agriculture and Food Chemistry, 54 (11), 3794 - 3799
- K.N.Chidambara Murthy and G.A. Ravishankar (2006) Carotenoids from Dunaliella -A journey from test-tube to customer, For algal data series CSMCRI, Gujarat, India.
- Chidambara Murthy, K. N. et al., (2005) Comparative Evaluation of Hepatoprotective Activity of Carotenoids of Microalgae, Journal of Medicinal Food Dec, 8 (4), 523-528
- K.N.Chidambara Murthy (2005) Micro algae, potential sources of carotenoids-Invited talk, Symposium on Nutraceuticals and Biotechnology, India, GRD College of Science, Coimbatore,
- K.N.Chidambara Murthy (2005) Herbal pharmaceuticals- Biotechnological Interventions, Training course for professional medical officers, Atrimed Pharmaceutcals Ltd.,
- K.N.Chidambara Murthy, G.A.Ravishankar (2005) Biologically efficient carotenoids from micro algae Dunaliella presented, 14th International symposium on carotenoids, International Carotenoids Society, United Kingdom, International Carotenoids Society
- Laurent Dufosse, Galaup P, Yaron A, Arad MS, Blanc P, Chidambara Murthy KN, Ravishankar GA. (2005) Microorganisms and algae as source of pigments for food use: a scientific oddity or an industrial reality?, Trends in Food Science and Technology, 16 (389), 406
- K.N.Chidambara Murthy (2005) Production of pharmacologically efficient carotenoids from micro algae-Invited talk, Phytopharma 2005, Phytopharma
- Fayaz M, Chidambara Murthy K.N et al., (2005) Chemical Composition, Iron Bioavailability, and Antioxidant Activity of Kappaphycus alvarezzi (Doty), Journal of Agriculture and Food Chemistry, 53 (3), 792 -797
- N. Bhagyalakshmi, R.Thimmaraju, L.Venkatachalam, K. N. Chidambara Murthy and R. V Sreedhar. (2005) Applications of Garlic and the Intervention of Biotechnology, Critical Reviews in Food Science and Nutrition., 45, 607-621
- Vinod K, Chidambara Murthy, K. N. et al., (2005) Genetically modified hairy roots of Withania, Rejuvenation Research, 8, 37-45
- Chidambara Murthy, K. N. et al., (2005) In vivo antioxidant activity of carotenoids from Dunaliella salina: a green microalga, Life Sciences, 76 (12), 1381-1390
- Chidambara Murthy, K. N. et al., (2005) Protective effect of Dunaliella salina : A marine micro alga, against carbon tetrachloride-induced hepatotoxicity in rats, Hepetology Research, 33 (4), 313-319
- K.N.Chidambara Murthy, P.R.Sowmya, A .Vanitha, M. Mahadeva Swamy, G.A.Ravishankar (2004) Nutritional properties of micro algae Dunaliella salina, National symposium on protein (Solae), SOLAE-CFTRI, Mysore, India, CFTRI, Mysore
- K.N.Chidambara Murthy, P.R.Sowmya, A Vanitha, M Mahadeva Swamy, G.A.Ravishankar (2004) Flocculation- a simple technique to harvest micro alga Dunaliella salina., National symposium on Microalgal Biotechnology, India, Bharthidasan University, Tiruchirapally
- K.N.Chidambara Murthy (2004) Micro algae- a potential source of bioactive compounds-Talk, National symposium on Microalgal Biotechnology,
- Chidambara Murthy, K. N. et al. (2004) Study on wound healing activity of Punica granatum peel, Journal of Medicinal Food, 7 (2), 256-259
- Chidambara Murthy, K. N. et al., (2003) Antioxidant and Antimicrobial Activity of Cissus quadrangularis L., Journal of Medicinal Food, 06 (02), 99-105
- K. N. Chidambara Murthy,, Jyothi. M.Veigas, Uma D.Murthy (2002) Formulation and evaluation of water based gel from Pomegranate methanol extract, 51st -Indian Pharmaceutical Congress, Indian Pharmaceutical association, IPC, Mumbai, India
- K.N.Chidambara Murthy, A.Vanitha, Mahadeva Swamy, R Sarada, G.A.Ravishankar (2002) Antioxidant activity of Dunaliella salina extracts, Indian Convention of Food Science and Technologists -2002, ICFOST, CFTRI, Mysore, India, ICFOST-2002
- K.N.Chidambara Murthy (2002) Edible vaccines- Technology and applications, Association of Microbiologist India (AMI). Lecture competition, AMI-Mysore Chapter
- Chidambara Murthy, K. N. et al. (2002) Antioxidant Activities of Grape (Vitis vinifera) Pomace Extracts, Journal of Agriculture and Food Chemistry, 50 (21), 5909-5914
- Chidambara Murthy, K. N. et al. (2002) Studies on Antioxidant Activity of Pomegranate (Punica granatum) Peel Extract Using in Vivo Models, Journal of Agriculture and Food Chemistry, 50 (17), 4791-4795
- R.P.Singh, Chidambara Murthy, K. N. and G.K. Jayaprakasha (2001) Studies on the Antioxidant Activity of Pomegranate (Punica granatum) Peel and Seed Extracts Using in Vitro Models, Journal of Agriculture and Food Chemistry, 50 (1), 81-86
- K.N.Chidambara Murthy, R.P.Singh, Uma D Murthy (2000) Antioxidative activity of extracts from pomace of grape Vitis vinifera), Indian Convention of Food Science and Technologists-2000, ICFOST-2000, Mysore, India, ICFOST-2000
- Jyothi M Veigas., M.S.Narayan .,K.N.Chidambara Murthy., B.Neelawarne, Antioxidative Efficacies of Floral Petal Extracts of Delonix Regia Rafin, International Journal of Biomedical and Pharmaceutical Sciences, 2007, In Press
- Kotamballi N Chidambara Murthty, Gokare A Ravishankar, National symposium on Microalgal biotechnology-proceedings, Micro algae - a potential source of bioactive compounds", Bharthidasan University, Tiruchirappali, India., In Press
- K.N.Chidambara Murthy, Inhibition of colon cancer by limonin and its glucoside involves regulation of Bcl2/Bax, FAV-2007, ASHS
- B.S.Patil, G.K.Jayaprakasha, K.N.Chidambara Murthy, Citrus Bioactive Natural Compounds and their Potential for Cancer Prevention, 2nd International Symposium on Translational Research-Natural product and Cancer, Society for Translational Cancer Research
Profile Details
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COS Expertise ID #1261050
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