Larry W. Robertson

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University of Iowa
College of Public Health
Occupational & Environmental Health
ProfessorAppointed: 2003
University of Iowa
College of Public Health
Occupational & Environmental Health
Toxicology and Oxidative Stress Research Core
Co-DirectorAppointed: 2004
University of Iowa
College of Public Health
Occupational & Environmental Health
Environmental Health Sciences Research Center
Director, Pilot Grant ProgramAppointed: 2003
University of Iowa
Carver College of Medicine
Medicine Administration
Full MemberAppointed: 2003
Professional Headshot of Larry W. Robertson

Mailing Address

Department of Occupational and Environmental Health
100 Oakdale Campus #219 IREH
University of Iowa
College of Public Health
Iowa City, Iowa 52242-5000
United States

Contact Information

Phone: (319) 335-4554
Fax: (319) 335-4290
larry-robertson@uiowa.edu
http://www.public-health.uiowa.edu/faculty-staff/faculty/directory/faculty-detail.asp?emailAddress=larry-robertson@uiowa.edu

Qualifications

Ph.D., University of Michigan, Environmental Health Sciences, 1981.
M.P.H., University of Michigan, Public Health, 1972.
M.S., University of Florida, Microbiology, 1971.
B.A., Stetson University, Chemistry, 1969.

Expertise and Research Interests

My primary area of research is the mechanism(s) of toxicity of polyhalogenated aromatic hydrocarbons. Members of this class include the polychlorinated biphenyls (PCBs), dibenzodioxins, dibenzofurans and various pesticides. My research on these environmental pollutants includes studies of their effects on gene regulation, their metabolism to electrophilic species and their binding to nucleophiles, including amino acids, nucleotides and DNA. My recent research has demonstrated that, during the metabolism of PHAHs, oxidative events occur which lead to increased oxidative DNA damage.

Other Expertise

I have contributed the following book chapters:

  • Robertson LW, Gupta RC. Chapter 2: Metabolism of polychlorinated biphenyls (PCBs) generates electrophiles and reactive oxygen species that damage DNA. In: Molecular Drug Metabolism and Toxicology, GM Williams and OI Aruoma, Eds. London: OICA International Limited, 2000
  • Schwarz M, Buchmann A, Robertson LW, Kunz W. Cell proliferation and hepatocarcinogenesis. In: Scientific Issues in Quantitative Cancer Risk Assessment, Moolgavkar, Ed. Boston: Birkhauser, 1990
  • Puttman M, Arand M, Oesch F, Mannschreck A, Robertson LW. Chirality and the induction of xenobiotic-metabolizing enzymes: Effects of the atropisomers of the polychlorinated biphenyl 2,2',3,4,4',6-hexachlorobiphenyl. In: Chirality and Biological Activity, Homstedt, Frank, and Testa, Eds. New York: Alan R. Liss, Inc., 1990
  • Timms C, Schladt L, Robertson LW, Rauch P, Schramm H, Oesch F. The regulation of rat liver epoxide hydrolases in relation to that of other drug-metabolizing enzymes. In: Drug Metabolism - from Molecules to Man, Benford, Bridges, and Gibson, Eds. London: Taylor and Francis, 1987
  • Robertson LW, Arand M, Okamoto Y, Puttmann M, Rauch P, Schramm H. Comments on the regulation of carcinogen metabolizing enzymes. In: Primary Changes andControl Factors in Carcinogenesis, Friedberg and Oesch, Eds. Wiesbaden: Deutscher Fachschriften-Verlag, 1986
  • Safe S, Robertson LW, Sawyer T, Bandiera S, Safe L, Parkinson A, Campbell MA, Mullin M. PCBs: Structure-activity Relationships. In: Advances inExposure, Health and Environmental Effects Studies of PCBs: Symposium Proceedings. NTIS Accession No. PB84-135771 1982
  • Safe S, Parkinson A, Robertson LW, Bandiera S, Sawyer T, Safe L, Lambert I, Andres J, Campbell MA. Halogenated biphenyls as AHH inducers: Effects of different halogen substituents.. In: Cytochrome P-450, Biochemistry, Biophysics and Environmental Implications, Hietanen and Laitinen, Eds. Elsevier Biomedical Press, 1982
  • Safe S, Robertson LW, Sawyer T, Parkinson A, Bandiera S, Safe L, Campbell MA. PCDDs and related compounds: Metabolism and biochemistry. In: Human and Environmental Risks of Chlorinated Dioxins and Related Compounds, Tucker, Young, and Gray, Eds. New York: Plenum Press, 1983
  • Safe S, Parkinson A, Robertson LW, Safe L, Bandiera S. Polychlorinated biphenyls: Effects of structure on biological and toxic activity. In: Workshop on the Combined Effects of Xenobiotics, Stich, Leung, and Roberts, Eds. Ottawa: National Research Council. 1982
  • Safe S, Parkinson A, Robertson LW,Cockerline R, Safe L, Bandiera S, Okey A. PCBs and AHH Inducers. In: Chlorinated Dioxins and Related Compounds: Impact on the Environment, Hutzinger, Frie, Merian, and Pocchiari, Eds. New York: Pergamon Press, 1982
  • Safe S, Robertson LW, Parkinson A, Shilling M, Cockerline R, Campbell MA. Polybrominated biphenyls, polychlorinated naphthalenes and polychlorinated terphenyls as microsomal enzyme inducers. In: Toxicology of Halogenated Hydrocarbons: Health and Ecological Effects, Khan and Stanton, Eds. NewYork: Pergamon Press, 1981
  • Safe S, Parkinson A, Robertson LW, Cockerline R, Safe L. PCBs as microsomal enzyme inducers: Structure-activity rules. In: Toxicology of Halogenated Hydrocarbons: Health and Ecological Effects, Khan and Stanton, Eds. New York: Pergamon Press, 1981
  • Parkinson A, Cockerline R, Robertson LW, Safe S. Induction of cytochrome P-448 and P-450 by PCB isomers and congeners. In: Microsomes, Drub Oxidations and Chemical Carcinogenesis, Volume 1, Coon, Conney, Estabrook Gelcoin, Gillette, and Obrian, Eds. New York: Academic Press, 1980
  • Strik JJTWA, Doss M, Schraa G, Robertson LW, von Tipermann R, Harmsen EGM. Coproporphyrinuira and chornic hepatic porphyria type A found in farm families from Michigan (USA) exposed to polybrominated biphenyls (PBB). In: Chemical Porphyria in Man, Strik and Koeman, Eds. Elsevier, 1979

Keywords

COS Keywords:

Cancer or Carcinogenesis, Consulting Services, DNA, Environmental Health, Environmental Toxicology, Microbiology, Occupational Health and Safety, Public Health, Toxicology.

Additional Terms:

Liver Effects (Hepatotoxicity), Metabolism of Environmental Pollutants, Persistent Orgaic Pollutants (POPs), Pesticides, Polychlorinated Biphenyls (PCBs), Stockholm Convention.

Languages

(Reading, Writing, Speaking)

German: (Functional, Functional, Fluent)

Memberships

American Association for Cancer Research
American Chemical Society
Delta Phi Alpha
Deutsche Gesellschaft fur Pharmakologie und Toxikologie
Gamma Sigma Epsilon
Sigma Xi, The Scientific Research Society
Society of Toxicology

Previous Positions

1996-2003, Professor, University of Kentucky, Graduate Center for Toxicology
1986-1996, Associate Professor, University of Kentucky, Graduate Center for Toxicology
1983-1986, Alexander von Humboldt Research Fellow, , Research with Professor F. Oesch
1981-1982, Research Associate, Texas A&M University
1978-1981, Research Assistant, University of Guelph
1976-1976, Self-Employed Consultant, Lake Nasser-Rive Nile Project in Cairo, Egypt

Funding Received

  • Department of the Army: Principal Investigator, Mechanisms of PCBs-Induced Breast Cancer, $518,996, Sep 1996 to Sep 2000.
  • Environmental Protection Agency (EPA): Principal Investigator, Cooperative agreement for risk assessment research related to halogenated hydrocarbons, $39,054, Oct 1992 to Mar 1994.
  • Department of the Army: Co-Investigator, Dietary Lipids, Cell Adhesion and Breast Cancer Metastatis, M. Toborek, PI, $305,550, Oct 1999 to Oct 2003.
  • University of Kentucky: Principal Investigator, Super Fund Basic Reserach Program, $169,913, May 1, 2003 to Mar 31, 2004.
  • North Atlantic Treaty Organization (NATO): Principal Investigator, Studies on vitamin A-xenobiotic interactions, $5,940, Jul 15, 1989 to Dec 31, 1991.
  • National Institutes of Health (NIH): Principal Investigator, Research Training in Environmental Toxicology, $167,528/year, Jul 2000 to Jun 2005.
  • National Institutes of Health (NIH): Principal Investigator, Research training in environmental toxicology, $150,000/year, Jul 1995 to Jun 2000.
  • National Institutes of Health (NIH): Principal Investigator, Research training in environmental toxicology, $188,000, Jul 1990 to Jun 1995.
  • North Atlantic Treaty Organization (NATO): Principal Investigator, Studies on vitamin A-xenobiotic interactions, $4,947, Jan 1, 1992 to Dec 20, 1993.
  • National Institutes of Health (NIH): Co-Investigator, Enzyme induction defect: Implication for toxicity, R. Blouin, PI, $108,000, Jan 1990 to Dec 1992.
  • United States Department of Agriculture (USDA): Principal Investigator, National Need Graduate Fellowships in Human Nutrition, $169,000, Dec 1999 to Dec 2003.
  • National Institutes of Health (NIH): Principal Investigator, Training Program in Oxidative Stress and Nutrition, $75,137/year, Aug 15, 2000 to Jul 31, 2005.
  • United States Department of Defense (DOD): Co-Investigator, Prostate Cancer Risk through Exposure to Hologenated Hydrocarbons and Modulation by Dietary Supplementation, G. Ludewig, PI, $325,790, Apr 1, 2002 to Apr 30, 2005.
  • National Institutes of Health (NIH): Principal Investigator, Mechanisms of carcinogenesis: Halogenated biphenyls, $277,586, Apr 1, 1993 to Mar 31, 1996.
  • National Institutes of Health (NIH): Principal Investigator, Superfund Chemicals: Transport, Metabolism and Toxicity, $10,502,197, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Principal Investigator, Activation of PCBs to genotoxins in vivo (Project #1 of Superfund Chemicals: Transport, Metabolism and Toxicity), $181,935 Year 1, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Co-Investigator, Superfund chemicals and endothelial cell dysfunction, B. Hennig, PI (Project #2 of Superfund Chemicals: Transport, Metabolism and Toxicity), $129,033 Year 1, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Co-Investigator, PCBs, ICAM-1 expression and cancer metastasis, $98,854 Year 1, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Principal Investigator, Administrative Core (Core Project A in Superfund Chemicals: Transport, Metabolism and Toxicity), $59,587 Year 1, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Principal Investigator, Synthesis Core (Core Project B in Superfund Chemicals: Transport, Metabolism and Toxicity), $50,775 Year 1, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Principal Investigator, Superfund Chemicals: Transport, Metabolism and Toxicity (Conference Support), $40,000, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Co-Investigator, Mechanisms of hepatic tumor promotion by PCBs, H. Glauert, PI (Project #3 of Superfund Chemicals: Transport, Metabolism and Toxicity), $123,090 Year 1, Apr 2000 to Mar 2005.
  • National Institutes of Health (NIH): Co-Investigator, Effects of Lipd Mediators on Superfund Chemical-Induced Endothelial Cell Dysfunction (Supplement), B. Hennig, PI, $67,999, Apr 1999 to Mar 2000.
  • National Institutes of Health (NIH): Principal Investigator, Superfund Chemicals: Transport, Metabolism and Toxicity (Conference Support), $32,500, Apr 1998 to Mar 2001.
  • National Institutes of Health (NIH): Principal Investigator, Superfund Chemicals: Transport, Metabolism and Toxicity, $1,946,624, Apr 1997 to Mar 2000.
  • National Institutes of Health (NIH): Principal Investigator, Activation of PCBs to genotoxins in vivo (Project #1 in Superfund Chemicals: Transport, Metabolism and Toxicity), $476,043, Apr 1997 to Mar 2000.
  • National Institutes of Health (NIH): Co-Investigator, Superfund chemicals and endothelial cell dysfunction, B. Hennig, PI (Project #2 in Superfund Chemicals: Transport, Metabolism and Toxicity), $439,533, Apr 1997 to Mar 2000.
  • National Institutes of Health (NIH): Co-Investigator, Mechanisms of hepatic tumor promotion by PCBs, H. Glauert, PI (Project #3 of Superfund Chemicals: Transport, Metabolism and Toxicity), $311,762, Apr 1997 to Mar 2000.
  • Environmental Protection Agency (EPA): Principal Investigator, Cooperative agreement for risk assessment research related to halogenated hydrocarbons, $28,500, Apr 1994 to Sep 1995.
  • Centers for Disease Control and Prevention: Co-Investigator, Center for Agricultural Research, R. McKnight, PI, $25,490, Apr 1993 to Sep 1994.
  • National Institutes of Health (NIH): Co-Investigator, Diet and Carcinogenesis by Peroxisome Proliferators, H. Glauert, PI, $91,510, Apr 1991 to Mar 1994.
  • NIEHS: Program Director, Supplemental funding to Semi-volatile PCBs: Sources, exposures, toxicities for a two-day workshop, 2007 to 2007.
  • NIH: Principal Investigator, Semi-Volatile PCBs: Sources, Exposures, Toxicities, $12,130,718, 2006 to 2010.
  • NIEHS: Program Director, Semi-volatile PCBs: Sources, exposures, toxicities, 2006 to 2010.
  • Univeristy of Kentucky Research Foundation/NIH: Principal Investigator, Synthetic PCBs - UK SBRP Research Support Core, $95,920, 2005 to 2008.
  • Subcontract from the University of Kentucky: Superfund Basic Research Program, 2005 to 2008.
  • NIEHS: Principal Investigator, Distribution of PCB atropisomers, 2004 to 2009.
  • University of Kentucky/NIH: Principal Investigator, Super Fund Basic Research Program, $347,443, 2003 to 2006.
  • Environmental Protection Agency (EPA): Co-Investigator, Polyhalogenated diphenyl ethers - an emerging environmental threat?, G. Ludewig, PI, $334,996, 2001 to 2006.
  • NIEHS: Pilot Grant Program Director and Co-Director of the Toxicology and Oxidative Stress Research Core, Environmental Health Sciences Research Center, P Thorne, PI, $17,442,062, 1990 to 2007.

Publications

  • Dreiem A, Rykken S, Lehmler HJ, Robertson LW, Fonnum F (Oct 2009) Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells., Toxicology and applied pharmacology, 240 (2), 306-13 Abstract
  • Zhu Y, Kalen AL, Li L, Lehmler HJ, Robertson LW, Goswami PC, Spitz DR, Aykin-Burns N (Sep 2009) Polychlorinated biphenyl (PCB)-induced oxidative stress and cytotoxicity can be mitigated by antioxidants following exposure., Free radical biology & medicine Abstract
  • Liu Y, Smart JT, Song Y, Lehmler HJ, Robertson LW, Duffel MW (May 2009) Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status., Drug metabolism and disposition: the biological fate of chemicals, 37 (5), 1065-72 Abstract
  • Spencer WA, Lehmler HJ, Robertson LW, Gupta RC (May 2009) Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species., Free radical biology & medicine, 46 (10), 1346-52 Abstract
  • Suh YW, Buettner GR, Venkataraman S, Treimer SE, Robertson LW, Ludewig G (Apr 2009) UVA/B-induced formation of free radicals from decabromodiphenyl ether., Environmental science & technology, 43 (7), 2581-8 Abstract
  • Zhao HX, Adamcakova-Dodd A, Hu D, Hornbuckle KC, Just CL, Robertson LW, Thorne PS, Lehmler HJ (Apr 2009) Development of a synthetic PCB mixture resembling the average polychlorinated biphenyl profile in Chicago air., Environment international Abstract
  • Telu S, Parkin S, Robertson LW, Lehmler HJ (Mar 2009) Improved syntheses of non-dioxin-like polychlorinated biphenyls (PCBs) and some of their sulfur-containing metabolites., Environment international Abstract
  • Liu Y, Smart JT, Song Y, Lehmler HJ, Robertson LW, Duffel MW (Feb 2009) Structure-Activity Relationships for Hydroxylated Polychlorinated Biphenyls as Substrates and Inhibitors of Rat Sulfotransferases and Modification of these Relationships by Changes in Thiol Status., Drug metabolism and disposition: the biological fate of chemicals Abstract
  • Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W (Jan 2009) Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2., Chemical research in toxicology, 22 (1), 201-7 Abstract
  • Li X, Robertson LW, Lehmler HJ (2009) Electron ionization mass spectral fragmentation study of sulfation derivatives of polychlorinated biphenyls., Chemistry Central journal, 3, 5 Abstract
  • Klösener J, Peters TM, Adamcakova-Dodd A, Teesch LM, Thorne PS, Robertson LW, Luthe G (Jan 2009) Innovative application of fluoro tagging to trace airborne particulate and gas-phase polybrominated diphenyl ether exposures., Chemical research in toxicology, 22 (1), 179-86 Abstract
  • Wangpradit O, Mariappan SV, Teesch LM, Duffel MW, Norstrom K, Robertson LW, Luthe G (Dec 2008) Oxidation of 4-Chlorobiphenyl Metabolites to Electrophilic Species by Prostaglandin H Synthase., Chemical research in toxicology Abstract
  • Glauert HP, Tharappel JC, Banerjee S, Chan NL, Kania-Korwel I, Lehmler HJ, Lee EY, Robertson LW, Spear BT (Oct 2008) Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice., Toxicology and applied pharmacology, 232 (2), 302-8 Abstract
  • Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W (Oct 2008) Enantiomeric Specificity of (-)-2,2',3,3',6,6'-Hexachlorobiphenyl toward Ryanodine Receptor Types 1 and 2., Chemical research in toxicology Abstract
  • Kania-Korwel I, Xie W, Hornbuckle KC, Robertson LW, Lehmler HJ (Oct 2008) Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes., Archives of environmental contamination and toxicology, 55 (3), 510-7 Abstract
  • Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC (Jul 2008) Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells., Free radical biology & medicine, 45, 1094-1102 Abstract
  • Luthe G, Garcia Boy R, Jacobus J, Smith BJ, Rahaman A, Robertson LW, Ludewig G (May 2008) Xenobiotic geometry and media pH determine cytotoxicity through solubility., Chemical research in toxicology, 21 (5), 1017-27 Abstract
  • Ravoori S, Ayotte P, Srinivasan C, Pereg D, Robertson LW, Russell GK, Jeyabalan J, Gupta RC (2008) DNA damage associated with PCBs in the whole blood cells of Inuit, Environmental Toxicology and Pharmacology, 25 (2), 273-6
  • Luthe G, Jacobus JA, Robertson LW (2008) Receptor interactions by polybrominated diphenyl ethers versus polychlorinated biphenyls: A theoretical structure-activity assessment, Environmental Toxicology and Pharmacology, 25 (2), 202-10
  • Ludewig G, Lehmann L, Esch H, Robertson LW (2008) Metabolic activation of PCBs to carcinogens in vivo--A review, Environmental Toxicology and Pharmacology Special Issue "Focus on PCBs: Recent Advances in Environmental Distribution and Health Effects", 25 (2), 241-6
  • Jacobus JA, Flor S, Klingelhutz AJ, Robertson LW, Ludewig G (2008) 2-(4-chlorophenyl)-1,4-benzoquinone increases the frequency of micronuclei and shortens telomeres, Environmental Toxicology and Pharmacology Special Issue "Focus on PCBs: Recent Advances in Environmental Distribution and Health Effects", 25 (2), 267-72
  • Robertson LW, Sulkowski W, Hennig B (2008) Special Issue of Environmental Toxicology and Pharmacology, 2 Edition, Vol. 25, Focus on PCBs: Recent advances in environmental distribution and health effects, Guest Editors: L Robertson, W Sulkowski, B Hennig
  • Klösener J, Swenson DC, Robertson LW, Luthe G (Feb 2008) Effects of fluoro substitution on 4-bromodiphenyl ether (PBDE 3)., Acta crystallographica. Section B, Structural science, 64 (Pt 1), 108-19 Abstract
  • Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler HJ (2008) Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice, Food Chem Toxicol, 46 (2), 637-44
  • Kania-Korwel I, Hornbuckle K, Robertson L, Lehmler H-J (2008) Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice, Environ Toxicol Chem, 27 (2), 299-305
  • Glauert HP, Tharappel JC, Lu Z, Stemm D, Banerjee S, Chan LS, Lee EY, Lehmler HJ, Robertson LW, Spear BT (2008) Role of Oxidative Stress in the Promoting Activities of PCBs., Environmental toxicology and pharmacology, 25 (2), 247-250 Abstract
  • Song Y, Buettner G, Parkin S, Wagner B, Robertson LW, Lehmler H-J (2008) Chlorination Increases the Persistence of Semiquinone Free Radicals Derived from Polychlorinated Biphenyl Hydroquinones and Quinones, Journal of Organic Chemistry, 73, 8296-304
  • Li X, Parkin S, Robertson LW, Lehmler H-J (2008) 4'-Chlorobiphenyl-4-yl 2,2,2-trichloroethyl sulfate, Acta Cryst, E64, o2464
  • Stemm DN, Tharappel JC, Lehmler H-J, Srinivasan C, Morris JS, Spate VL, Robertson LW, Spear BT, Glauert HP (2008) Effect of Dietary Selenium on the Promotion of Hepatocarcinogenesis by 3,3',4,4'-Tetrachlorobiphenyl and 2,2',4,4',5,5'-Hexachlorobiphenyl, Exp Biol Med, 233, 366-76
  • Sacco JC, Lehmler H-J, Robertson LW, James MO (2008) Glucuronidation of polychlorinated biphenylols and UDPGA concentration in channel catfish liver and intestine, Drug Metabolism and Disposition, 36, 623-30
  • Telu S, Parkin S, Robertson LW (2008) 1,3,5-Trichloro-2-methoxybenzene. Acta Crystallographica Section E Structure Reports Online, Acta Cryst, E64, o424
  • Tharappel JC, Lehmler H-J, Srinivasan C, Robertson LR, Spear BT, Glauert HP (2008) Effect of Antioxidant Phytochemicals on the Hepatic Tumor Promoting Activity of 3,3',4,4'-Tetrachlorobiphenyl (PCB-77), Food and Chemical Toxicology, 46, 3467-74
  • Bunaciu RP, Tharappel JC, Lehmler HJ, Kania-Korwel I, Robertson LW, Srinivasan C, Spear BT, Glauert HP (Oct 2007) The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats., Toxicology, 239 (3), 147-55 Abstract
  • Zettner M, Flor S, Ludewig G, Wagner J, Robertson LW, Lehmann L (2007) Quinoid metabolites of 4-monochlorobiphenyl (PCB3) induce gene mutations in cultured Chinese hamster V79 cells, Toxicological Sciences, 100, 88-98
  • Robertson LW, Berberian I, Borges T, Chen L-C, Chow CK, Glauert HP, Filser JG, Thomas H (2007) Suppression of peroxisomal enzyme activities and cytochrome P-4504A isozyme expression by congeneric polybrominated and polychlorinated biphenyls, PPAR Research, Article 15481, 5 pages
  • Sadeghi-aliabadi H, Chan K, Lehmler H-J, Robertson LW, O'Brien PJ (2007) Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes, Chemico-Biological Interactions, 167, 184-92
  • Luthe G, Swenson DC, Robertson LW (2007) Influence of fluoro-substitution on the planarity of 4-chlorobiphenyl (PCB 3), Acta Cryst, B63, 319-27
  • Lehmann L, Esch HL, Kirby PA, Robertson LW, Ludewig G (2007) 4-Monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats, Carcinogenesis, 28, 471-8
  • Kania-Korwel I, Shaikh NS, Hornbuckle KC, Robertson LW, Lehmler HJ (2007) Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration, Chirality, 19 (1), 56-66
  • Ludewig G, Esch H, Robertson LW (2007) Polyhalogenierte Bi- und Terphenyle, In: Dunkelberg H, Gebel T, Hartwig A (Editors) Handbuch der Lebensmitteltoxikologie, Chapter 20 Edition, Wiley-VCH Weinheim, 1031-1094 pages (bookchapter)
  • Liu Y, Apak TI, Lehmler HJ, Robertson LW, Duffel MW (2006) Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1, Chem Res Toxicol, 19 (11), 1420-5
  • Bender RP, Lehmler HJ, Robertson LW, Ludewig G, Osheroff N (2006) Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: Altering enzyme function by blocking the N-Terminal Protein Gate, Biochemistry, 45 (33), 10140-52
  • Kunz S, Schwarz M, Schilling O, Päpke O, Lehmler H-J, Robertson LW, Schrenk D, Schmitz H-J (2006) Tumor promoting potency of PCBs 28 and 101 in rat liver, Toxicol Lett, 164, 133-43
  • Vyas SM, Pakin S, Robertson LW, Lehmler H-J (2006) 2,5-Dichloro-4'-methoxybiphenyl, Acta Cryst E, 62, o4162-6
  • Ptak A, Ludewig G, Kapiszewska M, Magnowska Z, Lehmler H-J, Robertson LW, Gregoraszczuk EL (2006) Induction of cytochromes P-450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary, Toxicol Lett, 166, 200-11
  • Strathmann J, Schwarz M, Tharappel JC, Glauert HP, Spear BT, Robertson LW, Appel KE, Buchmann A (2006) PCB 153, a non-dioxin-like tumor promoter, selects for ß-Catenin (Catnb) mutated mouse liver tumors, Toxicological Sciences, 93, 34-40
  • Vyas SM, Parkin S, Robertson LW, Lehmler H-J (2006) 4 -Chloro-2',3'-dimethoxybiphenyl, Acta Crystallographica, E (E62), o3639-o3640
  • Kania-Korwell I, Garrison AW, Avants JK, Hornbuckle KC, Robertson LW, Sulkowski WW, Lehmler H-J (2006) Distribution of Chiral PCBs in Selected Tissues in the Laboratory Rat, Environmental Science & Technology, 40, 3704-10
  • Wang L-Q (2006) Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate, Chem.-Biol. Interactions, 159, 235-46
  • Ptak A, Ludewig G, Robertson LW, Lehmler H-J, Gregoraszczuk EL (2006) In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity, Toxicology Letters, 164, 113-22
  • Kunz S, Schmitz A, Buchmann M, Schwarz B, Schilling O, Päpke O, Lehmler H-J, Robertson LW, Schrenk D (2006) Tumor promoting potency of PCBs 28 and 101 in rat liver, Toxicology Letters, 164, 133-43
  • Luthe G, Leonards PEG, Reijerink GS, Liu H, Johansen JE, Robertson LW (2006) Monofluorinated analogues of polybrominated diphenyl ethers (F-PBDEs) as analytical standards: Synthesis, NMR and GC-MS characterization and molecular orbital studies, Environ Sci Technol, 40, 3023-9
  • Wang L-Q, Lehmler H-J, Robertson LW, James MO (2006) Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate, Chem-Biol Interactions, 159, 235-46
  • Wang LQ, Lehmler HJ, Robertson LW, Falany CN, James MO, In Vitro Inhibition of Human Hepatic and CDNA-expressed Sulfotransferase Activity With 3-hydroxybenzo[a]pyrene By Polychlorobiphenylols., Environmental Health Perspectives, 113(6), 680-7, Jun 2005 Abstract
  • Kania-Korwel I, Hornbuckle KC, Peck A, Ludewig G, Robertson, LW, Sulkowski WW, Espandiari P, Gairola CG, Lehmler HJ, Congener-specific Tissue Distribution of Aroclor 1254 and a Highly Chlorinated Environmental PCB Mixture in Rats, Environmental Science & Technology, 39(10), 3513-20, 15 May 2005
  • Ritchie JM, Vial SL, Fuortes LJ, Robertson LW, Guo H, Reedy VE, Smith EM, Comparison of Proposed Frameworks for Grouping Polychlorinated Biphenyl Congener Data Applied to a Case–control Pilot Study of Prostate Cancer, Environmental Research, 98(1), 104-113, May 2005
  • Ritchie JM, Vial SL, Fuortes LJ, Robertson LW, Guo H, Reedy VE, Smith EM (May 2005) Comparison of proposed frameworks for grouping polychlorinated biphenyl congener data applied to a case-control pilot study of prostate cancer., Environmental Research, 98 (1), 104-13 Abstract
  • Lehmler HJ, Robertson LW, Garrison AW, Kodavanti PR (Apr 2005) Effects of PCB 84 enantiomers on [3H]-phorbol ester binding in rat cerebellar granule cells and 45Ca2+-uptake in rat cerebellum., 156 (3), 391-400 Abstract
  • Glauert HP, Lu Z, Kumar A, Bunaciu RP, Patel S, Tharappel JC, Stemm DN, Lehmler HJ, Lee EY, Robertson LW, Spear BT (Feb 2005) Dietary vitamin E does not inhibit the promotion of liver carcinogenesis by polychlorinated biphenyls in rats., The Journal of Nutrition, 135 (2), 283-6 Abstract
  • Hennig B, Reiterer G,Toborek M, Matveev SV, Daugherty A, Smart E, Robertson LW, Dietary Fat Interacts With PCBs to Induce Changes in Lipid Metabolism in Mice Deficient in Low-density Lipoprotein Receptor, Environmental Health Perspectives, 113(1), 83-7, Jan 2005
  • Lehmler H-L, Robertson LW, Garrison AW, Kodavanti PRS, Effects of PCB 84 Enantiomers on [3H] Phorbol Ester Binding in Rat Cerebellar Granule Cells and 45Ca2+-uptake in Rat Cerebellum, Toxicology Lett, 156, 391-400, 2005
  • Ptak A,Ludewig G,Lehmler H-J, Wójtowicz A, Robertson LW, Ewa L, Comparison of the Actions of 4-chlorobiphenyl and Its Hydroxylated Metabolites on Estradiol Secretion By Ovarian Follicles in Primary Cells in Culture, Reproductive Toxicology, 20, 57-64, 2005
  • Hennig B, Toborek M, Ramadass P, Ludewig G, Robertson LW, Polychlorinated Biphenyls, Oxidative Stress and Diet, Reviews in Food and Nutrition Toxicity, 3, 93-128, 2005
  • Espandiari P; Robertson LW, Srinivasan C, Comparison of Different Initiation Protocols in the Resistant Hepatocyte Model, Toxicology, 206, 373-81, 2005
  • Glauert HP, Lu Z, Kumar A, Bunaciu RP, Patel S, Tharappel JC, Stemm DN, Lehmler H-J, Lee EY, Robertson LW, Spear BT, Dietary Vitamin E Does Not Inhibit the Promotion of Liver Carcinogenesis By Polychlorinated Biphenyls in Rat, Journal of Nutrition, 135, 283-6, 2005
  • Stemm DN; Robertson LW, Tharappel JC, Spear BT, Lehmler h-J, Glauert HP, Effects of Dietary Selenium on the Hepatic Tumor Promoting Activities of PCBs, Toxicol Sci, 84(1-S), 303, 2005
  • Tharappel JC, Stemm DN, Bunaciu RP, Robertson LW, Lehmler H-J, Spear BT, Glauert HP, Effects of Selected Dietary Antioxidant Phytochemicals on the Hepatic Tumor Promoting Activity of PCB – 77., Toxicol Sci, 84(1-S), 303, 2005
  • Hansen L, Machala M, Fischer L, James M, Hennig B, Glauert H, Narbonne J-F, Van Bree L, Scholtz T, Grevatt P, Suk W, Holoubek I, Robertson L (2005) Research needs identified at the Second PCB Workshop in Brno, Czech Republic, May 7-11, 2002, Toxicological & Environmental Chemistry, 87 (3), 261-5
  • Espandiari P, Robertson LW, Srinivasan C, Glauert HP (Jan 2005) Comparison of different initiation protocols in the resistant hepatocyte model., 206 (3), 373-81 Abstract
  • Hennig B, Reiterer G, Toborek M, Matveev SV, Daugherty A, Smart E, Robertson LW (2005) Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in Low-Density Lipoprotein Receptor, Environ Health Perspect, 113, 83-7
  • Kania-Korwel I, Hornbuckle KC, Peck A, Ludewig G, Robertson LW, Sulkowski W, Espandiari P, Gairola CG, Lehmler H-J (2005) ongener specific tissue distribution of Aroclor 1254 and a highly chlorinated environmental PCB mixture in rats, Environmental Science & Technology, 39, 3513-20
  • Lehmler H-J, Robertson LW, Parkin S (2005) 2,2',3,3',6-Pentachlorobiphenyl (PCB 84)," Acta Crystallographica Section, E61, o3025-6
  • Kodavanti PRS, Ward TR, Ludewig G, Robertson LW, Birnbaum LS (2005) Polybrominated Diphenyl Ether (PBDE) Effects in Rat Neuronal Cultures: 14C-PBDE Accumulation, Biological Effects, and Structure-Activity Relationships, Toxicological Sciences, 88 (181-92)
  • Kania-Korwel I, Parkin S, Robertson LW, Lehmler HJ, 2,4,5-Trichlorobiphenyl, Acta Crystallographica, Section e (Structure Reports Online), 60(Part 9), O1652-3, September 2004
  • Lu Z, Lee EY, Robertson LW, Glauert HP, Spear BT, Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) on Hepatocyte Proliferation and Apoptosis in Mice Deficient in the P50 Subunit of The Transcription Factor NF-kappaB., Toxicological Sciences : An Official Journal of the Society of Toxicology, 81(1), 35-42, Sep 2004 Abstract
  • Gauger KJ, Kato Y, Haraguchi K, Lehmler HJ, Robertson LW, Bansal R, Zoeller RT, Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors, Environmental Health Perspectives, 112(5), 516-23, 2004
  • Kania-Korwel I, Parkin S, Robertson LW, Lehmler H-J, Synthesis of polychlorinated biphenyls and their metabolites with a modified Suzuki-coupling, Chemosphere, 56, 735-44, 2004
  • Glauert H, Tharappel J, Stemm D, Lehmler H, Robertson L, Spear B, Effect of dietary antioxidants on the promotion of hepatocarcinogenesis by PCBs, Organohalogen Compounds, 66, 3148-52, 2004
  • Ptak A, Ludewig G, Lehmler H-J, Robertson LW, Gregoraszczuk EL, Effect of PCB3 and its hydroxylated metabolites on estradiol secretion, cell viability, and caspase-3 activity in porcine small follicles, Organohalogen Compounds, 66, 2973-8, 2004
  • Fonnum F, Dreiem A, Lehmler H-J, Mariussen E, Rykken S, L Robertson, The effect of hydroxylated PCBs on DCF-fluorescence and cell death in cultured rat cerebellar granule cells, Organohalogen Compounds, 66, 3120-3, 2004
  • Kunz S, Schmitz H-J, Buchmann A, Schwarz M, Schilling B, Päpke O, Robertson LW, Lehmler H-J, Schrenk D, Analysis of the tumor-promoting potency of 2,4,4’-trichlorobiphenyl and 2,2’,4,5,5’-pentachlorobiphenyl in rat liver, Organohalogen Compounds, 66, 3603-9, 2004
  • Kania-Korwel I, Hornbuckle KC, Peck A, Sulkowski WW, Ludewig G, Robertson LW, Lehmler H-J, Comparison of PCB congener profiles in tissues of PCB-treated rats, Organohalogen Compounds, 66, 2915-22, 2004
  • Lehmler H-J, Kania-Korwel I, Avants JK, Hornbuckle KC, Sulkowski WW, Robertson LW, Garrison WA, Distribution of chiral PCBs in selected tissues in the laboratory rat, Organohalogen Compounds, 66, 452-9, 2004
  • Kodavanti PR, Ward T, Burka T, Ludewig G, Robertson L, Birnbaum L, Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effect, and structure-activity relationships, Organohalogen Compounds, 66, 3133-8, 2004
  • Hennig B, Reiterer G, Toborek M, Matveev SV, Daugherty A, Smart E, Robertson LW, Dietary fat interacts with PCBs to induce changes in lipid metabolism in LDL receptor deficient mice, Organohalogen Compountes, 66, 2903-6, 2004
  • Kania-Korwel I, Ludewig G, Robertson LW, Hornbuckle KC, Peck A, Espandiari P, Gairola CG, Sulkowski WW, Lehmler H-J, Biochemical effects of an environmental Chlorofen mixture in comparison with Aroclor 1254 in rats, Organohalogen Compounds, 66, 2985-92, 2004
  • Ramadass P, Meerarani P, Toborek M, Robertson LW, Hennig B, Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells, Toxicological Sciences : an Official Journal of the Society of Toxicology., 76(1), 212-9, November 2003 Abstract
  • Kania-Korwel I, Robertson LW, Lehmler H-J, Parkin S, 2,4,6-Trichloro-iodobenzene, Acta Cryst, E59(Part 11), o1770-1, November 2003
  • Choi W, Eum SY, Lee YW, Hennig B, Robertson LW, Toborek M, PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis, Toxicological Sciences : an Official Journal of the Society of Toxicology, 75(1), 47-56, September 2003
  • Lee YW, Park HJ, Son KW, Hennig B, Robertson LW, Toborek M, 2,2',4,6,6'-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB, Toxicology and Applied Pharmacology, 189(1), 1-10, May 2003 Abstract
  • Tampal NM, Robertson LW, Srinivasan C, Ludewig G, Polychlorinated biphenyls are not substrates for the multidrug resistance transporter-1, Toxicology and Applied Pharmacology, 187(3), 168-77, March 2003 Abstract
  • Arif JM, Lehmler H-J, Robertson LW, Gupta RC, Interaction of benzoquinone- and hydroquinon-derivatives of lower chlorinated biphenyls with DNA and nuceotides in vitro, Chemico-Biological Interactions, 142, 307-316, 2003
  • Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW, Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model, Toxicology and Applied Pharmacology, 186(1), 55-62, January 2003 Abstract
  • Tampal N, Myers S, Robertson LW, Binding of polychlorinated biphenyls / metabolites to hemoglobin, Toxicology Letters, 142, 53-60, 2003
  • Hennig B, Toborek M, Robertson LW, Nutrition and proinflammatory mechanisms of PCB toxicity in the vascular endothelium, Fresenius Environmental Bulletin, 12, 240-4, 2003
  • Lehmler H-J, Price DJ, Garrison AW, Birge WJ, Robertson LW, Distribution of PCB 84 enantiomers in C57Bl/6 mice, Fresenius Environmental Bulletin, 12, 254-60, 2003
  • Kania-Korwel I, Lehmler HJ, Robertson LW, 2,4,5-trichloro-1-iodobenzene, Acta Crystallographica, Section e (Structure(59 Part 7), 01048-9, 2003
  • Sulkowski WW, Kania-Korwel I, Robertson LW, Polychlorinated biphenyls production in Poland, Fresenius Environmental Bulletin, 12, 152-7, 2003
  • Wlodarczyk-Makula M, Sulkowski WW, Popenda A, Robertson LW, The influence of sewage and sludge treatment processes on concentrations of polycyclic aromatic hydrocarbons, Fresenius Environmental Bulletin, 12, 338-42, 2003
  • Sulkowski WW, Kania-Korwel I, Robertson LW, Szafran B, Lulek J, Post-production polychlorinated biphenyls levels in soil, Fresenius Environmental Bulletin, 12, 158-64, 2003
  • Lu Z, Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP, Effect of a Single Dose of Polychlorinated Biphenyls (PCBs) on Hepatic Cell Proliferation and the DNA Binding Activity of NF-kB and AP-1 in Rats, Molec. Carcinogenesis, 37(4), 171-80, 2003
  • Machala M, Bláha L, Lehmler H-J, Plísková M, Májková Z, Kapplová P, Sovadinová I, Vondrácek J, Malmberg T, Robertson LW, Toxicity of Hydroxylated and Quinoid PCB Metabolites: Inhibition of Gap Junctional Intercellular Communication and Activation of Aryl Hydrocarbon and Estrogen Receptors in Hepatic and Mammary Cells, Chem Res Toxicol, (in press), 2003
  • Tampal NM, Robertson LW, Srinivasan C, Ludewig G, Polychlorinated Biphenyls are not Substrates for the Multidrug Resistance Transporter-1, MDR1, Toxicology and Applied Pharmacology, 142(1-2), 53-60, 2003
  • Sulkowski WW, Kania-Korwel I, Robertson LW, Szafran B, Lulek J, Post-production polychlorinated biphenyls levels in soil, Fresenius Environmental Bulletin, 12, 158-64, 2003
  • Tampal N, Lehmler HJ, Espandiari P, Malmberg T, Robertson LW, Glucuronidation of hydroxylated polychlorinated biphenyls (PCBs), Chemical Research in Toxicology, 15(10), 1259-66, October 2002 Abstract
  • Fadhel Z, Lu Z, Robertson LW, Glauert HP, Effect of 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl on the induction of hepatic lipid peroxidation and cytochrome P-450 associated enzyme activities in rats, Toxicology, 175(1-3), 15-25, June 2002 Abstract
  • Hennig B, Meerarani P, Slim R, Toborek M, Daugherty A, Silverstone AE, Robertson LW, Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence, Toxicology and Applied Pharmacology, 181(3), 174-83, June 2002 Abstract
  • Srinivasan A, Robertson LW, Ludewig G, Sulfhydryl binding and topoisomerase inhibition by PCB metabolites, Chemical Research in Toxicology, 15(4), 497-505, April 2002 Abstract
  • Hennig B, Hammock BD, Slim R, Toborek M, Saraswathi V, Robertson LW, PCB-induced oxidative stress in endothelial cells: modulation by nutrients, International Journal of Hygiene and Environmental Health, 205(1-2), 95-102, March 2002 Abstract
  • Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP, Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls, Toxicology and Applied Pharmacology, 179(3), 172-84, March 2002 Abstract
  • Pereg D, Robertson LW, Gupta RC, DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites, Chemico-biological Interactions, 139(2), 129-44, February 2002 Abstract
  • Lehmler HJ, Robertson LW, Parkin S, Brock CP, Z' = 4 structure without obvious pseudosymmetry: implications for the formation of solid-state compounds, Acta crystallographica, Section B: Structural Science, 58(Pt 1), 140-7, February 2002 Abstract
  • Lehmler HJ, Parkin S, Robertson LW, The three-dimensional structure of 3, 3', 5'-trichloro-4-methoxybiphenyl, a 'coplanar' polychlorinated biphenyl (PCB) derivative, Chemosphere, 46(3), 485-8, January 2002 Abstract
  • Lehmler H-J, Robertson LW, Parkin S, 2-(3,5-Dichlorophenry)-1, 4-benzoquinone, Acta Crystallographica Section E, E58, o366-7, 2002
  • Lehmler HJ, Robertson LW, Synthesis of hydroxylated PCB metabolites with the Suzuki-coupling, Chemosphere, 45(8), 1119-27, December 2001 Abstract
  • Lehmler HJ, Robertson LW, Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-coupling, Chemosphere, 45(2), 137-43, October 2001 Abstract
  • Pereg D, Tampal N, Espandiari P, Robertson LW, Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice, Chemico-biological Interactions, 137(3), 243-58, September 2001 Abstract
  • Twaroski TP, O'Brien ML, Robertson LW, Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress, Biochemical Pharmacology, 62(3), 273-81, August 2001 Abstract
  • Oakley GG, Roe AL, Blouin RA, Twaroski TP, Ganguly TC, Vore M, Lehmler HJ, Robertson LW, 2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity, Molecular Carcinogenesis, 30(4), 199-208, April 2001 Abstract
  • Srinivasan A, Lehmler HJ, Robertson LW, Ludewig G, Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites, Toxicological Sciences : an Official Journal of the Society of Toxicology, 60(1), 92-102, March 2001 Abstract
  • Twaroski TP, O'Brien ML, Larmonier N, Glauert HP, Robertson LW, Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver, Toxicology and Applied Pharmacology, 171(2), 85-93, March 2001 Abstract
  • Slim R, Hammock BD, Toborek M, Robertson LW, Newman JW, Morisseau CH, Watkins BA, Saraswathi V, Hennig B, The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells, Toxicology and Applied Pharmacology, 171(3), 184-93, March 2001 Abstract
  • Lehmler H-J, Robertson LW, Parkin S, 4-Chloro-3',4'-dihydroxybiphenyl, Acta Crystallographica, Section E, 57, o590-o591, 2001
  • Lehmler H-J, Parkin S, Robertson LW, 2,3,4-Trichlorobiphenyl, Acta Crystallographica, Section E, 57, o111-o112, 2001
  • Ludewig G, Srinivasan A, Robertson LW, Mechanisms of toxicity of PCB metabolites: generation of reactive oxygen species and glutathione depletion, Central European Journal of Public Health, 8 Suppl, 15-7, July 2000 Abstract
  • Slim R, Toborek M, Robertson LW, Lehmler HJ, Hennig B, Cellular glutathione status modulates polychlorinated biphenyl-induced stress response and apoptosis in vascular endothelial cells, Toxicology and Applied Pharmacology, 166(1), 36-42, July 2000 Abstract
  • Glauert HP, Tharappel JC, Lee EY, Robertson LW, Spear BT, Effect of PCBs on the activation of the transcription factors AP-1 and NF-kappa B, Central European Journal of Public Health, 8 Suppl, 17-8, July 2000 Abstract
  • Hennig B, Slim R, Toborek M, Malecki A, Robertson LW, Effects of lipids and antioxidants on PCB-mediated dysfunction of vascular endothelial cells (EC), Central European Journal of Public Health, 8 Suppl, 18-9, July 2000 Abstract
  • Robertson LW, Espandiari P, Lehmler HJ, Pereg D, Srinivasan A, Tampal N, Twaroski T, Ludewig G, Glauert HP, Arif J, Gupta R, Metabolism and activation of polychlorinated biphenyls (PCBs), Central European Journal of Public Health, 8 Suppl, 14-5, July 2000 Abstract
  • McLean MR, Twaroski TP, Robertson LW, Redox cycling of 2-(x'-mono, -di, -trichlorophenyl)- 1, 4-benzoquinones, oxidation products of polychlorinated biphenyls, Archives of Biochemistry and Biophysics, 376(2), 449-55, April 2000 Abstract
  • Slim R, Toborek M, Robertson LW, Hennig B, Antioxidant protection against PCB-mediated endothelial cell activation, Toxicological Sciences : an Official Journal of the Society of Toxicology, 52(2), 232-9, December 1999 Abstract
  • Espandiari P, Glauert HP, Lee EY, Robertson LW, Promoting activity of the herbicide dicamba (2-methoxy-3, 6-dichlorobenzoic acid) in two stage hepatocarcinogenesis, International Journal of Oncology, 14(1), 79-84, Jan 1999 Abstract
  • Hennig B, Slim R, Toborek M, Robertson LW, Linoleic acid amplifies polychlorinated biphenyl-mediated dysfunction of endothelial cells, Journal of Biochemical and Molecular Toxicology, 13(2), 83-91, 1999 Abstract
  • Espandiari P, Ludewig G, Glauert HP, Robertson LW, Activation of hepatic NF-kappaB by the herbicide Dicamba (2-methoxy-3,6-dichlorobenzoic acid) in female and male rats, Journal of Biochemical and Molecular Toxicology, 12(6), 339-44, 1998 Abstract
  • Oakley GG, Devanaboyina U, Robertson LW, Gupta RC, Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer, Chemical Research in Toxicology, 9(8), 1285-92, December 1996 Abstract
  • Amaro AR, Oakley GG, Bauer U, Spielmann HP, Robertson LW, Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase, Chemical Research in Toxicology, 9(3), 623-9, 1996 Abstract
  • Oakley GG, Robertson LW, Gupta RC, Analysis of polychlorinated biphenyl-DNA adducts by 32P-postlabeling, Carcinogenesis, 17(1), 109-14, January 1996 Abstract
  • McLean MR, Robertson LW, Gupta RC, Detection of PCB adducts by the 32P-postlabeling technique, Chemical Research in Toxicology, 9(1), 165-71, 1996 Abstract
  • McLean MR, Bauer U, Amaro AR, Robertson LW, Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl, Chemical Research in Toxicology, 9(1), 158-64, 1996 Abstract
  • Toborek M, Barger SW, Mattson MP, Espandiari P, Robertson LW, Hennig B, Exposure to polychlorinated biphenyls causes endothelial cell dysfunction, Journal of Biochemical Toxicology, 10(4), 219-26, August 1995 Abstract
  • Espandiari P, Thomas VA, Glauert HP, O'Brien M, Noonan D, Robertson LW, The herbicide dicamba (2-methoxy-3,6-dichlorobenzoic acid) is a peroxisome proliferator in rats, Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology., 26(1), 85-90, June 1995 Abstract
  • Berberian I, Chen LC, Robinson FR, Glauert HP, Chow CK, Robertson LW, Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl in rats initiated with diethylnitrosamin, Carcinogenesis, 16(2), 393-8, February 1995 Abstract
  • Bauer U, Amaro AR, Robertson LW, A new strategy for the synthesis of polychlorinated biphenyl metabolites, Chemical Research in Toxicology, 8(1), 92-5, 1995 Abstract
  • Wilson MW, Lay LT, Chow CK, Tai HH, Robertson LW, Glauert HP, Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid, Archives of Toxicology, 69(7), 491-7, 1995 Abstract
  • Huang CY, Wilson MW, Lay LT, Chow CK, Robertson LW, Glauert HP, Increased 8-hydroxydeoxyguanosine in hepatic DNA of rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid, Cancer Letters, 87(2), 223-8, December 1994 Abstract
  • Chen H, Huang CY, Wilson MW, Lay LT, Robertson LW, Chow CK, Glauert HP, Effect of the peroxisome proliferators ciprofibrate and perfluorodecanoic acid on hepatic cell proliferation and toxicity in Sprague-Dawley rats, Carcinogenesis, 15(12), 2847-50, December 1994 Abstract
  • Bani MH, Narbonne JF, Fukuhara M, Ushio F, Robertson LW, Differential modulation of hepatic cytochrome P-450 enzymes in rat and Syrian hamster by 4'-trifluoromethyl-2,3,4,5-tetrachlorobiphenyl, Journal of Biochemical Toxicology, 9(5), 241-8, October 1994 Abstract
  • Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA, Expression of the CYP3A and CYP2C11 enzymes in a nutritionally obese rodent model: response to phenobarbital treatment, International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity., 18(6), 369-74, June 1994 Abstract
  • Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA, Cytochrome P450 2B enzyme induction defect after 2,2',4,4',5,5'-hexachlorobiphenyl treatment in the fa/fa Zucker rat, Journal of Pharmacology and Experimental Therapeutics, 268(3), 1565-70, March 1994 Abstract
  • Chen L-C, Berberian I, Glauert HP, Robertson LW, Chow CK, Altered tissue levels of Vitamin A by selected polycyclic aromatic hydrocarbons (PAHs), Polycyclic Aromatic Compounds, 4, 173-182, 1994
  • Tuntaterdtum S, Chaudhary IP, Cibull M, Robertson LW, Blouin RA, Acetaminophen hepatotoxicity: influence of phenobarbital and beta-naphthoflavone treatment in obese and lean Zucker rats, Toxicology and Applied Pharmacology, 123(2), 219-25, December 1993 Abstract
  • Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A, Blouin RA, Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment, Archives of Biochemistry and Biophysics, 307(2), 386-90, December 1993 Abstract
  • Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA, Effect of nutritional obesity on the induction of CYP2B enzymes following phenobarbital treatment, Drug Metabolism and Disposition: the Biological Fate of Chemicals, 21(5), 782-7, 1993 Abstract
  • Borges T, Peterson RE, Pitot HC, Robertson LW, Glauert HP, Effect of the peroxisome proliferator perfluorodecanoic acid on the promotion of two-stage hepatocarcinogenesis in rats, Cancer Letters, 72(1-2), 111-20, August 1993 Abstract
  • Chaudhary IP, Tuntaterdtum S, McNamara PJ, Robertson LW, Blouin RA, Effect of genetic obesity and phenobarbital treatment on the hepatic conjugation pathways, Journal of Pharmacology and Experimental Therapeutics, 265(3), 1333-8, June 1993 Abstract
  • Blouin RA, Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A, Cytochrome P450 2B enzyme (CYP2B) induction defect following phenobarbital treatment in the fa/fa Zucker rat: molecular characterization, Archives of Biochemistry and Biophysics, 303(2), 313-20, June 1993 Abstract
  • Borges T, Glauert HP, Robertson LW, Perfluorodecanoic acid noncompetitively inhibits the peroxisomal enzymes enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase, Toxicology and Applied Pharmacology, 118(1), 8-15, January 1993 Abstract
  • Michel XR, Suteau P, Robertson LW, Narbonne J-F, Effects of benzo(a)pyrene, 3,3',3,3'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl on the xenobiotic-metabolizing enzymes in the mussel (Mytilus galloprovincialis), Aquatic Toxicology, 27, 335-344, 1993
  • Nishihara Y, Iwata M, Ikawa K, Puttmann M, Robertson LW, Miyahara M, Terada H, Utsumi K, The influence of chloro-substituent sites of hexachlorobiphenyl on the respiration of rat liver mitochondria, Chemical and Pharmaceutical Bulletin, 40(10), 2769-74, October 1992 Abstract
  • Pelissier MA, Siess MH, Lhuissier M, Grolier P, Suschetet M, Narbonne JF, Albrecht R, Robertson LW, Effect of prototypic polychlorinated biphenyls on hepatic and renal vitamin contents and on drug-metabolizing enzymes in rats fed diets containing low or high levels of retinyl palmitate, Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association., 30(8), 723-9, August 1992 Abstract
  • Chen LC, Berberian I, Koch B, Mercier M, Azais-Braesco V, Glauert HP, Chow CK, Robertson LW, Polychlorinated and polybrominated biphenyl congeners and retinoid levels in rat tissues: structure-activity relationships, Toxicology and Applied Pharmacology, 114(1), 47-55, May 1992 Abstract
  • Glatt H, Anklam E, Robertson LW, Biphenyl and fluorinated derivatives: liver enzyme-mediated mutagenicity detected in Salmonella typhimurium and Chinese hamster V79 cells, Mutation Research, 281(3), 151-6, March 1992 Abstract
  • Glauert HP, Srinivasan S, Tatum VL, Chen LC, Saxon DM, Lay LT, Borges T, Baker M, Chen LH, Robertson LW, et al., Effects of the peroxisome proliferators ciprofibrate and perfluorodecanoic acid on hepatic cellular antioxidants and lipid peroxidation in rats, Biochemical Pharmacology, 43(6), 1353-9, March 1992 Abstract
  • Borges T, Robertson LW, Peterson RE, Glauert HP, Dose-related effects of perfluorodecanoic acid on growth, feed intake and hepatic peroxisomal beta-oxidation, Archives of Toxicology, 66(1), 18-22, 1992 Abstract
  • Buchmann A, Ziegler S, Wolf A, Robertson LW, Durham SK, Schwarz M, Effects of polychlorinated biphenyls in rat liver: correlation between primary subcellular effects and promoting activity, Toxicology and Applied Pharmacology, 111(3), 454-68, December 1991 Abstract
  • Shedlofsky SI, Hoglen NC, Rodman LE, Honchel R, Robinson FR, Swim AT, McClain CJ, Robertson LW, 3,3',4,4'-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor, Hepatology (baltimore, Md.), 14(6), 1201-8, December 1991 Abstract
  • Rodman LE, Shedlofsky SI, Mannschreck A, Puttmann M, Swim AT, Robertson LW, Differential potency of atropisomers of polychlorinated biphenyls on cytochrome P450 induction and uroporphyrin accumulation in the chick embryo hepatocyte culture, Biochemical Pharmacology, 41(6-7), 915-22, March 1991 Abstract
  • Arand M, Coughtrie MW, Burchell B, Oesch F, Robertson LW, Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid, Chemico-biological Interactions, 77(1), 97-105, 1991 Abstract
  • Robertson LW, Silberhorn EM, Glauert HP, Scharz M, Buchmann A, Do structure-activity relationships for the acute toxicity of PCBs and PBBs also apply for indicution of hepatocellular carcinoma?, Environmental Toxicology and Chemistry, 10, 715-726, 1991
  • Narbonne JF, Grolier P, Albrecht R, Azais V, Oesch F, Robertson LW, A time course investigation of vitamin A level and lipid composition of the liver endoplasmic reticulum in rats following treatment with congeneric polychlorobiphenyls, Toxicology, 60(3), 253-61, March 1990 Abstract
  • Chen LC, Borges T, Glauert HP, Knight SA, Sunde RA, Schramm H, Oesch F, Chow CK, Robertson LW, Modulation of selenium-dependent glutathione peroxidase by perfluorodecanoic acid in rats: effect of dietary selenium, Journal of Nutrition, 120(3), 298-304, March 1990 Abstract
  • Silberhorn EM, Glauert HP, Robertson LW, Carcinogenicity of polyhalogenated biphenyls: PCBs and PBBs, Critical Reviews in Toxicology, 20(6), 440-96, 1990 Abstract
  • Borges T, Glauert HP, Chen LC, Chow CK, Robertson LW, Effect of the peroxisome proliferator perfluorodecanoic acid on growth and lipid metabolism in Sprague Dawley rats fed three dietary levels of selenium, Archives of Toxicology, 64(1), 26-30, 1990 Abstract
  • Nishihara Y, Iwaka M, Puttman M, Robertson LW, Utsumi K, Effects of hexachlorobiphenyls on the functions of rat liver mitochondria, Pharmacol. (Life Sci. Adv.), 9, 249-262, 1990
  • Azais-Braesco V, Macaire JP, Bellenand P, Robertson LW, Pascal G, Effects of two prototypic polychlorinated biphenyls (PCBs) on lipid composition of rat liver and serum, Journal of Nutrition Biochemistry, 1, 350-354, 1990
  • Swierenga SHH, Yamasaki H, Picoli C, Robertson LW, Bourgon L, Marceau N, Fitzgerald DJ, Effects on inter-cellular communication in human keratinocytes and liver-derived cells of polychlorinated biphenyl cogeners with differing in vivo pormotion activities, Carcinogenesis, 11, 921-926, 1990
  • Steinberg P, Schramm H, Schladt L, Robertson LW, Thomas H, Oesch F, The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells, Biochemical Journal, 264(3), 737-44, December 1989 Abstract
  • Rodman LE, Shedlofsky SI, Swim AT, Robertson LW, Effects of polychlorinated biphenyls on cytochrome P450 induction in the chick embryo hepatocyte culture, Archives of Biochemistry and Biophysics, 275(1), 252-62, November 1989 Abstract
  • Borlakoglu JT, Edwards-Webb JD, Dils RR, Wilkins JP, Robertson LW, Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls, Febs Letters, 247(2), 327-9, April 1989 Abstract
  • Grolier P, Cassand P, Antignac E, Narbonne JF, Albrecht R, Azais V, Robertson LW, Oesch F, Effects of prototypic PCBs on benzo[a]pyrene mutagenic activity related to vitamin A intake, Mutation Research, 211(1), 139-45, March 1989 Abstract
  • Schramm H, Friedberg T, Robertson LW, Oesch F, Kissel W, Perfluorodecanoic acid decreases the enzyme activity and the amount of glutathione S-transferases proteins and mRNAs in vivo, Chemico-biological Interactions, 70(1-2), 127-43, 1989 Abstract
  • Amelizad Z, Narbonne JF, Wolf CR, Robertson LW, Oesch F, Effect of nutritional imbalances on cytochrome P-450 isozymes in rat liver, Biochemical Pharmacology, 37(17), 3245-9, September 1988 Abstract
  • Dogra S, Filser JG, Cojocel C, Greim H, Regel U, Oesch F, Robertson LW, Long-term effects of commercial and congeneric polychlorinated biphenyls on ethane production and malondialdehyde levels, indicators of in vivo lipid peroxidation, Archives of Toxicology, 62(5), 369-74, 1988 Abstract
  • Rauch P, Puttmann M, Oesch F, Okamoto Y, Robertson LW, Differential induction of cytochrome P-450 by the enantiomers of trans-stilbene oxide, Biochemical Pharmacology, 36(24), 4355-9, December 1987 Abstract
  • Amelizad Z, Narbonne JF, Borin C, Robertson LW, Periquet A, Oesch F, Effect of unbalanced diets on incorporation of delta-aminolevulinic acid into cytochrome P-450, FEBS Letters, 220(1), 231-5, August 1987 Abstract
  • Arand M, Robertson LW, Oesch F, A fluorometric assay for quantitating phenol sulfotransferase activities in homogenates of cells and tissues, Anal Biochem, 163(2), 546-51, June 1987 Abstract
  • Azais V, Arand M, Rauch P, Schramm H, Bellenand P, Narbonne JF, Oesch F, Pascal G, Robertson LW, A time-course investigation of vitamin A levels and drug metabolizing enzyme activities in rats following a single treatment with prototypic polychlorinated biphenyls and DDT, Toxicology, 44(3), 341-54, June 1987 Abstract
  • Nishihara Y, Robertson LW, Utsumi K, Studies of the influence of chloro-substituent sites in tetrachlorobiphenyls on the uncoupling of oxidative phosphorylation in isolated rat liver mitochondria, Chem Pharm Bull (tokyo), 35(4), 1587-95, April 1987 Abstract
  • Glatt HR, Robertson LW, Arand M, Rauch P, Schramm H, Setiabudi F, Pochlauer P, Muller EP, Oesch F, cis- and trans-1,2-diphenylaziridines: induction of xenobiotic-metabolizing enzymes in rat liver and mutagenicity in Salmonella typhimurium, Archives of Toxicology, 59(4), 242-8, December 1986 Abstract
  • Buchmann A, Kunz W, Wolf CR, Oesch F, Robertson LW, Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated r, Cancer Letters, 32(3), 243-53, September 1986 Abstract
  • Robertson LW, Chandrasekaran A, Reuning RH, Hui J, Rawal BD, Reduction of digoxin to 20R-dihydrodigoxin by cultures of Eubacterium lentum, Applied and Environmental Microbiology, 51(6), 1300-3, June 1986 Abstract
  • Nishihara Y, Robertson LW, Oesch F, Utsumi K, The effects of tetrachlorobiphenyls on the electron transfer reaction of isolated rat liver mitochondria, Life Sciences, 38(7), 627-35, February 1986 Abstract
  • Schramm H, Robertson LW, Oesch F, Differential regulation of hepatic glutathione transferase and glutathione peroxidase activities in the rat, Biochemical Pharmacology, 34(20), 3735-9, October 1985 Abstract
  • Nishihara Y, Robertson LW, Oesch F, Utsumi K, Interaction of tetrachlorobiphenyls with isolated rat liver mitochondria, Journal of Pharmacobiodyn, 8(9), 726-32, September 1985 Abstract
  • Halvorson MR, Phillips TD, Safe SH, Robertson LW, Metabolism of aflatoxin B1 by rat hepatic microsomes induced by polyhalogenated biphenyl congeners, Applied and Environmental Microbiology, 49(4), 882-6, April 1985 Abstract
  • Robertson LW, Regel U, Filser JG, Oesch F, Absence of lipid peroxidation as determined by ethane exhalation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD), Archives of Toxicology, 57(1), 13-6, April 1985 Abstract
  • Shepherd EC, Phillips TD, Irvin TR, Safe SH, Robertson LW, Aflatoxin B1 metabolism in the rat: polyhalogenated biphenyl enhanced conversion to aflatoxin M1, Xenobiotica, 14(9), 741-50, September 1984 Abstract
  • Robertson LW, Thompson K, Parkinson A, Synthesis, characterization and biologic effects of polybrominated naphthalenes, Archives of Toxicology, 55(2), 127-31, July 1984 Abstract
  • Robertson LW, Parkinson A, Bandiera S, Lambert I, Merrill J, Safe SH, PCBs and PBBs: biologic and toxic effects on C57BL/6J and DBA/2J inbred mice, Toxicology, 31(3-4), 191-206, June 1984 Abstract
  • Parkinson A, Thomas PE, Ryan DE, Reik LM, Safe SH, Robertson LW, Levin W, Differential time course of induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by Aroclor 1254, Archives of Biochemistry and Biophysics, 225(1), 203-15, August 1983 Abstract
  • Parkinson A, Robertson LW, Safe SH, Induction of rat hepatic microsomal cytochrome P-450 by 2,3',4,4',5,5'-hexachlorobiphenyl, Biochemical Pharmacology, 32(14), 2269-79, July 1983 Abstract
  • Parkinson A, Safe SH, Robertson LW, Thomas PE, Ryan DE, Reik LM, Levin W, Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activi, Journal of Biological Chemistry, 258(9), 5967-76, May 1983 Abstract
  • Robertson LW, Andres JL, Safe SH, Lovering SL, Toxicity of 3,3',4,4'- and 2,2',5,5'-tetrabromobiphenyl: correlation of activity with aryl hydrocarbon hydroxylase induction and lack of protection by antioxidants, Journal of Toxicology and Environmental Health, 11(1), 81-91, January 1983 Abstract
  • Parkinson A, Robertson LW, Safe S, Binding of metyrapone to dithionite-reduced cytochrome P-450 from rats treated with xenobiotics, Biochemical Pharmacology, 31(21), 3489-94, November 1982 Abstract
  • Robertson LW, Parkinson A, Campbell MA, Safe S, Polybrominated biphenyls as aryl hydrocarbon hydroxylase inducers: structure-activity correlations, Chem Biol Interact, 42(1), 53-66, October 1982 Abstract
  • Safe S, Robertson LW, Safe L, Parkinson A, Bandiera S, Sawyer T, Campbell MA, Halogenated biphenyls: molecular toxicology, Canadian Journal of Physiology and Pharmacology, 60(7), 1057-64, July 1982 Abstract
  • Robertson LW, Parkinson A, Bandiera S, Safe S, Potent induction of rat liver microsomal, drug-metabolizing enzymes by 2,3,3',4,4',5-hexabromobiphenyl, a component of fireMaster, Chem Biol Interact, 35(1), 13-24, April 1981 Abstract
  • Parkinson A, Robertson LW, Safe L, Safe S, Polychlorinated biphenyls as inducers of hepatic microsomal enzymes: effects of di-ortho substitution, Chem Biol Interact, 35(1), 1-12, April 1981 Abstract
  • Parkinson A, Robertson LW, Safe S, Further characterization and applications of the 4-chlorobiphenyl hydroxylase assay, Advanced Experimental Medicine and Biology, 136 Pt A, 753-9, 1981 Abstract
  • Robertson LW, Parkinson A, Chittim B, Bandiera S, Sawyer TW, Safe S, Aryl hydrocarbon hydroxylase (AHH) induction by polybrominated biphenyls (PBBs): enchancement by photolysis, Toxicology, 22(2), 103-14, 1981 Abstract
  • Parkinson A, Robertson LW, Safe S, Hepatic microsomal enzyme induction by 2,2', 3,3', 4,4'- and 2,2', 3', 4,4', 5-hexachlorobiphenyl, Life Sciences, 27(24), 2333-7, December 1980 Abstract
  • Parkinson A, Robertson LW, Safe S, Reconstituted human breast milk PCBs as potent inducers of aryl hydrocarbon hydroxylase, Biochemical and Biophysical Research Communications, 96(2), 882-9, September 1980 Abstract
  • Robertson LW, Parkinson A, Safe S, Induction of both cytochromes P-450 and P-448 by 2,3',4,4',5-pentabromobiphenyl, a component of fireMaster, Biochemical and Biophysical Research Communications, 92(1), 175-82, January 1980 Abstract

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