Lawrence D. True

powered by
COS Expertise®
University of Washington
School of Medicine
Pathology
Anatomic
Director of Urologic PathologyAppointed: 1991

Mailing Address

Box 356100
University of Washington
Seattle, Washington 98195
United States

Contact Information

Phone: (206) 598-4027
Fax: (206) 598-4928
ltrue@u.washington.edu

Qualifications

M.D., Tulane University, 1971.

Expertise and Research Interests

April 20004 - As a pathologist, I work in two domains – clinical and experimental. My research is focused on the prostate and urinary bladder. Using cell and tissue localization techniques (laser microdissection, flow cytometry, immunohistochemistry) and molecular techniques (expression arrays and proteomics), applied to both cell lines and to human tissue (both primary benign and malignant prostate and bladder, and prostate xenografts), I am interested in understanding the cellular and molecular mechanisms of prostate cancer, benign prostatic hypertrophy, and prostatitis. My clinical work is surgical pathology with a subspecialty focus on tumors of the prostate, urinary bladder, testis, and kidney.

Other Expertise

Image Analysis

Keywords

COS Keywords:

Genomics, Immunohistochemistry, Kidney (Renal) Functions, Kidney Disease, Microbiology, Nephrology, Pathology, Prostate Cancer, Proteomics, Virology.

Additional Terms:

Benign Prostatic Hypertrophy, Bladder Cancer, Genomics, Prostate Cancer, Prostatitis, Proteomics.

Publications

  • Lin B, Ferguson C, White JT, Wang S, Vessella R, True LD, Hood L, Nelson PS, Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2., Cancer Research, 59(17), 4180-4, 1 Sep 1999 Abstract
  • Liu AY, True LD, LaTray L, Ellis WJ, Vessella RL, Lange PH, Higano CS, Hood L, van den Engh G, Analysis and sorting of prostate cancer cell types by flow cytometry., Prostate, 40(3), 192-9, 1 Aug 1999 Abstract
  • Folpe AL, Tsue T, Rogerson L, Weymuller E, Oda D, True LD, Odontogenic ghost cell carcinoma: a case report with immunohistochemical and ultrastructural characterization., Journal of Oral Pathology and Medicine, 27(4), 185-9, 1998 Abstract
  • Nelson P S, Plymate S R, Wang K, True L D, Ware J L, Gan L, Liu A Y, Hood L, Hevin, an antiadhesive extracellular matrix protein, is down-regulated in metastatic prostate adenocarcinoma., Cancer Research, 58(2), 232-6, 15 Jan 1998 Abstract
  • Fraga C H, True L D, Kirk D, Enhanced expression of the mesenchymal marker, vimentin, in hyperplastic versus normal human prostatic epithelium., Journal of Urology, 159(1), 270-4, Jan 1998 Abstract
  • Nelson P S, Ng W L, Schummer M, True L D, Liu A Y, Bumgarner R E, Ferguson C, Dimak A, Hood L, An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones., Genomics, 47(1), 12-25, 1 Jan 1998 Abstract
  • Liu A Y, True L D, LaTray L, Nelson P S, Ellis W J, Vessella R L, Lange P H, Hood L, van den Engh G, Cell-cell interaction in prostate gene regulation and cytodifferentiation., Proceedings of the National Academy of Sciences (USA), 94(20), 10705-10, 30 Sep 1997 Abstract
  • Liu K J, Chatta G S, Twardzik D R, Vedvick T S, True L D, Spies A G, Cheever M A, Identification of rat prostatic steroid-binding protein as a target antigen of experimental autoimmune prostatitis: implications for prostate cancer therapy., Journal of Immunology, 159(1), 472-80, 1 Jul 1997 Abstract
  • Santucci R A, True L D, Lange P H, Is partial cystectomy the treatment of choice for mucinous adenocarcinoma of the urachus?, Urology, 49(4), 536-40, April 1997 Abstract
  • Liu A Y, Corey E, Vessella R L, Lange P H, True L D, Huang G M, Nelson P S, Hood L, Identification of differentially expressed prostate genes: increased expression of transcription factor ETS-2 in prostate cancer., Prostate, 30(3), 145-53, 15 Feb 1997 Abstract
  • Bladou F, Vessella R L, Buhler K R, Ellis W J, True L D, Lange P H, Cell proliferation and apoptosis during prostatic tumor xenograft involution and regrowth after castration., International Journal of Cancer, 67(6), 785-90, 17 Sep 1996 Abstract
  • Ellis WJ, Vessella RL, Buhler KR, Bladou F, True LD, Bigler SA, Curtis D, Lange PH, Characterization of a novel androgen-sensitive, prostate-specific antigen-producing prostatic carcinoma xenograft: LuCaP 23., Clinical Cancer Research, 2(6), 1039-48, June 1996 Abstract
  • True L D, Morphometric applications in anatomic pathology., Human Pathology, 27(5), 450-67, May 1996 Abstract
  • Tsue T T, Wood D E, True L D, Weymuller E A Jr, Male presenting with hoarseness and a thyroid mass., American Journal of Otolaryngology, 16(3), 158-64, May 1995 Abstract
  • True L D, Surgical pathology examination of the prostate gland. Practice survey by American society of clinical pathologists [published erratum appears in Am J Clin Pathol 1995 Mar;103(3):376], American Journal of Clinical Pathology, 102(5), 572-9, November 1994 Abstract
  • Takayama T K, Vessella R L, Brawer M K, True L D, Noteboom J, Lange P H, Urinary prostate specific antigen levels after radical prostatectomy., Journal of Urology, 151(1), 82-7, January 1994 Abstract
  • Burmer G C, True L D, Krieger J N, Squamous cell carcinoma of the scrotum associated with human papillomaviruses., Journal of Urology, 149(2), 374-7, February 1993 Abstract
  • Takayama T K, Krieger J N, True L D, Lange P H, Recurrent prostate cancer despite undetectable prostate specific antigen., Journal of Urology, 148(5), 1541-2, November 1992 Abstract
  • Grace M P, Kim K H, True L D, Fuchs E, Keratin expression in normal esophageal epithelium and squamous cell carcinoma of the esophagus., Cancer Research, 45(2), 841-6, February 1985 Abstract

Profile Details

Last Updated: 2/14/2005

COS Expertise ID #307997
Reference this profile directly: http://myprofile.cos.com/ldtrue