Dr. Åke Lernmark

(Reading, Writing, Speaking)

National Institutes of Health (NIH): Genetic control of BB rat autoimmunity., $3,989,731, Sep 15, 2000 to Aug 31, 2005.
Juvenile Diabtes Research Foundation: Dissection Age-Dependent Type 1 Diabetes Risk by Multilocus SNP Analysis., $300,000, Sep 1, 2001 to Jun 30, 2004.
Juvenile Diabetes Research Foundation: Epitope Specificity to GAD65 Will Lead to a Better Understanding of the Mechanism Leading to Type 1 Diabetes., $120,000, Jul 1, 1999 to Jun 30, 2003.
Juvenile Diabetes Foundation International: T Cell Rescue Following Bone-Marrow Transplantation Between BB rats Congenic for the Lymphopenia Gene., $330,000, Jan 1, 2001 to Dec 31, 2004.
National Institutes of Health (NIH): Immunogenetics of human diabetes., $4,379,032, Dec 1, 1997 to Nov 30, 2002.
National Institutes of Health (NIH): Islet cell membrane antibodies in diabetes., $994,488, Apr 1, 2000 to Nov 30, 2004.

• Stigbrand T, Rymo L, Lernmark A (Sep 2005) [The Medical Biobank--a unique resource for medical research], Lakartidningen, 102 (39), 2769-72
• Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA (Aug 2005) Aberrancies in the differentiation and maturation of dendritic cells from bone-marrow precursors are linked to various genes on chromosome 4 and other chromosomes of the BB-DP rat., Journal of Autoimmunity, 25 (1), 1-12
• Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA (Aug 2005) Defects in differentiation of bone-marrow derived dendritic cells of the BB rat are partly associated with IDDM2 (the lyp gene) and partly associated with other genes in the BB rat background., Journal of Autoimmunity, 25 (1), 46-56
• Larsson HE, Lynch K, Lernmark B, Nilsson A, Hansson G, Almgren P, Lernmark A, Ivarsson SA, DiPiS Study Group (Aug 2005) Diabetes-associated HLA genotypes affect birthweight in the general population., Diabetologia, 48 (8), 1484-91
• Padoa CJ, Crowther NJ, Thomas JW, Hall TR, Bekris LM, Torn C, Landin-Olsson M, Ortqvist E, Palmer JP, Lernmark A, Hampe CS (Jun 2005) Epitope analysis of insulin autoantibodies using recombinant Fab., Clinical and Experimental Immunology, 140 (3), 564-71
• Sweet IR, Cook DL, Lernmark A, Greenbaum CJ, Wallen AR, Marcum ES, Stekhova SA, Krohn KA, Systematic Screening of Potential Beta-cell Imaging Agents., Biochemical and Biophysical Research Communications, 314(4), 976-83, Feb 2004
• Niklasson B, Heller KE, Schønecker B, Bildsøe M, Daniels T, Hampe, CS, Widlund P, Simonson WT, Schaefer JB, Rutledge E, Bekris L, Lindberg AM, Johansson S, Örtqvist E, Persson B, Lernmark Å, Development of Type 1 Diabetes in Wild Bank Voles Associated With Islet Autoantibodies and the Novel Ljungan Virus, Int J Exp Diabetes Res., 4, 35-44, 9 Jan 2003
• Agardh D, Borulf S, Lernmark Å, and Ivarsson S.A., Tissue transglutaminase immunoglobulin isotypes in children with untreated and treated celiac disease, Journal of Pediatric Gastroenterology and Nutrition, 36, 77-82, 2003
• Elfving AM, Lindberg BA, Landin-Olsson M, Hampe CS, Hammerle LP, Lernmark Å, Ivarsson S-A., Islet cell autoantibodies in cord blood from children with blood group incompatibility or hyperbilirubinemia, Autoimmunity, 36, 111-125, 2003
• Rolandsson O, Hägg E, Janer M. Rutledge E, Gaur LK, Nilsson M, Hallmans G, Lernmak Å., High GAD65 autoantibody levels in nondiabetic adults are associated with HLA but not with CTLA-4 or INS VNTR, Journal of Intern. Medicine, 253, 447-453, 2003
• Gupta M, Nikitina-Zake L, Zarghami M, Landin-Olsson M, Kockum I, Lernmark Å and Sanjeevi CB., Association between the transmembrane region polymorphism of MHC Class I chain related gene-A and type 1 diabetes mellitus in Sweden, Human Immunology, 64, 553-561, 2003
• Hampe CS, Kockum I, Landin-Olsson M, Torn C, Ortqvist E, Persson B, Rolandsson O, Palmer J, Lernmark A, GAD65 antibody epitope patterns of type 1.5 diabetic patients are consistent with slow-onset autoimmune diabetes, Diabetes Care, 25(8), 1481-2, Aug 2002
• MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A, Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene, Genome Research, 12(7), 1029-39, July 2002
• Gaur LK, Kennedy E, Nitta Y, Nepom GT, Nelson KA, Allen M, Lernmark A, Induction of donor-specific tolerance to islet allografts in nonhuman primates, Annals of the New York Academy of Sciences, 958, 194-8, April 2002
• Gaur LK, Nitta Y, Kennedy E, Lernmark A, Nelson KA, Allen M, Nepom GT, Induction of islet allotolerance in nonhuman primates, Annals of the New York Academy of Sciences, 958, 199-203, April 2002
• Sanjeevi CB, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark A, The combination of several polymorphic amino acid residues in the DQalpha and DQbeta chains forms a domain structure pattern and is associated with insulin-dependent diabetes mellitus, Annals of the New York Academy of Sciences, 958, 362-75, April 2002
• Hampe CS, Hammerle LP, Bekris L, Örtqvist E, Persson B and Lernmark Å., Stable GAD65 autoantibody epitope patterns in type 1 diabetes children five years after onset, Journal of Autoimmunity, 18, 49-53, 2002
• Agardh D, Nilsson A, Carlsson A, Kockum I, Lernmak Å and Ivarsson S-A., Tissue transglutaminase autoantibodies and human leucocyte antigen in Down's syndrome patients with coeliac disease, Acta Paediatrica, 9, 34-38, 2002
• Clark L, Greenbaum C, Jiang J, Lernmark Å and Och H., The antibody response to bacteriophage is linked to the lymphopenia gene in congenic BioBreeding rats, FEMS, 32, 205-209, 2002
• Maioli M, Tonolo G, Bekris L, Cirillo R, Schranz D, Cossu E, Ciccarese M, Lernmark Å., GAD65 but not IA-2 autoantibodies are common in siblings of Sardinian type 2 diabetic families, Diabetes Research and Clinical Practice, 56, 41-47, 2002
• Graham J, Hagopian WA, Kockum I, Li LS, Sanjeevi CB, Lowe RM, Schaefer JB, Zarghami M, Day HL, Landin-Olsson M, Palmer JP, Janer-Villanueva M, Hood L, Sundkvist G, Lernmark Å, Breslow N, Dahlquist G, SCDSG, Göran Blohmé, DISS, Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes, Diabetes, 51, 1346-1355, 2002
• Mohatt J, Gilliam LK, Bekris L, Ebbeson S, Lernmark Å., Type 1 diabetes-related autoantibodies are rare in Alaskan native populations, International Journal of Circumpolar Health, 61, 21-31, 2002
• Simonson W, Ramanathan S, Bieg S, Poussier P and Lernmark Å., Protein-free diets do not protect high incidence diabetes-prone BB rats from diabetes, Metabolism, 551, 569-574, 2002
• Sweet, Dynamic perifusion to maintain and assess isolated pancreaic islets, Diabetes Technology and Therapeutics, 4, 67-76, 2002
• Sims TJ, Lernmark Å, Mancl LA, Schifferle RE, Page RC Person GR, Serum IgG to heat shock proteins and Porphyromonas gingivalis antigens in diabetic patients with periodontitis, Journal of Clinical Periodontology, 29, 550-560, 2002
• Mei Q, Mundinger TO, Lernmark Å, Taborsky GJ, Jr., Early, selective, and marked loss of sympathetic nerves from the islets of biobreeder diabetic rats, Diabetes, 51, 2997-3002, 2002
• Rolandson O, Haney MF, Hägg E, Biber B and Lernmak Å, Streptozotocin induced diabetes in minipig: A case report of a possible model for type 1 diabetes?, Autoimmunity, 35, 261-264, 2002
• Plesner A, Greenbaum CJ, Gaur LK, Enst RK, Lernmark Å, Macrophages from high risk HLA DQB1*0201/0302 type 1 diabetes paients are hypersensiive to lipopolysaccharide stimulation, Scandinavian Journal of Immunology, 56, 522-529, 2002
• Hampe CS, Kockum I, Landin-Olsson M, Törn C, Örtqvist E, Persson O, Rolandsson O, Palmer JP and Lenmark Å, GAD65 antibody epitope patterns of patients with Type 1.5 differ from that of Type 1 diabetes patients, Diabetes Care, 25, 1481-1482, 2002
• Novak EJ, Masewicz SA, Liu AW, Lernmark A, Kwok WW, Nepom GT, Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset, International Immunology, 13(6), 799-806, June 2001
• Barry SC, Ramesh N, Lejnieks D, Simonson WT, Kemper L, Lernmark A, Osborne WR, Glucose-regulated insulin expression in diabetic rats, Human Gene Therapy, 12(2), 131-9, 2001
• Hampe CS, Hammerle LP, Falorni A, Robertson J, Lernmark A, Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding, Febs Letters, 488(3), 185-9, 2001
• Hampe CS, Lundgren P, Daniels TL, Hammerle LP, Marcovina SM and Lernmark Å., A novel monoclonal antibody specific for the N-terminal end of GAD65, Journal of Neuroimmunology, 113, 63-71, 2001
• Törn, C, Landin-Olsson M, Lernmark Å, Schersten A, Östman J, Arnqvist HJ, Bjork E, Blohme G, Bolinder J, Eriksson J, Littorin B, Nystrom L. and Sundkvist G., Combinations of beta cell specific autoantibodies at diagnosis of diabetes in young adults reflects different courses of beta cell damage, Autoimmunity, 33, 115-120, 2001
• Rolandsson O, Hägg E, Nilsson M, Hallmans G, Mincheva-Nilsson L, Lenmark Å., Prediction of diabetes with body mass index, oral glucose tolerance test and islet cell autoantibodies in a regional population, Journal of Internal Medicine, 249, 279-288, 2001
• Agardh D, Nilsson A, Tuomi T, Lindberg B, Carlsson A, Lernmark Å, and Ivarsson S., Prediction of Silent Celiac Disease at Diagnosis of Childhood Type 1 Diabetes by Tissue Transglutaminase Autoantibodies and HLA, Pediatric Diabetes, 2, 58, 2001
• Gaur LK, Nepom GT, Lernmark Å., Low-dose streptozotocin induces sustained hyperglycemia in Macaque nemestrina, Journal of Autoimmunity, 33, 103-114, 2001
• Sims TJ, Lernmark Å, Smith T, Page RC, Persson GR., Treatment outcome for IDDM patients in relation to glutamic acid decarboxylase autoantibodies and serum IgG to periodontal pathogens, Journal of Periodontology, 28, 550-557, 2001
• Plesner A, Greenbaum CJ. and Lernmark Å., Low serum conditions for in vitro generation of human macrophages with macrophage-colony stimulating factor, Journal of Immunological Methods, 249, 53-61, 2001
• Uibo R, Sullivan EP, Uibo O, Lernmark Å, Salur L, Kivik T, Mandel M., Comparison of the prevalence of glutamic acid decarboxylase (GAD65) and gliadin antibodies (AGA) in a randomly selected adult Estonian population, Hormone and Metabolic Research, 33, 103-114, 2001
• Hoeldtke RD, Bryner KD, Hobbs GR, Horvath GG, Riggs JE, Christie I, Ganser G, Marcovina SM, Lernmark A, Antibodies to glutamic acid decarboxylase and peripheral nerve function in type 1 diabetes, Journal of Clinical Endocrinology and Metabolism, 85(9), 3297-308, September 2000
• Schranz DB, Bekris L, Landin-Olsson M, Torn C, Nilang A, Toll A, Sjostrom J, Gronlund H, Lernmark A, Newly diagnosed latent autoimmune diabetes in adults (LADA) is associated with low level glutamate decarboxylase (GAD65) and IA-2 autoantibodies. Diabetes Incidence Study in Sweden (DISS), Hormone and Metabolic Research, 32(4), 133-8, April 2000
• Chessler SD, Lernmark A, Alternative splicing of GAD67 results in the synthesis of a third form of glutamic-acid decarboxylase in human islets and other non-neural tissues, Journal of Biological Chemistry, 275(7), 5188-92, February 2000
• Bieg S, Simonson W, Ellefsen K, Lernmark A, Rel B is an early marker of autoimmune islet inflammation in the biobreeding (BB) rat, Pancreas, 20(1), 47-54, Jan 2000
• Östman J, Landin-Olsson M, Törn C, Palmer J, Lernmark Å, Arnqvist H, Bjork E, Bolinder J, Bohme G, Eriksson J, Littorin B, Nyström L, Schersten B, Sundkvist G, Wibell L., Ketoacidosis in young adults is not related to the islet cell antibodies at the diagnosis of Type 1 diabetes mellitus--a nationwide study, Diabetic Medicine, 17, 269-274, 2000
• Marcovina SM, Landin-Olsson M, Essen-Möller A, Palmer JP, Lernmark Å, Evaluation of a novel radioimmunoassay using 125I-labelled human recombinant GAD65 for the determination of glutamic acid decarboxylae (GAD65) autoantibodies, International Journal of Clinical and Laboratory Research, 30, 21-26, 2000
• Novak EJ, Ortqvist E, Nord E, Edwall L, Hampe CS, Bekris L, Persson BE and Lernmark Å., Stability of disease-associated antibody titers in pregnant women with type 1 diabetes with or without residual beta-cell function, Diabetes Care, 23, 1019-1021, 2000
• Mire-Sluis AT, Das RG, Lernmark Å and Participants of the Study., The World Health Organisation International Collaborative Study for Islet Cell antibodies, Diabetologia, 43, 1282-1294, 2000
• Reijonen H, Daniels TL, Lernmark Å, Nepom GT., GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65, Diabetes, 49, 1621-1626, 2000
• Lowe RM, Graham J, Sund G, Kockum I, Landin-Olsson M, Schaefer JB, Törn C, Lernmark Å, Dahlquist G. for the Swedish Childhood Diabetes Study Group and Göran Blohmé for the Diabetes Incidence in Sweden Study Group., The length of the CTLA-4 microsatellite (AT)n-repeat by affects the risk for Type 1 diabetes, Autoimmunity, 32, 173-180, 2000
• Hampe CS, Hammerle LP, Örtqvist E, Kockum I, Rolandsson O, Landin-Olsson M, Törn, Recognition of glutamic acid decaboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes, Journal of Clinical Endocrinology and Metabolism, 85, 4671-4679, 2000
• Hao W, Davis C, Daniels T, Hampe CS, Lernmark A, Epitope-specific glutamic acid decarboxylase-65 autoantibodies in intravenous immunoglobulin preparations, Transfusion Medicine, 9(4), 307-10, December 1999
• Undlien DE, Kockum I, Ronningen KS, Lowe R, Saanjeevi CB, Graham J, Lie BA, Akselsen HE, Lernmark A, Thorsby E, HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes, Tissue Antigens, 54(6), 543-51, December 1999
• Lindberg B, Ivarsson SA, Lernmark A, Islet autoantibodies in cord blood could be a risk factor for future diabetes [letter], Diabetologia, 42(11), 1375, November 1999
• Kockum I, Sanjeevi CB, Eastman S, Landin-Olsson M, Dahlquist G, Lernmark A, Complex interaction between HLA DR and DQ in conferring risk for childhood type 1 diabetes, European Journal of Immunogenetics, 26(5), 361-72, October 1999
• Hampe CS, Ortqvist E, Persson B, Schranz DB, Lernmark A, Glutamate decarboxylase (GAD) autoantibody epitope shift during the first year of type 1 diabetes, Hormone and Metabolic Research, 31(10), 553-7, October 1999
• Klaff LS, Koike G, Jiang J, Wang Y, Bieg S, Pettersson A, Lander E, Jacob H, Lernmark A, BB rat diabetes susceptibility and body weight regulation genes colocalize on chromosome 2, Mammalian Genome, 10(9), 883-7, September 1999
• Hao W, Davis C, Hirsch IB, Eng LJ, Daniels T, Walsh D, Lernmark A, Plasmapheresis and immunosuppression in stiff-man syndrome with type 1 diabetes: a 2-year study [letter], Journal of Neurology, 246(8), 731-5, August 1999
• Lindberg B, Ahlfors K, Carlsson A, Ericsson UB, Landin-Olsson M, Lernmark A, Ludvigsson J, Sundkvist G, Ivarsson SA, Previous exposure to measles, mumps, and rubella--but not vaccination during adolescence--correlates to the prevalence of pancreatic and thyroid autoantibodies, Pediatrics, 104(1), e12, July 1999
• Rolandsson O, Hagg E, Hampe C, Sullivan EP Jr, Nilsson M, Jansson G, Hallmans G, Lernmark A, Glutamate decarboxylase (GAD65) and tyrosine phosphatase-like protein (IA-2) autoantibodies index in a regional population is related to glucose intolerance and body mass index, Diabetologia, 42(5), 555-9, May 1999
• Moore JK, Gold DP, Dreskin SC, Lernmark A, Bellgrau D, A diabetogenic gene prevents T cells from receiving costimulatory signals, Cellular Immunology, 194(1), 90-7, May 1999
• Graham J, Kockum I, Sanjeevi CB, Landin-Olsson M, Nystrom L, Sundkvist G, Arnqvist H, Blohme G, Lithner F, Littorin B, Schersten B, Wibell L, Ostman J, Lernmark A, Breslow N, Dahlquist G, Negative association between type 1 diabetes and HLA DQB1*0602-DQA1*0102 is attenuated with age at onset. Swedish Childhood Diabetes Study Group, European Journal of Immunogenetics, 26(2-3), 117-27, 1999
• Roep BO, Stobbe I, Duinkerken G, van Rood JJ, Lernmark A, Keymeulen B, Pipeleers D, Claas FH, de Vries RR, Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients, Diabetes, 48(3), 484-90, March 1999
• Littorin B, Sundkvist G, Hagopian W, Landin-Olsson M, Lernmark A, Ostman J, Arnqvist HJ, Blohme G, Bolinder J, Eriksson JW, Lithner F, Schersten B, Wibell L, Islet cell and glutamic acid decarboxylase antibodies present at diagnosis of diabetes predict the need for insulin treatment. A cohort study in young adults whose disease was initially labeled as typ, Diabetes Care, 22(3), 409-12, March 1999
• Nikoshkov A, Falorni A, Lajic S, Laureti S, Wedell A, Lernmark k, Luthman H, A conformation-dependent epitope in Addison's disease and other endocrinological autoimmune diseases maps to a carboxyl-terminal functional domain of human steroid 21-hydroxylase, Journal of Immunology, 162(4), 2422-6, February 1999
• Lee ES, Jiang J, Sund GC, Simonson WT, Graham J, Dietsch G, Schimpf B, Bieg S, Peterman G, Lernmark A, Recombinant human platelet-activating factor acetylhydrolase reduces the frequency of diabetes in the diabetes-prone BB rat, Diabetes, 48(1), 43-9, Jan 1999
• Landin-Olsson M, Arnqvist HJ, Blohme G, Littorin B, Lithner F, Nystrom L, Schersten B, Sundkvist G, Wibell L, Ostman J, Lernmark A, Appearance of islet cell autoantibodies after clinical diagnosis of diabetes mellitus, Autoimmunity, 29(1), 57-63, 1999
• Laureti S, Aubourg P, Calcinaro F, Rocchiccioli F, Casucci G, Angeletti G, Brunetti P, Lernmark A, Santeusanio F, Falorni A, Etiological diagnosis of primary adrenal insufficiency using an original flowchart of immune and biochemical markers, Journal of Clinical Endocrinology and Metabolism, 83(9), 3163-8, September 1998
• Bieg S, Koike G, Jiang J, Klaff L, Pettersson A, MacMurray AJ, Jacob HJ, Lander ES, Lernmark A, Genetic isolation of iddm 1 on chromosome 4 in the biobreeding (BB) rat, Mammalian Genome, 9(4), 324-6, April 1998
• Schranz D B, Bekris L, Landin-Olsson M, Torn C, Nilang A, Toll A, Gronlund H, Toivola B, Lernmark A, A simple and rapid microSepharose assay for GAD65 and ICA512 autoantibodies in diabetes. Diabetes Incidence Study in Sweden (DISS), Journal of Immunological Methods, 213(1), 87-97, 1 Apr 1998
• Sanjeevi CB, Hagopian WA, Landin-Olsson M, Kockum I, Woo W, Palmer JP, Lernmark Å, Dahlquist G., Association between autoantibody marker and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4, Tissue Antigens, 51, 281-286, 1998
• Hirsch IB, D'Alessio D, Eng L, Davis C, Lernmark Å and Chait A., Case report: Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro, Diabetes Research and Clinical Practice, 41, 197-202, 1998
• Verge CF, Stenger D, Bonifacio E, Colman PG, Pilcher C, Bingley PJ, Eisenbarth GS and participating laboratories., Combined use of autoantibodies (IA-2ab, GADab, IAA, ICA) in Type 1 diabetes: Combinatorial islet autoantibody workshop, Diabetes, 47, 1857-1866, 1998
• Hoeldtke RD, Bryner KD, Horvath GG, Byerly MR, Hobbs GR, Marcovina SM, Lernmark Å, Antibodies to GAD and glutamic control in recent-onset IDDM, 20(12), 1900-3, December 1997
• Dotta F, Falorni A, Tiberti C, Dionisi S, Anastasi E, Torresi P, Lernmark Å, Di Mario U, Autoantibodies to the GM2-1 islet ganglioside and to GAD-65 at type 1 diabetes onset, Journal of Autoimmunity, 10(6), 585-588, December 1997
• Ortqvist E, Falorni A, Scheynius A, Persson B, Lernmark A, Age governs gender-dependent islet cell autoreactivity and predicts the clinical course in childhood IDDM, Acta Paediatrica, 86(11), 1166-71, November 1997
• Vandewalle CL, Falorni A, Lernmark A, Goubert P, Dorchy H, Coucke W, Semakula C, Van der Auwera B, Kaufman L, Schuit F C, Pipeleers D G, Gorus F K, Associations of GAD65- and IA-2- autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry, Diabetes Care, 20(10), 1547-52, October 1997
• Lernmark A, Eisenbarth G, Ducat L, Erlich H A, Faustman D, Maclaren N K, Ott J, Permutt M A, She J X, Todd J, Family cell lines available for research--an endangered resource?, American Journal of Human Genetics, 61(3), 778-9, September 1997
• Lotfi K, Sund G, Lowe R, Graham J, Landin-Olsson M, Kockum I, Deeb S, Lernmark A, The beta cell glucokinase promoter variant is an unlikely risk factor for diabetes mellitus. Diabetes Incidence Study in Sweden (DISS), Diabetologia, 40(8), 959-62, August 1997
• Sanjeevi C B, DeWeese C, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark A, Lybrand T P, Analysis of critical residues of HLA-DQ6 molecules in insulin-dependent diabetes mellitus, Tissue Antigens, 50(1), 61-5, July 1997
• Bieg S, Moller C, Olsson T, Lernmark A, The lymphopenia (lyp) gene controls the intrathymic cytokine ratio in congenic BioBreeding rats, Diabetologia, 40(7), 786-92, July 1997
• Lernmark A, Regulation of islet growth: reports from the Second Seattle Islet Symposium, Hormone and Metabolic Research, 29(6), 264, June 1997
• Ivarsson SA, Ackefors M, Carlsson A, Ekberg G, Falorni A, Kockum I, Landin-Olsson M, Lernmark Å, Lindberg B, Sundkvist G, and Svanberg L, Glutamate decarboxylase antibodies in non-diabetic prgnancy precedes insulin-dependent diabetes in the mother but not necessarily in the offspring, Autoimmunity, 26, 261-269, 1997
• Lernmark A, Immune surveillance: paraneoplastic or environmental triggers of autoimmunity, Critical Reviews In Immunology, 17(5-6), 437-47, 1997
• Sanjeevi, C.B., DeWeese, C., Landin-Olsson, M., Kockum, I., Dahlquist, G., Lernmark, Å., and Lybrand, T.P., Analysis of critical residues of HLA-DQ6 molecules in insulin-dependent diabetes mellitus, Tissue Antigens, 50, 61-65, 1997
• Bieg, S., Moller, C., Olsson, T., and Lernmark, Å., The lymphopenia (lyp) gene controls the intrathymic cytokine ratio in congenic BioBreeding rats., Diabetologia, 40, 786-790, 1997
• Ivarsson S A, Ackefors M, Carlsson A, Ekberg G, Falorni A, Kockum I, Landin-Olsson M, Lernmark A, Lindberg B, Sundkvist G, Svanberg L, Glutamate decarboxylase antibodies in non-diabetic pregnancy precedes insulin-dependent diabetes in the mother but not necessarily in the offspring, Autoimmunity, 26(4), 261-9, 1997
• Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark Å, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ, Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401, Journal of Clinical Investigation, 98(11), 2597-603, December 1996
• Sanjeevi C B, Hjelmstrom P, Hallmans G, Wiklund F, Lenner P, Angstrom T, Dillner J, Lernmark A, Different HLA-DR-DQ haplotypes are associated with cervical intraepithelial neoplasia among human papillomavirus type-16 seropositive and seronegative Swedish women, International Journal of Cancer, 68(4), 409-14, 15 Nov 1996
• Lernmark A, Glutamic acid decarboxylase--gene to antigen to disease, Journal of Internal Medicine, 240(5), 259-77, November 1996
• Agardh D, Gaur L K, Agardh E, Landin-Olsson M, Agardh C D, Lernmark A, HLA-DQB1*0201/0302 is associated with severe retinopathy in patients with IDDM, Diabetologia, 39(11), 1313-7, November 1996
• Kobayashi T, Oka Y, Katagiri H, Falorni A, Kasuga A, Takei I, Nakanishi K, Murase T, Kosaka K, Lernmark A, Association between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243, Diabetologia, 39(10), 1196-200, October 1996
• Falorni A, Ackefors M, Carlberg C, Daniels T, Persson B, Robertson J, Lernmark A, Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM, Diabetologia, 39(9), 1091-8, September 1996
• Kockum I, Lernmark A, Dahlquist G, Falorni A, Hagopian W A, Landin-Olsson M, Li L C, Luthman H, Palmer J P, Sanjeevi C B, Sundkvist G, Ostman I J, Genetic and immunological findings in patients with newly diagnosed insulin-dependent diabetes mellitus. The Swedish Childhood Diabetes Study Group and The Diabetes Incidence in Sweden Study (DISS) Gr, Hormone and Metabolic Research, 28(7), 344-7, July 1996
• Ostman J, Lernmark A, Landin-Olsson M, Sundkvist G, Palmer J, Arnqvist H, Blohme G, Lithner F, Littorin B, Nystrom L, Schersten B, Wibell L, Autoimmune (type 1) diabetes in young adults in Sweden, Hormone and Metabolic Research, 28(7), 348-50, July 1996
• Graham J, Kockum I, Breslow N, Lernmark A, Holmberg E, A comparison of three statistical models for IDDM associations with HLA, Tissue Antigens, 48(1), 1-14, July 1996
• Kasuga A, Falorni A, Maruyama T, Ozawa Y, Grubin C E, Matsubara K, Takei I, Saruta T, Scheynius A, Lernmark A, HLA class II is associated with the frequency of glutamic acid decarboxylase M(r) 65,000 autoantibodies in Japanese patients with insulin-dependent diabetes mellitus, Acta Diabetologica, 33(2), 108-13, July 1996
• Tuomi T, Bjorses P, Falorni A, Partanen J, Perheentupa J, Lernmark A, Miettinen A, Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I, Journal of Clinical Endocrinology and Metabolism, 81(4), 1488-94, April 1996
• Sanjeevi C B, Hook P, Landin-Olsson M, Kockum I, Dahlquist G, Lybrand T P, Lernmark A, DR4 subtypes and their molecular properties in a population-based study of Swedish childhood diabetes, Tissue Antigens, 47(4), 275-83, April 1996
• Sanjeevi C B, Falorni A, Kockum I, Hagopian W A, Lernmark A, HLA and glutamic acid decarboxylase in human insulin-dependent diabetes mellitus, Diabetic Medicine, 13(3), 209-17, March 1996
• Kasuga A, Maruyama T, Ozawa Y, Takei I, Falorni A, Lernmark A, Saruta T, Antibody to the M(r) 65,000 isoform of glutamic acid decarboxylase are detected in non-insulin-dependent diabetes in Japanese, Journal of Autoimmunity, 9(1), 105-11, February 1996
• Hallengren B, Falorni A, Landin-Olsson M, Lernmark A, Papadopoulos K I, Sundkvist G, Islet cell and glutamic acid decarboxylase antibodies in hyperthyroid patients: at diagnosis and following treatment, Journal of Internal Medicine, 239(1), 63-8, January 1996
• Falorni, A., Ackefors, M., Carlberg, C., Daniels, T., Persson, B., Robertson, J., and Lernmark, Å., Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM, Diabetologia, 39, 1091-1098, 1996
• Wicker, L.S., Chen, S.L., Nepom, G.T., Elliott, J.F., Freed, D.C., Bansal, A., Zheng, S., Herman, A., Lernmark, Å., Zaller, D.M., Peterson, L.M., Rothbard, J.B., Cummings, R., and Whiteley, P.J., Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the Type 1 diabetes-associated human MHC Class II allele, DRB1*0401, Journal of Clinical Investigation, 98, 2597-2603, 1996
• Kockum I, Sanjeevi C B, Eastman S, Landin-Olsson M, Dahlquist G, Lernmark A, Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish children with insulin-dependent diabetes and controls, European Journal of Immunogenetics, 22(6), 443-65, December 1995
• Yu L, Chase H P, Falorni A, Rewers M, Lernmark A, Eisenbarth G S, Sexual dimorphism in transmission of expression of islet autoantibodies to offspring, Diabetologia, 38(11), 1353-7, November 1995
• Falorni A, Ortqvist E, Persson B, Lernmark A, Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands, Journal of Immunological Methods, 186(1), 89-99, 12 Oct 1995
• Falorni A, Nikoshkov A, Laureti S, Grenback E, Hulting A L, Casucci G, Santeusanio F, Brunetti P, Luthman H, Lernmark A, High diagnostic accuracy for idiopathic Addison's disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase, Journal of Clinical Endocrinology and Metabolism, 80(9), 2752-5, September 1995
• Pettersson A, Wilson D, Daniels T, Tobin S, Jacob H J, Lander E S, Lernmark A, Thyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes, Journal of Autoimmunity, 8(4), 493-505, August 1995
• Pettersson A, Winer E S, Weksler-Zangen S, Lernmark A, Jacob H J, Predictability of heterozygosity scores and polymorphism information content values for rat genetic markers, Mammalian Genome, 6(8), 512-20, August 1995
• Huang X, Yuang J, Goddard A, Foulis A, James R F, Lernmark A, Pujol-Borrell R, Rabinovitch A, Somoza N, Stewart T A, Interferon expression in the pancreases of patients with type I diabetes, Diabetes, 44(6), 658-64, June 1995
• Hagopian W A, Sanjeevi C B, Kockum I, Landin-Olsson M, Karlsen A E, Sundkvist G, Dahlquist G, Palmer J, Lernmark A, Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children, Journal of Clinical Investigation, 95(4), 1505-11, April 1995
• Vandewalle C L, Falorni A, Svanholm S, Lernmark A, Pipeleers D G, Gorus F K, High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years, Journal of Clinical Endocrinology and Metabolism, 80(3), 846-51, March 1995
• Dirkx R Jr, Thomas A, Li L, Lernmark A, Sherwin R S, De Camilli P, Solimena M, Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxyl, Journal of Biological Chemistry, 270(5), 2241-6, 3 Feb 1995
• Lernmark A, Glutamic acid decarboxylase antibodies and diabetes complications. Assay reliability and validity, Diabetes Care, 18(2), 269-71, February 1995
• Sanjeevi C B, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark A, Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus, Tissue Antigens, 45(2), 148-52, February 1995
• Gottsater A, Landin-Olsson M, Lernmark A, Fernlund P, Sundkvist G, Hagopian W A, Glutamate decarboxylase antibody levels predict rate of beta-cell decline in adult-onset diabetes, Diabetes Research and Clinical Practice, 27(2), 133-40, February 1995
• Sanjeevi C B, Lybrand T P, DeWeese C, Landin-Olsson M, Kockum I, Dahlquist G, Sundkvist G, Stenger D, Lernmark A, Polymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurrence of IDDM. Members of the Swedish Childhood Diabetes Study, Diabetes, 44(1), 125-31, January 1995
• Li L, Jiang J, Hagopian W A, Karlsen A E, Skelly M, Baskin D G, Lernmark A, Differential detection of rat islet and brain glutamic acid decarboxylase (GAD) isoforms with sequence-specific peptide antibodies, Journal of Histochemistry and Cytochemistry, 43(1), 53-9, January 1995
• Jacob H J, Brown D M, Bunker R K, Daly M J, Dzau V J, Goodman A, Koike G, Kren V, Kurtz T, Lernmark A, et al, A genetic linkage map of the laboratory rat, Rattus norvegicus, Nature Genetics, 9(1), 63-9, January 1995
• Falorni A, Kockum I, Sanjeevi C B, Lernmark A, Pathogenesis of insulin-dependent diabetes mellitus, Baillieres Clinical Endocrinology and Metabolism, 9(1), 25-46, January 1995
• Pollema C H, Lernmark A, Ruzicka J, Flow injection fluorescence microscopy applied to a rapid cell surface immunoassay, Cytometry, 19(1), 70-6, 1 Jan 1995
• Lernmark A, Kloppel G, Stenger D, Vathanaprida C, Falt K, Landin-Olsson M, Baskin D G, Palmer J P, Gown A M, Petersen J S, et al, Heterogeneity of islet pathology in two infants with recent onset diabetes mellitus, Virchows Archives, 425(6), 631-40, 1995
• Gold D P, Shaikewitz S T, Mueller D, Redd J R, Sellins K S, Pettersson A, Lernmark A, Bellgrau D, T cells from BB-DP rats show a unique cytokine mRNA profile associated with the IDDM1 susceptibility gene, Lyp, Autoimmunity, 22(3), 149-61, 1995
• Gottsater A, Landin-Olsson M, Lernmark A, Fernlund P, Sundkvist G, Islet cell antibodies are associated with beta-cell failure also in obese adult onset diabetic patients, Acta Diabetologica, 31(4), 226-31, December 1994
• Lernmark A, Can insulin-dependent diabetes be cured? More research on GAD autoimmunity is necessary, Lakartidningen, 91(44), 3977-80, 2 Nov 1994
• Kockum I, Wassmuth R, Holmberg E, Michelsen B, Lernmark A, Inheritance of MHC class II genes in IDDM studied in population-based affected and control families, Diabetologia, 37(11), 1105-12, November 1994
• Hao W, Li L, Mehta V, Lernmark A, Palmer J P, Functional state of the beta cell affects expression of both forms of glutamic acid decarboxylase, Pancreas, 9(5), 558-62, September 1994
• Lernmark A, Molecular biology of IDDM, Diabetologia, 37 Suppl 2, S73-81, September 1994
• Sanjeevi C B, Lybrand T P, Landin-Olsson M, Kockum I, Dahlquist G, Hagopian W A, Palmer J P, Lernmark A, Analysis of antibody markers, DRB1, DRB5, DQA1 and DQB1 genes and modeling of DR2 molecules in DR2-positive patients with insulin-dependent diabetes mellitus, Tissue Antigens, 44(2), 110-9, August 1994
• Sundkvist G, Hagopian W A, Landin-Olsson M, Lernmark A, Ohlsson L, Ericsson C, Ahlmen J, Islet cell antibodies, but not glutamic acid decarboxylase antibodies, are decreased by plasmapheresis in patients with newly diagnosed insulin-dependent diabetes mellitus, Journal of Clinical Endocrinology and Metabolism, 78(5), 1159-65, May 1994
• Grubin C E, Daniels T, Toivola B, Landin-Olsson M, Hagopian W A, Li L, Karlsen A E, Boel E, Michelsen B, Lernmark A, A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM, Diabetologia, 37(4), 344-50, April 1994
• Buesa-Gomez J, de la Torre J C, Dyrberg T, Landin-Olsson M, Mauseth R S, Lernmark A, Oldstone M B, Failure to detect genomic viral sequences in pancreatic tissues from two children with acute-onset diabetes mellitus, Journal of Medical Virology, 42(2), 193-7, February 1994
• Li L, Hagopian W A, Brashear H R, Daniels T, Lernmark A, Identification of autoantibody epitopes of glutamic acid decarboxylase in stiff-man syndrome patients, Journal of Immunology, 152(2), 930-4, 15 Jan 1994
• Richardson R D, Ramsay D S, Lernmark A, Scheurink A J, Baskin D G, Woods S C, Weight loss in rats following intraventricular transplants of pancreatic islets, American Journal of Physiology, 266(1 Pt 2), R59-64, January 1994
• Lernmark A, Ostman J, [Diabetes mellitus type 1 with onset between ages 15-34 years. Report of current status from the study of diabetes incidence in Sweden], Lakartidningen, 90(42), 3652-6, 20 Oct 1993
• Haag F, Nolte F, Lernmark A, Simrell C, Thiele H G, Analysis of T-cell surface marker profiles during the postnatal ontogeny of normal and diabetes-prone rats, Transplantation Proceedings, 25(5), 2831-2, October 1993
• Lernmark A, Moller C, Kockum I, Sanjeevi C, Islet cell autoimmunity, Journal of Internal Medicine, 234(4), 361-9, October 1993
• Kockum I, Wassmuth R, Holmberg E, Michelsen B, Lernmark A, HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls, American Journal of Human Genetics, 53(1), 150-67, July 1993
• Edelhoff S, Grubin C E, Karlsen A E, Alder D A, Foster D, Disteche C M, Lernmark A, Mapping of glutamic acid decarboxylase (GAD) genes, Genomics, 17(1), 93-7, July 1993
• Markholst H, Eastman S, Wilson D, Fisher L, Lernmark A, Decreased weight gain in BB rats before the clinical onset of insulin-dependent diabetes, Diabetes Research and Clinical Practice, 21(1), 31-8, July 1993
• Hagopian W A, Karlsen A E, Petersen J S, Teague J, Gervassi A, Jiang J, Fujimoto W, Lernmark A, Regulation of glutamic acid decarboxylase diabetes autoantigen expression in highly purified isolated islets from Macaca nemestrina, Endocrinology, 132(6), 2674-81, June 1993
• Gottsater A, Landin-Olsson M, Fernlund P, Lernmark A, Sundkvist G, Beta-cell function in relation to islet cell antibodies during the first 3 yr after clinical diagnosis of diabetes in type II diabetic patients, Diabetes Care, 16(6), 902-10, June 1993
• Hagopian W A, Michelsen B, Karlsen A E, Larsen F, Moody A, Grubin C E, Rowe R, Petersen J, McEvoy R, Lernmark A, Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase, Diabetes, 42(4), 631-6, April 1993
• Neifing J L, Greenbaum C J, Kahn S E, McCulloch D K, Barmeier H, Lernmark A, Palmer J P, Prospective evaluation of beta-cell function in insulin autoantibody-positive relatives of insulin-dependent diabetic patients, Metabolism: Clinical and Experimental, 42(4), 482-6, April 1993
• Ivarsson S A, Eriksson S, Kockum I, Lernmark A, Lindgren S, Nilsson K O, Sundkvist G, Wassmuth R, HLA-DR3, DQ2 homozygosity in two patients with insulin-dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis, Journal of Internal Medicine, 233(3), 281-6, March 1993
• Hagopian W A, Karlsen A E, Gottsater A, Landin-Olsson M, Grubin C E, Sundkvist G, Petersen J S, Boel E, Dyrberg T, Lernmark A, Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type, Journal of Clinical Investigation, 91(1), 368-74, January 1993
• Jobe L W, Ubungen R, Goodner C J, Baskin D G, Braquet P, Lernmark A, Protection from BB rat diabetes by the platelet-activating factor inhibitor BN50730, Autoimmunity, 16(4), 259-66, 1993
• Greenbaum C J, Palmer J P, Nagataki S, Yamaguchi Y, Molenaar J L, Van Beers W A, MacLaren N K, Lernmark A, Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop, Diabetes, 41(12), 1570-4, December 1992
• Lernmark A, Morris P J, Rubenstein A H, Diabetes and frontiers of research. Introduction, Diabetologia, 35 Suppl 2, A9-11, December 1992
• Lernmark A, Immune intervention yes, but for what reason, for whom, when and how?, Diabetologia, 35(11), 1096-8, November 1992
• Gottsater A, Landin-Olsson M, Fernlund P, Gullberg B, Lernmark A, Sundkvist G, Pancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and C-peptide to measure insulin secretion, Scandinavian Journal of Clinical and Laboratory Investigation, 52(7), 631-9, November 1992
• Landin-Olsson M, Palmer J P, Lernmark A, Blom L, Sundkvist G, Nystrom L, Dahlquist G, Predictive value of islet cell and insulin autoantibodies for type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children, Diabetologia, 35(11), 1068-73, November 1992
• Karlsen A E, Hagopian W A, Petersen J S, Boel E, Dyrberg T, Grubin C E, Michelsen B K, Madsen O D, Lernmark A, Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies, Diabetes, 41(10), 1355-9, October 1992
• Jacob H J, Pettersson A, Wilson D, Mao Y, Lernmark A, Lander E S, Genetic dissection of autoimmune type I diabetes in the BB rat [published erratum appears in Nat Genet 1994 Jun;7(2):215], Nature Genetics, 2(1), 56-60, September 1992
• Landin-Olsson M, Karlsson F A, Lernmark A, Sundkvist G, Islet cell and thyrogastric antibodies in 633 consecutive 15- to 34-yr-old patients in the diabetes incidence study in Sweden, Diabetes, 41(8), 1022-7, August 1992
• Pollema C H, Ruzicka J, Christian G D, Lernmark A, Sequential injection immunoassay utilizing immunomagnetic beads, Analytical Chemistry, 64(13), 1356-61, 1 Jul 1992
• Jobe L W, Vertrees S, Wilson C A, Jacobs C, Wilson D L, Picha K S, Baker P, Lernmark A, In vivo effects of interleukin-1 beta on blood leukocytes in BB rats prone or resistant to diabetes, Autoimmunity, 11(4), 233-7, 1992
• Barmeier H, Ahlmen J, Landin-Olsson M, Rajotte R V, Sundkvist G, Warnock G, Lernmark A, Quantitative analysis of islet glutamic acid decarboxylase p64 autoantibodies in insulin-dependent diabetes mellitus, Autoimmunity, 13(3), 187-96, 1992
• Marner B, Bille G, Christy M, Damsgaard E M, Garne S, Heinze E, Larsen S, Lernmark A, Mandrup-Poulsen T, Nerup J, et al, Islet cell cytoplasmic antibodies (ICA) in diabetes and disorders of glucose tolerance, Diabetic Medicine, 8(9), 812-6, November 1991
• Barmeier H, McCulloch D K, Neifing J L, Warnock G, Rajotte R V, Palmer J P, Lernmark A, Risk for developing type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies, Diabetologia, 34(10), 727-33, October 1991
• Sundkvist G, Bergqvist A, Weibull H, Bergqvist D, Falt K, Olsson M L, Lernmark A, Islet cell antibody reactivity with human fetal pancreatic islets, Diabetes Research and Clinical Practice, 14(1), 1-7, October 1991
• Vertrees S, Wilson C A, Ubungen R, Wilson D, Baskin D G, Toivola B, Jacobs C, Boiani N, Baker P, Lernmark A, Interleukin-1 beta regulation of islet and thyroid autoimmunity in the BB rat, Journal of Autoimmunity, 4(5), 717-32, October 1991
• Lernmark A, Barmeier H, Dube S, Hagopian W, Karlsen A, Wassmuth R, Autoimmunity of diabetes, Endocrinology and Metabolism Clinics of North America, 20(3), 589-617, September 1991
• Markholst H, Eastman S, Wilson D, Andreasen B E, Lernmark A, Diabetes segregates as a single locus in crosses between inbred BB rats prone or resistant to diabetes, Journal of Experimental Medicine, 174(1), 297-300, 1 Jul 1991
• Lernmark A, Molenaar J L, van Beers W A, Yamaguchi Y, Nagataki S, Ludvigsson J, Maclaren N K, The Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies. The Immunology and Diabetes Workshops and Participating Laboratories, Diabetologia, 34(7), 534-5, July 1991
• Eastman S, Markholst H, Wilson D, Lernmark A, Leukocytosis at the onset of diabetes in crosses of inbred BB rats, Diabetes Research and Clinical Practice, 12(2), 113-23, May 1991
• Karlsen A E, Fujimoto W Y, Rabinovitch P, Dube S, Lernmark A, Effects of sodium butyrate on proliferation-dependent insulin gene expression and insulin release in glucose-sensitive RIN-5AH cells, Journal of Biological Chemistry, 266(12), 7542-8, 25 Apr 1991
• Beck J C, Goodner C J, Wilson C, Wilson D, Glidden D, Baskin D G, Lernmark A, Braquet P, Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat, Autoimmunity, 9(3), 225-35, 1991
• Lernmark A, Human cell lines from families available for diabetes research, Diabetologia, 34(1), 61, January 1991
• Lernmark A, Ducat L, Eisenbarth G, Ott J, Permutt M A, Rubenstein P, Spielman R, Family cell lines available for research, American Journal of Human Genetics, 47(6), 1028-30, December 1990
• Lernmark A, Barmeier H, Dube S, Hagopian W, Karlsen A E, Markholst H, Wilson C, Wassmuth R, Molecular analysis of the pathogenesis of beta-cell destruction in insulin-dependent diabetes mellitus, Western Journal of Medicine, 153(5), 499-502, November 1990
• Kuglin B, Kolb H, Greenbaum C, Maclaren N K, Lernmark A, Palmer J P, The Fourth International Workshop on the Standardisation of Insulin Autoantibody Workshop, Diabetologia, 33(10), 638-9, October 1990
• Landin-Olsson M, Nilsson K O, Lernmark A, Sundkvist G, Islet cell antibodies and fasting C-peptide predict insulin requirement at diagnosis of diabetes mellitus, Diabetologia, 33(9), 561-8, September 1990
• Markholst H, Klaff L J, Kloppel G, Lernmark A, Mordes J P, Palmer J, Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats, Diabetes, 39(6), 720-7, June 1990
• Wilson C A, Jacobs C, Baker P, Baskin D G, Dower S, Lernmark A, Toivola B, Vertrees S, Wilson D, IL-1 beta modulation of spontaneous autoimmune diabetes and thyroiditis in the BB rat, Journal of Immunology, 144(10), 3784-8, 15 May 1990
• Landin-Olsson M, Borgstrom A, Blom L, Sundkvist G, Lernmark A, Immunoreactive trypsin(ogen) in the sera of children with recent-onset insulin-dependent diabetes and matched controls. The Swedish Childhood Diabetes Group, Pancreas, 5(3), 241-7, May 1990
• Karlsen A, Lernmark A, Kofod H, Dyrberg T, A novel affinity purification method to isolate peptide specific antibodies, Journal of Immunological Methods, 128(2), 151-7, 17 Apr 1990
• Michelsen B, Wassmuth R, Ludvigsson J, Lernmark A, Nepom G T, Fisher L, HLA heterozygosity in insulin-dependent diabetes is most frequent at the DQ locus, Scandinavian Journal of Immunology, 31(4), 405-13, April 1990
• Christie M R, Pipeleers D G, Lernmark A, Baekkeskov S, Cellular and subcellular localization of an Mr 64,000 protein autoantigen in insulin-dependent diabetes, Journal of Biological Chemistry, 265(1), 376-81, 5 Jan 1990
• Matsuba I, Lernmark A, A novel microwell indirect immunofluorescence assay to detect antibodies against islet cell surface antigens in insulin-dependent diabetes mellitus, Regional Immunology, 3(1), 23-8, Winter 1990
• Michelsen B, Dyrberg T, Vissing H, Serup P, Lernmark A, HLA-DQ and -DX genes in insulin-dependent diabetes mellitus, Current Topics In Microbiology and Immunology, 164, 57-68, 1990
• Bonnevie-Nielsen V, Larsen M L, Frifelt J J, Michelsen B, Lernmark A, Association of IDDM and attenuated response of 2',5'-oligoadenylate synthetase to yellow fever vaccine, Diabetes, 38(12), 1636-42, December 1989
• Landin-Olsson M, Karlsson A, Dahlquist G, Blom L, Lernmark A, Sundkvist G, Islet cell and other organ-specific autoantibodies in all children developing type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched control children, Diabetologia, 32(6), 387-95, June 1989
• Hansen W A, Christie M R, Kahn R, Norgaard A, Abel I, Petersen A M, Jorgensen D W, Baekkeskov S, Nielsen J H, Lernmark A, et al, Supravital dithizone staining in the isolation of human and rat pancreatic islets, Diabetes Research, 10(2), 53-7, February 1989
• Lohr M, Markholst H, Dyrberg T, Kloppel G, Oberholzer M, Lernmark A, Insulitis and diabetes are preceded by a decrease in beta cell volume in diabetes-prone BB rats, Pancreas, 4(1), 95-100, 1989
• Herold K C, Kastern W, Markholst H, Lernmark A, Derivation of non-lymphopenic BB rats with an intercross breeding, Autoimmunity, 3(2), 83-93, 1989
• Michelsen B, Baekkeskov S, Deufel T, Kastern W, Kofod H, Lernmark A, Vissing H, Mechanism and genetic control of the autoimmune response directed against beta-pancreatic cells in insulin-dependent diabetes, Journees Annuelles De Diabetologie De L Hotel-dieu, 171-82, 1985
• Stromberg S, Crock P, Lernmark A, Hulting AL, Pituitary autoantibodies in patients with hypopituitarism and their relatives, Journal of Endocrinology, 157(3), 475-80
• Schranz DB, Lernmark A, Immunology in diabetes: an update, Diabetes/metabolism Reviews, 14(1), 3-29
• Lernmark A, Ott J, Sometimes it's hot, sometimes it's not, Nature Genetics, 19(3), 213-4
• Clark L, Greenbaum C, Jiang J, Lernmark Å and Och H., The antibody response to bacteriophage i linked to the lymphopenia gene in congenic BioBreeding rats, FEMS, 32, 205-209