Dr. Martin William McIntosh

powered by
COS Expertise®
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Molecular Diagnostics
Public Health Sciences
Full MemberAppointed: 2007
Professional Headshot of Martin William McIntosh

Mailing Address

1100 Fairview Ave. North, M2-B230
P.O. Box 19024
Seattle, Washington 98109
United States

Contact Information

Phone: (206) 667-4612
Fax: (206) 667-7264
mmcintosh@fhcrc.org

Qualifications

Ph.D., Harvard University, Statistics, 1998.
A.M., Harvard University, Statistics, 1992.
B.S., Michigan State University, Computer Science & Math, 1986.

Expertise and Research Interests

Tumor biomarker research
Proteomics
Microarray analysis
Cancer screening
Cancer genetics

Keywords

COS Keywords:

Biostatistics, Cancer or Carcinogenesis.

Additional Terms:

Proteomics.

Publications

  • Fitzgibbon M, Li Q, McIntosh M (Jan 2008) Modes of inference for evaluating the confidence of peptide identifications., Journal of proteome research, 7 (1), 35-9 Abstract
  • Loch CM (2007) Use of High Density Antibody Arrays to Validate and Discover Cancer Serum Biomarkers, Molecular Oncology, 1 (3), 313-320
  • McIntosh M (2007) Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma, Clinical Cancer Research, 13 (15(pt 1)), 4422-4428
  • May D, Fitzgibbon M, Liu Y, Holzman T, Eng J, Kemp CJ, Whiteaker J, Paulovich A, McIntosh M (Jul 2007) A platform for accurate mass and time analyses of mass spectrometry data., Journal of proteome research, 6 (7), 2685-94 Abstract
  • Goodell, V, Salazar LG, Urban N, Drescher CW, Gray H, Swensen RE, McIntosh MW, Disis ML (2006) Antibody Immunity to the p53 Oncogenic Protein Is a Prognostic Indicator in Ovarian Cancer, Journal of Clinical Oncology, 24 (5), 762-8
  • Adam Rauch, Matthew Bellew, Jimmy Eng, Matthew Fitzgibbon, Ted Holzman, Peter Hussey, Mark Igra, Brendan Maclean, ChenWei Lin, Andrea Detter, Ruihua Fang, Vitor Faca, Phil Gafken, Heidi Zhang, Jeffrey Whitaker, David States, Sam Hanash, Amanda Paulovich, Martin W. McIntosh (2006) Computational Proteomics Analysis System (CPAS): An extensible open source analytic system for evaluating and publishing proteomic data and high throughput biological experiments, Journal of Proteome Research, 5 (1), 112-21
  • Wang P, Tang H, Zhang H, Whiteaker J, Paulovich AG, McIntosh M (2006) Normalization regarding non-random missing values in high-throughput mass spectrometry data, Proceedings of the Pacific Symposium on Biocomputing, 11, 315-326
  • McIntosh MW (2005) Could high plasma bikunin predict a favorable outcome in ovarian cancer?, Nature Clinical Practice Oncology, 2 (10), 502-503
  • Qinghua Feng, Akhila Balasubramanian, Stephen Hawes, Papa Toure, Papa Salif Sow, Amadou Dem, Birama Dembele, Cathy Critchlow, Long Fu Xi, Hiep Lu, Martin W McIntosh, Alicia M Young, Nancy Kiviat (2003) Detection of Hypermethylated Genes in Biopsies and Exfoliated Cell Samples in Women with and without Cervical Neoplasia and Cervical Cancer, Journal of the National Cancer Institute, 97 (4), 273-82
  • Sow PS, Hawes SE, Critchlow CW, McIntosh MW, Diop A, Diouf MB, Gottlieb GS, Starling AK, Coll-Seck AM, Kiviat NB (2005) Characteristics and presenting complaints of outpatients with undiagnosed HIV infection: potential utility for triage to HIV testing, Characteristics and Presenting Complaints of Outpatients With Undiagnosed HIV Infection: Potential Utility in Selecting S, Journal Acquire Immune Deficiency Syndrome, 37 (4), 1520-1528
  • McIntosh MW, Drescher C, Urban N, Hellstrom KE, Hellstrom I (2004) Combining CA125 and SMR serum markers for diagnosis and early detection of ovarian carcinoma, Gynecol Oncology, 95 (1), 9-15
  • Urban N, McIntosh MW, Andersen MR, Karlan BY (2003) Ovarian cancer screening, Hematology/Oncology Clinics of North America, 17 (4), 989-1005, ix
  • Hellstrom I, Raycraft J, Ledbetter M, Ledbetter J, Schummer M, McIntosh MW, Drescher C, Urban N, Hellstrom KE (2003) The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma, Cancer Research, 63 (13), 3695-3700
  • Etzioni R, Urban N, Ramsey S, McIntosh M, Schwartz S, Reid B, Radich J, Anderson G, Hartwell L (2003) The case for early detection, Nature Reviews Cancer, 3 (4), 243-252
  • Bogusky M, McIntosh MW (2003) Biomedical informatics for proteomics, Nature, 422 (6928), 233-237
  • McIntosh, MW, Urban, N, A Parametric Empirical Bayes Method for Cancer Screening using Longitudinal Observations of a Biomarker, Biostatistics, 3(3), December 2002
  • McIntosh MW, Pepe MS, Combining several screening tests: optimality of the risk score, Biometrics, 58(3), 657-64, September 2002
  • McIntosh MW, Urban N, Karlan B, Generating longitudinal screening algorithms using novel biomarkers for disease, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 11(2), 159-66, February 2002 Abstract
  • Martin W McIntosh, Ramsey S, Berry K, Urban N., Solicitation and Estimation for Cost Effectivness Studies, Health Economics, 10(1), Jan 2001
  • McIntosh M.W., Instrumental variables when evaluating screening trials: estimating the benefit of detecting cancer by screening, Statistics in Medicine, 18(20), 2775-94, October 1999 Abstract
  • McIntosh M.W, Rubin D.B., On estimating the causal effects of DNR orders [editorial, Medical Care, 37(8), 722-6, August 1999 Abstract
  • Schmid CH, Lau J, McIntosh MW, Cappelleri JC, An empirical study of the effect of the control rate as a predictor of treatment efficacy in meta-analysis of clinical trials, Statistics in Medicine, 17(17), 1923-42, September 1998 Abstract
  • Zucker DR, Schmid CH, McIntosh MW, D'Agostino RB, Selker HP, Lau J, Combining single patient (N-of-1) trials to estimate population treatment effects and to evaluate individual patient responses to treatment, Journal of Clinical Epidemiology, 50(4), 401-10, April 1997 Abstract
  • McIntosh M.W., The population risk as an explanatory variable in research synthesis of clinical trials, Statistics in Medicine, 15(16), 1713-28, August 1996 Abstract

Profile Details

Last Verified: 4/9/2008

COS Expertise ID #102383
Reference this profile directly: http://myprofile.cos.com/mcmart