Anne McTiernan

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Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Cancer Prevention
Full Member
University of Washington
Epidemiology and Geriatrics
Research Professor
Professional Headshot of Anne  McTiernan

Mailing Address

Fred Hutchinson Cancer Research Center, M4-B402
1100 Fairview Ave. N.
Seattle, Washington 98109-1024
United States

Contact Information

Fax: (206) 667-7850
amctiern@fhcrc.org

Qualifications

Residency Training, University of Washington, Internal Medicine, 1992.
M.D., New York Medical College, 1989.
Ph.D., University of Washington, Epidemiology, 1982.

Expertise and Research Interests

Dr. McTiernan's research focuses on identifying ways to prevent new or recurrent cancer with a particular focus on weight control, physical activity, and chemoprevention. She is Principal Investigator of the Seattle TREC Center investigating mechanisms of energy balance and cancer prevention. She leads over twenty five scientists in transdisciplinary reasearch to elucidate the pathways linking components of energy balance to the cancer process. The five projects and four cores incorporate several different study designs, with contributions of scientists from medicine, cell biology, animal models, immunology, biostatistics, mathematics, exercise physiology, and behavioral science.

Dr. McTiernan is also Principal Investigator of a randomized controlled clinical trial of a one-year aerobic exercise intervention to compare the effects over one year of two lifestyle interventions in 503 postmenopausal women: (1) a moderate-intensity aerobic exercise intervention, and (2) a reduced-calorie diet plus moderate-intensity aerobic exercise intervention. She is Principal Investigator of the Seattle site of Health, Eating, Activity, and Lifestyle (HEAL) Study, which is assessing associations among anthropometrics, fat mass amount and distribution, endogenous sex and metabolic hormones, diet, and physical activity on prognostic factors in breast cancer patients. Dr. McTiernan is Principal Investigator of the Seattle site of the ExCel trial which is testing the effect of exemestane, an aromatase inhibitor, on breast cancer prevention, and she leads a randomized clinical trial testing aspirin effect on breast cancer biomarkers.

Previously she has conducted a randomized controlled clinical trial of a one-year aerobic exercise intervention vs. stretch control in 173 postmenopausal women. The primary aim of this study was to assess the effect of exercise on endogenous sex hormones that have been associated with increased risk for breast cancer. Ongoing ancillary studies test the effect of aerobic exercise on immune function and other biomarkers of breast cancer risk.

She is also been Principal Investigator of a randomized clinical trial to test the effect of a one-year aerobic exercise intervention vs. control on colorectal cell proliferation, apoptosis, and prostaglandin content, and on other biomarkers of colon cancer risk in 200 men and women with adenomatous colon polyps.

Dr. McTiernan was a co-Investigator in the Women's Health Initiative (WHI), and directed clinical outcomes efforts at the WHI Clinical Coordinating Center. She has conducted an analysis of physical activity and breast cancer incidence in the WHI Observational Study cohort of over 90,000 women and has collaborated on many additional analyses.

Other Expertise

I have considerable experience with recruitment, retention, adherence, and endpoints in large-scale medication clinical trials (e.g. the Women's Health Initiative hormone therapy and calcium/vitamin D trials). I have expertise in Women's Health issues. Iam co-investigator of the Seattle STAR trial, hence have experience with clinical trials using SERMS.

Keywords

COS Keywords:

Biomarkers, Breast Cancer, Clinical Trial, Hormones, Rehabilitation or Therapy.

Memberships

American College of Epidemiology
American Society of Preventive Oncology
Society for Epidemiologic Research

Publications

  • Mustian KM, Griggs J, Morrow GR, McTiernan A, Roscoe JA, Atkins JN, Issel B (2006) Exercise and Side Effects Among 749 Patients During and After Treatment for Cancer: A University of Rochester Cancer Center Communtity Clinical Oncology Program Study, Supportive Care in Cancer
  • Alfano CM, McGregor BA, Kuniyuki A, Reeve BB, Bowen DJ, Baumgartner KB (2006) Psychometric Properties of a Tool for Measuring Hormone-Related Symptoms in Breast Cancer Survivors, Psycho-Oncology
  • Troen AM, Mitchell B, Sorenson B, Wener MH, Johnston A, Wood B, Selhub J, McTiernan A, Yasui Y, Potter JD, Ulrich CM (2006) Unmetabolized Folic Acid in Plasma is Associated with Reduced Natural Killer Cell Cytotoxicity Among Postmenopausal Women, The Journal of Nutrition, 136(1) (189), 194
  • Frakenfeld CL, McTiernan A, Schramm JK, Yasui Y, McVarish L, Ulrich CM, Thomas WK, Lampe JW (2006) Bone Mineral Density in Relation to Soy Isoflavone-Metabolizing Phenotypes in 92 Postmenopausal Women, Maturitas, 53 (315), 324
  • Mohanka MR, Heckbert SR, Yasui Y, Sorenson B, Chubak J, Tworoger SS, Ulrich CM, McTiernan A (2006) A Randomized Trial: No Evidence of Change in Blood Lipids in Overweight Postmenopausal Women After 1-Year Moderate Intensity Exercise, Medicine and Science in Sports and Medicine, 38(2) (231), 9
  • Irwin ML, Aiello E, McTiernan A, Baumgartner R, Baumgartner KB, Berstein L, Gilliland F, Ballard-Barbash R (2006) Pre-Diagnosis Physical Activity and Mammographic Density in Breat Cancer Survivors, Breast Cancer Research and Treatment, 95(2) (171), 8
  • Alfano CM, McGregor BA, Kuniyuki A, Reeve B, Bowen DJ, Smith AW, Baumgartner K, Bernstein L, Ballard-Barbash R, Malone K, Ganz P, McTiernan A (2006) Psychometric Evaluation of the Brief Cancer Impact Assessment Among Breast Cancer Survivors, Oncology, 70 (190), 202
  • Ronseberg C, Khandekar J, Greenberg P, Rodabough RJ, McTiernan A (2006) Occurrence of Melanoma Following Nonmelanoma Skin Cancer - A Prospective Observational Study from the Women's Health Initiative, Cancer, 106(3) (654), 663
  • Cauley J (2006) HMG Co-A Reductase Inhibitor (Statin) Use and Risk of Breast Cancer in the Women's Health Initiative Observational Study, JNCI, 98 (700), 7
  • Irwin ML (2005) The Association Between Physical Activity Levels and Mammographic Breast Density in Pre- and Post-Menopausal Women: The Health, Eating, Activity, and Lifestyle (HEAL) Study, Breast Cancer Research and Treatment
  • Aiello EJ, Tworoger SS, Yasui Y, Stanczyk FZ, Potter J, Ulrich CM, Irwin M, McTiernan A (Jun 2005) Associations among circulating sex hormones, insulin-like growth factor, lipids, and mammographic density in postmenopausal women., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 14 (6), 1411-7 Abstract
  • McTiernan A (Jun 2005) Obesity and cancer: the risks, science, and potential management strategies., Oncology (williston Park, N.y.), 19 (7), 871-81; discussion 8 Abstract
  • McTiernan A, Sorensen B, Yasui Y, Tworoger SS, Ulrich CM, Irwin ML, Rudolph RE, Stanczyk FZ, Schwartz RS, Potter JD (2005) No Effect of Exercise on Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3 in Postmenopausal Women: a 12-Month Randomized Clinical Trial, CEBP, 14 (4), 1020-1
  • Frank LL, Sorensen BE, Yasui Y, Tworoger SS, Schwartz RS, Ulrich CM, Irwin ML, Rudolph RE, Rajan KB, Stanczyk F, Bowen D, Weigle DS, Potter JD, McTiernan A (Mar 2005) Effects of exercise on metabolic risk variables in overweight postmenopausal women: a randomized clinical trial., Obesity Research, 13 (3), 615-25 Abstract
  • Chlebowski RT, Chen Z, Anderson GL, Rohan T, Aragaki A, Lane D, Dolan NC, Paskett ED, McTiernan A, Hubbell FA, Adams-Campbell LL, Prentice R (Mar 2005) Ethnicity and breast cancer: factors influencing differences in incidence and outcome., Journal of the National Cancer Institute, 97 (6), 439-48 Abstract
  • Frank LL, Sorensen BE, Yasui Y, Tworoger SS, Schwartz RS, Ulrich CM, Irwin ML, Rudolph RE, Rajan KB, Stanczyk F, Bowen D, Weigle DS, Potter JD, McTiernan A (Mar 2005) Effects of exercise on metabolic risk variables in overweight postmenopausal women: a randomized clinical trial., Obesity Research, 13 (3), 615-25 Abstract
  • Foster-Schubert KE, McTiernan A, Frayo RS, Schwartz RS, Rajan KB, Yasui Y, Tworoger SS, Cummings DE (Feb 2005) Human plasma ghrelin levels increase during a one-year exercise program., The Journal of Clinical Endocrinology and Metabolism, 90 (2), 820-5 Abstract
  • Irwin ML, McTiernan A, Baumgartner RN, Baumgartner KB, Bernstein L, Gilliland FD, Ballard-Barbash R (Feb 2005) Changes in body fat and weight after a breast cancer diagnosis: influence of demographic, prognostic, and lifestyle factors., Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 23 (4), 774-82 Abstract
  • Foster-Schubert KE, McTiernan A, Frayo RS, Schwartz RS, Rajan KB, Yasui Y, Tworoger SS, Cummings DE (Feb 2005) Human plasma ghrelin levels increase during a one-year exercise program., The Journal of Clinical Endocrinology and Metabolism, 90 (2), 820-5 Abstract
  • Irwin M (2005) Relationship of Obesity and Physical with C-Peptide, Leptin, and Insulin-Like Growth Factors in Breast Cancer Survivors, CEBP
  • Chubak J, Tworoger SS, Yasui Y, Ulrich CM, McTiernan A (2005) Associations Between Reproductive and Menstrual Factors and Postmenopausal Androgen Concentrations, J Women's Health (Larchmt), 14 (704), 12
  • Tworoger SS, Davis S, Vitiello MV, Lentz MJ, McTiernan A (2005) Factors associated with objective (actigraphic) and subjective sleep quality in young adult women, J Psychosomatic Res., 59, 11-19
  • McTiernan A, Martin C, Peck JD, Aragaki A, Chlebowski R, Pisano E, Wang CY, Brunner R, Johnson KC, Manson JE, Lewis CE, Kotchen JM, Hulka B, for the Women's Health Initiative Mammogram Density Study Investigators (2005) Estrogen Plus Progestin Influence on Mammogram Density in Healthy Postmenopausal Women in the Women's Health Initiative Randomized Trial, Journal National Cancer Institute, 97, 1366-1376
  • McTiernan A. (2005) Cancer Prevention and Management Through Exercise and Weight Control, CRC Press
  • Alfano CM, Klesges RC, Murray DM, Bowen DJ, McTiernan A, Vander Weg MW, Robinson LA, Cartmel B, Thornquist MD, Barnett M, Goodman GE, Omenn GS (Dec 2004) Physical activity in relation to all-site and lung cancer incidence and mortality in current and former smokers., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13 (12), 2233-41 Abstract
  • Prentice RL, Willett WC, Greenwald P, Alberts D, Bernstein L, Boyd NF, Byers T, Clinton SK, Fraser G, Freedman L, Hunter D, Kipnis V, Kolonel LN, Kristal BS, Kristal A, Lampe JW, McTiernan A, Milner J, Patterson RE, Potter JD, Riboli E, Schatzkin A, Yates A, Yetley E (Sep 2004) Nutrition and physical activity and chronic disease prevention: research strategies and recommendations., Journal of the National Cancer Institute, 96 (17), 1276-87 Abstract
  • Tworoger SS, Davis S, Emerson SS, Mirick DK, Lentz MJ, McTiernan A, Effect of a nighttime magnetic field exposure on sleep patterns in young women, American Journal of Epidemiology, 160(3), 224-9, August 2004 Abstract
  • Chubak J, Tworoger SS, Yasui Y, Ulrich CM, Stanczyk FZ, McTiernan A (Aug 2004) Associations between reproductive and menstrual factors and postmenopausal sex hormone concentrations., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13 (8), 1296-301 Abstract
  • Tworoger SS, Davis S, Emerson SS, Mirick DK, Lentz MJ, McTiernan A (Aug 2004) Effect of a nighttime magnetic field exposure on sleep patterns in young women., American Journal of Epidemiology, 160 (3), 224-9 Abstract
  • McGregor BA, Bowen DJ, Ankerst DP, Andersen MR, Yasui Y, McTiernan A (Jul 2004) Optimism, perceived risk of breast cancer, and cancer worry among a community-based sample of women., Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association., 23 (4), 339-44 Abstract
  • Frankenfeld CL, McTiernan A, Aiello EJ, Thomas WK, LaCroix K, Schramm J, Schwartz SM, Holt VL, Lampe JW (Jul 2004) Mammographic density in relation to daidzein-metabolizing phenotypes in overweight, postmenopausal women., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13 (7), 1156-62 Abstract
  • Shade ED, Ulrich CM, Wener MH, Wood B, Yasui Y, Lacroix K, Potter JD, McTiernan A, Frequent intentional weight loss is associated with lower natural killer cell cytotoxicity in postmenopausal women: possible long-term immune effects, Journal of the American Dietetic Association, 104(6), 903-12, June 2004 Abstract
  • Tworoger SS, Chubak J, Aiello EJ, Yasui Y, Ulrich CM, Farin FM, Stapleton PL, Irwin ML, Potter JD, Schwartz RS, McTiernan A (Jun 2004) The effect of CYP19 and COMT polymorphisms on exercise-induced fat loss in postmenopausal women., Obesity Research, 12 (6), 972-81 Abstract
  • Atkinson C, Lampe JW, Tworoger SS, Ulrich CM, Bowen D, Irwin ML, Schwartz RS, Rajan BK, Yasui Y, Potter JD, McTiernan A, Effects of a moderate intensity exercise intervention on estrogen metabolism in postmenopausal women, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13(5), 868-74, May 2004 Abstract
  • Atkinson C, Lampe JW, Tworoger SS, Ulrich CM, Bowen D, Irwin ML, Schwartz RS, Rajan BK, Yasui Y, Potter JD, McTiernan A (May 2004) Effects of a moderate intensity exercise intervention on estrogen metabolism in postmenopausal women., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13 (5), 868-74 Abstract
  • Bowen DJ, Burke W, McTiernan A, Yasui Y, Andersen MR, Breast cancer risk counseling improves women's functioning, Patient Education and Counseling, 53(1), 79-86, April 2004 Abstract
  • McTiernan A, Tworoger SS, Ulrich CM, Yasui Y, Irwin ML, Rajan KB, Sorensen B, Rudolph RE, Bowen D, Stanczyk FZ, Potter JD, Schwartz RS, Effect of exercise on serum estrogens in postmenopausal women: a 12-month randomized clinical trial, Cancer Research, 64(8), 2923-8, April 2004 Abstract
  • Frankenfeld CL, McTiernan A, Tworoger SS, Atkinson C, Thomas WK, Stanczyk FZ, Marcovina SM, Weigle DS, Weiss NS, Holt VL, Schwartz SM, Lampe JW, Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes, The Journal of Steroid Biochemistry and Molecular Biology, 88(4-5), 399-408, April 2004 Abstract
  • McTiernan A, Physical activity after cancer: physiologic outcomes, Cancer Investigation, 22(1), 68-81, 2004 Abstract
  • Tworoger SS, Chubak J, Aiello EJ, Ulrich CM, Atkinson C, Potter JD, Yasui Y, Stapleton PL, Lampe JW, Farin FM, Stanczyk FZ, McTiernan A, Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13(1), 94-101, 2004 Abstract
  • Sparks R, Ulrich CM, Bigler J, Tworoger SS, Yasui Y, Rajan KB, Porter P, Stanczyk FZ, Ballard-Barbash R, Yuan X, Lin MG, McVarish L, Aiello EJ, McTiernan A (2004) UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients., Breast Cancer Research : Bcr, 6 (5), R488-98 Abstract
  • Tworoger SS, Yasui Y, Chang L, Stanczyk FZ, McTiernan A (2004) Specimen Allocation in Longitudinal Biomarker Studies: Controlling Subject -Specific Levels by Design, Cancer, Epidemiology, Biomarkers & Prevention, 13(7) (1257-), 1260
  • Irwin M, McTiernan A, Bernstein L, Baumgartner R, Gilliland FD, Ballard-Barbash R (2004) Physical Activity Levels Across the Breast Cancer Experience: The Health, Eating, Activity, and Lifestyle (HEAL) Study, Medicine and Science in Sports and Exercise, 36(9) (1484), 1491
  • Baumgartner KB, Baumgartner RN, Hunt WC, Crumley DD, Gilliland FD, McTiernan A, Bernstein L, Ballard-Barbash R (2004) Association of Body Composition and Weight History with Breast Cancer Prognostic Markers: a Divergent Pattern Between Hispanic and Non-Hispanic White Women, American Journal of Epidemiology, 22(22) (4507), 13
  • Irwin ML, Tworoger SS, Yasui Y, Rajan K, McVarish L, LaCroix K, Ulrich C, Bowen D, Schwartz RS, Potter J, McTiernan A (2004) Influence of Demographic, Physciologic, and Psychosocial Variables on Adherence to a Yearlong Moderate-Intensity Exercise Trial in Postmenopausal Women, Preventative Medicine, 39 (1080), 86
  • McTiernan A, Intervention studies in exercise and cancer prevention, Medicine and Science in Sports and Exercise, 35(11), 1841-5, 2003 Abstract
  • McTiernan A, Physical activity, exercise, and cancer: prevention to treatment--symposium overview, Medicine and Science in Sports and Exercise, 35(11), 1821-2, 2003 Abstract
  • Tworoger SS, Yasui Y, Vitiello MV, Schwartz RS, Ulrich CM, Aiello EJ, Irwin ML, Bowen D, Potter JD, McTiernan A, Effects of a yearlong moderate-intensity exercise and a stretching intervention on sleep quality in postmenopausal women, Sleep, 26(7), 830-6, 2003 Abstract
  • Andersen MR, Bowen D, Yasui Y, McTiernan A, Awareness and concern about ovarian cancer among women at risk because of a family history of breast or ovarian cancer, American Journal of Obstetrics and Gynecology, 189(4 Suppl), S42-7, 2003 Abstract
  • Mack WJ, Preston-Martin S, Dal Maso L, Galanti R, Xiang M, Franceschi S, Hallquist A, Jin F, Kolonel L, La Vecchia C, Levi F, Linos A, Lund E, McTiernan A, Mabuchi K, Negri E, Wingren G, Ron E (Oct 2003) A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea., Cancer Causes & Control : Ccc, 14 (8), 773-85 Abstract
  • Curb JD, McTiernan A, Heckbert SR, Kooperberg C, Stanford J, Nevitt M, Johnson KC, Proulx-Burns L, Pastore L, Criqui M, Daugherty S, WHI Morbidity and Mortality Committee (Oct 2003) Outcomes ascertainment and adjudication methods in the Women's Health Initiative., Annals of Epidemiology, 13 (9 Suppl), S122-8 Abstract
  • McTiernan A, Issues surrounding the participation of adolescents with cancer in clinical trials in the UK, European Journal of Cancer Care, 12(3), 233-9, 2003 Abstract
  • McTiernan A, Kooperberg C, White E, Wilcox S, Coates R, Adams-Campbell LL, Woods N, Ockene J, Women's Health Initiative Cohort Study, Recreational physical activity and the risk of breast cancer in postmenopausal women: the Women's Health Initiative Cohort Study, Jama : the Journal of the American Medical Association, 290(10), 1331-6, 2003 Abstract
  • Harris RE, Chlebowski RT, Jackson RD, Frid DJ, Ascenseo JL, Anderson G, Loar A, Rodabough RJ, White E, McTiernan A, Women's Health Initiative, Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women's Health Initiative, Cancer Research, 63(18), 6096-101, 2003 Abstract
  • Harris RE, Chlebowski RT, Jackson RD, Frid DJ, Ascenseo JL, Anderson G, Loar A, Rodabough RJ, White E, McTiernan A, Women's Health Initiative (Sep 2003) Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women's Health Initiative., Cancer Research, 63 (18), 6096-101 Abstract
  • McTiernan A, Kooperberg C, White E, Wilcox S, Coates R, Adams-Campbell LL, Woods N, Ockene J, Women's Health Initiative Cohort Study (Sep 2003) Recreational physical activity and the risk of breast cancer in postmenopausal women: the Women's Health Initiative Cohort Study., Jama : the Journal of the American Medical Association, 290 (10), 1331-6 Abstract
  • Strauss SJ, McTiernan A, Driver D, Hall-Craggs M, Sandison A, Cassoni AM, Kilby A, Michelagnoli M, Pringle J, Cobb J, Briggs T, Cannon S, Witt J, Whelan JS (Aug 2003) Single center experience of a new intensive induction therapy for ewing's family of tumors: feasibility, toxicity, and stem cell mobilization properties., Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21 (15), 2974-81 Abstract
  • Chlebowski RT, Hendrix SL, Langer RD, Stefanick ML, Gass M, Lane D, Rodabough RJ, Gilligan MA, Cyr MG, Thomson CA, Khandekar J, Petrovitch H, McTiernan A, WHI Investigators, Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial, Jama : the Journal of the American Medical Association, 289(24), 3243-53, 2003 Abstract
  • McTiernan A, Rajan KB, Tworoger SS, Irwin M, Bernstein L, Baumgartner R, Gilliland F, Stanczyk FZ, Yasui Y, Ballard-Barbash R, Adiposity and sex hormones in postmenopausal breast cancer survivors, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(10), 1961-6, 2003 Abstract
  • Irwin ML, Crumley D, McTiernan A, Bernstein L, Baumgartner R, Gilliland FD, Kriska A, Ballard-Barbash R, Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study, Cancer, 97(7), 1746-57, 2003 Abstract
  • Irwin M, Yasui Y, Bowen D, Rudolph R, Schwartz R, Yukawa M, Aiello E, Potter J, McTiernan A, Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial, Journal of the American Medical Association, 289(3), 323-330, 15 Jan 2003
  • McTiernan A, Behavioral risk factors in breast cancer: can risk be modified?, The Oncologist, 8(4), 326-34, 2003 Abstract
  • Chlebowski RT, McTiernan A, Biological significance of interventions that change breast density, Journal of the National Cancer Institute, 95(1), 4-5, 2003 Abstract
  • Irwin ML, Yasui Y, Ulrich CM, Bowen D, Rudolph RE, Schwartz RS, Yukawa M, Aiello E, Potter JD, McTiernan A, Effect of exercise on total and intra-abdominal body fat in postmenopausal women: a randomized controlled trial, Jama : the Journal of the American Medical Association, 289(3), 323-30, 2003 Abstract
  • LaVecchia C, Brinton LA, McTiernan A, Cancer Risk in Postmenopausal Women, Bailliere's Best Practice and Research. Clinical Obstetrics and Gynaecology, 16(3), 293-307, June 2002
  • Hendrix S, Clark A, Nygaard I, Aragaki A, Barnabei V, McTiernan A, Pelvic organ prolapse in the Women's Health Inititative: Gravity and Gravidity, American Journal of Obstetrics and Gynecology, 186(6), 1160-6, June 2002
  • Tworoger S, Yasui Y, Ulrich C, Nakamura H, LaCroix K, Johnston R, McTiernan A, Mailing Strategies and Recruitment into an Intervention Trial of the Exercise Effect on Breast Cancer Biomarkers, Cancer Epidemiology, Biomarkers and Prevention, 11, 73-77, January 2002
  • Bossetti C, Kolonel L, Negri E, Ron E, Franceschi S, Dal Maso L, Galanti MR, Mark SD, Preston-Martin S, McTiernan A, Land C, Mabuchi K, Jin F, Wingren G, Hallquist H, Glattre E, Lund E, Levi F, Linos D, LaVecchia C, A pooled analysis of case-control studies of thyroid cancer. VII. Cruciferous and other vegetables, Cancer Causes and Control, 13, 765-775, 2002
  • Morimoto L, White E, Zhao C, Chlebowski R, Hays J, Lopez AM, Manson J, Margolis K, Muti P, Stefanick M, McTiernan A, Obesity, body size, and risk of postmenopausal breast cancer: The Women's Health Initiative, Cancer Causes and Control, 13, 741-751, 2002
  • Evanson K, Wilxox S, Pettinger M, Brunner R, King AC, McTiernan A, Vigorous Leisure Activity through Women's Adult Life: The Women's Heath Observational Cohort Study, American Journal of Epidemiology, 156, 945-953, 2002
  • Bowen D, Burke W, Anderson S, Yasui Y, McLaren D, McTiernan A, Durfy S, Effects of risk counseling on interest in genetic testing, Genetics in Medicine, 4, 359-365, 2002
  • Chlebowski RT, Aiello E, McTiernan A, Weight loss in breast cancer patient management, Journal of Clinical Oncology, 20(4), 1128-1143, 2002
  • Barrett-Connor E, Hendrix S, Ettinger B, Wenger NK, Paoletti R, Lendant CJM, Pinn VW, Birkhause MH, McTiernan A, et. al., Best Clinical Practices: A Comprehensive Approach. In International Position Paper on Women's Health and Menopause, 271-288, 2002
  • LaVecchia C, Brinton L, McTiernan A, Hormone replacement therapy, realted therapies, and cancer. In International position paper on Women's Health and Menopause: A comprehensive approach, NIH publication no. 02-3284, 223-250, 2002
  • LaVecchia C, Brinton L, McTiernan A, Hormone replacement therapy, realted therapies, and cancer. In International position paper on Women's Health and Menopause: A comprehensive approach, NIH publication no. 02-3284, 223-250, 2002
  • Irwin ML, McTiernan A (2002) Exercise Effect on Body Weigh in Postmenopausal Women: The Physical Activity for Total Health Study, Women's Health and Menopause: New Strategies - Improved Quality of Life (345), 352
  • Wenger N K, Paoletti R, Lenfant CJM, Pinn VW, Barrett-Connor E, Birkhauser MH, Binton LA, Collins A, Collins P, Crosignani PG, Dennerstein L, Ettinger B, Gustafson JA, Guthrie J, Henderson S, Klein BEK, LaVeccia C, Lindsay R, Maggi A, McGowan JA, McTiernan A, Nilsson S, Redford M, Resnick SM, Rossuow JE, Santoro N, Sherman SS (2002) International Positional Paper on Women's Health and Menopause: A Comprehensive Approach, 02-3284, 1-22
  • Byers T, Nestle M, McTiernan A, Doyle C, Currie-Williams A, Gansler T, Thun M, American Cancer Society 2001 Nutrition and Physical Activity Guidelines Advisory Committee (Mar-Apr 2002) American Cancer Society guidelines on nutrition and physical activity for cancer prevention: Reducing the risk of cancer with healthy food choices and physical activity., Ca: a Cancer Journal for Clinicians, 52 (2), 92-119 Abstract
  • Shors AR, Solomon C, McTiernan A, Melanoma risk in relation to height, weight, and exercise (United States), Cancer Causes and Control, 12(7), 599-606, September 2001
  • Bosetti C, Kolonel L, Negri E, Ron E, Franceschi S, Dal Maso L, Galanti MR, Mark SD, Preston-Martin S, McTiernan A, Land C, Jin F, Wingren G, Hallquist A, Glattre E, Lund E, Levi F, Linos D, La Vecchia C (May 2001) A pooled analysis of case-control studies of thyroid cancer. VI. Fish and shellfish consumption., Cancer Causes & Control : Ccc, 12 (4), 375-82 Abstract
  • Young SYN, Gunzenhauser JD, Malone KE, McTiernan A, The relationship between body mass index and asthma in the military population of the northwestern United States, 161, 1605-1611, 2001
  • Tavani A, LaVecchia C, Brinton LA, McTiernan A, Hormone replacement therapy and risk of endometrial cancer, Tumori, 87(5), S20-1, 2001
  • LaVecchia C, Brinton LA, McTiernan A, Hormone replacement therapy and breast cancer risk: Epidemiology, Journal of Menopause, 8, 5-7, 2001
  • Davidoff R, McTiernan A, Constantine G, Davis KD, Balady GJ, Mendes LA, Rudolph RE, Bowen DJ, Echocardiographic evaluation of women previously treated with fenfluramine: Long-term follow-up of a randomized, double-blind, placebo-controlled trial, Archives of Internal Medicine, 161, 1429-1436, 2001
  • McTiernan A, Burke W, Bars J, et.al., Comparison of two breast cancer risk estimates in women with a family history of breast cancer, Cancer Epidemiology, Biomarkers and Prevention, 10, 333-338, 2001
  • LaVecchia C, Brinton L, McTiernan A, Menopause, hormone replacement therapy and cancer, Maturitas, 39, 97-115, 2001
  • International Agency for Research on Cancer (2001) IARC Handbooks of Cancer Prevention, Vol. 6, Weight Control and Physical Activity, Lyon, IARC Press
  • McTiernan A, Gralow J, Talbott L (2000) Breast Fitness: An Optimal Exercise and Health Plan for Reducing Your Risk of Breast Cancer, New York, St. Martin's Press
  • Burke W, Culver JO, Bowen D, Lowry D, Durfy S, McTiernan A, Andersen MR, Genetic counseling for women with an intermediate family history of breast cancer, American Journal of Medical Genetics, 90(5), 361-8, February 2000 Abstract
  • McTiernan A, Associations between Energy Balance and Body Mass Index and Risk of Breast carcinoma in Women from Diverse Racial and Ethnic Backgrounds in the U.S, Cancer, 88, 1248-55, 2000
  • Physical Activity and the Prevention of Breast Cancer, Medscape, 2000
  • Wingo PA, Calle EE, McTiernan A, How does breast cancer mortality compare with other cancers and cardiovascular disease at different ages in U.S. women?, Journal of Women's Health, 2000
  • Bowen DJ, Burke W, McTiernan A, Effects of risk counseling on interest in genetic testing, Community Genetics, 2000
  • Bowen D, Powers D, Anderson R, Burke W, McTiernan A, Durfy S, Predicting breast cancer screening with emotion and cognition, Journal of Social and Clinical Psychology, 2000
  • Davidoff R, McTiernan A, Constantine G, Davis KD, Balady GJ, Mendes DA, Rudolph R, Bowen DJ, Echocardiographic evaluation of women previously treated with fenfluramine: Long-term follow up of a randomized, double-blind, placebo-controlled trial, Archives of Internal Medicine, 2000
  • Bowen DJ, McTiernan A, Rosenberg E, Powers P, Fen Z, Recruiting women into a smoking cessation program to control weight: Who might quit?, Women and Health, 2000
  • Rosenblatt KA, Thomas DB, Jimenez LM, Fish B, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen MG, Satariano W, Austin DF, Greenberg RS, Key C, Kolonel LN, West DW, The relationship between diet and breast cancer in men (United States), Cancer Causes and Control, 10(2), 107-13, April 1999 Abstract
  • Durfy SJ, Bowen DJ, McTiernan A, Sporleder J, Burke W, Attitudes and interest in genetic testing for breast and ovarian cancer susceptibility in diverse groups of women in western Washington, Cancer Epidemiology, Biomarkers and Prevention, 8(4 Pt 2), 369-75, April 1999 Abstract
  • Negri E, Dal Maso L, Ron E, La Vecchia C, Mark SD, Preston-Martin S, McTiernan A, Kolonel L, Yoshimoto Y, Jin F, Wingren G, Rosaria Galanti M, Hardell L, Glattre E, Lund E, Levi F, Linos D, Braga C, Franceschi S, A pooled analysis of case-control studies of thyroid cancer. II. Menstrual and reproductive factors, Cancer Causes and Control, 10(2), 143-55, April 1999 Abstract
  • Negri E, Ron E, Franceschi S, Dal Maso L, Mark SD, Preston-Martin S, McTiernan A, Kolonel L, Kleinerman R, Land C, Jin F, Wingren G, Galanti MR, Hallquist A, Glattre E, Lund E, Levi F, Linos D, Braga C, La Vecchia C, A pooled analysis of case-control studies of thyroid cancer. I. Methods, Cancer Causes and Control, 10(2), 131-42, April 1999 Abstract
  • McTiernan A, Schwartz RS, Potter J, Bowen D, Exercise clinical trials in cancer prevention research: a call to action, Cancer Epidemiology, Biomarkers and Prevention, 8(3), 201-7, March 1999 Abstract
  • Chlebowski RT, McTiernan A, Elements of informed consent for hormone replacement therapy in patients with diagnosed breast cancer, Journal of Clinical Oncology, 17(1), 130-42, Jan 1999 Abstract
  • LaVecchia C, Ron E, Franceschi S, DalMaso L, Mark SD, Chatenoud L, Braga C, Preston-Martin S, McTiernan A, Oral contraceptives, menopausal replacement treatment and other female hormones and thyroid cancer, Cancer Causes and Control, 10, 157-166, 1999
  • McTiernan A, Ulrich CM, Yancey D, Slate S, Nakamura H, Oestreicher N, Bowen D, Yasui Y, Potter J, and Schwartz E, The Physical Activity for Total Health (PATH) Study: Rationale and Design, Medicine and Science in Sports and Exercise, 31, 1307-1312, 1999
  • Bowen D, McTiernan A, Burke W, Powers D, Pruski J, Durfy S, Gralow J, Malone K, Participation in breast cancer risk counseling among women with a family history, Cancer Epidemiology, Biomarkers and Prevention, 8, 581-586, 1999
  • Franceschi S, Preston-Martin S, DalMaso L, Negri E, LaVecchia C, McTiernan, Kolonel L, Mark S, Mabuchi K, Jin F, Wingre G, Dalanti R, Hallquist A, Glattre E, Lund E, Linos D, and Ron E, A pooled analysis of thyroid cancer case-control studies. IV. Benign thyroid disease, Cancer Causes and Control, 10, 583-595, 1999
  • McTiernan A, Ulrich C, Slate S, Potter J, Physical activity and cancer etiology: associations and mechanisms, Cancer Causes and Control, 9(5), 487-509, October 1998 Abstract
  • Hoffman-Goetz L, Apter D, Demark-Wahnefried W, Goran MI, McTiernan A, Reichman ME, Possible mechanisms mediating an association between physical activity and breast cancer, Cancer, 83(3 Suppl), 621-8, August 1998 Abstract
  • McTiernan A, Stanford JL, Daling JR, Voigt LF, Prevalence and correlates of recreational physical activity in women aged 50-64 years, Menopause, 5(2), 95-101, Summer 1998 Abstract
  • McTiernan A, Ulrich C, Kumai C, Bean D, Schwartz R, Mahloch J, Hastings R, Gralow J, Potter JD, Anthropometric and hormone effects of an eight-week exercise-diet intervention in breast cancer patients: results of a pilot study, Cancer Epidemiology, Biomarkers and Prevention, 7(6), 477-81, June 1998 Abstract
  • Design of the Women's Health Initiative Clinical Trial and Observational Study, Controlled Clinical Trials, 19, 61-109, 1998
  • McTiernan A, Gilligan MA, Redmond C, Assessing individual risk for breast cancer: risky business, Journal of Clinical Epidemiology, 50(5), 547-56, May 1997 Abstract
  • Burke W, Peterson G, Lynch P, Botkin J, Daly M, Garber J, Kahn MJE, McTiernan A, Offitt K, Thomson E, Varricchio C, for the Cancer Genetics Studies Consortium, Recommendations for follow-up care of individuals with an inherited predisposition to cancer. 1. Hereditary nonpolyposis colon cancer, JAMA, 277, 915-919, 1997
  • Burke W, Peterson G, Lynch P, Botkin J, Daly M, Garber J, Kahn MJE, McTiernan A, Offitt K, Thomson E, Varricchio C, for the Cancer Genetics Studies Consortium, Recommendations for follow-up care of individuals with an inherited predisposition to cancer. 2.BRCA1 and BRCA2, JAMA, 277, 997-1003, 1997
  • McTiernan A, Stanford JL, Weiss NS, Daling JR, Voigt LF, Occurrence of breast cancer in relation to recreational exercise in women age 50-64 years, Epidemiology, 7, 598-604, 1996
  • Prentice R, Rossouw JR, Johnson SR, Freedman LS, McTiernan A, The role of randomized controlled trial in assessing the benefits and risk of long-term hormone replacement therapy: Example of the Women's Health Initiative, Menopause, 3, 71-76, 1996
  • McTiernan A, Rossouw J, Manson J, Franzi C, Taylor V, Carleton R, Johnson S, and Nevitt M, Informed Consent in the Women's Health Initiative Clinical Trial and Observatrional Study, Journal of Women's Health, 4, 519-529, 1995
  • Bowen D, Green P, Kestin M, McTiernan A, Carroll D, Effects of decreasing dietary fat on psychological well-being, Cancer Epidemiology, Biomarkers and Prevention, 4, 555-559, 1995
  • Thomas DB, Rosenblatt K, Jimenez LM, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen MG, Satariano W, Austin DF, et al, Ionizing radiation and breast cancer in men (United States), Cancer Causes and Control, 5(1), 9-14, January 1994 Abstract
  • Stalsberg H, Thomas DB, Rosenblatt KA, Jimenez LM, McTiernan A, Stemhagen A, Thompson WD, Curnen MG, Satariano W, Austin DF, et al, Histologic types and hormone receptors in breast cancer in men: a population-based study in 282 United States men, Cancer Causes and Control, 4(2), 143-51, March 1993 Abstract
  • Thomas DB, Jimenez LM, McTiernan A, Rosenblatt K, Stalsberg H, Stemhagen A, Thompson WD, Curnen MG, Satariano W, Austin DF, et al, Breast cancer in men: risk factors with hormonal implications, American Journal of Epidemiology, 135(7), 734-48, April 1992 Abstract
  • Demers PA, Thomas DB, Rosenblatt KA, Jimenez LM, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen MG, Satariano W, et al, Occupational exposure to electromagnetic fields and breast cancer in men, American Journal of Epidemiology, 134(4), 340-7, August 1991 Abstract
  • McTiernan A, Weiss NS, Daling JR, Incidence of thyroid cancer in women in relation to known or suspected risk factors for breast cancer, Cancer Research, 47(1), 292-5, January 1987 Abstract
  • McTiernan A, Thomas DB, Johnson LK, Roseman D, Risk factors for estrogen receptor-rich and estrogen receptor-poor breast cancers, Journal of the National Cancer Institute, 77(4), 849-54, October 1986 Abstract
  • McTiernan A, Thomas DB, Evidence for a protective effect of lactation on risk of breast cancer in young women. Results from a case-control study, American Journal of Epidemiology, 124(3), 353-8, September 1986 Abstract
  • McTiernan A, Whitehead A, Thomas D, and Noonan E, Efficient selection of controls for multicentered collaborative studies of rare diseases, American Journal of Epidemiology, 901-904, 1986
  • Mueller B, McTiernan A, and Daling J, Level of response in epidemiologic studies using the card-back system to contact patients, American Journal of Public Health, 76(11), 1331-1332, 1986
  • McTiernan A, Weiss N, and Daling J, Bias resulting from using the card-back system to contact patients in epidemiologic studies, American Journal of Public Health, 76(1), 71-73, 1986
  • McTiernan A, Chu J, and Thomas D, Cancer in Whites in the Pacific Basin. In Fourth Symposium on Epidemiology and Cancer Registries in the Pacific Basin, National Cancer Institute Monograph, 69, 65-72, 1985
  • McTiernan AM, Weiss NS, Daling JR, Incidence of thyroid cancer in women in relation to previous exposure to radiation therapy and history of thyroid disease, Journal of the National Cancer Institute, 73(3), 575-81, September 1984 Abstract
  • McTiernan AM, Weiss NS, Daling JR, Incidence of thyroid cancer in women in relation to reproductive and hormonal factors, American Journal of Epidemiology, 120(3), 423-35, September 1984 Abstract
  • Shy KK, McTiernan AM, Daling JR, Weiss NS, Oral contraceptive use and the occurrence of pituitary prolactinoma, Jama, 249(16), 2204-7, April 1983 Abstract
  • Rosenberg C, Khandekar J, Greenberg P, Rodabough RJ, McTiernan A, Occurrence of Melanoma Following Nonmelanoma Skin Cancer - A Prospective Observational Study from the Women's Health Initiative, Cancer
  • International Position Paper on the Menopause (panel member), National Heart, Lung, and Blood Institute

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Last Verified: 8/4/2006

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