Michigan State University College of Agriculture & Natural Resources Animal Science Department Associate ProfessorAppointed: 1996 | |
QualificationsPh.D., Michigan State University, Animal Science, 1994. M.S., South Dakota State University, Animal Science, 1989. B.S., Washington State University, Animal Science, 1987. Expertise and Research InterestsDr. Doumit's research efforts are directed toward identifying hormonal and nutritional factors that regulate skeletal muscle growth. Current projects are focused on identifying causes for developmental changes in myoblast activity.
Dr. Doumit's laboratory is also involved in identifying biochemical markers which may be used to predict meat quality traits such as tenderness, color, and water-holding capacity. The goal of this research is to identify ways to more efficiently produce wholesome, palatable and nutritious meat products.
Research in Dr. Doumit's laboratory utilizes a variety of techniques including cell culture, protein characterization, immunocytochemistry, electrophoresis, Northern blot and Western blot analyses.
KeywordsCOS Keywords:Animal Science, Biochemical Markers, Cytology, Immunochemistry, Musculoskeletal System.MembershipsAmerican Association for the Advancement of Science American Meat Science Association American Society of Animal Science Sigma Xi, The Scientific Research Society Publications- Mesires NT, Doumit ME, Satellite cell proliferation and differentiation during postnatal growth
of porcine skeletal muscle, American Journal of Physiology. Cell Physiology, 282(4), C899-906, April 2002
 - Barker-Neef JM, Buskirk DD, Blackt JR, Doumit ME, Rust SR, Biological and economic performance of early-weaned Angus steers, Journal of Animal Science, 79(11), 2762-9, November 2001
 - Doumit ME, Koohmaraie M, Immunoblot analysis of calpastatin degradation: evidence for cleavage by
calpain in postmortem muscle, Journal of Animal Science, 77(6), 1467-73, June 1999
 - Fligger JM, Malven PV, Doumit ME, Merkel RA, Grant AL, Increases in insulin-like growth factor binding protein-2 accompany decreases in proliferation and differentiation when porcine muscle satellite cells undergo multiple passages, Journal of Animal Science, 76(8), 2086-93, August 1998
 - Koohmaraie M, Doumit ME, Wheeler TL, Meat toughening does not occur when rigor shortening is prevented, Journal of Animal Science, 74(12), 2935-42, December 1996
 - Doumit ME, Lonergan SM, Arbona JR, Killefer J, Koohmaraie M, Development of an enzyme-linked immunosorbent assay (ELISA) for quantification of skeletal muscle calpastatin, Journal of Animal Science, 74(11), 2679-86, November 1996
 - Doumit ME, Cook DR, Merkel RA, Testosterone up-regulates androgen receptors and decreases differentiation of porcine myogenic satellite cells in vitro, Endocrinology, 137(4), 1385-94, April 1996
 - Dodson MV, McFarland DC, Grant AL, Doumit ME, Velleman SG, Extrinsic regulation of domestic animal-derived satellite cells, Domestic Animal Endocrinology, 13(2), 107-26, March 1996
 - Koohmaraie M, Shackelford SD, Wheeler TL, Lonergan SM, Doumit ME, A muscle hypertrophy condition in lamb (callipyge): characterization of effects on muscle growth and meat quality traits, Journal of Animal Science, 73(12), 3596-607, December 1995
 - Doumit ME, Cook DR, Merkel RA, Fibroblast growth factor, epidermal growth factor, insulin-like growth factors, and platelet-derived growth factor-BB stimulate proliferation of clonally derived porcine myogenic satellite cells, Journal of Cellular Physiology, 157(2), 326-32, November 1993
 - Cook DR, Doumit ME, Merkel RA, Transforming growth factor-beta, basic fibroblast growth factor, and platelet-derived growth factor-BB interact to affect proliferation of clonally derived porcine satellite cells, Journal of Cellular Physiology, 157(2), 307-12, November 1993
 - Doumit ME, Merkel RA, Conditions for isolation and culture of porcine myogenic satellite cells, Tissue and Cell, 24(2), 253-62, 1992
 - Doumit ME, McFarland DC, Minshall RD, Satellite cells of growing turkeys: influence of donor age and sex on proliferation and differentiation in vitro, Experimental Cell Research, 189(1), 81-6, July 1990
 - Minshall RD, McFarland DC, Doumit ME, Interaction of insulin-like growth factor I with turkey satellite cells and satellite cell-derived myotubes, Domestic Animal Endocrinology, 7(3), 413-24, July 1990

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