Minesh Prafulchandra Mehta | |
University of Wisconsin-Madison School of Medicine and Public Health Human Oncology ProfessorAppointed: 2002 RTOG Brain Tumor Committee ChairAppointed: 1998 University of Wisconsin-Madison School of Medicine and Public Health Human Oncology ChairAppointed: 1997 |  |
QualificationsMBChB, University of Zambia, Medicine and Surgery, 1981. B.Sc., University of Zambia, Human Biology, 1978. Expertise and Research InterestsMy research interests are primarily in the areas of tomotherapy, incorporating advanced imaging in radiotherapy treatment planning, CNS malignancies, lung cancer, pediatric neoplasms, stereotactic radiosurgery, radiosensitization, combined modality therapies, altered fractionation, cost-effectiveness, and outcomes research. I am the PI for an NIH-funded Tomotherapy Program Project Grant. Within the context of CNS neoplasms, my particular expertise is in setting up and running multi-disciplinary clinics, conducting national multimodality protocols, participating in national organizational strategies for managing these tumors and developing radiosurgery systems and protocols. In addition, within this context, I have developed 3-D/conformal techniques as well as interstitial brachytherapy expertise. I have run numerous multimodality clinical trials at the national level for both adult and pediatric CNS neoplasms. Current major thrust areas include developing molecularly-targeted agents as radiosensitizers for CNS tumors, such as the EGFR pathway, PKC, angiogenesis, etc. I am the PI for an ongoing international Phase III trial of Motexafin-Gadolinium, a novel radiosensitizer, being evaluated in brain metastases patients. I am engaged in clinical trials combining Temozolomide with radiation therapy for CNS tumors. In addition, I am working with topoisomerase I inhibitors as radiosensitizers, for thoracic neoplasms, particularly small cell lung cancer. For the latter, I have developed a unique hyperfractionated, accelerated regimen, which has been tested in a national trial. As far as pediatric neoplasms are concerned, my major research focus has been on medulloblastoma. Outcomes research, with specific emphasis on cost-effectivenes, quality of life and neurocognitive function has been another important area of activity.
Other ExpertiseAdvisory Boards (Current (C) or Past (P)): Alpha Therapeutics (P) American Brain Tumor Association (C) Gammex RMI (C) Pediatric Brain Tumor Consortium (C) Philips Radiation Oncology Systems Medical Advisory Board (C) Procertus (C) TomoInc (C) Ultravisual Corporation (P)
Consultancy (Current or Past): ALZA MedImmune Peregrine Pharmacyclics Schering-Plough Neopharm Novartis
Honors: 1998-02 ASTRO: "Meet the Professors" Faculty 1998-9 The Best Doctors in America: Midwest Region 1998-9 The Best Doctors In America 1996-7 The Best Doctors In America: Midwest Region 1995 Year Book of Oncology 1993 ''Most important papers," International Monitor in Oncology 1992 ''Outstanding Article in the Field," Respiratory Diseases Digest 1990 Year Book of Otolaryngology 1988 American Board of Radiology Certification 1978 Highest Scoring BSc, University of Zambia Future ResearchOver the next 5 years, my reserach efforts are going to be focused on 4 broad areas: 1. Development of tomotherapy as a viable treatment technology in radiotherapy 2. Incorporation of advanced imaging, including fMR, MRS, DTI, BOLDMR, pMR and CT-PETin radiotherapy treatment planning 3. Evaluation of molecularly targeted therapies in combination with radiotherapy 4. Development of the concept of gadolinium-neutron capture therapy Industrial RelevanceI have advised several pharmaceutical corporations regarding product development, especially in the context of combining therapies with radiation therapy. I have a sophisticated understanding of the role and application of new and innovative technologies in radiotherapy, including the FDA processes. KeywordsCOS Keywords:Angiogenesis, Brain Tumors, Cancer Or Carcinogenesis, Central Nervous System, Clinical Trial, Lung Cancer, Metastasis, Oncology, Outcomes Research (Medical), Pediatrics, Quality of Life Program, Radiation Oncology, Radiotherapy, Surgery.Additional Terms:Brain Tumors, Cost-analysis, Lung Cancer, Medulloblastoma, Radiotherapy, Stereotactic Radiosurgery, Tomotherapy.Languages(Reading, Writing, Speaking)English: (Fluent, Fluent, Fluent) Gujarati: (Fluent, Fluent, Fluent) Hindi: (Functional, Basic, Basic) Swahili: (Basic, Basic, Basic) MembershipsAmerican Brachytherapy Society American Medical Association American Radium Society American Society of Clinical Oncology American Society of Therapeutic Radiology and Oncology Children's Oncology Group Eastern Cooperative Oncology Group Indo-American Cancer Congress International Association for the Study of Lung Cancer International Stereotactic Radiosurgery Society North American Brain Tumor Consortium Radiation Therapy Oncology Group Society for Neuro-Oncology Wisconsin Society of Radiation Oncologists Wisconsin State Medical Society Honors and Awards2003, Best Physicians,
Madison Business Magazine
2002, The Pancer Lecture,
University of Toronto & Princess Margaret Hospital
2002-2004,
Top Docs,
Madison Magazine
2001, 15th Annual Simon Kramer Lecture,
Thomas Jefferson University
1999, Nick Khadiwala Award for Excellence in Neuro-Oncology,
Colorado Neurological Institute
1998-1999,
The Best Doctors,
The Best Doctors In America
1998-2003,
Meet the Professors,
ASTRO
1996, Radiotherapy Teacher of the Year,
University of Wisconsin
1996-1999,
The Best Doctors In America,
Midwest Region
1995, Year Book,
Oncology
1994, Dean's Teaching Award,
University of Wisconsin
1993, Most Important Papers,
International Monitor in Oncology
1992, ASTRO Travel Reserach Award,
ASTRO
1992, Outstanding Article in the Field,
Respiratory Diseases Digest
1990, Radiotherapy Teacher of the Year,
University of Wisconsin
1990, Year Book,
Otolaryngology
1989-2001,
Physicians' Recognition Award,
AMA
1981, Raymond Radunski Award,
University of Zambia,
Best Overall Medical School Graduate
1981, Merck Sharpe and Dohme Prize,
University of Zambia,
Best Graduate, Internal Medicine
1981, Upjohns Prize,
University of Zambia,
Best Graduate, Pediatrics
1981, Hassim Lucas Prize,
University of Zambia,
Best Graduate, Obstetrics and Gynecology
1980, Billingsley Award,
University of Zambia,
Best Medical Student
1978, Highest Scoring BSc Degree,
University of Zambia
1975, Wildlife Conservation Prize,
University of Zambia,
Best Biology Freshman
1975, Kerry Gill Prize,
University of Zambia,
Best Chemistry Freshman
Previous Positions1997-1998, Interim Chair,
University of Wisconsin-Madison,
School of Medicine and Public Health,
Human Oncology
1996-1997, Vice Chair,
University of Wisconsin-Madison,
School of Medicine and Public Health,
Human Oncology
1994-1997, Director,
University of Wisconsin-Madison,
Radiation Oncology,
Residency Program
1994-2002, Associate Professor,
University of Wisconsin-Madison,
School of Medicine and Public Health,
Human Oncology
1988-1994, Assistant Professor,
University of Wisconsin-Madison,
Graduate School,
Human Oncology
Funding Received- National Institutes of Health (NIH):
RTOG CA 21661-27-33: PI: Curran W RTOG CA 21661-27-33: PI: Curran W, Brain Tumor Committee Chair: Mehta M, 5% effort and salary.,
~$86,000,000,
2002
to 2007.
- General Electric:
CT-PET for Radiotherapy Treatment Planning. Principal Investigator: Mehta MP, 5% effort.,
$220,000,
2002
to 2004.
- University of Wisconsin Comprehensive Cancer Center:
Subcellular localization of Gd for GdNCT. Co-Project Leader: Mehta MP, 5% effort.,
$100,000,
2002
to 2004.
- Schering Plough:
Phase II randomized trial of Whole Brain Radiotherapy plus Temozolomide or Placebo for Patients with Brain Metastases. PI: Mehta MP.,
$10,000,
2002
to 2002.
- National Institutes of Health (NIH):
P01 CA88960-01-05: Improving Cancer Outcome with Adaptive Helical Tomotherapy. PI, Project and Core Leader: Mehta MP, 20% effort and salary.,
$10,538,675,
2001
to 2006.
- National Institutes of Health (NIH):
NCI P30 CA14520-29: UW Comprehensive Cancer Center Support Grant. PI: Niederhuber J, Imaging and Radiation Sciences Program, Program Leader: Mehta M, 10% effort and salary .,
$17,302,845,
2001
to 2006.
- Pharmacyclics:
Phase II Motexafin Gadolinium for GBM. PI: Mehta M .,
$202,520,
2001
to 2002.
- National Institutes of Health (NIH):
NCI R43 AR47728-01: ProDermaCel: Topical Protector Against Chemo/Radiotherapy. PI: Fahl W, Collaborator & Consultant: Mehta MP, 5% effort.,
$99,475,
2001
to 2002.
- National Institutes of Health (NIH):
NCI K12 CA87718-01: Training Grant, PI: Schiller J, Co-investigator: Mehta, M (Trainer), 5% effort.,
$1,250,000,
2001
to 2006.
- University of Wisconsin Graduate School:
Subcellular localization of a novel Gd compound for Gadolinium Neutron Capture Therapy (GdNCT), PI: DeStasio, Co-investigator: Mehta, M, 2% effort .,
$30,000,
2001
to 2002.
- RTOG/Genentech:
Evaluate C-erb-B2 Expression in Malignant Glioma. PI: Mehta M, 2% effort.,
$21,156,
2001
to 2002.
- National Institutes of Health (NIH):
ECOG-WI 5U10 CA-21076-24-29: PI: Stewart J, Study Chair & Committee Vice Chair: Mehta M, 5% effort.,
$1,959,420,
1999
to 2004.
- University of Wisconsin Comprehensive Cancer Center:
Staging disease in patients with lung cancer using CT and PET. PI: Perlman S, Co-PI: Mehta M, 2% effort.,
$15,252,
1999
to 2002.
- National Institutes of Health (NIH):
RTOG CA 21661-24-26: PI: Curran W, Brain Tumor Committee Chair: Mehta M, 5% effort and salary.,
$8,459,153,
1999
to 2002.
- University of Wisconsin Comprehensive Cancer Center:
Advanced imaging technologies for brain tumor treatment planning. PI: Meyerand B, Co-PI: Mehta M, 2% effort.,
$20,000,
1999
to 2002.
- University Industry Relationship:
Industrial & Economic Development Research Fund: Development of a system for fractionated Stereotactic Radiotherapy/Tomotherapy to allow online patient repositioning. PI: Tome W, Co-PI: Mehta M, 2% effort.,
$29,902,
1999
to 2000.
- Varian Industries:
Multi-institutional analysis of radiosurgically treated brain metastases patients stratified by RTOG RPA Class, PI: Mehta M, 1% effort.,
$10,000,
1999
to 2000.
- North American Brain Tumor Consortium:
Novel Telomerase Inhibitors for Brain Tumor Therapy. PI: Mehta M, 5% effort.,
$30,010,
1999
to 2000.
- Bristol Myers:
Temozolomide and cis-retinoic acid for malignant glioma. PI: Mehta M.,
$15,000,
1999
to 2000.
- University of Wisconsin General Clinical Research Center:
Summer Research Grant: QOL tools for patients with brain metastases. PI: Mehta M .,
$7,500,
1999
to 1999.
- National Institutes of Health (NIH):
NCI U01 CA62421-05-09: Consortium Therapeutic Studies of Primary CNS Malignancies. PI: Mehta M,
$294,408,
1998
to 2002.
- National Institutes of Health (NIH):
NCI RO1 CA48902-09-11: Optimized Planning and Delivery of Radiotherapy. PI: Mackie TR, Co-Investigator Mehta M, 5% effort and salary.,
1998
to 2000.
- National Institutes of Health (NIH):
NCI P30 CA14520-26-29: UW Comprehensive Cancer Center Support Grant: Radiation Oncology and Physics Program Leader: Mehta M,, 10% effort and salary,,
1998
to 2001.
- Eli Lilly & Co:
Phase I study of Gemcitabine plus palliative radiation therapy for advanced lung cancer. PI: Mehta M.,
$92,920,
1998
to 1999.
- American Society for Therapeutic Radiology and Oncology:
ASTRO Research Training Fellowship Grant,
$35,000,
1998
to 1999.
- Pharmacyclics:
PCI-P120-9801: A phase III randomized trial of Gadolinium texaphyrin,
$130,400,
1998
to 2000.
- Pharmacyclics:
A Field Test of Brain Quality of Life Tools. PI: Mehta M.,
$7,920,
1998
to 1999.
- University of Wisconsin:
UW School of Medicine Educational Research and Development Grant: Development of WWW-based modules for Oncology Grand Rounds. Co-PI: Mehta M.,
$5,000,
1998
to 1999.
- Bristol-Myers Squibb:
Education Grant: Post-Mastectomy Radiation Therapy, ASTRO Consensus Conference,
$4,500,
1998
to .
- ADAC:
Technology Development Grant,
$75,000,
1998
to 2000.
- ADAC:
Development of radiosurgery teaching modules,
$10,000,
1998
to 1999.
- Varian:
Multi-institutional analysis of radiosurgery outcome of brain metastases patients by RTOG RPA Class.,
$15,000,
1998
to 1999.
- University of Wisconsin:
DoIt Technology Development Grant: Enhancement of WWW-aided Educational Tools for Neoplastic Diseases Course. PI: Mehta M.,
$750,
1997
to 1998.
- University of Wisconsin:
Radiation Therapy Technology Development Grant: Utilization of MRI and MRA in Radiosurgery Treatment Planning. PI: Mehta M.,
$23,000,
1997
to 1998.
- Pharmacyclics:
Phase Ib/II study of Gd-Texaphyrin and cranial radiation for brain metastases. PI: Mehta M.,
$80,058,
1997
to 1998.
- Laaitinen Corporation:
Fractionated radiosurgery frame and phantom development, equipment grant, PI: Mehta M.,
$15,000,
1997
to .
- University of Wisconsin:
UW School of Medicine Educational Research and Development Grant: Impact of WWW-aided Educational Tools on Neoplastic Diseases Course Learning. PI: Mehta M.,
$5,000,
1997
to 1998.
- ADAC Corporation:
Comparison of MRA and angiographic localization for AVM radiosurgery, equipment grant (Digitizer), PI: Mehta M,,
$5,000,
1997
to .
- SmithKline Beecham:
Kytril in Radiation Emesis, PI: Mehta M.,
$8,000,
1996
to 1997.
- American Cancer Society (ACS):
Clinical Oncology Training Fellowship Grant: PI: Mehta M.,
$10,000,
1995
to 1996.
- National Institutes of Health (NIH):
ECOG-WI 5U10 CA-21076-19-22: PI: Stewart J, Study Chair & Committee Vice Chair: Mehta M.,
1994
to 1998.
- National Institutes of Health (NIH):
NCI UO1 CA-62491: Phase I Clinical Trials of Novel Anti-Cancer Therapies. PI: Wilding G, Co-PI: Mehta M,
1994
to 1998.
- National Institutes of Health (NIH):
NCI U01 CA-6242101-04: Therapeutic Studies of Primary CNS Malignancies in Adults. PI: Mehta M.,
$111,000,
1994
to 1997.
- National Institutes of Health (NIH):
NCI 5U10 CA-05436: CCG Grant, PI: Gaynon P, Co-investigator: Mehta M.,
1993
to 1998.
- U.S. Biosciences:
UW133-W172: Nursing and Clinical Research Fellowship, PI: Schiller J, Co-PI: Mehta M.,
$10,000,
1993
to 1995.
- Amgen:
Effects of rh-GCSF on Neutropenia Induced by Whole Abdominal Radiation Therapy, PI: Mehta M.,
$10,000,
1992
to 1993.
- American Society for Therapeutic Radiation Oncology:
Travel Research Grant: Radiosurgery, Karolinska Hospital, Stockholm, Sweden.,
$5,000,
1992
to .
- Radionics:
MRA for AVM Radiosurgery Planning BRW MR Frame, equipment grant. PI: Mehta M.,
$6,000,
1991
to .
- U.S. Biosciences:
UW133-R860: A Phase II Study of Cisplatin/Vinblastine and WR 2721 Plus Radiotherapy and WR 2721 in Patients with Locally Advanced Non-Small Cell Lung Cancer, PI: Schiller J, Co-PI: Mehta M.,
$90,000,
1990
to 1995.
- Alpha Therapeutics:
Fluosol as an Adjuvant to Combination Whole Brain Radiation Therapy and Stereotactic Radiosurgery in the Treatment of Metastatic Brain Tumors, PI: Mehta M.,
$50,000,
1990
to 1992.
- American Medical Association:
Bronchioalveolar Lavage in Radiation-Associated Pneumonitis, PI: Jarjour N, Co-PI: Mehta M.,
$40,000,
1990
to .
- Hoechst-Roussel Pharmaceutical:
Pentoxyfilline for Radiation Myelitis, PI: Rodriguez R, Co-PI: Mehta M.,
$8,000,
1990
to .
- U.S. Biosciences:
UW133-N931: Pilot Study of Cisplatin/Vinblastine and WR 2721 Plus Radiotherapy and WR 2721 in Locally Advanced Lung Cancer, PI: Schiller J, Co-PI: Mehta M.,
$10,500,
1989
to 1992.
- COTA Biotech Grant:
COTA Monoclonal Antibody for Early Detection of Colorectal Cancer, PI: Mehta M.,
$5,000,
1989
to 1990.
- Alpha Therapeutics:
Phase III Randomized Fluosol Head and Neck Study, PI: Mehta M.,
$26,000,
1988
to 1990.
- Alpha Therapeutics:
Oxygen Probe Study, PI: Mehta M.,
$5,000,
1988
to .
- Carrington Industries:
Acute Skin Reaction Study, PI: Mehta M.,
$10,000,
1987
to 1988.
- American Cancer Society (ACS):
ACS 1N-35-28-13: Radiolabeled Monoclonal Dosimetry, PI: Mehta M.,
$10,000,
1986
to 1986.
Publications- Mehta MP, Khuntia D (Nov 2005) Current strategies in whole-brain radiation therapy for brain metastases., Neurosurgery, 57 (5 Suppl), S33-44; discusssion
 - Hong TS, Mehta MP, Boyett JM, Donahue B, Rorke LB, Zeltzer PM (Oct 2005) Patterns of treatment failure in infants with primitive neuroectodermal
tumors who were treated on CCG-921: a phase III combined modality
study., 45 (5), 676-82
 - Langer CJ, Mehta MP, Current Management of Brain Metastases, With a Focus on Systemic Options., Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 23(25), 6207-19, Sep 2005
 - Packer RJ, Krailo M, Mehta M, Warren K, Allen J, Jakacki R, Villablanca JG, Chiba A, Reaman G (Sep 2005) Phase 1 study of concurrent RMP-7 and carboplatin with radiotherapy for
children with newly diagnosed brainstem gliomas., 104 (6), 1281-7
 - Tsao MN, Mehta MP, Whelan TJ, Morris DE, Hayman JA, Flickinger JC, Mills M, Rogers CL, Souhami L (Sep 2005) The American Society for Therapeutic Radiology and Oncology (ASTRO)
evidence-based review of the role of radiosurgery for malignant
glioma., 63 (1), 47-55
 - Cloughesy TF, Kuhn J, Robins HI, Abrey L, Wen P, Fink K, Lieberman FS, Mehta M, Chang S, Yung A, DeAngelis L, Schiff D, Junck L, Groves M, Paquette S, Wright J, Lamborn K, Sebti SM, Prados M (Sep 2005) Phase I trial of tipifarnib in patients with recurrent malignant glioma
taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor
Consortium Study., 23 (27), 6647-56
 - Langer CJ, Mehta MP (Sep 2005) Current management of brain metastases, with a focus on systemic options., Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 23 (25), 6207-19
 - Mehta MP, Tsao MN, Whelan TJ, Morris DE, Hayman JA, Flickinger JC, Mills M, Rogers CL, Souhami L (Sep 2005) The American Society for Therapeutic Radiology and Oncology (ASTRO)
evidence-based review of the role of radiosurgery for brain
metastases., 63 (1), 37-46
 - Chakravarti A, Seiferheld W, Tu X, Wang H, Zhang HZ, Ang KK, Hammond E, Curran W Jr, Mehta M, Immunohistochemically Determined Total Epidermal Growth Factor Receptor
Levels Not of Prognostic Value in Newly Diagnosed Glioblastoma Multiforme:
Report From the Radiation Therapy Oncology Group., International Journal of Radiation Oncology, Biology, Physics, 62(2), 318-27, Jun 2005
 - Belani CP, Wang W, Johnson DH, Wagner H, Schiller J, Veeder M, Mehta M, Eastern Cooperative Oncology Group, Phase III Study of the Eastern Cooperative Oncology Group (ECOG 2597):
Induction Chemotherapy Followed By Either Standard Thoracic Radiotherapy
Or Hyperfractionated Accelerated Radiotherapy for Patients With
Unresectable Stage IIIA and, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 23(16), 3760-7, Jun 2005
 - De Stasio G, Rajesh D, Casalbore P, Daniels MJ, Erhardt RJ, Frazer BH, Wiese LM, Richter KL, Sonderegger BR, Gilbert B, Schaub S, Cannara RJ, Crawford JF, Gilles MK, Tyliszczak T, Fowler JF, Larocca LM, Howard SP, Mercanti D, Mehta MP, Pallini R (Jun 2005) Are gadolinium contrast agents suitable for gadolinium neutron capture
therapy?, 27 (4), 387-98
 - Belani CP, Wang W, Johnson DH, Wagner H, Schiller J, Veeder M, Mehta M, Eastern Cooperative Oncology Group (Jun 2005) Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597):
induction chemotherapy followed by either standard thoracic radiotherapy
or hyperfractionated accelerated radiotherapy for patients with
unresectable stage IIIA and B, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 23 (16), 3760-7
 - Petereit DG, Rogers D, Burhansstipanov L, Kaur J, Govern F, Howard SP, Osburn CH, Coleman CN, Fowler JF, Chappell R, Mehta MP, Walking Forward: the South Dakota Native American Project., Journal of Cancer Education : the Official Journal of the American Association for Cancer Education., 20(1 Suppl), 65-70, Spring 2005
 - Mehta M, Manon R (Apr 2005) Are more aggressive therapies able to improve treatment of locally
advanced non-small cell lung cancer: combined modality
treatment?, Seminars in Oncology, 32 (2 Suppl 3), S25-34
 - Petereit DG, Rogers D, Burhansstipanov L, Kaur J, Govern F, Howard SP, Osburn CH, Coleman CN, Fowler JF, Chappell R, Mehta MP (Spring 2005) Walking forward: the South Dakota Native American project., Journal of Cancer Education : the Official Journal of the American Association for Cancer Education., 20 (1 Suppl), 65-70
 - Hong TS, Tome WA, Chappell RJ, Chinnaiyan P, Mehta MP, Harari PM, The Impact of Daily Setup Variations on Head-and-neck Intensity-modulated
Radiation Therapy., International Journal of Radiation Oncology, Biology, Physics, 61(3), 779-88, Mar 2005
 - Hong TS, Tome WA, Chappell RJ, Chinnaiyan P, Mehta MP, Harari PM (Mar 2005) The impact of daily setup variations on head-and-neck intensity-modulated
radiation therapy., International Journal of Radiation Oncology, Biology, Physics, 61 (3), 779-88
 - Mehta M, Fowler J, Accelerated Hypofractionation., International Journal of Radiation Oncology, Biology, Physics, 61(1), 299-300; author repl, Jan 2005
 - Mehta M, Fowler J, Accelerated hypofractionation., International Journal of Radiation Oncology, Biology, Physics, 61(1), 299-300; author repl, Jan 2005
 - Mehta M, Bradley K (2005) Radiation therapy for leptomeningeal cancer., Cancer Treatment and Research, 125, 147-58
 - Khuntia D, Mehta M, Motexafin Gadolinium: a Clinical Review of a Novel Radioenhancer for Brain
Tumors., Expert Review of Anticancer Therapy, 4(6), 981-9, Dec 2004
 - Khuntia D, Mehta M, Motexafin Gadolinium: a Clinical Review of a Novel Radioenhancer for Brain
Tumors., Expert Review of Anticancer Therapy, 4(6), 981-9, Dec 2004
 - Mehta MP, Suh JH, Novel Radiosensitizers for Tumors of the Central Nervous System., Current Opinion in Investigational Drugs (london, England : 2000), 5(12), 1284-91, Dec 2004
 - Forrest LJ, Mackie TR, Ruchala K, Turek M, Kapatoes J, Jaradat H, Hui S, Balog J, Vail DM, Mehta MP, The Utility of Megavoltage Computed Tomography Images From a Helical
Tomotherapy System for Setup Verification Purposes., International Journal of Radiation Oncology, Biology, Physics, 60(5), 1639-44, Dec 2004
 - Hui SK, Das RK, Kapatoes J, Oliviera G, Becker S, Odau H, Fenwick JD, Patel R, Kuske R, Mehta M, Paliwal B, Mackie TR, Fowler JF, Welsh JS, Helical Tomotherapy As a Means of Delivering Accelerated Partial Breast
Irradiation., Technology in Cancer Research & Treatment, 3(6), 639-46, Dec 2004
 - Khuntia D, Mehta M (Dec 2004) Motexafin gadolinium: a clinical review of a novel radioenhancer for brain
tumors., Expert Review of Anticancer Therapy, 4 (6), 981-9
 - Khuntia D, Mehta M (Dec 2004) Motexafin gadolinium: a clinical review of a novel radioenhancer for brain
tumors., Expert Review of Anticancer Therapy, 4 (6), 981-9
 - Fowler JF, Tome WA, Fenwick JD, Mehta MP, A challenge to traditional radiation oncology, International Journal of Radiation Oncology, Biology, Physics, 60(4), 1241-56, Nov 2004
 - Petereit DG, Rogers D, Govern F, Coleman N, Osburn CH, Howard SP, Kaur J, Burhansstipanov L, Fowler CJ, Chappell R, Mehta MP, Increasing access to clinical cancer trials and emerging technologies for
minority populations: the Native American Project, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 22(22), 4452-5, Nov 2004
 - Souhami L, Seiferheld W, Brachman D, Podgorsak EB, Werner-Wasik M, Lustig R, Schultz CJ, Sause W, Okunieff P, Buckner J, Zamorano L, Mehta MP, Curran WJ Jr, Randomized comparison of stereotactic radiosurgery followed by
conventional radiotherapy with carmustine to conventional radiotherapy
with carmustine for patients with glioblastoma multifo, International Journal of Radiation Oncology, Biology, Physics, 60(3), 853-60, Nov 2004
 - Puduvalli VK, Yung WK, Hess KR, Kuhn JG, Groves MD, Levin VA, Zwiebel J, Chang SM, Cloughesy TF, Junck L, Wen P, Lieberman F, Conrad CA, Gilbert MR, Meyers CA, Liu V, Mehta MP, Nicholas MK, Prados M, North American Brain Tumor Consortium, Phase II study of fenretinide (NSC 374551) in adults with recurrent
malignant gliomas: A North American Brain Tumor Consortium
study, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 22(21), 4282-9, Nov 2004
 - Potters L, Steinberg M, Rose C, Timmerman R, Ryu S, Hevezi JM, Welsh J, Mehta M, Larson DA, Janjan NA, American Society for Therapeutic Radiology and Oncology, American College of Radiology, American Society for Therapeutic Radiology and Oncology and American
College of Radiology practice guideline for the performance of
stereotactic body radiation therapy, International Journal of Radiation Oncology, Biology, Physics, 60(4), 1026-32, Nov 2004
 - Bradley KA, Mehta MP, Management of brain metastases, Seminars in Oncology, 31(5), 693-701, Oct 2004
 - Hong TS, Mehta MP, Boyett JM, Donahue B, Rorke LB, Yao MS, Zeltzer PM, Patterns of failure in supratentorial primitive neuroectodermal tumors
treated in Children's Cancer Group Study 921, a phase III combined
modality study, International Journal of Radiation Oncology, Biology, Physics, 60(1), 204-13, September 2004
 - Schulz CA, Mehta MP, Badie B, McGinn CJ, Robins HI, Hayes L, Chappell R, Volkman J, Binger K, Arzoomanian R, Simon K, Alberti D, Feierabend C, Tutsch KD, Kunugi KA, Wilding G, Kinsella TJ, Continuous 28-day iododeoxyuridine infusion and hyperfractionated
accelerated radiotherapy for malignant glioma: a phase I clinical
study, International Journal of Radiation Oncology, Biology, Physics, 59(4), 1107-15, July 2004
 - Chang SM, Seiferheld W, Curran W, Share R, Atkins J, Choucair A, Kresl J, Thoron L, Cairncross G, Gilbert M, Bahary JP, Dolinskas C, Louis DN, Bushunow P, Buckner J, Barger G, Mehta M, Phase I study pilot arms of radiotherapy and carmustine with temozolomide
for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813):
implications for studies testing initial treat, International Journal of Radiation Oncology, Biology, Physics, 59(4), 1122-6, July 2004
 - Nieder C, Grosu AL, Mehta MP, Andratschke N, Molls M, Treatment of Malignant Gliomas: Radiotherapy, Chemotherapy and Integration
of New Targeted Agents., Expert Rev Neurother, 4(4), 691-703, Jul 2004
 - Nieder C, Grosu AL, Mehta MP, Andratschke N, Molls M (Jul 2004) Treatment of malignant gliomas: radiotherapy, chemotherapy and integration
of new targeted agents., Expert Rev Neurother, 4 (4), 691-703
 - Manon R, Hui S, Chinnaiyan P, Suh J, Chang E, Timmerman R, Phan S, Das R, Mehta M, The impact of mid-treatment MRI on defining boost volumes in the radiation
treatment of glioblastoma multiforme, Technology in Cancer Research & Treatment, 3(3), 303-7, June 2004
 - Andrews DW, Scott CB, Sperduto PW, Flanders AE, Gaspar LE, Schell MC, Werner-Wasik M, Demas W, Ryu J, Bahary JP, Souhami L, Rotman M, Mehta MP, Curran WJ Jr, Whole brain radiation therapy with or without stereotactic radiosurgery
boost for patients with one to three brain metastases: phase III results
of the RTOG 9508 randomised trial, Lancet, 363(9422), 1665-72, May 2004
 - Chang SM, Prados MD, Yung WK, Fine H, Junck L, Greenberg H, Robins HI, Mehta M, Fink KL, Jaeckle KA, Kuhn J, Hess K, Schold C, Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and
temozolomide for newly diagnosed anaplastic glioma: a North American Brain
Tumor Consortium Trial, Cancer, 100(8), 1712-6, 2004
 - Forouzannia A, Schiller J, Berlin J, Hutson P, Boothman D, Storer B, Wilding G, Mehta M, A phase I study of Topotecan, as a radiosensitizer, for thoracic
malignancies, Lung Cancer (amsterdam, Netherlands), 44(1), 111-9, April 2004
 - Brat DJ, Seiferheld WF, Perry A, Hammond EH, Murray KJ, Schulsinger AR, Mehta MP, Curran WJ, Radiation Therapy Oncology Group, Analysis of 1p, 19q, 9p, and 10q as prognostic markers for high-grade
astrocytomas using fluorescence in situ hybridization on tissue
microarrays from Radiation Therapy Oncology Group tria, Neuro-oncology, 6(2), 96-103, April 2004
 - Regine WF, Schmitt FA, Scott CB, Dearth C, Patchell RA, Nichols RC Jr, Gore EM, Franklin RL 3rd, Suh JH, Mehta MP, Feasibility of neurocognitive outcome evaluations in patients with brain
metastases in a multi-institutional cooperative group setting: results of
Radiation Therapy Oncology Group trial BR, International Journal of Radiation Oncology, Biology, Physics, 58(5), 1346-52, April 2004
 - Welsh JS, Bradley K, Ruchala KJ, Mackie TR, Manon R, Patel R, Wiederholt P, Lock M, Hui S, Mehta MP, Megavoltage computed tomography imaging: a potential tool to guide and
improve the delivery of thoracic radiation therapy, Clinical Lung Cancer, 5(5), 303-6, March 2004
 - Chakravarti A, Dicker A, Mehta M, The contribution of epidermal growth factor receptor (EGFR) signaling
pathway to radioresistance in human gliomas: a review of preclinical and
correlative clinical data, International Journal of Radiation Oncology, Biology, Physics, 58(3), 927-31, March 2004
 - Harari PM, Ritter MA, Petereit DG, Mehta MP, Chemoradiation for upper aerodigestive tract cancer: balancing evidence
from clinical trials with individual patient recommendations, Current Problems in Cancer, 28(1), 7-40, 2004
 - Schold SC Jr, Kokkinakis DM, Chang SM, Berger MS, Hess KR, Schiff D, Robins HI, Mehta MP, Fink KL, Davis RL, Prados MD, O6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in
anaplastic gliomas, Neuro-oncology, 6(1), 28-32, January 2004
 - Prados MD, Yung WK, Fine HA, Greenberg HS, Junck L, Chang SM, Nicholas MK, Robins HI, Mehta MP, Fink KL, Jaeckle KA, Kuhn J, Hess KR, Schold SC Jr, North American Brain Tumor Consortium study, Phase 2 study of BCNU and temozolomide for recurrent glioblastoma
multiforme: North American Brain Tumor Consortium study, Neuro-oncology, 6(1), 33-7, January 2004
 - Prados MD, Yung WK, Jaeckle KA, Robins HI, Mehta MP, Fine HA, Wen PY, Cloughesy TF, Chang SM, Nicholas MK, Schiff D, Greenberg HS, Junck L, Fink KL, Hess KR, Kuhn J, North American Brain Tumor Consortium study, Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant
glioma: a North American Brain Tumor Consortium study, Neuro-oncology, 6(1), 44-54, January 2004
 - Meyers CA, Smith JA, Bezjak A, Mehta MP, Liebmann J, Illidge T, Kunkler I, Caudrelier JM, Eisenberg PD, Meerwaldt J, Siemers R, Carrie C, Gaspar LE, Curran W, Phan SC, Miller RA, Renschler MF, Neurocognitive function and progression in patients with brain metastases
treated with whole-brain radiation and motexafin gadolinium: results of a
randomized phase III trial, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 22(1), 157-65, January 2004
 - Chang SM, Kuhn JG, Ian Robins H, Clifford Schold S, Spence AM, Berger MS, Mehta MP, Pollack I, Gilbert M, Prados MD, A study of a different dose-intense infusion schedule of phenylacetate in
patients with recurrent primary brain tumors, Investigational New Drugs, 21(4), 429-33, November 2003
 - Robins HI, Peterson CG, Mehta MP, Combined modality treatment for central nervous system malignancies, Seminars in Oncology, 30(4 Suppl 9), 11-22, August 2003
 - Mehta MP, Rodrigus P, Terhaard CH, Rao A, Suh J, Roa W, Souhami L, Bezjak A, Leibenhaut M, Komaki R, Schultz C, Timmerman R, Curran W, Smith J, Phan SC, Miller RA, Renschler MF, Survival and neurologic outcomes in a randomized trial of motexafin
gadolinium and whole-brain radiation therapy in brain
metastases, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(13), 2529-36, July 2003
 - Herman MA, Tremont-Lukats I, Meyers CA, Trask DD, Froseth C, Renschler MF, Mehta MP, Neurocognitive and functional assessment of patients with brain
metastases: a pilot study, American Journal of Clinical Oncology : the Official Publication of the American Radium Society., 26(3), 273-9, June 2003
 - Shaw E, Scott C, Suh J, Kadish S, Stea B, Hackman J, Pearlman A, Murray K, Gaspar L, Mehta M, Curran W, Gerber M, RSR13 Plus Cranial Radiation Therapy in Patients With Brain Metastases:
Comparison With the Radiation Therapy Oncology Group Recursive
Partitioning Analysis Brain Metastases Database, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(12), 2364-71, June 2003
 - Jaeckle KA, Hess KR, Yung WK, Greenberg H, Fine H, Schiff D, Pollack IF, Kuhn J, Fink K, Mehta M, Cloughesy T, Nicholas MK, Chang S, Prados M, Phase II Evaluation of Temozolomide and 13-cis-Retinoic Acid for the
Treatment of Recurrent and Progressive Malignant Glioma: A North American
Brain Tumor Consortium Study, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(12), 2305-11, June 2003
 - Mackie TR, Kapatoes J, Ruchala K, Lu W, Wu C, Olivera G, Forrest L, Tome W, Welsh J, Jeraj R, Harari P, Reckwerdt P, Paliwal B, Ritter M, Keller H, Fowler J, Mehta M, Image guidance for precise conformal radiotherapy, International Journal of Radiation Oncology, Biology, Physics, 56(1), 89-105, May 2003
 - Grossman SA, O'Neill A, Grunnet M, Mehta M, et al, Phase III Study of Infusional Carmustine and, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 21(8), 1485-91, April 2003
 - Stieber VW, Bourland JD, Tome WA, Mehta MP, Gentlemen (and Ladies), Choose your Weapons: Gamma Knife vs. Linear
Accelerator Radiosurgery, Technol Cancer Res Treat, 2(2), 79-86, April 2003
 - Thomadsen B, Mehta M, Howard S, Das R, Craniospinal treatment with the patient supine, Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists., 28(1), 35-8, Spring 2003
 - Abrey LE, Mehta MP (Apr 2003) Treatment of brain metastases: a short review of current therapies and the
emerging role of temozolomide., Clin Adv Hematol Oncol, 1 (4), 231-6
 - Scrimger RA, Tome WA, Olivera GH, Reckwerdt PJ, Mehta MP, Fowler JF, Reduction in radiation dose to lung and other normal tissues using helical
tomotherapy to treat lung cancer, in comparison to conventional field
arrangements, American Journal of Clinical Oncology : the Official Publication of the American Radium Society., 26(1), 70-8, February 2003
 - Harari PM, Mehta MP, Ritter MA, Petereit DG, Clinical promise tempered by reality in the delivery of combined
chemoradiation for common solid tumors, Seminars in Radiation Oncology, 13(1), 3-12, January 2003
 - Sanghavi SN, Needle MN, Krailo MD, Geyer JR, Ater J, Mehta MP, A phase I study of topotecan as a radiosensitizer for brainstem glioma of
childhood: First report of the Children's Cancer Group-0952, Neuro-oncology, 5(1), 8-13, January 2003
 - Abrey L, Mehta MP, Treatment of Brain Metastases: A Short Review of Current Therapies and the Emerging Role of Temozolomide, Clinical Advances in Hematology and Oncology, 1, 231-238, 2003
- Mehta MP, Book Review: Controversies in Neuro-Oncology (Frontiers of Radiation Therapy and Oncology, Vol. 33), Edited by T. Wiegel, W. Hinkelbein, M. Brock, and T. Hoell. S. Karger, Basel, 1999, 380 pp., ISBN 3, NeuroOncology, 5, 221-222, 2003
- Yawn BP, Wollan PC, Schroeder C, Rocca L, Mehta M, Temporal Trends in Brain Metastases Associated with Breast and Lung Cancer, Minn Med, 86, 32-37, 2003
- Regine WF, Sperduto PW, Scott CB, Mehta MP, What is the appropriate primary end point for clinical trials for patients
with brain metastases? In Response to Drs. Burri and
Asher, International Journal of Radiation Oncology, Biology, Physics, 53(5), 1394, Aug 2002
- Mehta MP, Shapiro WR, Glantz MJ, Patchell RA, Weitzner MA, Meyers CA, Schultz CJ, Roa WH, Leibenhaut M, Ford J, Curran W, Phan S, Smith JA, Miller RA, Renschler MF, Lead-in phase to randomized trial of motexafin gadolinium and whole-brain
radiation for patients with brain metastases: centralized assessment of
magnetic resonance imaging, neurocognitive, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology., 20(16), 3445-53, Aug 2002
 - Welsh JS, Patel RR, Ritter MA, Harari PM, Mackie TR, Mehta MP, Helical tomotherapy: an innovative technology and approach to radiation
therapy, Technol Cancer Res Treat, 1(4), 311-6, Aug 2002
 - Patel RR, Mehta M, Three-dimensional Conformal Radiotherapy for Lung Cancer: Promises and
Pitfalls, Current Oncology Reports, 4(4), 347-53, July 2002
 - Packer RJ, Mehta M, Neurocognitive sequelae of cancer treatment, Neurology, 59(1), 8-10, July 2002
 - Sneed PK, Suh JH, Goetsch SJ, Sanghavi SN, Chappell R, Buatti JM, Regine WF, Weltman E, King VJ, Breneman JC, Sperduto PW, Mehta MP, A multi-institutional review of radiosurgery alone vs. radiosurgery with
whole brain radiotherapy as the initial management of brain
metastases, International Journal of Radiation Oncology, Biology, Physics, 53(3), 519-26, July 2002
 - Tome WA, Mehta MP, Meeks SL, Buatti JM, Fractionated stereotactic radiotherapy: a short review, Technol Cancer Res Treat, 1(3), 153-72, June 2002
 - Mehta M, Retrospective vs. randomized data: the prevalence of bias. in response to
Drs. Millar and Laperriere, International Journal of Radiation Oncology, Biology, Physics, 53(1), 252-3, May 2002
- Robins HI, Chang SM, Prados MD, Yung WK, Hess K, Schiff D, Greenberg H, Fink K, Nicolas K, Kuhn JG, Cloughesy T, Junck L, Mehta M, A phase II trial of thymidine and carboplatin for recurrent malignant
glioma: a North American Brain Tumor Consortium Study, Neuro-oncology, 4(2), 109-14, April 2002
 - Liu Z, Salamat MS, Hafez GR, Mehta MP, Robins HI, Amoli RS, Tomic S, Pineal sarcoma, Acta Neurochirurgica, 144(1), 89-92, January 2002
 - Robins HI, Liu G, Hayes L, Mehta M, Trastuzumab for breast cancer-related carcinomatous meningitis, 2(4), 316, January 2002
 - De Stasio G, Frazer BH, Gilbert B, Sobderegger B, Richter K, Salt C, P Casalbore, Howard S, Rajesh D, Fowler J, Mehta MP, R Pallini, Mercanti D., New criteria for GdNCT agents, Research and Development in Neutron Capture Therapy, 813-817, 2002
- Mehta M, Scrimger R, Mackie TR, Paliwal B, Chappell R, Fowler J, A New Approach to Dose Escalation in Non-Small Cell Lung Cancer. Biological and Physical Basis of IMRT and Tomotherapy, Procedings of the 6th International Conference on Dose, Time and Fractionation, 275-291, 2002
- Miranpuri AS, Tome WA, Paliwal BR, Kesslering C, Mehta MP, Assessment of patient-independent intrinsic error for a noninvasive frame
for fractionated stereotactic radiotherapy, International Journal of Cancer. Journal International Du Cancer, 96(5), 320-5, October 2001
 - Sanghavi SN, Miranpuri SS, Chappell R, Buatti JM, Sneed PK, Suh JH, Regine WF, Weltman E, King VJ, Goetsch SJ, Breneman JC, Sperduto PW, Scott C, Mabanta S, Mehta MP, Radiosurgery for patients with brain metastases: a multi-institutional
analysis, stratified by the RTOG recursive partitioning analysis
method, International Journal of Radiation Oncology, Biology, Physics, 51(2), 426-34, October 2001
 - Tome WA, Meeks SL, McNutt TR, Buatti JM, Bova FJ, Friedman WA, Mehta M, Optically guided intensity modulated radiotherapy, Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 61(1), 33-44, October 2001
 - Auchter RM, Scholtens D, Adak S, Wagner H, Cella DF, Mehta MP, Quality of life assessment in advanced non-small-cell lung cancer patients
undergoing an accelerated radiotherapy regimen: report of ECOG study 4593.
Eastern Cooperative Oncology Group, International Journal of Radiation Oncology, Biology, Physics, 50(5), 1199-206, August 2001
 - De Stasio G, Casalbore P, Pallini R, Gilbert B, Sanita F, Ciotti MT, Rosi G, Festinesi A, Larocca LM, Rinelli A, Perret D, Mogk DW, Perfetti P, Mehta MP, Mercanti D, Gadolinium in human glioblastoma cells for gadolinium neutron capture
therapy, Cancer Research, 61(10), 4272-7, May 2001
 - Carde P, Timmerman R, Mehta MP, Koprowski CD, Ford J, Tishler RB, Miles D, Miller RA, Renschler MF, Multicenter phase Ib/II trial of the radiation enhancer motexafin
gadolinium in patients with brain metastases, Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 19(7), 2074-83, April 2001
 - Schulz CA, Harari PM, Mehta MP, Multiple daily fractionation radiotherapy schedules in lung cancer, Current Oncology Reports, 3(2), 179-84, March 2001
 - Rao RD, Robins HI, Mehta MP, Late recurrence of a primitive neuro-ectodermal tumor, Oncology, 61(3), 189-91, 2001
 - Mehta M, Scrimger R, Mackie R, Paliwal B, Chappell R, Fowler J, A new approach to dose escalation in non-small-cell lung cancer, International Journal of Radiation Oncology, Biology, Physics, 49(1), 23-33, Jan 2001
 - Chang SM, Kuhn JG, Robins HI, Schold SC Jr, Spence AM, Berger MS, Mehta M, Pollack IF, Rankin C, Prados MD, A Phase II study of paclitaxel in patients with recurrent malignant glioma
using different doses depending upon the concomitant use of
anticonvulsants: a North American Brain Tumor Consort, Cancer, 91(2), 417-22, Jan 2001
 - Mehta M, Yung WK, Bullard D, Barger G, Choucair A, Gillin M, Grossman S, Guha A, Hammond ME, Michalski J, Prados M, Provins S, Scott C, Zamorano L, Radiation Therapy Oncology Group, Radiation Therapy Oncology Group. Research Plan 2002-2006. Brain Tumor
Committee, International Journal of Radiation Oncology, Biology, Physics, 51(3 Suppl 2), 11-8, 2001
 - Hammond ME, Ang K, Byhardt R, Campbell B, Chapman JD, Eisenberg B, Greven K, Harris J, Hoffman J, Lange C, McCormick B, Mehta M, Sandler H, Trotti A, Willet C, Wolfson A, Furness A, Jensen T, Grignon D, Okunieff P, Radiation Therapy Oncology Group, Radiation Therapy Oncology Group. Research Plan 2002-2006. Tumor
Utilization Committee, International Journal of Radiation Oncology, Biology, Physics, 51(3 Suppl 2), 103-9, 2001
 - Rao R, Robins HI, Mehta MP, An unusual case of liver metastases from GBM following radiosurgery, Journal of Radiosurgery, 3, 165-167, 2001
- Mehta MP, Book Review: Combined Modality Therapy of Central Nervous System Tumors. eds Brady, Heilmann and Molls, Springer, Berlin, Oncology, 61, 255-256, 2001
- Mehta MP, Tome WA, Olivera GH, Radiotherapy for brain tumors, Current Oncology Reports, 2(5), 438-44, September 2000
 - Gentry J, Steeves R, Paliwal B, Mehta M, Hartje S, The operational impact of a program to measure and monitor radiation dose
to external beam patients, The Journal of Oncology Management : the Official Journal of the American College of Oncology Administrators, 9(5), 10-5, 2000
 - Robins HI, Howard SP, Mehta MP, Validity of Datasets Questioned in Gliadel Study, Managed Care & Cancer, 10-11, July 2000
- Tome W, Mehta M, Paliwal B, From Roots to Realizations?Radiosurgery, Advance for Administrators in Imaging and Oncology, 10(7), 45-50, July 2000
- Mehta MP, The contemporary role of radiation therapy in the management of lung cancer, Surgical Oncology Clinics of North America, 9(3), 539-61 ix, July 2000
 - Gilbert M, O'Neill A, Grossman S, Grunnet M, Mehta M, Jubelirer S, Hellman R, A phase II study of preradiation chemotherapy followed by external beam
radiotherapy for the treatment of patients with newly diagnosed
glioblastoma multiforme: an Eastern Cooperative Onco, Journal of Neuro-oncology, 47(2), 145-52, April 2000
 - Schold SC Jr, Kuhn JG, Chang SM, Bosik ME, Robins HI, Mehta MP, Spence AM, Fulton D, Fink KL, Prados MD, A phase I trial of 1,3-bis(2-chloroethyl)-1-nitrosourea plus temozolomide:
a North American Brain Tumor Consortium study, Neuro-oncology, 2(1), 34-9, Jan 2000
 - Merchant JJ, Kim K, Mehta MP, Ripple GM, Larson ML, Brophy DJ, Hammes LC, Schiller JC, Pilot and Safety Trial of Carboplatin, Paclitaxel and Thalidomide in Advanced Non-Small Cell Lung Cancer, Lung Cancer, 2, 48-52, 2000
- Orth RC, Sinha P, Madsen EL, Frank G, Korosec FR, Mackie TR, Mehta MP, Development of a unique phantom to assess the geometric accuracy of magnetic resonance imaging for stereotactic localization., Neurosurgery, 45(6), 1423-9; discussion 1, December 1999
 - Boyd TS, Mehta MP, Stereotactic radiosurgery for brain metastases, Oncology, 13(10), 1397-409; discussion, October 1999
 - Robins HI, Tutsch K, Katschinski DM, Jacobson E, Mehta M, Olsen M, Cohen JD, Tiggelaar CL, Arzoomanian RZ, Alberti D, Feierabend C, Wilding G, Phase I trial of intravenous thymidine and carboplatin in patients with advanced cancer, Journal of Clinical Oncology, 17(9), 2922-31, September 1999
 - Mehta MP, Sanghavi S, Management trends for lung cancer, Wmj : Official Publication of the State Medical Society of Wisconsin, 98(4), 37-9 42, 1999
 - Corn BW, Mehta MP, Buatti JM, Wolfson AH, Greven KM, Kim RY, Dunton CJ, Loeffler JS, Stereotactic Irradiation: potential new treatment method for brain metastases resulting from ovarian cancer., American Journal of Clinical Oncology, 22(2), 143-6, April 1999
 - Mehta MP, Amifostine and combined-modality therapeutic approaches, Seminars in Oncology, 26(2 Suppl 7), 95-101, April 1999
 - Boyd TS, Mehta MP, Radiosurgery for brain metastases, Neurosurgery Clinics of North America, 10(2), 337-50, April 1999
 - Chang SM, Kuhn JG, Robins HI, Schold SC, Spence AM, Berger MS, Mehta MP, Bozik ME, Pollack I, Schiff D, Gilbert M, Rankin C, Prados MD, Phase II study of phenylacetate in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report, Journal of Clinical Oncology, 17(3), 984-90, March 1999
 - Mackie TR, Balog J, Ruchala K, Shepard D, Aldridge S, Fitchard E, Reckwerdt P, Olivera G, McNutt T, Mehta M, Tomotherapy, Seminars in Radiation Oncology, 9(1), 108-17, Jan 1999
 - Sanghavi S, Skrupsky R, Badie B, Robins H, Tome W, Mehta M, Recurrent malignant gliomas treated with radiosurgery, Journal of Radiosurgery, 2, 119-125, 1999
- Miranpuri SS, Schulz CA, Chappell RJ, Kesava PP, Nguyen PH, Olsen MA, McNutt TR, Mehta MP, Comparison of methods for response analysis of central nervous system neoplasms, Journal of Radiosurgery, 2, 153-162, 1999
- Gentry J, Boyd T, Mehta M, Use of digital technology improves patient documentation and decreases costs in radiation oncology, Journal of Oncology Management, 8, 10-13, 1999
- Mehta MP, Tannehill SP, Adak S, Martin L, Petereit DG, Wagner H, Fowler JF, Johnson D, Phase II trial of hyperfractionated accelerated radiation therapy for nonresectable non-small-cell lung cancer: results of Eastern Cooperative Oncology Group 4593, Journal of Clinical Oncology, 16(11), 3518-23, November 1998
 - Mehta MP, Protection of normal tissues from the cytotoxic effects of radiation therapy: focus on amifostine, Seminars in Radiation Oncology, 8(4 Suppl 1), 14-6, October 1998
 - Mehta MP, Protection of normal tissues from the cytotoxic effects of radiation therapy: Focus on amifostine, Seminars in Radiation Oncology, 8(4), 14-16, October 1998
- Chappell R, Miranpuri SS, Mehta MP, Dimension in defining tumor response [letter], Journal of Clinical Oncology, 16(3), 1234, March 1998
 - Kesava P, Mehta MP, MR demonstration of arterial thrombosis following radiosurgery for cerebral AVMs, Journal of Radiosurgery, 1, 291-295, 1998
- Chang SM, Kuhn JG, Rizzo J, Robins HI, Schold SC Jr, Spence AM, Berger MS, Mehta MP, Bozik ME, Pollack I, Gilbert M, Fulton D, Rankin C, Malec M, Prados MD, Phase I study of paclitaxel in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report., Journal of Clinical Oncology, 16(6), 2188-94, 1998
 - Mehta MP, Boyd T, Sinha P, The status of stereotactic radiosurgery for cerebral metastases in 1997., Journal of Radiosurgery, 1, 17-30, 1998
- Bastin KT, Mehta MP, Rogers P, Miles J, Gilchrest K, Spectrum of radiosurgically induced histopathologic changes correlated with radiographic changes,, Journal of Radiosurgery, 1, 201-211, 1998
- Mehta MP, Sinha P, Kanwar K, Inman A, Albanese M, Fahl W, A preliminary, controlled, randomized evaluation of the value of Internet-based oncologic teaching modules as an adjunct to traditional, medical school classroom teaching methods, Journal of Cancer Education, 13, 12-17, 1998
- Mehta MP, Sinha P, Kanwar K, Inman A, Albanese M, Fahl W, Evaluation of Internet-based oncologic teaching for medical students., Journal of Cancer Education, 13(4), 197-202, 1 Jan 1998
 - Mehta M, Noyes W, Craig B, Lamond J, Auchter R, French M, Johnson M, Levin A, Badie B, Robbins I, Kinsella T, A cost-effectiveness and cost-utility analysis of radiosurgery vs. resection for single-brain metastases., International Journal of Radiation Oncology, Biology, Physics, 39(2), 445-54, September 1997
 - Tannehill SP, Mehta MP, Larson M, Storer B, Pellet J, Kinsella TJ, Schiller JH, Effect of amifostine on toxicities associated with sequential chemotherapy and radiation therapy for unresectable non-small-cell lung cancer: results of a phase II trial., Journal of Clinical Oncology, 15(8), 2850-7, August 1997
 - Yao MS, Mehta MP, Boyett JM, Li H, Donahue B, Rorke LB, Zeltzer PM, The effect of M-stage on patterns of failure in posterior fossa primitive neuroectodermal tumors treated on CCG-921: a phase III study in a high-risk patient population., International Journal of Radiation Oncology, Biology, Physics, 38(3), 469-76, June 1997
 - Mehta MP, Kinsella TJ, What's new in radiation oncology., Wisconsin Medical Journal, 96(4), 42-9, April 1997
 - Mehta MP, External beam radiation therapy: an effective tool to manage painful bone metastases., Cancer Pain Update, 66, 3-4, 1997
- Lamond JP, Mehta MP, Boothman DA, The potential of topoisomerase I inhibitors in the treatment of CNS malignancies: report of a synergistic effect between topotecan and radiation., Journal of Neuro-oncology, 30(1), 1-6, October 1996
 - Kesava P, Baker E, Mehta M, Turski P, Staging of arteriovenous malformations using three-dimensional time-of-flight MR angiography and volume-rendered displays of surface anatomy., AJR American Journal of Roentgenology, 167(3), 605-9, September 1996
 - Kesava PP, Perl J, Mehta MP, Warner TF, Graves VB, Strother CM, Thorotrast-associated oropharyngeal hemorrhage: treatment by means of carotid occlusion with use of flow arrest and fibered coils., Journal of Vascular and Interventional Radiology (JVIR), 7(5), 709-12, 1996
 - Prados MD, Schold SC, Spence AM, Berger MS, McAllister LD, Mehta MP, Gilbert MR, Fulton D, Kuhn J, Lamborn K, Rector DJ, Chang SM, Phase II study of paclitaxel in patients with recurrent malignant glioma., Journal of Clinical Oncology, 14(8), 2316-21, August 1996
 - Thomas MA, Ryner LN, Mehta MP, Turski PA, Sorenson JA, Localized 2D J-resolved 1H MR spectroscopy of human brain tumors in vivo., Journal of Magnetic Resonance Imaging, 6(3), 453-9, 1996
 - Mehta MP, Kinsella TJ, Harari PM, Ritter MA, Mahler PA, Steeves RA, Stitt JA, Petereit DG, Manpower issues and training program directions in radiation oncology [letter], International Journal of Radiation Oncology, Biology, Physics, 34(4), 970, March 1996
 - Auchter R M, Lamond J P, Alexander E, Buatti J M, Chappell R, Friedman W A, Kinsella T J, Levin A B, Noyes W R, Schultz C J, Loeffler J S, Mehta M P, A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis, International Journal of Radiation Oncology, Biology, Physics, 35, 27-35, 1996
 - Tannehill S P, Mehta M P, Amifostine and radiation therapy: past, present, and future, Seminars In Oncology, 23, 69-77, 1996
 - Mehta M, Schiller JH, Prognosis with asymptomatic pulmonary nodules., Jama, 274(4), 358, July 1995
 - Masciopinto J E, Levin A B, Mehta M P, Rhode B S, Stereotactic radiosurgery for glioblastoma: a final report of 31 patients, Journal of Neurosurgery, 82, 530-5, 1995
 - Sarkaria J N, Mehta M P, Loeffler J S, Buatti J M, Chappell R J, Levin A B, Alexander E 3rd, Friedman W A, Kinsella T J, Radiosurgery in the initial management of malignant gliomas: survival comparison with the rtog recursive partitioning analysis radiation therapy oncology group, International Journal of Radiation Oncology, Biology, Physics, 32, 931-41, 1995
 - Mehta M P, The physical, biologic, and clinical basis of radiosurgery, Current Problems In Cancer, 19, 265-329, 1995
 - Mehta MP, Noyes WR, Mackie TR, Linear accelerator configurations for radiosurgery., Seminars in Radiation Oncology, 5, 203-212, 1995
- Mehta MP, Masciopinto J, Rozental J, Levin A, Chappell R, Bastin K, Miles J, Turski P, Kubsad S, Mackie T, et al, Stereotactic radiosurgery for glioblastoma multiforme: report of a prospective study evaluating prognostic factors and analyzing long-term survival advantage [see comments, International Journal of Radiation Oncology, Biology, Physics, 30(3), 541-9, 15 Oct 1994
 - Mehta MP, Glioblastoma multiforme: who should receive stereotactic boost therapy? [letter], International Journal of Radiation Oncology, Biology, Physics, 30(3), 746, October 1994
 - Larson DA, Bova F, Eisert D, Kline R, Loeffler J, Lutz W, Mehta M, Palta J, Schewe K, Schultz C, et al, Current radiosurgery practice: results of an ASTRO survey. Task Force on Stereotactic Radiosurgery, American Society for Therapeutic Radiology and Oncology., International Journal of Radiation Oncology, Biology, Physics, 28(2), 523-6, January 1994
 - Masciopinto JE, Levin AB, Mehta MP, Rhode BS, Stereotactic radiosurgery for glioblastoma multiforme., Stereotactic and Functional Neurosurgery, 63(1-4), 233-40, 1994
 - Larson DA, Bova FJ, Eisert D, Kline R, Loeffler JS, Lutz W, Mehta MP, Palta J, Schewe F, Schultz CJ, Shaw E, Wilson JF, Lunsford LD, Alexander E, Chapman P, Coffey R, Friedman W, Harsh G, Maciunas R, Olivier A, Steinberg G, Walsh J, Consensus statement on stereotactic radiosurgery quality improvement., International Journal of Radiation Oncology, Biology, Physics, 28, 527-530, 1994
- Lunsford LD, Alexander E, Chapman P, Coffey R, Friedman W, Harsh G, Maciunas R, Olivier A, Steinberg G, Walsh J, Larson DA, Bova FJ, Eisert D, Kline R, Loeffler JS, Lutz W, Mehta MP, Palta J, Schewe F, Schultz CJ, Shaw E, Wilson JF, Consensus statement on stereotactic radiosurgery quality improvement., Neurosurgery, 34, 193-195, 1994
- Auchter RM, Mehta MP, Peters NE, Kitchen R, Thomadsen BR, Kinsella TJ, An original technique for surface mold high dose rate brachytherapy for Kaposi's sarcoma of the penis., Endocurietherapy/Hyperthermia Oncology, 10, 193-198, 1994
- Mehta M P, Masciopinto J, Rozental J, Levin A, Chappell R, Bastin K, Miles J, Turski P, Kubsad S, Mackie T, Et Al, Stereotactic radiosurgery for glioblastoma multiforme: report of a prospective study evaluating prognostic factors and analyzing long-term survival advantage, International Journal of Radiation Oncology, Biology, Physics, 30, 541-9, 1994
 - Nag S, Abitbol AA, Anderson LL, Blasko JC, Flores A, Harrison LB, Hilaris BS, Martinez AA, Mehta MP, Nori D, et al, Consensus guidelines for high dose rate remote brachytherapy in cervical, endometrial, and endobronchial tumors.Clinical Research Committee, American Endocurietherapy Society., International Journal of Radiation Oncology, Biology, Physics, 27(5), 1241-4, December 1993
 - Petereit DG, Mehta MP, Buchler DA, Kinsella TJ, Inguinofemoral radiation of N0,N1 vulvar cancer may be equivalent to lymphadenectomy if proper radiation technique is used [see comments], International Journal of Radiation Oncology, Biology, Physics, 27(4), 963-7, November 1993
 - Mehta MP, Kinsella TJ, Cavernous sinus cranial neuropathies: is there a dose-response relationship following radiosurgery? [editorial; comment], International Journal of Radiation Oncology, Biology, Physics, 27(2), 477-80, September 1993
 - Bastin KT, Mehta MP, Kinsella TJ, Thoracic volume radiation sparing following endobronchial brachytherapy: a quantitative analysis., International Journal of Radiation Oncology, Biology, Physics, 25(4), 703-7, March 1993
 - Petereit DG, Mehta MP, Buchler DA, Kinsella TJ, A retrospective review of nodal treatment for vulvar cancer., American Journal of Clinical Oncology, 16(1), 38-42, February 1993
 - Mehta M P, Petereit D, Turski P, Gehring M, Levin A, Kinsella T, Magnetic resonance angiography: a three-dimensional database for assessing arteriovenous malformations technical note, Journal of Neurosurgery, 79, 289-93, 1993
 - Rozental JM, Cohen JD, Mehta MP, Levine RL, Hanson JM, Nickles RJ, Acute changes in glucose uptake after treatment: the effects of carmustine (BCNU) on human glioblastoma multiforme., Journal of Neuro-oncology, 15(1), 57-66, January 1993
 - Petereit D, Mehta M, Turski P, Levin A, Strother C, Mistretta C, Mackie R, Gehring M, Kubsad S, Kinsella T, Treatment of arteriovenous malformations with stereotactic radiosurgery employing both magnetic resonance angiography and standard angiography as a database., International Journal of Radiation Oncology, Biology, Physics, 25(2), 309-13, January 1993
 - Mehta MP, Petereit DG, Kubsad SS, Turski PA, Levin AB, Kinsella TJ, Radiosurgery for arteriovenous malformations based on magnetic resonance angiography., AMPI Medical Physics Bulletin, 18, 25-28, 1993
- Petereit DG, Mehta MP, Buchler DA, Kinsella TJ, :Groin node radiation for vulvar cancer: Treatment planning must do more than scratch the surface: Nodal control sustained at greater than 90% with 40 months median follow-up., International Journal of Radiation Oncology, Biology, Physics, 27, 991, 1993
- Bastin KT, Mehta MP, Meningeal hemangiopericytoma: defining the role for radiation therapy., Journal of Neuro-oncology, 14(3), 277-87, November 1992
 - Rieger J, Mehta M, Paliwal B, Kubsad S, Weight consideration in the use of cerrobend beam blocks., Medical Dosimetry, 17(3), 141-3, 1992
 - Bastin KT, Mehta MP, Lung cancer mortality in Wisconsin: year 2001., Wisconsin Medical Journal, 91(7), 343-7, July 1992
 - Mehta M P, Rozental J M, Levin A B, Mackie T R, Kubsad S S, Gehring M A, Kinsella T J, Defining the role of radiosurgery in the management of brain metastases, International Journal of Radiation Oncology, Biology, Physics, 24, 619-25, 1992
 - Mehta M, Petereit D, Chosy L, Harmon M, Fowler J, Shahabi S, Thomadsen B, Kinsella T, Sequential comparison of low dose rate and hyperfractionated high dose rate endobronchial radiation for malignant airway occlusion., International Journal of Radiation Oncology, Biology, Physics, 23(1), 133-9, 1992
 - Mehta MP, Endobronchial brachytherapy: Wither prescription point?, International Journal of Radiation Oncology, Biology, Physics, 23, 251, 1992
- Mehta MP, Bastin KT, Wiersma SR, Treatment of Wilms' tumour. Current recommendations., Drugs, 42(5), 766-80, November 1991
 - Rozental JM, Levine RL, Mehta MP, Kinsella TJ, Levin AB, Algan O, Mendoza M, Hanson JM, Schrader DA, Nickles RJ, Early changes in tumor metabolism after treatment: the effects of stereotactic radiotherapy., International Journal of Radiation Oncology, Biology, Physics, 20(5), 1053-60, May 1991
 - Bertelrud K, Mehta M, Shanahan T, Utrie P, Gehring M, Bellyboard device reduces small bowel displacement., Radiologic Technology, 62(4), 284-7, 1991
 - Gehring M A, Mackie T R, Kubsad S S, Paliwal B R, Mehta M P, Kinsella T J, A three-dimensional volume visualization package applied to stereotactic radiosurgery treatment planning, International Journal of Radiation Oncology, Biology, Physics, 21, 491-500, 1991
 - Shahabi S, Mehta MP, Kubsad SS, Robertson S, Giese WL, Technical modification of perineal templates to reduce rectal mucosal dose from pelvic interstitial brachytherapy., Endocurietherapy/Hyperthermia Oncology, 7, 57-61, 1991
- Mehta MP, Mackie TR, Levin AB, Gehring MA, Kubsad SS, Rozental JM, Kinsella TJ, Radiosurgery for brain metastases., Contemporary Oncology, 1, 12-19, 1991
- Mehta MP, Endobronchial irradiation: is HDR better?, International Journal of Radiation Oncology, Biology, Physics, 19(6), 1629, December 1990
 - Mehta MP, Kubsad SS, Fowler JF, Verma AK, Hsieh JT, Kinsella TJ, 90Y.B72.3 against pancreatic cancer: dosimetric and biological analysis., International Journal of Radiation Oncology, Biology, Physics, 19(3), 627-31, September 1990
 - Shanahan TG, Mehta MP, Bertelrud KL, Buchler DA, Frank LE, Gehring MA, Kubsad SS, Utrie PC, Kinsella TJ, Minimization of small bowel volume within treatment fields utilizing customized belly boards., International Journal of Radiation Oncology, Biology, Physics, 19(2), 469-76, August 1990
 - Frank LE, Rowley LA, Shanahan TG, Mehta MP, Third place 1989 Alpha Cradle Award winner. Technical aspects in the use of belly boards for small bowel minimization., Medical Dosimetry, 15(1), 13-6, March 1990
 - Mehta M, Shahabi S, Jarjour N, Steinmetz M, Kubsad S, Effect of endobronchial radiation therapy on malignant bronchial obstruction., Chest, 97(3), 662-5, March 1990
 - Kubsad S S, Mackie T R, Gehring M A, Misisco D J, Paliwal B R, Mehta M P, Kinsella T J, Monte carlo and convolution dosimetry for stereotactic radiosurgery, International Journal of Radiation Oncology, Biology, Physics, 19, 1027-35, 1990
 - Thomadsen BR, Shahabi S, Mehta MP, Buchler DA, Giese WL, Differential loadings of brachytherapy templates., Endocurietherapy/Hyperthermia Oncology, 6, 197-202, 1990
- Shahabi S, Mehta MP, Wiley Jr AL, Gehring MA, Olsen KJ, Vainio PA, Computed tomographic dosimetric planning for optimization of pelvic interstitial implants., Endocurietherapy/Hyperthermia Oncology, 6, 47-52, 1990
- Mehta MP, Shahabi S, Jarjour NN, Kinsella TJ, Endobronchial irradiation for malignant airway obstruction., International Journal of Radiation Oncology, Biology, Physics, 17(4), 847-51, October 1989
 - Mehta MP, Goetowski PG, Kinsella TJ, Radiation induced thyroid neoplasms 1920 to 1987: a vanishing problem?, International Journal of Radiation Oncology, Biology, Physics, 16(6), 1471-5, June 1989
 - Mehta MP, Langeland P, Bertelrud K, Adult Wilms' tumor. Role of combined modality treatment., Acta Oncologica, 28(5), 647-50, 1989
 - Mehta MP, Shahabi S, Thomadsen BR, Uehling D, Kinsella TJ, A three-dimensional model for treatment planning of interstitial implants., Endocurietherapy/Hyperthermia Oncology, 5, 227-230, 1989
- Mehta MP, Normal tissue response: summary. American Association of Physicists in Medicine Proceedings, 7, 154-157, 1989
- Shahabi S, Mehta MP, The role of computerized tomography in dosimetric evaluation of endobronchial implants., Endocurietherapy/Hyperthermia Oncology, 4, 187-191, 1988
- Wiley AL Jr, Wirtanen GW, Mehta MP, Ramirez G, Shahabi S, Treatment of probable subclinical liver metastases and gross pancreatic carcinoma with hepatic artery 5-fluorouracil infusion and radiation therapy., Acta Oncologica, 27(4), 377-81, 1988

Profile DetailsIndividual Expertise profile of Minesh Prafulchandra Mehta, Copyright Minesh Prafulchandra Mehta. © COS Expertise TM, 2008, ProQuest LLC All rights reserved. |