Maxine L. Linial

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Fred Hutchinson Cancer Research Center
Basic Sciences Division
MemberAppointed: 1983
University of Washington
School of Public Health and Community Medicine
Global Health
Research ProfessorAppointed: 2002
Fred Hutchinson Cancer Research Center
Basic Sciences Division
Interdisciplinary Research Training
Appointed: 1998
University of Washington
School of Medicine
Microbiology
Research ProfessorAppointed: 1988
Professional Headshot of Maxine L. Linial

Mailing Address

Division of Basic Sciences
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N.
Seattle, Washington 98109
United States

Contact Information

Phone: (206) 667-4442
Fax: (206) 667-5939
mlinial@fhcrc.org

Qualifications

B.S., Cornell University, Bacteriology.
Ph.D., Tufts University, Microbiology and Molecular Biology.

Expertise and Research Interests

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Other Expertise

Editorial Board of "Virology"
Editorial Board of "Journal of Virology"

Keywords

COS Keywords:

Genetics, Microbiology, Molecular Biology, Pathobiology, Retrovirus, Tissue Culture, Viral Infections, Virology.

Additional Terms:

Genetics, Microbiology, Molecular Biology, Viral Disease, Viral Replication, Viruses.

Memberships

American Association for the Advancement of Science
American Society for Microbiology
American Society for Virology

Honors and Awards

Fellow, American Association for the Advancement of Science (AAAS)

Publications

  • Lee EG, Linial ML (Aug 2008) The C-terminus of foamy retrovirus Gag contains determinants for encapsidation of Pol protein into virions., Journal of virology Abstract
  • Jones-Engel L, May CC, Engel GA, Steinkraus KA, Schillaci MA, Fuentes A, Rompis A, Chalise MK, Aggimarangsee N, Feeroz MM, Grant R, Allan JS, Putra A, Wandia IN, Watanabe R, Kuller L, Thongsawat S, Chaiwarith R, Kyes RC, Linial ML (Aug 2008) Diverse contexts of zoonotic transmission of simian foamy viruses in Asia., Emerging infectious diseases, 14 (8), 1200-8 Abstract
  • Life RB, Lee EG, Eastman SW, Linial ML (Jul 2008) Mutations in the amino terminus of foamy virus Gag disrupt morphology and infectivity but do not target assembly., Journal of virology, 82 (13), 6109-19 Abstract
  • Murray SM, Picker LJ, Axthelm MK, Hudkins K, Alpers CE, Linial ML (Jun 2008) Replication in a superficial epithelial cell niche explains the lack of pathogenicity of primate foamy virus infections., Journal of virology, 82 (12), 5981-5 Abstract
  • Jones-Engel L, Steinkraus KA, Murray SM, Engel GA, Grant R, Aggimarangsee N, Lee BP, May C, Schillaci MA, Somgird C, Sutthipat T, Vojtech L, Zhao J, Linial ML (Jul 2007) Sensitive assays for simian foamy viruses reveal a high prevalence of infection in commensal, free-ranging Asian monkeys., Journal of virology, 81 (14), 7330-7 Abstract
  • Roy J, Linial ML (May 2007) Role of the foamy virus Pol cleavage site in viral replication., Journal of virology, 81 (10), 4956-62 Abstract
  • Linial, M.L. (2007) Ch. 61:Foamy Viruses, Fields Virology, 5th Edition, Philadelphia, Lippincott Williams & Wilkins, 2245-2262 pages (bookchapter)
  • Yu SF, Eastman SW, Linial ML (Aug 2006) Foamy virus capsid assembly occurs at a pericentriolar region through a cytoplasmic targeting/retention signal in Gag., Traffic (Copenhagen, Denmark), 7 (8), 966-77 Abstract
  • Murray SM, Picker LJ, Axthelm MK, Linial ML (Jan 2006) Expanded tissue targets for foamy virus replication with simian immunodeficiency virus-induced immunosuppression., Journal of virology, 80 (2), 663-70 Abstract
  • Lee EG, Linial ML, Basic residues of the retroviral nucleocapsid play different roles in gag-gag and Gag-Psi RNA interactions, Journal of Virology, 78(16), 8486-95, August 2004 Abstract
  • Boyer PL, Stenbak CR, Clark PK, Linial ML, Hughes SH (Jun 2004) Characterization of the polymerase and RNase H activities of human foamy virus reverse transcriptase., Journal of virology, 78 (12), 6112-21 Abstract
  • Stenbak CR, Linial ML (Sep 2004) Role of the C terminus of foamy virus Gag in RNA packaging and Pol, Journal of Virology, 78 (17), 9423-30 Abstract
  • Rinke CS, Boyer PL, Sullivan MD, Hughes SH, Linial ML, Mutation of the catalytic domain of the foamy virus reverse transcriptase leads to loss of processivity and infectivity, Journal of Virology, 76(15), 7560-70, Aug 2002 Abstract
  • Meiering, C.D, Linial, M.L., Reactivation of a complex retrovirus is controlled by a molecular switch and is inhibited by a viral protein, Proceedings of the National Academy of Sciences (USA), 99:, 15130-15135, 2002
  • Eastman SW, Linial ML, Identification of a conserved residue of foamy virus Gag required for intracellular capsid assembly, Journal of Virology, 75(15), 6857-64, August 2001 Abstract
  • Meiering CD, Linial ML, Historical perspective of foamy virus epidemiology and infection, Clinical Microbiology Reviews, 14(1), 165-76, Jan 2001 Abstract
  • Meiering CD, Comstock KE, Linial ML, Multiple integrations of human foamy virus in persistently infected human erythroleukemia cells, Journal of Virology, 74(4), 1718-26, February 2000 Abstract
  • Linial, M.L., Why aren't foamy viruses pathogenic?, Trends in Microbiology, 8, 284-289, 2000
  • Linial ML, Foamy viruses are unconventional retroviruses, Journal of Virology, 73(3), 1747-55, March 1999 Abstract

Profile Details

Last Updated: 6/1/2009

COS Expertise ID #120002
Reference this profile directly: http://myprofile.cos.com/mlinial