Margaret M. Madeleine

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Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Program in Epidemiology
Assistant MemberAppointed: 2008
University of Washington
School of Public Health and Community Medicine
Epidemiology
Assistant Research Professor
Professional Headshot of Margaret M. Madeleine

Mailing Address

1100 Fairview Ave. N
M4-C308
Seattle, Washington 98109-1024
United States

Contact Information

Phone: (206) 667-4630
mmadelei@fhcrc.org

Qualifications

Ph.D., University of Washington, Epidemiology, 1996.
M.P.H., Yale University, Epidemiology, 1991.

Expertise and Research Interests

My major research focus is on the molecular epidemiology of pathogens and our immune response to them that may be associated with cancer development and prognosis. I am also interested in the role that chronic subclinical immune disregulation (such as occurs with age, obesity, physical inactivity, hormone fluctuation, and UV exposure) and sex differences may play in carcinogenesis.

Keywords

COS Keywords:

Cancer Or Carcinogenesis, Epidemiology, Obesity.

Funding Received

  • National Cancer Institute: Inflammation Pathways in Breast Cancer, 2007 to 2011.
  • National Cancer Institute: Skin Cancer after Organ Transplant, 2007 to 2012.

Publications

  • Carter JJ, Paulson KG, Wipf GC, Miranda D, Madeleine MM, Johnson LG, Lemos BD, Lee S, Warcola AH, Iyer JG, Nghiem P, Galloway DA (2009) Association of Merkel Cell Polyomavirus-Specific Antibodies With Merkel Cell Carcinoma, Journal of the National Cancer Institute, 101, 1510-1522
  • Maley SN, Schwartz SM, Johnson LG, Malkki M, Du Q, Daling JR, Li SS, Zhao LP, Petersdorf EW, Madeleine MM (2009) Genetic variation in CXCL12 and risk of cervical carcinoma: a population-based case-control study, International journal of immunogenetics, 36, 367-375
  • Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna SM, Ciotti M, Das BR, Del Mistro A, Dybikowska A, Giuliano AR, Gudleviciene Z, Gyllensten U, Haws AL, Helland A, Herrington CS, Hildesheim A, Humbey O, Jee SH, Kim JW, Madeleine MM, Menczer J, Ngan HY, Nishikawa A, Niwa Y, Pegoraro R, Pillai MR, Ranzani G, Rezza G, Rosenthal AN, Roychoudhury S, Saranath D, Schmitt VM, Sengupta S, Settheetham-Ishida W, Shirasawa H, Snijders PJ, Stoler MH, Suárez-Rincón AE, Szarka K, Tachezy R, Ueda M, van der Zee AG, von Knebel Doeberitz M, Wu MT, Yamashita T, Zehbe I, Blettner M (2009) TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies, The Lancet Oncology, 10 (8), 772-784
  • Bodelon C, Madeleine MM, Voigt LF, Weiss NS (2009) Is the incidence of invasive vulvar cancer increasing in the United States?, Cancer Causes and Control, 20, 1779-1782
  • Chaturvedi AK, Madeleine MM, Biggar RJ, Engels EA (2009) Risk of Human Papillomavirus-Associated Cancers Among Persons With AIDS, Journal of the National Cancer Institute, 101, 1120-1130
  • Edelstein ZR, Madeleine MM, Hughes JP, Johnson LG, Schwartz SM, Galloway DA, Carter JJ, Koutsky LA (2009) Age of diagnosis of squamous cell cervical carcinoma and early sexual experience, Cancer Epidemiology, Biomarkers and Prevention, 18 (4), 1070-6
  • De Vuyst H, Clifford GM, Nascimento MC, Madeleine MM, Franceschi S (2009) Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis, International Journal of Cancer, 124 (7), 1626-36
  • Lanoy E, Dores GM, Madeleine MM, Toro JR, Fraumeni JF, Engels EA (2009) Epidemiology of nonkeratinocytic skin cancers among persons with AIDS in the United States, AIDS, 23 (3), 385-93
  • Insinga RP, Liaw KL, Johnson LG, Madeleine MM (2008) A systematic review of the prevalence and attribution of human papillomavirus types among cervical, vaginal, and vulvar precancers and cancers in the United States, Cancer Epidemiology, Biomarkers, and Prevention, 17 (7), 1611-22
  • Hussain SK, Madeleine MM, Johnson LG, Du Q, Malkki M, Wilkerson HW, Farin FM, Carter JJ, Galloway DA, Daling JR, Petersdorf EW, Schwartz SM (2008) Cervical and Vulvar Cancer Risk in Relation to the Joint Effects of Cigarette Smoking and Genetic Variation in Interleukin 2, Cancer Epidemiology, Biomarkers and Prevention, 17 (7), 1790-1799
  • Madeleine, MM, Johnson, LG, Smith, AG (2008) Comprehensive Analysis of HLA Class A, B, C, DRB1, and DQB1 Allele Associations with Cervical Cancer in a Population-Based Study, Cancer Research, 68, 3532-9
  • McDougall JA, Madeleine MM, Daling JR, Li CI (2007) Racial and ethnic disparities in cervical cancer incidence rates in the United States, 1992-2003, Cancer Causes and Control, 18 (10), 1175-86
  • Yu KJ, Bashirova A, Madeleine MM, Cheng J, Johnson LG, Schwartz SM, Carrington M, Hildesheim A (Nov 2007) Evaluation of the association with cervical cancer of polymorphisms in syndecan-1, a heparan sulfate proteoglycan involved with viral cell entry, Cancer Epidemiology, Biomarkers and Prevention, 16 (11), 2504-8
  • Madeleine, MM, Anttila, T, Schwartz, SM (2007) Risk of cervical cancer associated with Chlamydia trachomatis antibodies by histology, HPV type, and HPV cofactors, International Journal of Cancer, 120, 650-5
  • Carter JJ, Wipf GC, Madeleine MM, Schwartz SM, Koutsky LA, Galloway DA (2006) Identification of human papillomavirus type 16 L1 surface loops required for neutralization by human sera, Journal of Virology, 80 (10), 4664-72
  • Daling JR, Madeleine MM, Johnson LG, Schwartz SM, Shera KA, Wurscher MA, Carter JJ, Porter PL, Galloway DA, McDougall JK (Jul 2004) Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer, Cancer, 101 (2), 270-80
  • Johnson LG, Madeleine MM, Newcomer LM, Schwartz SM, Daling JR (Jul 2004) Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973-2000, Cancer, 101 (2), 281-8
  • Carter JJ, Madeleine MM, Wipf GC, Garcea RL, Pipkin PA, Minor PD, Galloway DA (Oct 2003) Lack of serologic evidence for prevalent simian virus 40 infection in humans, Journal of the National Cancer Institute, 95 (20), 1522-30
  • Coker AL, Bond S, Madeleine MM, Luchok K, Pirisi L (2003) Psychosocial stress and cervical neoplasia risk, Psychosomatic Medicine, 65 (4), 644-651
  • Madeleine, MM, Brumback, B, Cushing-Haugen (2002) Human Leukocyte Antigen Class II Alleles and Cervical Cancer Risk: A Population-Based Study, Journal of Infectious Diseases, 186, 1565-74
  • Schwartz SM, Daling JR, Shera KA, Madeleine MM, McKnight B, Galloway DA, Porter PL, McDougall JK (2001) Human papillomavirus and prognosis of invasive cervical cancer: a population-based study, Journal of Clinical Oncology, 19 (7), 1906-15
  • Madeleine, MM, Daling, JR, Carter, JJ, Et Al., (1997) Cofactors with human papillomavirus in a population-based study of vulvar cancer, Journal of the National Cancer Institute, 89, 1516-23
  • Madeleine MM, Wiktor SZ, Goedert JJ, Manns A, Levine PH, Biggar RJ, Blattner WA (1993) HTLV-I and HTLV-II world-wide distribution: reanalysis of 4,832 immunoblot results, International Journal of Cancer, 54 (2), 255-60

Profile Details

Last Verified: 1/8/2010

COS Expertise ID #1302860
Reference this profile directly: http://myprofile.cos.com/mmadelei