Dr. Marc Patrick Pelletier

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New Brunswick Heart Centre
Department of Cardiac Surgery
Clinical Department HeadAppointed: 2007
Professional Headshot of Marc Patrick Pelletier

Mailing Address

Clinical Department Head, Cardiac Surgery
New Brunswick Heart Centre
PO Box 2100
Saint John, New Brunswick E2L4L2
Canada

Contact Information

Phone: (506) 648-6102
Fax: (506) 648-6110
Pager: (506) 648-6111
pelma@reg2.health.nb.ca

Qualifications

Fellowship, Stanford University, Cardiothoracic Surgery & Transplantation, 2001.
M.Sc., McGill University, Experimental Surgery, 2000.
Residency Program, McGill University, Cardiac Surgery, 2000.
M.D., Dalhousie University, 1994.
B.Sc., Mount Allison University, Chemistry, 1990.

Expertise and Research Interests

Academic Cardiothoracic Surgery
Cardiothoracic Transplantation (Adult & Pediatric)
Ventricular Assist Devices
Berlin Heart
Teaching, Department of Cardiothoracic Surgery

Research
- Basic: mesenchymal stem cells (principles of migration and cytokine factor expression), MSC chemotaxis, cardiac regeneration and angiogenesis by MSC injection
- Clinical: Berlin Heart VAD, SPY intraoperative angiography, LV hypertrophy and transplant

Surgeries & Procedures:
Aortic surgery
Arterial Coronary Revascularization, Complete
Intraoperative Graft Assessment
SPY System
MediStim Flow Probe
Mitral Valve Repair
Aortic Valve Surgery

Other Expertise

FRCSC (Fellow of the Royal College of Surgeons of Canada)

Future Research

Mechanisms of mesenchymal stem cell migration
Improving survival of MSCs by transfection with cytokine(s)
Inhaled versus oral immunosupressants
Inhibition of CXCR3
Use of alterases in cardiopulmonary bypass

Industrial Relevance

Cardiac regeneration may eventually become a clinical reality, especially for patients who suffer from congestive heart failure. Such patients have few options, and many more are predicted to be diagnosed in the coming decade. Current methods of cellular differentiation and growth make possible the administration of a large numbers of cells. However, mechanisms are unclear and ongoing knowledge searches these, while giving others. This is especially so in an era aimed at minimizing surgical trauma, which has included a move towards lesser degrees of invasion. Pills, patches and injections are a logical progression from the current trend spanning surgery to catheter-based interventions.

Keywords

COS Keywords:

Congestive Heart Failure, Education, Organ Transplantation, Thoracic or Cardiovascular Surgery.

Additional Terms:

Cardiac Surgery, Cellular Cardiomyoplasty, Heart Failure, Heart Transplantation, Lung Transplantation.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
French: (Fluent, Fluent, Fluent)

Memberships

Association of Academic Surgery
Canadian Cardiovascular Society
International Society for Heart and Lung Transplantation
Society of Thoracic Surgeons

Previous Positions

2004-2007, Director, Stanford University, School of Medicine, Cardiothoracic Surgery, Stanford Cardiothoracic Surgery at El Camino Hospital
2001-2004, Assistant Professor, University of Toronto, Faculty of Medicine, Surgery, Cardiovascular Medicine

Funding Received

  • Rx&D Health Research Foundation - Supervisor: , $5,048, May 2003 to Aug 2003.
  • Schulich Heart Centre: , $90,000, Jul 2001 to Jan 2004.
  • Sunnybrook Research Institute: , $50,000, Jul 2001 to Jun 2003.
  • Physicians' Services Incorporated Foundation: Intraoperative patency assessment of vascular anastomoses., $158,000, Aug 2003 to Jul 2005.
  • University of Toronto, Dean's Fund: The influence of post-myocardial infarction cytokines on marrow stromal cell transmigration., $9,968, to .

Publications

  • Pelletier M, Mitchell S, Thoracic endovascular stent grafts., The Canadian Journal of Cardiology, 21(2), 179-80, Feb 2005 Abstract
  • Pelletier M, Mitchell S, Thoracic endovascular stent grafts., The Canadian Journal of Cardiology, 21(2), 179-80, Feb 2005 Abstract
  • Pelletier M, Mitchell S, Thoracic endovascular stent grafts., The Canadian Journal of Cardiology, 21(2), 179-80, Feb 2005 Abstract
  • Pelletier MP, Coady M, Ahmed S, Lamb J, Reitz BA, Robbins RC (Jan 2005) Successful repair of tracheal dehiscence after heart-lung transplantation., The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation., 24 (1), 99-101 Abstract
  • Desai ND, Pelletier MP, Mallidi HR, Christakis GT, Cohen GN, Fremes SE, Goldman BS (Sep 2004) Why is off-pump coronary surgery uncommon in Canada? Results of a population-based survey of Canadian heart surgeons., Circulation, 110 (11 Suppl 1), II7-12 Abstract
  • Desai ND, Pelletier MP, Mallidi HR, Christakis GT, Cohen GN, Fremes SE, Goldman BS (Sep 2004) Why is off-pump coronary surgery uncommon in Canada? Results of a population-based survey of Canadian heart surgeons., 110 (11 Suppl 1), II7-12 Abstract
  • Mallidi HR, Pelletier MP, Lamb J, Desai N, Sever J, Christakis GT, Cohen G, Goldman BS, Fremes SE (Mar 2004) Late outcomes in patients with uncorrected mild to moderate mitral regurgitation at the time of isolated coronary artery bypass grafting., The Journal of Thoracic and Cardiovascular Surgery, 127 (3), 636-44 Abstract
  • Mallidi HR, Pelletier MP, Lamb J, Desai N, Sever J, Christakis GT, Cohen G, Goldman BS, Fremes SE (Mar 2004) Late outcomes in patients with uncorrected mild to moderate mitral regurgitation at the time of isolated coronary artery bypass grafting., 127 (3), 636-44 Abstract
  • Fazel S, Borger MA, Weisel RD, Cohen G, Pelletier MP, Rao V, Yau TM (Jul-Aug 2004) Myocardial protection in reoperative coronary artery bypass grafting:., Journal of Cardiac Surgery, 19 (4), 291-5 Abstract
  • Fazel S, Borger MA, Weisel RD, Cohen G, Pelletier MP, Rao V, Yau TM (Jul-Aug 2004) Myocardial protection in reoperative coronary artery bypass grafting:., 19 (4), 291-5 Abstract
  • Fazel S, Mallidi HR, Pelletier MP, Sever JY, Christakis GT, Goldman BS, Fremes SE, Radial artery use is safe in patients with moderate to severe left ventricular dysfunction, The Annals of Thoracic Surgery, 75(5), 1414-21, May 2003 Abstract
  • Pelletier MP, Coady M, Macha M, Oyer PE, Robbins RC, Coronary atherosclerosis in cardiac transplant patients treated with total lymphoid irradiation, The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation., 22(2), 124-9, February 2003 Abstract
  • Pelletier MP, Chang CP, Vagelos R, Robbins RC, Alternative approach for use of a left ventricular assist device with a thrombosed prosthetic valve, The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation., 21(3), 402-4, March 2002 Abstract
  • Pelletier MP, Al-Khaldi AA, Berry GJ, Morin JF, Paraplegia after routine cardiac surgery: A rare complication, Journal of Cardiac Surgery, 410-2, 2002
  • Saito T, Pelletier MP, Shennib H, Giaid A, Nitric oxide system in needle-induced transmyocardial revascularization, The Annals of Thoracic Surgery, 72(1), 129-36, July 2001 Abstract
  • Pelletier MP, Edwardes MD, Michel RP, Halwani F, Morin JE, Prognostic markers in resectable non-small cell lung cancer: a multivariate analysis, Canadian Journal of Surgery. Journal Canadien De Chirurgie, 44(3), 180-8, June 2001 Abstract
  • Tchervenkov CI, Pelletier MP, Shum-Tim D, Beland MJ, Rohlicek C, Primary repair minimizing the use of conduits in neonates and infants with tetralogy or double-outlet right ventricle and anomalous coronary arteries, Journal of Thoracic and Cardiovascular Surgery, 119(2), 314-23, February 2000 Abstract
  • Shum-Tim D, Pelletier MP, Latter DA, De Varennes BE, Morin JE, Transplantation versus coronary artery bypass in patients with severe ventricular dysfunction. Surgical outcome and quality of life, Journal of Cardiovascular Surgery, 40(6), 773-80, December 1999 Abstract
  • Chu VF, Giaid A, Kuang JQ, McGinn AN, Li CM, Pelletier MP, Chiu RC, Thoracic Surgery Directors Association Award. Angiogenesis in transmyocardial revascularization: comparison of laser versus mechanical punctures, The Annals of Thoracic Surgery, 68(2), 301-7; discussion 30, August 1999 Abstract
  • Seely AJ, Pelletier MP, Snell LS, Trudel JL, Do surgical residents rated as better teachers perform better on in-training examinations?, American Journal of Surgery, 177(1), 33-7, Jan 1999 Abstract
  • Dorfman J, Duong M, Zibaitis A, Pelletier MP, Shum-Tim D, Li C, Chiu RC, Myocardial tissue engineering with autologous myoblast implantation, Journal of Thoracic and Cardiovascular Surgery, 116(5), 744-51, November 1998 Abstract
  • Pelletier MP, Giaid A, Sivaraman S, Dorfman J, Li CM, Philip A, Chiu RC, Angiogenesis and growth factor expression in a model of transmyocardial revascularization, The Annals of Thoracic Surgery, 66(1), 12-8, July 1998 Abstract
  • Pelletier MP, Solymoss S, Lee A, Chiu RC, Negative reexploration for cardiac postoperative bleeding: can it be therapeutic?, The Annals of Thoracic Surgery, 65(4), 999-1002, April 1998 Abstract

Profile Details

Last Updated: 10/15/2007

COS Expertise ID #913912
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