Fred Hutchinson Cancer Research Center Public Health Sciences Division Full Member University of Washington School of Public Health and Community Medicine Epidemiology Professor/Adjunct Professor | |
QualificationsPh.D., Johns Hopkins University, 1973. M.D., Bombay University, 1965. M.B.B.S., Bombay University, 1965. Expertise and Research InterestsMy expertise is in the following areas:cancer epidemiology;development of quantitative methodology. KeywordsCOS Keywords:Cancer Or Carcinogenesis, Epidemiology.Additional Terms:Cancer Epidemiology, Development of Quantitative Methodology.Honors and Awards2000, Distinguished Achievement Award,
Society for Risk Analysis
1990, Founders Award,
CIIT Institutes for Health Research
1977, Lester R. Ford Award,
Mathematical Association of America
Previous Positions1980-1984, Adjunct Associate Professor,
University of Pennsylvania,
School of Medicine,
Department of Research Medicine
1979-1984, Research Physician,
Fox Chase Cancer Center,
Institute for Cancer Research
1977-1984, Epidemiologist,
Fox Chase Cancer Center
1977-1984, Associate,
American Oncologic Hospital, Philidelphia
1977-1984, Member,
University of Pennsylvania,
Graduate Group in Epidemiology
1977-1980, Clinical Assistant Professor,
University of Pennsylvania,
School of Medicine,
Department of Research Medicine
1974-1976, Faculty Research Fellowship,
Indiana University Bloomington
1973-1977, Assistant Professor of Mathematics,
Indiana University Bloomington
1972-1973, Instructor in Mathematics,
Johns Hopkins University
Publications- Dewanji A, Luebeck EG, Moolgavkar SH (Oct 2005) A generalized Luria-Delbruck model., Mathematical Biosciences, 197 (2), 140-52
 - Meza R, Luebeck EG, Moolgavkar SH (Oct 2005) Gestational mutations and carcinogenesis., Mathematical Biosciences, 197 (2), 188-210
 - Clements MS, Armstrong BK, Moolgavkar SH (Oct 2005) Lung cancer rate predictions using generalized additive models., Biostatistics (oxford, England), 6 (4), 576-89
 - Moolgavkar SH (Jun 2005) A review and critique of the EPA's rationale for a fine particle standard., Regulatory Toxicology and Pharmacology : Rtp, 42 (1), 123-44
 - Hazelton WD, Clements MS, Moolgavkar SH (May 2005) Multistage carcinogenesis and lung cancer mortality in three cohorts., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 14 (5), 1171-81
 - Luebeck EG, Buchmann A, Schneider D, Moolgavkar SH, Schwarz M (Feb 2005) Modulation of liver tumorigenesis in Connexin32-deficient mouse., Mutation Research, 570 (1), 33-47
 - Moolgavkar SH (Dec 2004) Commentary: Fifty years of the multistage model: remarks on a landmark
paper., International Journal of Epidemiology, 33 (6), 1182-3
 - Little MP, Blettner M, Boice JD Jr, Bridges BA, Cardis E, Charles MW, de Vathaire F, Doll R, Fujimoto K, Goodhead DT, Grosche B, Hall P, Heidenreich WF, Jacob P, Moolgavkar SH, Muirhead CR, Niwa O, Paretzke HG, Richardson RB, Samet JM, Sasaki Y, Shore RE, Straume T, Wakeford R, Funding crisis at the Radiation Effects Research Foundation, Journal of Radiological Protection : Official Journal of the Society for Radiological Protection, 24(3), 195-7, Sep 2004
- Little MP, Blettner M, Boice JD Jr, Bridges BA, Cardis E, Charles MW, de Vathaire F, Doll R, Fujimoto K, Goodhead D, Grosche B, Hall P, Heidenreich WF, Jacob P, Moolgavkar SH, Muirhead CR, Niwa O, Paretzke HG, Richardson RB, Samet JM, Sasaki Y, Shore RE, Straume T, Wakeford R (Aug 2004) Potential funding crisis for the Radiation Effects Research Foundation., Lancet, 364 (9434), 557-8
 - Heidenreich WF, Luebeck EG, Hazelton WD, Paretzke HG, Moolgavkar SH, Response to the commentary of Donald A. Pierce (Radiat. Res. 160, 718-723,
2003), Radiation Research, 161(3), 369-70; author reply, Mar 2004
- Curtis SB, Hazelton WD, Luebeck EG, Moolgavkar SH (2004) From mechanisms to risk estimation--bridging the chasm., Advances in Space Research : the Official Journal of the Committee On Space Research (cospar)., 34 (6), 1404-9
 - Heidenreich WF, Luebeck EG, Moolgavkar SH (Jan 2004) Effects of exposure uncertainties in the TSCE model and application to the
Colorado miners data., Radiation Research, 161 (1), 72-81
 - Moolgavkar SH, Luebeck EG (Dec 2003) Multistage carcinogenesis and the incidence of human cancer., Genes, Chromosomes & Cancer, 38 (4), 302-6
 - Moolgavkar SH (Aug 2003) Air pollution and daily mortality in two U.S. counties: season-specific
analyses and exposure-response relationships., Inhalation Toxicology, 15 (9), 877-907
 - Krewski D, Zielinski JM, Hazelton WD, Garner MJ, Moolgavkar SH (2003) The use of biologically based cancer risk models in radiation
epidemiology., Radiation Protection Dosimetry, 104 (4), 367-76
 - Heidenreich WF, Luebeck EG, Hazelton WD, Paretzke HG, Moolgavkar SH (Nov 2002) Multistage models and the incidence of cancer in the cohort of atomic bomb
survivors., Radiation Research, 158 (5), 607-14
 - Dewanji A, Moolgavkar SH (Nov 2002) Choice of stratification in Poisson process analysis of recurrent event
data with environmental covariates., Statistics in Medicine, 21 (22), 3383-93
 - Luebeck EG, Moolgavkar SH (Nov 2002) Multistage carcinogenesis and the incidence of colorectal cancer., Proceedings of the National Academy of Sciences of the United States of America., 99 (23), 15095-100
 - Gregori G, Hanin L, Luebeck G, Moolgavkar S, Yakovlev A (Jan 2002) Testing goodness of fit for stochastic models of carcinogenesis., Mathematical Biosciences, 175 (1), 13-29
 - Curtis SB, Luebeck EG, Hazelton WD, Moolgavkar SH (2002) A new perspective of carcinogenesis from protracted high-LET radiation
arises from the two-stage clonal expansion model., Advances in Space Research : the Official Journal of the Committee On Space Research (cospar)., 30 (4), 937-44
 - Moolgavkar SH, Brown RC, Turim J (Sep 2001) Biopersistence, fiber length, and cancer risk assessment for inhaled
fibers., Inhalation Toxicology, 13 (9), 755-72
 - Hazelton WD, Luebeck EG, Heidenreich WF, Moolgavkar SH (Jul 2001) Analysis of a historical cohort of Chinese tin miners with arsenic, radon,
cigarette smoke, and pipe smoke exposures using the biologically based
two-stage clonal expansion model., Radiation Research, 156 (1), 78-94
 - Moolgavkar SH, Turim J, Brown RC (Jun 2001) The power of the European Union protocol to test for carcinogenicity of
inhaled fibers., Regulatory Toxicology and Pharmacology : Rtp, 33 (3), 350-5
 - Moolgavkar SH, Turim J, Brown RC, Luebeck EG (Apr 2001) Long man-made fibers and lung cancer risk., Regulatory Toxicology and Pharmacology : Rtp, 33 (2), 138-46
 - Curtis SB, Luebeck EG, Hazelton WD, Moolgavkar SH (2001) The role of promotion in carcinogenesis from protracted high-LET exposure., Physica Medica : Pm : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (aifb)., 17 Suppl 1, 157-60
 - Luebeck EG, Curtis SB, Hazelton WD, Moolgavkar SH (Dec 2000) The importance of promotion in lung carcinogenesis for protracted
exposures to radon and radon progeny., Radiation Research, 154 (6), 730;discussion 730-1
 - Moolgavkar SH (Dec 2000) Multistage models and the A-bomb survivor data: implications for
carcinogenic mechanisms?, Radiation Research, 154 (6), 728-9;discussion 730
 - Moolgavkar SH, Consideration of copollutants, Science, 290(5491), 453, Oct 2000
- Luebeck EG, Buchmann A, Stinchcombe S, Moolgavkar SH, Schwarz M (Aug 2000) Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on initiation and promotion
of GST-P-positive foci in rat liver: A quantitative analysis of
experimental data using a stochastic model., Toxicology and Applied Pharmacology, 167 (1), 63-73
 - Moolgavkar SH (Aug 2000) Air pollution and daily mortality in three U.S. counties., Environmental Health Perspectives, 108 (8), 777-84
 - Moolgavkar SH (Jul 2000) Air pollution and hospital admissions for diseases of the circulatory
system in three U.S. metropolitan areas., Journal of the Air & Waste Management Association (1995), 50 (7), 1199-206
 - Moolgavkar SH, Luebeck EG, Turim J, Brown RC (Feb 2000) Lung cancer risk associated with exposure to man-made fibers., Drug and Chemical Toxicology, 23 (1), 223-42
 - Moolgavkar SH (2000) Air pollution and hospital admissions for chronic obstructive pulmonary
disease in three metropolitan areas in the United States., Inhalation Toxicology, 12 Suppl 4, 75-90
 - Luebeck EG, Heidenreich WF, Hazelton WD, Paretzke HG, Moolgavkar SH (Oct 1999) Biologically based analysis of the data for the Colorado uranium miners
cohort: age, dose and dose-rate effects., Radiation Research, 152 (4), 339-51
 - Moolgavkar SH, Luebeck EG, Turim J, Hanna L (Aug 1999) Quantitative assessment of the risk of lung cancer associated with
occupational exposure to refractory ceramic fibers., Risk Analysis : an Official Publication of the Society for Risk Analysis, 19 (4), 599-611
 - Moolgavkar S, Woodward A, Krewski D, Cardis E, Zeise L (1999) Future perspectives, unresolved issues and research needs., Iarc Scientific Publications (131), 305-22
 - Dewanji A, Goddard MJ, Krewski D, Moolgavkar SH (Jan 1999) Two stage model for carcinogenesis: number and size distributions of
premalignant clones in longitudinal studies., Mathematical Biosciences, 155 (1), 1-12
 - Moolgavkar SH, Moller H, Woodward A (1999) Principles of the epidemiological approach to QEP., Iarc Scientific Publications (131), 61-73
 - Moolgavkar S, Krewski D, Schwarz M (1999) Mechanisms of carcinogenesis and biologically based models for estimation
and prediction of risk., Iarc Scientific Publications (131), 179-237
 - Moolgavkar SH, Luebeck EG, Anderson EL (Dec 1998) Estimation of unit risk for coke oven emissions., Risk Analysis : an Official Publication of the Society for Risk Analysis, 18 (6), 813-25
 - Kai M, Luebeck EG, Moolgavkar SH (Oct 1997) Analysis of the incidence of solid cancer among atomic bomb survivors
using a two-stage model of carcinogenesis., Radiation Research, 148 (4), 348-58
 - Moolgavkar SH, Luebeck EG, Anderson EL (Jul 1997) Air pollution and hospital admissions for respiratory causes in
Minneapolis-St. Paul and Birmingham., Epidemiology (cambridge, Mass.), 8 (4), 364-70
 - Heidenreich WF, Luebeck EG, Moolgavkar SH (Jun 1997) Some properties of the hazard function of the two-mutation clonal
expansion model., Risk Analysis : an Official Publication of the Society for Risk Analysis, 17 (3), 391-9
 - Leroux BG, Leisenring WM, Moolgavkar SH, Faustman EM (Aug 1996) A biologically-based dose-response model for developmental toxicology., Risk Analysis : an Official Publication of the Society for Risk Analysis, 16 (4), 449-58
 - Luebeck EG, Moolgavkar SH (Aug 1996) Biologically based cancer modeling., Drug and Chemical Toxicology, 19 (3), 221-43
 - Dewanji A, Luebeck EG, Moolgavkar SH (Jul 1996) A biologically based model for the analysis of premalignant foci of
arbitrary shape., Mathematical Biosciences, 135 (1), 55-68
 - Moolgavkar SH, Luebeck EG (Jul 1996) A critical review of the evidence on particulate air pollution and
mortality., Epidemiology (cambridge, Mass.), 7 (4), 420-8
 - Moolgavkar SH, Luebeck EG, Buchmann A, Bock KW (May 1996) Quantitative analysis of enzyme-altered liver foci in rats initiated with
diethylnitrosamine and promoted with 2,3,7,8-tetrachlorodibenzo-p-dioxin
or 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin., Toxicology and Applied Pharmacology, 138 (1), 31-42
 - Moolgavkar SH, Luebeck EG, Hall TA, Anderson EL, Particulate air pollution and mortality, Epidemiology (cambridge, Mass.), 7(2), 212-14, Mar 1996
- Luebeck EG, Curtis SB, Cross FT, Moolgavkar SH (Feb 1996) Two-stage model of radon-induced malignant lung tumors in rats: effects of
cell killing., Radiation Research, 145 (2), 163-73
 - Schwarz M, Buchmann A, Stinchcombe S, Luebeck G, Moolgavkar S, Bock KW (Dec 1995) Role of receptors in human and rodent hepatocarcinogenesis., Mutation Research, 333 (1-2), 69-79
 - Moolgavkar SH, Luebeck EG, Hall TA, Anderson EL (Sep 1995) Air pollution and daily mortality in Philadelphia., Epidemiology (cambridge, Mass.), 6 (5), 476-84
 - Moolgavkar SH, Luebeck EG (Sep 1995) Incorporating cell proliferation kinetics into models for cancer risk
assessment., Toxicology, 102 (1-2), 141-7
 - Stayner L, Smith R, Bailer AJ, Luebeck EG, Moolgavkar SH (Feb 1995) Modeling epidemiologic studies of occupational cohorts for the
quantitative assessment of carcinogenic hazards., American Journal of Industrial Medicine, 27 (2), 155-70
 - Luebeck EG, Grasl-Kraupp B, Timmermann-Trosiener I, Bursch W, Schulte-Hermann R, Moolgavkar SH (Feb 1995) Growth kinetics of enzyme-altered liver foci in rats treated with
phenobarbital or alpha-hexachlorocyclohexane., Toxicology and Applied Pharmacology, 130 (2), 304-15
 - Moolgavkar SH, Biological models of carcinogenesis and quantitative cancer risk
assessment, Risk Analysis : an Official Publication of the Society for Risk Analysis, 14(6), 879-82, Dec 1994
- Luebeck EG, Moolgavkar SH (Oct 1994) Simulating the process of malignant transformation., Mathematical Biosciences, 123 (2), 127-46
 - Moolgavkar SH, Air pollution and mortality, The New England Journal of Medicine, 330(17), 1237-8, Apr 1994
- Moolgavkar SH (Dec 1993) Cell proliferation and carcinogenesis models: general principles with
illustrations from the rodent liver system., Environmental Health Perspectives, 101 Suppl 5, 91-4
 - Zheng CJ, Byers B, Moolgavkar SH (Nov 1993) Allelic instability in mitosis: a unified model for dominant disorders., Proceedings of the National Academy of Sciences of the United States of America., 90 (21), 10178-82
 - Moolgavkar SH, Luebeck EG, Krewski D, Zielinski JM (May 1993) Radon, cigarette smoke, and lung cancer: a re-analysis of the Colorado
Plateau uranium miners' data., Epidemiology (cambridge, Mass.), 4 (3), 204-17
 - Moolgavkar SH, Luebeck EG (Dec 1992) Risk assessment of non-genotoxic carcinogens., Toxicology Letters, 64-65 Spec No, 631-6
 - Moolgavkar SH, Luebeck EG (Jun 1992) Interpretation of labeling indices in the presence of cell death., Carcinogenesis, 13 (6), 1007-10
 - Moolgavkar SH, Luebeck EG (Apr 1992) Multistage carcinogenesis: population-based model for colon cancer., Journal of the National Cancer Institute, 84 (8), 610-8
 - Luebeck EG, Moolgavkar SH, Buchmann A, Schwarz M (Dec 1991) Effects of polychlorinated biphenyls in rat liver: quantitative analysis
of enzyme-altered foci., Toxicology and Applied Pharmacology, 111 (3), 469-84
 - Dewanji A, Moolgavkar SH, Luebeck EG (Apr 1991) Two-mutation model for carcinogenesis: joint analysis of premalignant and
malignant lesions., Mathematical Biosciences, 104 (1), 97-109
 - Luebeck EG, Moolgavkar SH (Mar 1991) Stochastic analysis of intermediate lesions in carcinogenesis experiments., Risk Analysis : an Official Publication of the Society for Risk Analysis, 11 (1), 149-57
 - Luebeck EG, Moolgavkar SH (1991) Stochastic description of initiation and promotion in experimental
carcinogenesis., Annali Dell'istituto Superiore Di Sanita, 27 (4), 575-80
 - Moolgavkar SH, Luebeck EG (1991) The role of somatic mutations and cell replication kinetics in
quantitative cancer risk assessment., Progress in Clinical and Biological Research, 369, 469-79
 - Moolgavkar SH (1991) Carcinogenesis models: an overview., Basic Life Sciences, 58, 387-96; discussion 3
 - Moolgavkar SH (1991) A population perspective on multistage carcinogenesis., Princess Takamatsu Symposia, 22, 381-91
 - Moolgavkar SH, Cancer models, Epidemiology (cambridge, Mass.), 1(6), 419-20, Nov 1990
- Moolgavkar SH, Luebeck EG, de Gunst M, Port RE, Schwarz M (Aug 1990) Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis
experiments--I. Single agent regimen., Carcinogenesis, 11 (8), 1271-8
 - Moolgavkar SH, Luebeck G (Jun 1990) Two-event model for carcinogenesis: biological, mathematical, and
statistical considerations., Risk Analysis : an Official Publication of the Society for Risk Analysis, 10 (2), 323-41
 - Moolgavkar SH, Cross FT, Luebeck G, Dagle GE (Jan 1990) A two-mutation model for radon-induced lung tumors in rats., Radiation Research, 121 (1), 28-37
 - Moolgavkar SH (Dec 1989) A two-stage carcinogenesis model for risk assessment., Cell Biology and Toxicology, 5 (4), 445-60
 - Hahn RA, Moolgavkar SH (Nov 1989) Nulliparity, decade of first birth, and breast cancer in Connecticut
cohorts, 1855 to 1945: an ecological study., American Journal of Public Health, 79 (11), 1503-7
 - Dewanji A, Venzon DJ, Moolgavkar SH (Jun 1989) A stochastic two-stage model for cancer risk assessment. II. The number
and size of premalignant clones., Risk Analysis : an Official Publication of the Society for Risk Analysis, 9 (2), 179-87
 - Moolgavkar SH, Dewanji A, Luebeck G (Mar 1989) Cigarette smoking and lung cancer: reanalysis of the British doctors'
data., Journal of the National Cancer Institute, 81 (6), 415-20
 - Moolgavkar S, Dewanji A, Re: "Combined effect of childbearing, menstrual events, and body size on
age-specific breast cancer risk", American Journal of Epidemiology, 128(5), 1177-9, Nov 1988
- Moolgavkar SH (Oct 1988) Biologically motivated two-stage model for cancer risk assessment., Toxicology Letters, 43 (1-3), 139-50
 - Moolgavkar SH, Dewanji A, Venzon DJ (Sep 1988) A stochastic two-stage model for cancer risk assessment. I. The hazard
function and the probability of tumor., Risk Analysis : an Official Publication of the Society for Risk Analysis, 8 (3), 383-92
 - Moolgavkar S, Dewanji A (Mar 1988) Biologically based models for cancer risk assessment: a cautionary note., Risk Analysis : an Official Publication of the Society for Risk Analysis, 8 (1), 5-6
 - Moolgavkar SH, Venzon DJ (Nov 1987) General relative risk regression models for epidemiologic studies., American Journal of Epidemiology, 126 (5), 949-61
 - Lustbader ED, Moolgavkar SH (1987) Some problems of inference in cohort studies., Journal of Chronic Diseases, 40 Suppl 2, 133S-137S
 - Prentice RL, Moolgavkar SH, Farewell VT (1986) Biostatistical issues and concepts in epidemiologic research., Journal of Chronic Diseases, 39 (12), 1169-83
 - Moolgavkar SH (1986) Carcinogenesis modeling: from molecular biology to epidemiology., Annual Review of Public Health, 7, 151-69
 - Moolgavkar SH (1986) Hormones and multistage carcinogenesis., Cancer Surveys, 5 (3), 635-48
 - Moolgavkar SH, Lustbader ED, Venzon DJ (Oct-Dec 1985) Assessing the adequacy of the logistic regression model for matched
case-control studies., Statistics in Medicine, 4 (4), 425-35
 - Lustbader ED, Moolgavkar SH, Venzon DJ (Dec 1984) Tests of the null hypothesis in case-control studies., Biometrics, 40 (4), 1017-24
 - Moolgavkar SH, Stevens RG, Lee JA, Age and breast cancer incidence, European Journal of Cancer & Clinical Oncology, 20(11), 1453-4, Nov 1984
- Stevens RG, Moolgavkar SH (Jun 1984) Malignant melanoma: dependence of site-specific risk on age., American Journal of Epidemiology, 119 (6), 890-5
 - Stevens RG, Moolgavkar SH (Apr 1984) A cohort analysis of lung cancer and smoking in British males., American Journal of Epidemiology, 119 (4), 624-41
 - Venzon DJ, Moolgavkar SH (Jan 1984) Cohort analysis of malignant melanoma in five countries., American Journal of Epidemiology, 119 (1), 62-70
 - Moolgavkar SH (Apr 1983) Model for human carcinogenesis: action of environmental agents., Environmental Health Perspectives, 50, 285-91
 - Stevens RG, Moolgavkar SH, Lee JA (May 1982) Temporal trends in breast cancer., American Journal of Epidemiology, 115 (5), 759-77
 - Moolgavkar SH, Stevens RG (Jul 1981) Smoking and cancers of bladder and pancreas: risks and temporal trends., Journal of the National Cancer Institute, 67 (1), 15-23
 - Moolgavkar SH, Knudson AG Jr (Jun 1981) Mutation and cancer: a model for human carcinogenesis., Journal of the National Cancer Institute, 66 (6), 1037-52
 - Moolgavkar SH, Day NE, Stevens RG (Sep 1980) Two-stage model for carcinogenesis: Epidemiology of breast cancer in
females., Journal of the National Cancer Institute, 65 (3), 559-69
 - Moolgavkar S, Multistage models for carcinogenesis, Journal of the National Cancer Institute, 65(2), 215-6, Aug 1980
- Stevens RG, Lee JA, Moolgavkar SH, No association between oral contraceptives and malignant melanomas, The New England Journal of Medicine, 302(17), 966, Apr 1980
- Stevens RG, Moolgavkar SH (Dec 1979) Estimation of relative risk from vital data: smoking and cancers of the
lung and bladder., Journal of the National Cancer Institute, 63 (6), 1351-7
 - Moolgavkar SH, Stevens RG, Lee JA (Mar 1979) Effect of age on incidence of breast cancer in females., Journal of the National Cancer Institute, 62 (3), 493-501
 - Moolgavkar SH (Jul 1978) The multistage theory of carcinogenesis and the age distribution of cancer
in man., Journal of the National Cancer Institute, 61 (1), 49-52
 - Moolgavkar SH, Lee JA, Hade RD (Jun 1978) Comparison of age-specific mortality from breast cancer in males in the
United States and Japan., Journal of the National Cancer Institute, 60 (6), 1223-5

Profile DetailsIndividual Expertise profile of Suresh H. Moolgavkar, Copyright Suresh H. Moolgavkar. © COS Expertise TM, 2009, ProQuest LLC All rights reserved. |