Dr. Miriam Weber Nielsen

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Michigan State University
College of Agriculture & Natural Resources
Animal Science
Assistant ProfessorAppointed: 1999
Professional Headshot of Miriam Weber Nielsen

Mailing Address

Michigan State University
Department of Animal Science
1250E Anthony Hall
East Lansing, Michigan 48824-1225
United States

Contact Information

Phone: (517) 432-5443
Fax: (517) 353-1699
msw@msu.edu

Qualifications

Ph.D., Virginia Polytechnic Institute and State University, Lactation Physiology, 1998.
M.S., Virginia Polytechnic Institute and State University, Lactation Physiology, 1995.

Expertise and Research Interests

Elucidation of mechanisms underlying hormonal regulation of mammary development

Future Research

Research efforts are focused on characterizing hormonal and nutritional regulation of mammary growth and development.

Current work includes identifying the mechanisms mediating nutritional impairment of mammary development in prepubertal heifers, and evaluating the effects of accelerated growth of dairy heifers on body and mammary growth, reproduction and lactation.

Research utilizes a variety of techniques including cell culture and functional genomics approaches.

Keywords

COS Keywords:

Animal Science, Bioethics, Breast Milk, Dairy Science, Endocrinology, Ethics, Growth Factors, Hormones, Lactation, Reproductive Biology.

Additional Terms:

Bioethics, Dairy, Endocrinology, Ethics, Growth Factors, Heifers, Hormones, Lactation, Mammary, Management.

Memberships

American Dairy Science Association
American Registry of Professional Animal Scientists
Gamma Sigma Delta
Sigma Xi, The Scientific Research Society

Honors and Awards

Outstanding Teacher Award -- American Society of Animal Science & American Dairy Science Association -- Midwest sections, ADM Alliance Nutrition, Inc., Michigan State University

Previous Positions

1995-1996, Graduate Research Assistant, Danish Institute of Agricultural Sciences, Product Quality, Growth and Physiology
1993-1998, Graduate Research Assistant, Virginia Polytechnic Institute and State University, College of Agriculture and Life Sciences, Dairy Science, Lactation Physiology

Funding Received

  • United States Department of Agriculture (USDA): Interaction of IGF-I and leptin in bovine mammary development, $270,000, Sep 1, 2002 to Aug 31, 2005.
  • United States Department of Agriculture (USDA): Leptin Regulation of Bovine Mammary Cell Proliferation, $142,029, Sep 1, 2000 to Aug 31, 2002.
  • Animal Initiative Industry Coalition: Increasing milk production potential through intensified calf growth, $8,000, Oct 1, 2002 to Sep 30, 2003.
  • USDA IFAFS: Enhancing management and profitability on small and mid-sized dairy farms, $1,900,000, Oct 1, 2001 to Sep 30, 2005.
  • Michigan Corn Growers Association/Corn Marketing Program of Michigan: Grain Intake of Calves and Milk Production Potential, $43,740, Mar 2000 to Mar 2001.
  • MSU Animal Agriculture Initiative: Influence of confinement and exercise on bone development, $44,096, Jun 2000 to Jun 2001.
  • Animal Industry Coalition: Development of Gene Discovery cDNA Libraries and Microarray Sets for Swine and Cattle, $71,400, Jul 2001 to Jun 2002.
  • United States Department of Agriculture (USDA): A novel dairy management learning experience for undergraduates, $150,766, 2004 to 2007.
  • Animal Initiative Industry Coalition: Increasing milk production potential through intensified calf growth, $20,790, 2003 to 2004.

Publications

  • Brown EG, Vandehaar MJ, Daniels KM, Liesman JS, Chapin LT, Keisler DH, Nielsen MS, Effect of Increasing Energy and Protein Intake on Body Growth and Carcass Composition of Heifer Calves., Journal of Dairy Science, 88(2), 585-94, Feb 2005 Abstract
  • Brown EG, Vandehaar MJ, Daniels KM, Liesman JS, Chapin LT, Forrest JW, Akers RM, Pearson RE, Nielsen MS, Effect of Increasing Energy and Protein Intake on Mammary Development In Heifer Calves., Journal of Dairy Science, 88(2), 595-603, Feb 2005 Abstract
  • Suchyta, S.P., Sipkovsky, S., R.G. Halgren, R. Kruska, M. Elftman, M.S. Weber Nielsen, M.J. VandeHaar, L. Xiao, R.J. Tempelman, and P.M. Coussens, Bovine mammary gene expression profiling using a cDNA microarray enhanced for mammary specific transcripts, Physiol. Genomics, 16, 8-18, 2004
  • Weber Nielsen, M.S., J.J. Domecq, L.E. Davis, D.K. Beede, M. Budine and F. Martsolf, A partnership of universities and agri-business for an effective dairy herd management learning experience for undergraduates: The Dairy Challenge, Journal of Dairy Science, 86, 1029-1035, March 2003
  • Weber Nielsen, MS and E Bergfeld, Critical perspectives of animal agriculture: A response, Journal of Animal Science, 81, 2908-2911, 2003
  • Berry, S.D.K., M.S. Weber Nielsen, P.L. Boyle, K. Sejrsen, and R.M. Akers, Use of an immortalized bovine mammary epithelial cell line (MAC-T) to measure the mitogenic capacity of extracts of heifer mammary tissue: effects of nutrition and ovariectomy, Dom. Anim. Endocrinol, 25, 245-253, 2003
  • Silva LF, VandeHaar MJ, Weber Nielsen MS, Smith GW, Evidence for a local effect of leptin in bovine mammary gland, Journal of Dairy Science, 85(12), 3277-86, December 2002 Abstract
  • M.S. Weber, P.L. Boyle, B.A. Corl, E.A. Wong, F.C. Gwazdauskas, and R.M. Akers, Mammary synthesis of insulin-like growth factor-I in transgenic mice: Milk composition and growth of suckling pups, Transgenics, 3, 143-152, 2001
  • Weber MS, Purup S, Vestergaard M, Akers RM, Sejrsen K, Nutritional and somatotropin regulation of the mitogenic response of mammary cells to mammary tissue extracts, Domestic Animal Endocrinology, 18(1), 159-64, Jan 2000 Abstract
  • Weber MS, Purup S, Vestergaard M, Akers RM, Sejrsen K, Regulation of local synthesis of insulin-like growth factor-I and binding proteins in mammary tissue, Journal of Dairy Science, 83(1), 30-7, Jan 2000 Abstract
  • S Purup, M Vestergaard, MS Weber, K Plaut, RM Akers, K Sejrsen, Local regulation of pubertal mammary growth in heifers, Journal of Animal Science, 78(Supplement 3), 36-47, 2000
  • Sejrsen K, Purup S, Vestergaard M, Weber MS, Knight CH, Growth hormone and mammary development, Domestic Animal Endocrinology, 17(2-3), 117-29, October 1999 Abstract
  • Weber MS, Purup S, Vestergaard M, Ellis SE, Scnderg ard-Andersen J, Akers RM, Sejrsen K, Contribution of insulin-like growth factor (IGF)-I and IGF-binding protein-3 to mitogenic activity in bovine mammary extracts and serum, Journal of Endocrinology, 161(3), 365-73, June 1999 Abstract
  • Weber MS, Boyle PL, Corl BA, Wong EA, Gwazdauskas FC, Akers RM, Expression of ovine insulin-like growth factor-1 (IGF-1) stimulates alveolar bud development in mammary glands of transgenic mice, Endocrine, 8(3), 251-9, June 1998 Abstract

Profile Details

Last Updated: 1/29/2008

COS Expertise ID #466337
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