University of Washington School of Medicine Pathology | |
QualificationsFellowship, Yale University, Gastrointestinal/Hepatic Pathology, Department of Pathology, 2002. Residency, George Washington University, Anatomic and Clinical Pathology, 2001. Ph.D., University of Pennsylvania, Cell and Molecular Biology, 1997. M.D., National Taiwan University, 1989. Expertise and Research Interests- Research interest: Non-alcoholic fatty liver disease (NAFLD) Hepatitis C Hepatocarcinogenesis Pathology in liver transplantation Gastrointestinal, Hepatobiliary and pancreatic pathology
Current License to Practice: State of Washington, since 2002
- Board Certification: General Medical Board:Since January 2000 American Board of Pathology (Anatomic and Clinical Pathology), since 2002 Other ExpertisePathology Committee, NIH sponsored non-alcoholic steatohepatitis(NASH)-Clinical Research Network, 2002-present
Member of the GI Oncology Program, Fred Hutchinson Cancer Center/ University of Washington Cancer Consortium, 2004-present
Member of Working Party in Formulating the Guidelines for the Assessment and Management of NAFLD in the Asia-Pacific Region, 2006-present KeywordsCOS Keywords:Cancer Or Carcinogenesis, Gastroenterology, Hepatitis, Hepatology, Internal Medicine, Pathology.Additional Terms:Gastroenterology, Hepatology.Languages(Reading, Writing, Speaking)Chinese, Classical: (Fluent, Fluent, Fluent) Chinese, Mandarin: (Fluent, Fluent, Fluent) Chinese, Min Nan: (Fluent, Fluent, Fluent) Japanese: (Functional, Basic, Basic) MembershipsAmerican Association for the Study of Liver Disease American Society of Clinical Pathologists College of American Pathologists Hans Popper Hepatopathology Society Rodger Haggit Gastrointestinal Pathology Society United States and Canadian Academy of Pathology Publications- Farrell GC, Larter CZ, Hou JY, Zhang RH, Yeh MM, Williams J, Dela Pena A, Francisco R, Osvath SR, Brooling J, Teoh N, Sedger LM (Mar 2009) Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression., Journal of Gastroenterology and Hepatology, 24 (3), 443-52
 - Joyce MA, Walters KA, Lamb SE, Yeh MM, Zhu LF, Kneteman N, Doyle JS, Katze MG, Tyrrell DL (Feb 2009) HCV induces oxidative and ER stress, and sensitizes infected cells to apoptosis in SCID/Alb-uPA mice., PLoS Pathogens, 5 (2), e1000291
 - Kuo FY, Swanson PE, Yeh MM (Jan 2009) Pancreatic acinar tissue in liver explants: a morphologic and immunohistochemical study., The American Journal of Surgical Pathology, 33 (1), 66-71
 - Ahmad I, Iyer A, Marginean CE, Yeh MM, Ferrell L, Qin L, Bifulco CB, Jain D (Jan 2009) Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma., Human Pathology
 - Yeh MM (2009) Pathologic Diagnosis of Biliary Atresia on Liver Biopsy: Is Tissue the Issue?, J Gastroenterology and Hepatology, In Press
- Fenton H, Torbenson M, Vivekanandan P, Yeh MM, Hart J, Ferrell L (2009) Marked iron accumulation in liver explants in the absence of major gene defects of hereditary hemochromatosis: a risk factor for cardiac failure, Transplantation, In Press
- Pritchard CC, Yeh MM (2009) Pathology and Diagnostic Pitfalls of Cholangiocarcinoma: Rising Incidence of an Old Cancer, Pathology Case Reviews (14), 28-33
- Larter CZ, Yeh MM (Nov 2008) Animal models of NASH: getting both pathology and metabolic context right., Journal of Gastroenterology and Hepatology, 23 (11), 1635-48
 - Jewell KD, Toweill DL, Swanson PE, Upton MP, Yeh MM (Sep 2008) Gastric hyperplastic polyps in post transplant patients: a clinicopathologic study., Modern Pathology, 21 (9), 1108-12
 - Larter CZ, Yeh MM, Williams J, Bell-Anderson KS, Farrell GC (Sep 2008) MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes., Journal of Hepatology, 49 (3), 407-16
 - Chan EY, Larson AM, Fix OK, Yeh MM, Levy AE, Bakthavatsalam R, Halldorson JB, Reyes JD, Perkins JD (Jul 2008) Identifying risk for recurrent hepatocellular carcinoma after liver transplantation: implications for surveillance studies and new adjuvant therapies., Liver Transplantation, 14 (7), 956-65
 - Larter CZ, Yeh MM, Haigh WG, Williams J, Brown S, Bell-Anderson KS, Lee SP, Farrell GC (Apr 2008) Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways., Journal of Hepatology, 48 (4), 638-47
 - Lam MM, Swanson PE, Upton MP, Yeh MM (Feb 2008) Ovarian-type stroma in hepatobiliary cystadenomas and pancreatic mucinous cystic neoplasms: an immunohistochemical study., American Journal of Clinical Pathology, 129 (2), 211-8
 - Alexander J, Lord JD, Yeh MM, Cuevas C, Bakthavatsalam R, Kowdley KV (Feb 2008) Risk factors for recurrence of primary sclerosing cholangitis after liver transplantation., Liver Transplantation, 14 (2), 245-51
 - Yeh MM, Brunt EM (2008) Pathology of Fatty Liver: Differential Diagnosis of Non-Alcoholic Fatty Liver Disease, Diagnostic Histopathology (14), 586-97
- Campbell JS, Johnson MJ, Bauer RL, Hudkins KL, Gilbertson DG, Riehle KJ, Yeh MM, Alpers CE, Fausto N (2007) STI-571 reduces endothelial-like cell proliferation in the platelet-derived growth factor C induced-HCC model, Differentiation, 75 (9), 843-852
- Larter CZ, Yeh MM, Cheng J, Williams J, Brown S, dela Pena A, Bell-Anderson KS, Ferrall GC (2008) Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation, Journal of Gastroenterology and Hepatology, 23 (2), 267-75
- Yeh MM, Brunt EM (2007) Pathology of non-alcoholic fatty liver disease, American Journal of Clinical Pathology, 128 (5), 837-47
- Farrell GC, Larter CZ, Yeh MM, Chitturi S (2007) Obesity-related Fatty Liver Disease: Where are we now and what are the implications for the future, International journal of obesity, In Press
- Grimm E, Rulyak SJ, Sekijima J, Yeh MM (2007) Canalicular Adenoma Arising in the Esophagus, Archive of Pathology and Laboratory Medicine, 131 (10), 1595-7
- Diamond DL, Jacobs JM, Paeper B, Proll SC, Gritsenko MA, Carithers Jr. RL, Larson AM, Yeh MM, Camp II DG, Smith RD, Katze MG (2007) Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction, Hepatology, 46 (3), 649-57
- Yeh MM, Larson AM, Campbell JS, Fausto N, Rulyak SJ, Swanson PE (2007) The Expression of transformig growth factor-alpha in cirrhosis, dystplstic nodules, and hepatocellular carcinoma: immunohistochemical study of 70 cases, American Journal of Surgical Pathology, 31, 681-9
- Torbenson M, Yeh MM, Abraham SC (2007) Bile duct dysplasia in the setting of chronic hepatitis C and alcohol cirrhosis, American Journal of Surgical Pathology, 31 (9), 1410-1413
- Kowalewska J, Muhlfeld AS, Hudkins KL, Yeh MM, Farr AG, Ravetch JV, Alpers CE (2007) Thymic stromal lymphopoietin transgenic mice develop cryoglobulinemia and hepatits similar to human hepatitis C disease, American Journal of Pathology, 170, 981-9
- Balachandra B, Swanson PE, Upton MP, Yeh MM (2007) Adenocarcinoma arising in a gastrocystoplasty, Journal of Clinical Pathology, 60, 85-87
- Walters KA, Smith MW, Pal S, Thompson JC, Yeh MM, Thomas DL, Fitzgibbon M, Proll S, Fausto N, Gretch DR, Carithers RL jr., Shuhart MC, Katze MG (2006) Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals, Virology, 350 (2), 453-464
- Walters KA, Joyce MA, Thomson JC, Smith MW, Yeh MM, Prol S, Zhu LF, Gao TJ, Keneman N, Tyrell D, Katze MG (2006) Host-specified response to HCV infection in the chimeric SCID-beige/Alb-uPA mouse model: Role of the innate antiviral immune response, PLoS Pathogens, 2 (6), e59, 1-12
- Arsov T, Larter CZ, Nolan CJ, Petrovsky N, Goodnow CC, Teoh NC, Yeh MM, Farell GC (2006) Adaptive failure to high fat diet characterizes steatohepatitis in Alms1 mutant mice, Biochemical and Biophysical Research Communications, 342 (4), 1152-9
- Yeh MM, Larson AM, Tung BY, Swanson PE, Upton MP (2006) Endotheliitis in chronic viral hepatitis: A comparison between acute cellular rejection in liver allograft and non-alcoholic steatohepatitis, American Journal of Surgical Pathology, 30 (6), 727-33
- Torbenson MS, Chen YY, Brunt E, Jakate S, Liu YC, Yeh MM, Cummings OW, Ferrell L (2006) Glycongenic hepatopathy: An under-recognized hepatic complication of diabetes mellitus, American Journal of Surgical Pathology, 30 (4), 508-13
- Smith MW, Walters KA, Korth MJ, Fitzgibbon M, Proll S, Thompson JC, Yeh MM, Shuhart MC, Furlong JC, Cox PP, Thomas DL, Phillips JD, Kushner JP, Fausto N, Carither RL, Katze MG (2006) Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients, Gastroenterology, 130 (1), 179-87
- Yeh MM, Immunohistochemical analysis in hepatocellular carcinoma: does age matter?, American Journal of Clinical Pathology, 124(4), 491-3, Oct 2005
 - Yeh MM, Buskell ZJ, Seeff LB, Strader D, Wright EC, Goodman ZD (Sep 2005) More severe parenchymal injury in chronic hepatitis C acquired by recent injection drug use, Journal of Clinical Gastroenterology, 39 (8), 722-7
- Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, Yeh MM, McCullough AJ, Sanyal AJ, Nonalcoholic Steatohepatitis Clinical Research Network (Jun 2005) Design and validation of a histological scoring system for nonalcoholic fatty liver disease, Hepatology, 41 (6), 1313-21
- Campbell JS, Hughes SD, Gilbertson DG, Palmer TE, Holdren MS, Haran AC, Odell MM, Bauer RL, Ren HP, Haugen HS, Yeh MM, Fausto N (Mar 2005) Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma, Proceedings of the National Academy of Sciences of the United States of America, 102 (9), 3389-94
- Johnson EW, Holck PS, Levy AE, Yeh MM, Yeung RS (Aug 2004) The role of tumor ablation in bridging patients to liver transplantation, Archives of Surgery, 139 (8), 825-9; discussion 82
- Yeh MM, Tang LH, Wang S, Robert ME, Zheng W, Jain D (Jun 2004) Inhibin expression in ovarian-type stroma in mucinous cystic neoplasms of the pancreas, Applied Immunohistochemistry & Molecular Morphology, 12 (2), 148-52
- Hong-Curtis J, Yeh MM, Jain D, Lee JH (Nov-Dec 2004) Rapid progression of autoimmune hepatitis in the background of primary sclerosing cholangitis, Journal of Clinical Gastroenterology, 38 (10), 906-9
- Dighe MK, Parnell S, Yeh MM, Lalani T (2004) Hepatic epitheloid hemangioendothelioma: Multiphase CT appearance and correlation with pathology, Critical Reviews in Computed Tomography, 45 (5-6), 343-54
- Yeh MM (2004) Biopsy Interpretation of the Liver, Am J Clin Pathol, 122 (3), 473
Profile DetailsCOS Expertise ID #1168619 Individual Expertise profile of Matthew M. Yeh, Copyright Matthew M. Yeh. © COS Expertise TM, 2010, ProQuest LLC All rights reserved. |