Noah Gabriel Hoffman

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University of Washington
School of Medicine
Laboratory Medicine
Informatics
Professional Headshot of Noah Gabriel Hoffman

Mailing Address

University of Washington
Department of Laboratory Medicine
1959 NE Pacific Street, NW120
Box 357110
Seattle, Washington 98195-7110
United States

Contact Information

Phone: (206) 598-6131
ngh2@u.washington.edu
http://faculty.washington.edu/ngh2

Qualifications

Board Certification, American Board of Pathology, Clinical Pathology, 2008.
Residency, University of Washington, Clinical Pathology, 2008.
M.D., University of North Carolina, Chapel Hill, Medicine, 2005.
Ph.D., University of North Carolina, Chapel Hill, Microbiology and Immunology, 2005.
B.S., University of North Carolina, Chapel Hill, Biology, 1995.

Expertise and Research Interests

My clinical interests and responsibilities include the development and application of software and processes for the collection, management, and display of data generated in the clinical laboratory. In my research I am interested in creating applications and algorithms to classify medically important microorganisms using biological sequence information. My goal is to provide tools that will be useful in both clinical and basic science settings.

Keywords

COS Keywords:

DNA Sequencing, Medical Informatics.

Additional Terms:

Cataloging and Classification, DNA Sequencing, Data Management Or Analysis (Medical), Medical Informatics, Molecular Microbiology.

Memberships

Academy of Clinical Laboratory Physicians and Scientists
College of American Pathologists

Honors and Awards

2007-2008, Co-chief Resident, Department of Laboratory Medicine, University of Washington
2006, Strandjord-Clayson Award, Department of Laboratory Medicine, University of Washington, Software for sequenece-based identification of microorganisms
2006, Paul E. Strandjord Young Investigator Award, Academy of Clinical Physicians and Scientists
2005, Alpha Omega Alpha Medical Honor Society, UNC Chapel Hill School of Medicine, University of North Carolina, Chapel Hill
2004, UNC MD-PhD Program Alexander Scholar, UNC Chapel Hill School of Medicine, MD-PhD Program, UNC Chapel Hill School of Medicine
1994-1995, Barry M. Goldwater Scholarship, Barry M. Goldwater Scholarship Program
1994, Phi Beta Kappa, UNC Chapel Hill College of Arts and Sciences

Previous Positions

1998-2003, Graduate Student, UNC Chapel Hill, Microbiology and Immunology, Laboratory of Ronald Swanstrom

Patents

Polypeptides having a functional domain of interest and methods of identifying and using same, Patent Number: 7223547, 2007, Institution, United States of America.
Polypeptides having a functional domain of interest and methods of identifying and using same, Patent Number: 6709821, 2004, Institution, United States of America.
Polypeptides having a functional domain of interest and methods of identifying and using same, Patent Number: 6309820, 2001, Institution, United States of America.

Publications

  • Knies JL, Dang KK, Vision TJ, Hoffman NG, Swanstrom R, Burch CL (Aug 2008) Compensatory evolution in RNA secondary structures increases substitution rate variation among sites., Molecular biology and evolution, 25 (8), 1778-87 Abstract
  • Hoffman NG, Cook L, Atienza EE, Limaye AP, Jerome KR (Aug 2008) Marked variability of BK virus load measurement using quantitative real-time PCR among commonly used assays., Journal of clinical microbiology, 46 (8), 2671-80 Abstract
  • Patel MB, Hoffman NG, Swanstrom R (Jan 2008) Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins., Journal of virology, 82 (2), 903-16 Abstract
  • Hoffman NG, Cookson BT (Jun 2007) Letter to editor in reply to Case 8-2007: a man with chest pain followed by cardiac arrest., The New England journal of medicine, 356 (25), 2652-3; author reply Abstract
  • Henderson GJ, Hoffman NG, Ping LH, Fiscus SA, Hoffman IF, Kitrinos KM, Banda T, Martinson FE, Kazembe PN, Chilongozi DA, Cohen MS, Swanstrom R (Dec 2004) HIV-1 populations in blood and breast milk are similar., Virology, 330 (1), 295-303 Abstract
  • Ritola K, Pilcher CD, Fiscus SA, Hoffman NG, Nelson JA, Kitrinos KM, Hicks CB, Eron JJ, Swanstrom R (Oct 2004) Multiple V1/V2 env variants are frequently present during primary infection with human immunodeficiency virus type 1., Journal of virology, 78 (20), 11208-18 Abstract
  • Brumme ZL, Dong WW, Yip B, Wynhoven B, Hoffman NG, Swanstrom R, Jensen MA, Mullins JI, Hogg RS, Montaner JS, Harrigan PR (Mar 2004) Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy., AIDS (London, England), 18 (4), F1-9 Abstract
  • Hoffman NG, Schiffer CA, Swanstrom R (Sep 2003) Covariation of amino acid positions in HIV-1 protease., Virology, 314 (2), 536-48 Abstract
  • Kitrinos KM, Hoffman NG, Nelson JA, Swanstrom R (Jun 2003) Turnover of env variable region 1 and 2 genotypes in subjects with late-stage human immunodeficiency virus type 1 infection., Journal of virology, 77 (12), 6811-22 Abstract
  • Hoffman NG, Seillier-Moiseiwitsch F, Ahn J, Walker JM, Swanstrom R (Apr 2002) Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop., Journal of virology, 76 (8), 3852-64 Abstract
  • Resch W, Hoffman N, Swanstrom R (Sep 2001) Improved success of phenotype prediction of the human immunodeficiency virus type 1 from envelope variable loop 3 sequence using neural networks., Virology, 288 (1), 51-62 Abstract
  • McGrath KM, Hoffman NG, Resch W, Nelson JA, Swanstrom R (Aug 2001) Using HIV-1 sequence variability to explore virus biology., Virus research, 76 (2), 137-60 Abstract
  • Yamabhai M, Hoffman NG, Hardison NL, McPherson PS, Castagnoli L, Cesareni G, Kay BK (Nov 1998) Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains., The Journal of biological chemistry, 273 (47), 31401-7 Abstract
  • Kurakin A, Hoffman NG, Kay BK (Nov 1998) Molecular recognition properties of the C-terminal Sh3 domain of the Cbl associated protein, Cap., The journal of peptide research : official journal of the American Peptide Society, 52 (5), 331-7 Abstract
  • Ribon V, Printen JA, Hoffman NG, Kay BK, Saltiel AR (Feb 1998) A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes., Molecular and cellular biology, 18 (2), 872-9 Abstract
  • Ward JG, Blomberg P, Hoffman N, Yao MC (Sep 1997) The intranuclear organization of normal, hemizygous and excision-deficient rRNA genes during developmental amplification in Tetrahymena thermophila., Chromosoma, 106 (4), 233-42 Abstract
  • Hoffman NG, Sparks AB, Carter JM, Kay BK (Oct 1996) Binding properties of SH3 peptide ligands identified from phage-displayed random peptide libraries., Molecular diversity, 2 (1-2), 5-12 Abstract
  • Sparks AB, Hoffman NG, McConnell SJ, Fowlkes DM, Kay BK (Jun 1996) Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins., Nature biotechnology, 14 (6), 741-4 Abstract
  • Sparks AB, Rider JE, Hoffman NG, Fowlkes DM, Quillam LA, Kay BK (Feb 1996) Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2., Proceedings of the National Academy of Sciences of the United States of America, 93 (4), 1540-4 Abstract

Profile Details

Last Updated: 12/2/2008

COS Expertise ID #1322545
Reference this profile directly: http://myprofile.cos.com/ngh2