Prof. Edward Odell

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King's College London
Dental Institute
Oral Pathology
ProfessorAppointed: 1988
King's College London
Guy's and St Thomas' NHS Foundation Trust
Oral Pathology
Honorary ConsultantAppointed: 1988
Professional Headshot of Edward Odell

Mailing Address

Dept. of Oral Pathology GKT Dental Institute
Floor 28 Tower
Guy's Hospital
London, SE1 9RT
United Kingdom

Contact Information

Phone: +44 (0)207 188 4378
edward.odell@kcl.ac.uk

Qualifications

MILTHE, 2002.
FRCPath, Royal College of Pathologists, 2001.
MRCPath, Royal College of Pathologists, 1993.
Ph.D., University of London, 1988.
M.Sc., University of London, 1983.
F.D.S., Royal College of Surgeons of Edinburgh, 1982.
B.D.S., University of London, 1979.

Expertise and Research Interests

- Oral and pharyngeal carcinoma
- Oral premalignant lesions and oral premalignancy
- Head and neck histopathology
- Salivary gland cancer

Current interest in image-based ploidy analysis for predicting malignant transformation in oropharyngeal premalignancy and genome wide analysis of premalignancy.

Other Expertise

Member Institute of Learning and Teaching

Teaching interests in problem based learning and integrated subject teaching and assessment. Teacher on courses: Oral Disease, Human Disease, General Pathology, Molecular genetics.

General Dental Council visitor and new schools inspector.
External examiner Leeds, Dublin

Internal assessment organiser for Oral Disease Course year 4/5 BDS with particular interests in OSCE assessment methods and computer based assessment.

Author of undergraduate textbooks:

- Odell EW Ed (2004) Clinical Problem Solving in Dentistry 2nd Edn. Churchill Livingstone
- Cawson RA and Odell EW (2008) Essentials of Oral Medicine and Pathology 8th Edition Churchill Livingstone
- Odell EW Ed (2000) Clinical Problem Solving in Dentistry. Churchill Livingstone
- Cawson RA and Odell EW (1999) Colour guide to Oral Pathology 2nd edition, Churchill Livingstone
- Odell EW and Morgan PR (1998) Biopsy Pathology of the Oral Tissues. Chapman and Hall
- Williams D, Hughes F, Odell E and Farthing P. (1992, reprinted 1999) The Pathology of Periodontal Disease. Oxford University Press

Keywords

COS Keywords:

Dentistry, Oral Diseases.

Additional Terms:

Dysplasia, Molecular Oncology, Oral Cancer, Oral Premalignancy, Oral Squamous Carcinoma, Peroxidase, Salivary Neoplasms.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)

Memberships

American Academy of Oral and Maxillofacial Pathology
Association of Clinical Pathologists
British Dental Association
British Society for Oral and Maxillofacial Pathology
Institute for Learning and Teaching
International Association for Dental Research
Pathological Society of Great Britain and Ireland

Funding Received

  • Charitable Foundation of Guy's and St Thomas' Hospitals: Specific Chromosomal anomalies in oral premalignant lesions revealed by SNP array CGH, £37,920, 2006 to 2009.
  • KCL College Teaching Fund: Educational assessment of virtual microscopy in GKT schools, £49,495, 2006 to 2008.
  • KCL College Teaching Fund: Student management of on-line assessment modalities, £38,546, 2005 to 2007.
  • I Thompson, P Robinson, T Watson, R Cook and EW Odell. EPSRC.: Ceramic Lattice analysis, £465,000, 2003 to .
  • M Sperandio and E Odell, CAPES Brazil: Genome wide analysis of oropharyngeal malignancy, £95,958, 2003 to 2006.
  • Charitable Foundation of Guy's and St Thomas' Hospitals: E Odell: Ploidy analysis in oral dysplasia, £222,000, 2002 to 2005.
  • EPSRC MedLINK: DJ Hawkes, DLG Hill, M Gleeson, LD Griffin, M McGurk, AJ Strong, M. Fenlon, E. Odell: Microscope Asssisted Guided Interventions using intra-operative Imaging (MAGI II), £229,021, 2001 to 2004.
  • E W Odell, R W Evans and V A Gant: The Wellcome Trust Project Grant: Mechanism of killing of bacteria by short synthetic peptides, £164,344, 2000 to 2003.
  • E Odell: GKT PhD Studentship: Dysregulation of CD44 splicing in oral carcinoma, £35,000, 1999 to 2002.

Publications

  • Cawson RA (2008) Cawsons Essentials of Oral Pathology and Medicine, Elsevier
  • Ayoub A, Challa SR, Abu-Serriah M, McMahon J, Moos K, Creanor S, Odell E (Dec 2007) Use of a composite pedicled muscle flap and rhBMP-7 for mandibular reconstruction., International journal of oral and maxillofacial surgery, 36 (12), 1183-92 Abstract
  • Klanrit P, Flinterman MB, Odell EW, Melino G, Killick R, Norris JS, Tavassoli M (Nov 2007) Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptin., Cell cycle (Georgetown, Tex.), 7 (2) Abstract
  • Brown AL, Odell EW, Mantle PG (Oct 2007) DNA ploidy distribution in renal tumours induced in male rats by dietary ochratoxin A., Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 59 (2), 85-95 Abstract
  • Huang X, Pateromichelakis S, Hills A, Sherriff M, Lyons A, Langdon J, Odell E, Morgan P, Harrison J, Partridge M (Oct 2007) p53 mutations in deep tissues are more strongly associated with recurrence than mutation-positive mucosal margins., Clinical cancer research : an official journal of the American Association for Cancer Research, 13 (20), 6099-106 Abstract
  • Rautava J, Jee KJ, Miettinen PJ, Nagy B, Myllykangas S, Odell EW, Soukka T, Morgan PR, Heikinheimo K (Jun 2007) ERBB receptors in developing, dysplastic and malignant oral epithelia. Abstract
  • Köse O, Lalli A, Kutulola AO, Odell EW, Waseem A (Jun 2007) Changes in the expression of stem cell markers in oral lichen planus and hyperkeratotic lesions., Journal of oral science, 49 (2), 133-9 Abstract
  • Idowu BD, Al-Adnani M, O'Donnell P, Yu L, Odell E, Diss T, Gale RE, Flanagan AM (May 2007) A sensitive mutation-specific screening technique for GNAS1 mutations in cases of fibrous dysplasia: the first report of a codon 227 mutation in bone., Histopathology, 50 (6), 691-704 Abstract
  • Klanrit P, Sperandio M, Brown AL, Shirlaw PJ, Challacombe SJ, Morgan PR, Odell EW (Mar 2007) DNA ploidy in proliferative verrucous leukoplakia., Oral oncology, 43 (3), 310-6 Abstract
  • Vujovic S, Henderson S, Presneau N, Odell E, Jacques TS, Tirabosco R, Boshoff C, Flanagan AM (Jun 2006) Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas., The Journal of pathology, 209 (2), 157-65 Abstract
  • Scott IS, Odell E, Chatrath P, Morris LS, Davies RJ, Vowler SL, Laskey RA, Coleman N (Apr 2006) A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia., British journal of cancer, 94 (8), 1170-5 Abstract
  • Sanderson J, Nunes C, Escudier M, Barnard K, Shirlaw P, Odell E, Chinyama C, Challacombe S (Sep 2005) Oro-facial granulomatosis: Crohn's disease or a new inflammatory bowel disease?, 11 (9), 840-6 Abstract
  • Kalantzis A, Marshman Z, Falconer DT, Morgan PR, Odell EW (Jul 2005) Oral effects of low-dose methotrexate treatment., 100 (1), 52-62 Abstract
  • Abu-Serriah M, Kontaxis A, Ayoub A, Harrison J, Odell E, Barbenel J (May 2005) Mechanical evaluation of mandibular defects reconstructed using osteogenic protein-1 (rhOP-1) in a sheep model: a critical analysis., International Journal of Oral and Maxillofacial Surgery, 34 (3), 287-93 Abstract
  • Diwakar N, Sperandio M, Sherriff M, Brown A, Odell EW (Apr 2005) Heterogeneity, histological features and DNA ploidy in oral carcinoma by image-based analysis., Oral Oncology, 41 (4), 416-22 Abstract
  • Edwards PJ, Nijmeh AD, McGurk M, Odell E, Fenlon MR, Marsden PK, Hawkes DJ (2005) Validation of PET imaging by alignment to histology slices., Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 8 (Pt 2), 968-75 Abstract
  • Odell EW, Farthing PM, High A, Potts J, Soames J, Thakker N, Toner M, Williams HK, British Society for Oral and Maxillofacial Pathology, UK: minimum curriculum in oral pathology, European Journal of Dental Education : Official Journal of the Association for Dental Education in Europe., 8(4), 177-84, November 2004 Abstract
  • Abu-Serriah MM, Odell E, Lock C, Gillar A, Ayoub AF, Fleming RH, Histological assessment of bioengineered new bone in repairing osteoperiosteal mandibular defects in sheep using recombinant human bone morphogenetic protein-7, The British Journal of Oral & Maxillofacial Surgery, 42(5), 410-8, October 2004 Abstract
  • Farnaud S, Patel A, Odell EW, Evans RW, Variation in antimicrobial activity of lactoferricin-derived peptides explained by structure modelling, Fems Microbiology Letters, 238(1), 221-6, September 2004 Abstract
  • Abu-Serriah MM, Ayoub AF, Odell E, Carmichael S, Wray D, A minimally invasive novel design for a vascular-pedicled bone segment for experimental studies of reconstruction of mandibular defects, The British Journal of Oral & Maxillofacial Surgery, 42(3), 236-40, June 2004 Abstract
  • Chapple DS, Hussain R, Joannou CL, Hancock RE, Odell E, Evans RW, Siligardi G, Structure and association of human lactoferrin peptides with Escherichia coli lipopolysaccharide, Antimicrobial Agents and Chemotherapy, 48(6), 2190-8, June 2004 Abstract
  • Farnaud S, Spiller C, Moriarty LC, Patel A, Gant V, Odell EW, Evans RW, Interactions of lactoferricin-derived peptides with LPS and antimicrobial activity, Fems Microbiology Letters, 233(2), 193-9, April 2004 Abstract
  • Sheehy EC, Odell EW, Al-Jaddir G, Odontomas in the Primary Dentition: Literature Review and Case Report., Journal of Dentistry for Children (chicago, Ill.), 71(1), 73-6, Jan-Apr 2004 Abstract
  • Norton MR, Odell EW, Thompson ID, Cook RJ, Efficacy of bovine bone mineral for alveolar augmentation: a human histologic study, Clinical Oral Implants Research, 14(6), 775-83, December 2003 Abstract
  • Jayakrishnan A, Elmalah I, Hussain K, Odell EW, Basal cell adenocarcinoma in minor salivary glands, Histopathology, 42(6), 610-4, June 2003 Abstract
  • Bloor BK, Tidman N, Leigh IM, Odell E, Dogan B, Wollina U, Ghali L, Waseem A, Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization, American Journal of Pathology, 162(3), 963-75, March 2003 Abstract
  • Bloor BK, Rajarajan A, Jaafary-Haghighat K, Odell EW, Transcription and expression of CD44 variant exons by oro-pharyngeal squamous cell carcinomas, International Journal of Oncology, 21(4), 907-13, October 2002 Abstract
  • Odell EW, Morgan PR, Practitioner biopsy services, British Dental Journal, 193(4), 182, Aug 2002 Abstract
  • Patel V, Aldridge K, Ensley JF, Odell E, Boyd A, Jones J, Gutkind JS, Yeudall WA, Laminin-gamma2 overexpression in head-and-neck squamous cell carcinoma, International Journal of Cancer. Journal International Du Cancer, 99(4), 583-8, June 2002 Abstract
  • Renton T, Odell E, Drage NA, Differential diagnosis and treatment of autosomal dominant osteosclerosis of the mandible, The British Journal of Oral & Maxillofacial Surgery, 40(1), 55-9, February 2002 Abstract
  • Rezavandi K, Palmer RM, Odell EW, Scott DA, Wilson RF, Expression of ICAM-1 and E-selectin in gingival tissues of smokers and non-smokers with periodontitis, Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology., 31(1), 59-64, January 2002 Abstract
  • O'Regan EM, Gibb DH, Odell EW, Rapid growth of giant cell granuloma in pregnancy treated with calcitonin, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 92(5), 532-8, November 2001 Abstract
  • Eaton KA, Francis CA, Odell EW, Reynolds PA, Mason RD, Participating dentists' assessment of the pilot regional online videoconferencing in dentistry (PROVIDENT) project, British Dental Journal, 191(6), 330-5, September 2001 Abstract
  • Odell EW, Francis CA, Eaton KA, Reynolds PA, Mason RD, A study of videoconferencing for postgraduate continuing education in dentistry in the UK--the teachers' view, European Journal of Dental Education : Official Journal of the Association for Dental Education in Europe., 5(3), 113-9, August 2001 Abstract
  • Halfpenny W, Odell EW, Robinson PD, Cystic and glial mixed hamartoma of the tongue, Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology., 30(6), 368-71, July 2001 Abstract
  • Bloor BK, Jelvagharan M, White KN, Odell EW, Characterization of CD44 splicing patterns in normal keratinocytes, dysplastic and squamous carcinoma cell lines, International Journal of Oncology, 18(5), 1053-9, May 2001 Abstract
  • Economopoulou P, Hanby A, Odell EW, Expression of E-cadherin, cellular differentiation and polarity in epithelial salivary neoplasms, Oral Oncology, 36(6), 515-8, November 2000 Abstract
  • Scott DA, Stapleton JA, Palmer RM, Wilson RF, Sutherland G, Coward PY, Gustavsson G, Odell EW, Poston RN, Plasma concentrations of reputed tumor-associated soluble CD44 isoforms (v5 and v6) in smokers are dose related and decline on smoking cessation, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 9(11), 1211-4, November 2000 Abstract
  • Harrison M, Odell EW, Sheehy EC, Dental findings in Lowe syndrome, Pediatric Dentistry, 21(7), 425-8, 1999 Abstract
  • Palmer RM, Scott DA, Meekin TN, Poston RN, Odell EW, Wilson RF, Potential mechanisms of susceptibility to periodontitis in tobacco smokers, Journal of Periodontal Research, 34(7), 363-9, October 1999 Abstract
  • Bloor BK, Malik FK, Odell EW, Morgan PR, Quantitative assessment of apoptosis in oral lichen planus, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 88(2), 187-95, August 1999 Abstract
  • Chaudhry SI, Philpot NS, Odell EW, Challacombe SJ, Shirlaw PJ, Pyostomatitis vegetans associated with asymptomatic ulcerative colitis: a case report, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 87(3), 327-30, March 1999 Abstract
  • Goodisson DW, Burr RG, Creedon AJ, Stirling RW, Morgan PR, Odell EW, Buff RG, A case of metastasizing pleomorphic adenoma, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 87(3), 341-5, March 1999 Abstract
  • Harrison M, Odell EW, Agrawal M, Saravanamuttu R, Longhurst P, Gingival fibromatosis with prune-belly syndrome, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 86(3), 304-7, September 1998 Abstract
  • Oliveira DT, Sherriff M, Odell EW, Expression of CD44 variant exons by primary and metastatic oral squamous carcinomas, Journal of Oral Pathology and Medicine, 27(7), 303-7, August 1998 Abstract
  • Chapple DS, Mason DJ, Joannou CL, Odell EW, Gant V, Evans RW, Structure-function relationship of antibacterial synthetic peptides homologous to a helical surface region on human lactoferrin against Escherichia coli serotype O111, Infection and Immunity, 66(6), 2434-40, June 1998 Abstract
  • Odell EW, Lombardi T, Shirlaw PJ, White CA, Minor salivary gland hyalinisation and amyloidosis in low-grade lymphoma of MALT, Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology., 27(5), 229-32, May 1998 Abstract
  • Chapple DS, Joannou CL, Mason DJ, Shergill JK, Odell EW, Gant V, Evans RW, A helical region on human lactoferrin. Its role in antibacterial pathogenesis, Advances in Experimental Medicine and Biology, 443, 215-20, 1998 Abstract
  • Oliveira DT, Odell EW, Expression of CD44 variant exons by normal oral epithelia, Oral Oncology, 33(4), 260-2, July 1997 Abstract
  • Koundouros E, Odell E, Coward P, Wilson R, Palmer RM, Soluble adhesion molecules in serum of smokers and non-smokers, with and without periodontitis, Journal of Periodontal Research, 31(8), 596-9, November 1996 Abstract
  • Odell EW, Sarra R, Foxworthy M, Chapple DS, Evans RW, Antibacterial activity of peptides homologous to a loop region in human lactoferrin, Febs Letters, 382(1-2), 175-8, March 1996 Abstract
  • Odell EW, Jani P, Sherriff M, Ahluwalia SM, Hibbert J, Levison DA, Morgan PR, The prognostic value of individual histologic grading parameters in small lingual squamous cell carcinomas. The importance of the pattern of invasion, Cancer, 74(3), 789-94, 1994 Abstract
  • Odell EW, Wu PJ, Susceptibility of Porphyromonas gingivalis and P. asaccharolytica to the non-oxidative killing mechanisms of human neutrophils, Archives of Oral Biology, 37(8), 597-601, August 1992 Abstract
  • Odell EW, Segal AW, Killing of pathogens associated with chronic granulomatous disease by the non-oxidative microbicidal mechanisms of human neutrophils, Journal of Medical Microbiology, 34(3), 129-35, March 1991 Abstract
  • Odell EW, Segal AW, The bactericidal effects of the respiratory burst and the myeloperoxidase system isolated in neutrophil cytoplasts, Biochimica Et Biophysica Acta, 971(3), 266-74, October 1988 Abstract
  • Rajarajan A, Bloor BK, Desai H, Stokes A, Odell EW, Variant CD44 expression by human fibroblasts., Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 13 (3), 307-18 Abstract
  • Odell EW, Biopsy Pathology of the Oral Tissues
  • Odell EW, Clinical Problem Solving in dentistry

Profile Details

Last Updated: 5/19/2008

COS Expertise ID #523741
Reference this profile directly: http://myprofile.cos.com/odell2