Dr. Maynard Victor Olson

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University of Washington
School of Medicine
Medicine
Medical Genetics
ProfessorAppointed: 1992
University of Washington
Genome Sciences
ProfessorAppointed: 1997
University of Washington
College of Engineering
Computer Science and Engineering
Adjunct ProfessorAppointed: 1996
Professional Headshot of Maynard Victor Olson

Mailing Address

Genome Center - MS 352145
225 Fluke Hall on Mason Rd.
University of Washington
Seattle, Washington 98195
United States

Contact Information

Phone: (206) 685-7346
Fax: (206) 616-5242
mvo@u.washington.edu

Qualifications

Ph.D., Stanford University, Chemistry, 1970.
B.S., California Institute of Technology, Chemistry, 1965.

Expertise and Research Interests

Large-scale genome analysis
Molecular evolution
Human genetic variation
Bacterial pathogenesis

Keywords

COS Keywords:

Bacterial Infections, Bioengineering, Bioinstrumentation, Biotechnology, Chemical Sciences, Computer and Information Sciences, Computer Engineering, Computer Graphics, DNA, Genes, Genetic Diseases, Genetics, Genomics, Medical Genetics, Mutagenesis, Pathogenesis, RNA.

Additional Terms:

DNA/RNA/Mutagenesis, Genes, Genetics/Genetic Diseases, Mapping.

Memberships

American Academy of Arts and Sciences
American Association for the Advancement of Science
American Philosophical Society
Genetics Society of America
National Academy of Sciences

Previous Positions

1989-1992, Investigator, Washington University in St. Louis, Howard Hughes Medical Institute
1986-1992, Professor, Washington University in St. Louis, School of Medicine, Genetics
1976-1979, Research Associate, University of Washington, College of Arts and Sciences, Genetics
1969-1976, Assistant Professor, Dartmouth College, Arts & Sciences, Chemistry

Publications

  • Smith EE, Sims EH, Spencer DH, Kaul R, Olson MV, Evidence for Diversifying Selection At the Pyoverdine Locus of Pseudomonas Aeruginosa., Journal of Bacteriology, 187(6), 2138-47, Mar 2005 Abstract
  • Hendrickson EL, Kaul R, Zhou Y, Bovee D, Chapman P, Chung J, Conway de Macario E, Dodsworth JA, Gillett W, Graham DE, Hackett M, Haydock AK, Kang A, Land ML, Levy R, Lie TJ, Major TA, Moore BC, Porat I, Palmeiri A, Rouse G, Saenphimmachak C, Soll D, Van Dien S, Wang T, Whitman WB, Xia Q, Zhang Y, Larimer FW, Olson MV, Leigh JA, Complete Genome Sequence of the Genetically Tractable Hydrogenotrophic Methanogen Methanococcus Maripaludis., Journal of Bacteriology, 186(20), 6956-69, Oct 2004 Abstract
  • Olson MV, Varki A, Genomics. the Chimpanzee Genome--a Bittersweet Celebration., Science, 305(5681), 191-2, Jul 2004 Abstract
  • Olson MV, Kas A, Bubb K, Qui R, Smith EE, Raymond CK, Kaul R, Hypervariability, Suppressed Recombination and the Genetics Of Individuality., Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences., 359(1441), 129-40, Jan 2004 Abstract
  • Jacobs MA, Alwood A, Thaipisuttikul I, Spencer D, Haugen E, Ernst S, Will O, Kaul R, Raymond C, Levy R, Chun-Rong L, Guenthner D, Bovee D, Olson MV, Manoil C, Comprehensive Transposon Mutant Library of Pseudomonas Aeruginosa., Proceedings of the National Academy of Sciences of the United States of America., 100(24), 14339-44, Nov 2003 Abstract
  • Spencer DH, Kas A, Smith EE, Raymond CK, Sims EH, Hastings M, Burns JL, Kaul R, Olson MV, Whole-genome Sequence Variation Among Multiple Isolates of Pseudomonas Aeruginosa., Journal of Bacteriology, 185(4), 1316-25, Feb 2003 Abstract
  • Olson MV, The New Quantitative Biology., Cold Spring Harbor Symposia on Quantitative Biology, 68, 495-502, 2003 Abstract
  • Olson MV, Varki A, Sequencing the Chimpanzee Genome: Insights Into Human Evolution And Disease., Nature Reviews. Genetics, 4(1), 20-8, Jan 2003 Abstract
  • Williams BJ, Golomb M, Phillips T, Brownlee J, Olson MV, Smith AL, Bacteriophage HP2 of Haemophilus Influenzae., Journal of Bacteriology, 184(24), 6893-905, Dec 2002 Abstract
  • Raymond CK, Sims EH, Kas A, Spencer DH, Kutyavin TV, Ivey RG, Zhou Y, Kaul R, Clendenning JB, Olson MV, Genetic Variation At the O-antigen Biosynthetic Locus in Pseudomonas Aeruginosa., Journal of Bacteriology, 184(13), 3614-22, Jul 2002 Abstract
  • Olson MV, The Human Genome Project: a Player's Perspective., Journal of Molecular Biology, 319(4), 931-42, Jun 2002 Abstract
  • Raymond CK, Sims EH, Olson MV, Linker-mediated Recombinational Subcloning of Large DNA Fragments Using Yeast., Genome Research, 12(1), 190-7, Jan 2002 Abstract
  • Wood DW, Setubal JC, Kaul R, Monks DE, Kitajima JP, Okura VK, Zhou Y, Chen L, Wood GE, Almeida NF Jr, Woo L, Chen Y, Paulsen IT, Eisen JA, Karp PD, Bovee D Sr, Chapman P, Clendenning J, Deatherage G, Gillet W, Grant C, Kutyavin T, Levy R, Li MJ, McClelland E, Palmieri A, Raymond C, Rouse G, Saenphimmachak C, Wu Z, Romero P, Gordon D, Zhang S, Yoo H, Tao Y, Biddle P, Jung M, Krespan W, Perry M, Gordon-Kamm B, Liao L, Kim S, Hendrick C, Zhao ZY, Dolan M, Chumley F, Tingey SV, Tomb JF, Gordon MP, Olson MV, Nester EW, The Genome of the Natural Genetic Engineer Agrobacterium Tumefaciens C58., Science, 294(5550), 2317-23, Dec 2001 Abstract
  • Olson MV, The Maps. Clone By Clone By Clone., Nature, 409(6822), 816-8, Feb 2001 Abstract
  • Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV, Complete Genome Sequence of Pseudomonas Aeruginosa PA01, An Opportunistic Pathogen., Nature, 406(6799), 959-64, Aug 2000 Abstract
  • Thayer EC, Olson MV, Karp RM, Error checking and graphical representation of multiple-complete-digest \(MCD\) restriction-fragment maps., Genome Research, 9(1), 79-90, Jan 1999 Abstract
  • Olson MV, When less is more: gene loss as an engine of evolutionary change., American Journal of Human Genetics, 64(1), 18-23, Jan 1999 Abstract
  • Olson M, Green P, A "quality-first" credo for the Human Genome Project., Genome Research, 8(5), 414-5, May 1998 Abstract
  • Wong GK-S, Yu J, Thayer EC, Olson MV, Multiple-complete-digest (MCD) restriction-fragment mapping: Generating sequence-ready maps for large-scale DNA sequencing, Proceedings of the National Academy of Sciences (USA), 94, 5225-5230, 1997
  • Gillett W, Hanks L, Wong G KS, Yu J, Lim R, Olson M V, Assembly of high-resolution restriction maps based on multiple complete digests of a redundant set of overlapping clones, Genomics, 33(3), 389-408, 1 May 1996 Abstract
  • Olson M V, A time to sequence, Science, 270(5235), 394-6, 20 Oct 1995 Abstract
  • Gnirke A, Iadonato S P, Kwok P Y, Olson M V, Physical calibration of yeast artificial chromosome contig maps by RecA-assisted restriction endonuclease (RARE) cleavage, Genomics, 24(2), 199-210, 15 Nov 1994 Abstract
  • Olson M V, The human genome project, Proceedings of the National Academy of Sciences (USA), 90(10), 4338-44, 15 May 1993 Abstract
  • Riles L, Dutchik J E, Baktha A, McCauley B K, Thayer E C, Leckie M P, Braden V V, Depke J E, Olson M V, Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs, Genetics, 134(1), 81-150, May 1993 Abstract
  • Gnirke A, Huxley C, Peterson K, Olson M V, Microinjection of intact 200- to 500-kb fragments of YAC DNA into mammalian cells, Genomics, 15(3), 659-67, March 1993 Abstract
  • Olson M V, Green P, Criterion for the completeness of large-scale physical maps of DNA, Cold Spring Harbor Symposia On Quantitative Biology, 58, 349-55, 1993 Abstract
  • Kwok P Y, Gremaud M F, Nickerson D A, Hood L, Olson M V, Automatable screening of yeast artificial-chromosome libraries based on the oligonucleotide-ligation assay, Genomics, 13(4), 935-41, August 1992 Abstract
  • Burke D T, Carle G F, Olson M V, Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors, Biotechnology, 24, 172-8, 1992 Abstract
  • Green E D, Mohr R M, Idol J R, Jones M, Buckingham J M, Deaven L L, Moyzis R K, Olson M V, Systematic generation of sequence-tagged sites for physical mapping of human chromosomes: application to the mapping of human chromosome 7 using yeast artificial chromosomes, Genomics, 11(3), 548-64, November 1991 Abstract
  • Green E D, Riethman H C, Dutchik J E, Olson M V, Detection and characterization of chimeric yeast artificial-chromosome clones, Genomics, 11(3), 658-69, November 1991 Abstract
  • Gnirke A, Barnes T S, Patterson D, Schild D, Featherstone T, Olson M V, Cloning and in vivo expression of the human GART gene using yeast artificial chromosomes, Embo Journal, 10(7), 1629-34, July 1991 Abstract
  • Link A J, Olson M V, Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution, Genetics, 127(4), 681-98, April 1991 Abstract
  • Olson M V, A tale of two cities, Analytical Chemistry, 63(7), 416A-420A, 1 Apr 1991 Abstract
  • Huxley C, Hagino Y, Schlessinger D, Olson M V, The human HPRT gene on a yeast artificial chromosome is functional when transferred to mouse cells by cell fusion., Genomics, 9(4), 742-50, April 1991 Abstract
  • Burke D T, Olson M V, Preparation of clone libraries in yeast artificial-chromosome vectors, Methods In Enzymology, 194, 251-70, 1991 Abstract
  • Green E D, Olson M V, Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping, Science, 250(4977), 94-8, 5 Oct 1990 Abstract
  • Imai T, Olson M V, Second-generation approach to the construction of yeast artificial-chromosome libraries [published erratum appears in Genomics 1991 May;10(1):300], Genomics, 8(2), 297-303, October 1990 Abstract
  • Drury H A, Green P, McCauley B K, Olson M V, Politte D G, Thomas L J Jr, Spatial normalization of one-dimensional electrophoretic gel images., Genomics, 8(1), 119-26, September 1990 Abstract
  • Green E D, Olson M V, Systematic screening of yeast artificial-chromosome libraries by use of the polymerase chain reaction, Proceedings of the National Academy of Sciences (USA), 87(3), 1213-7, February 1990 Abstract
  • Brownstein B H, Silverman G A, Little R D, Burke D T, Korsmeyer S J, Schlessinger D, Olson M V, Isolation of single-copy human genes from a library of yeast artificial chromosome clones, Science, 244(4910), 1348-51, 16 Jun 1989 Abstract

Profile Details

Last Updated: 9/9/2005

COS Expertise ID #307784
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