National Human Genome Research Institute Cancer Genetics Branch Comparative Genetics Section Chief, Cancer Genetics BranchAppointed: 2004 Fred Hutchinson Cancer Research Center Human Biology Division MemberAppointed: 2000 Fred Hutchinson Cancer Research Center Clinical Research Division MemberAppointed: 2000 | |
QualificationsPh.D., Oregon Health Sciences University, Microbiology and Immunology, 1987. B.S., University of Washington, 1981. Expertise and Research InterestsDr. Ostrander's research interests are in the area of genetic mapping and genomics. We have two main areas of study. First, we are mapping and identifying genetic variants that increase susceptibility to breast and prostate cancer in humans. Both family and population-based studies are underway. Second, we are interested in the development of the canine system for both understanding the role of genetic variation in complex traits.
Recently, we completed a genome wide scan of 255 prostate cancer families and identified several loci of interest. Stratification of our now complete dataset by clinical features of disease and family history suggest multiple loci of interest that are currently the focus of extensive follow-up and fine mapping studies. In addition, we are currently testing approximately 1000 candidate single nucleotide polymorphisms (SNPs) for association with prostate cancer in a population-based, case control study. Analysis of these data will highlight variants for additional study.
With regard to breast cancer we have focused on understanding the role of the breast cancer susceptibility genes BRCA1 and BRCA2 in women drawn from the general population. Our most recent study has focused on a large data set of nearly 3000 women, 1/3 of whom are African American, to define profiles of women likely to be at increased risk for being a BRCA1 or BRCA2 carrier. We are also taking an evolutionary approach to understanding the role of missense changes in BRCA1/BRCA2, with a long term goal of identifying subtle variants of low genetic penetrance that are associated with increased disease risk. Finally we are working to analyze SNPs identified by Genome Wide Association Studies (GWAS) to determine which are the at risk polymorphisms.
Finally, we and our collaborators have developed resources that allows us to utilize the human, rodent and canine genome sequence for identifying variants important in disease susceptibility, behavior, and morphologic variation in the domestic dog. We are using those resources to identify loci for several types of cancer including that of the bladder, skin, as well as malignant histiocytosis. We are also interested in finding genes for Addison's disease.
Additional canine studies focus on finding genes important in growth regulation by working closely with dog owners, breeders and kennel clubs. We are interested in the organization of the canine phylogeny and the utility of linkage disequilibrium for mapping complex traits of interest. Towards that end we have identified both loci and sequence level variants that are under strong selection for regulating overall body size in the domestic dog such as IGF-1. We continue to work towards identification of genes controlling differential growth of the canine leg length and width, skull shape, and overall body plan as manifest between distinct breeds of dog. KeywordsCOS Keywords:Cancer Or Carcinogenesis, Genetics, Oncogenes, Zoology.Additional Terms:Cancer Susceptibility, Canine Cancer, Canine Genome, Comparative Mapping, Dog Genetics, Genome Wide Association Study, Skeletal Morphology.Languages(Reading, Writing, Speaking)English: (Fluent, Fluent, Fluent) MembershipsAmerican Association for Advancement of Science American Association for Cancer Research American Society of Human Genetics Women in Cancer Research Previous Positions1993-2004, Head, Cancer Genetics Program,
Fred Hutchinson Cancer Research Center,
Divisions of Human Biology and Clinical Research
Publications- Tischkowitz MD, Yilmaz A, Chen LQ, Karyadi DM, Novak D, Kirchhoff T, Hamel N, Tavtigian SV, Kolb S, Bismar TA, Aloyz R, Nelson PS, Hood L, Narod SA, White KA, Ostrander EA, Isaacs WB, Offit K, Cooney KA, Stanford JL, Foulkes WD (Oct 2008) Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer., Cancer letters, 270 (1), 173-180
 - Fitzgerald LM, Karlins E, Karyadi DM, Kwon EM, Koopmeiners JS, Stanford JL, Ostrander EA (Sep 2008) Association of FGFR4 genetic polymorphisms with prostate cancer risk and prognosis., Prostate cancer and prostatic diseases
 - Kote-Jarai Z, Easton DF, Stanford JL, Ostrander EA, Schleutker J, Ingles SA, Schaid D, Thibodeau S, Dörk T, Neal D, Cox A, Maier C, Vogel W, Guy M, Muir K, Lophatananon A, Kedda MA, Spurdle A, Steginga S, John EM, Giles G, Hopper J, Chappuis PO, Hutter P, Foulkes WD, Hamel N, Salinas CA, Koopmeiners JS, Karyadi DM, Johanneson B, Wahlfors T, Tammela TL, Stern MC, Corral R, McDonnell SK, Schürmann P, Meyer A, Kuefer R, Leongamornlert DA, Tymrakiewicz M, Liu JF, O'Mara T, Gardiner RA, Aitken J, Joshi AD, Severi G, English DR, Southey M, Edwards SM, Al Olama AA, Eeles RA (Aug 2008) Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (8), 2052-61
 - Ostrander EA, Udler MS (Aug 2008) The role of the BRCA2 gene in susceptibility to prostate cancer revisited., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (8), 1843-8
 - Agalliu I, Salinas CA, Hansten PD, Ostrander EA, Stanford JL (Aug 2008) Statin use and risk of prostate cancer: results from a population-based epidemiologic study., American journal of epidemiology, 168 (3), 250-60
 - Pierce BL, Plymate S, Ostrander EA, Stanford JL (Jul 2008) Diabetes mellitus and prostate cancer risk., The Prostate, 68 (10), 1126-32
 - Schaid DJ, McDonnell SK, Carlson EE, Thibodeau SN, Stanford JL, Ostrander EA (Jul 2008) Searching for epistasis and linkage heterogeneity by correlations of pedigree-specific linkage scores., Genetic epidemiology, 32 (5), 464-75
 - Holt SK, Karyadi DM, Kwon EM, Stanford JL, Nelson PS, Ostrander EA (Jun 2008) Association of megalin genetic polymorphisms with prostate cancer risk and prognosis., Clinical cancer research : an official journal of the American Association for Cancer Research, 14 (12), 3823-31
 - Jones P, Chase K, Martin A, Davern P, Ostrander EA, Lark KG (Jun 2008) Single-nucleotide-polymorphism-based association mapping of dog stereotypes., Genetics, 179 (2), 1033-44
 - Salinas CA, Kwon E, Carlson CS, Koopmeiners JS, Feng Z, Karyadi DM, Ostrander EA, Stanford JL (May 2008) Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (5), 1203-13
 - Agalliu I, Suuriniemi M, Prokunina-Olsson L, Johanneson B, Collins FS, Stanford JL, Ostrander EA (May 2008) Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study., The Prostate, 68 (7), 740-7
 - Johanneson B, McDonnell SK, Karyadi DM, Hebbring SJ, Wang L, Deutsch K, McIntosh L, Kwon EM, Suuriniemi M, Stanford JL, Schaid DJ, Ostrander EA, Thibodeau SN (Feb 2008) Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb., Human genetics, 123 (1), 65-75
 - Hitte C, Kirkness EF, Ostrander EA, Galibert F (2008) Survey sequencing and radiation hybrid mapping to construct comparative maps., Methods in molecular biology (Clifton, N.J.), 422, 65-77
 - Ostrander EA, Johannesson B (2008) Prostate cancer susceptibility loci: finding the genes., Advances in experimental medicine and biology, 617, 179-90
 - Fleischer S, Sharkey M, Mealey K, Ostrander EA, Martinez M (2008) Pharmacogenetic and metabolic differences between dog breeds: their impact on canine medicine and the use of the dog as a preclinical animal model., The AAPS journal, 10 (1), 110-9
 - Spady TC, Ostrander EA (Jan 2008) Canine behavioral genetics: pointing out the phenotypes and herding up the genes., American journal of human genetics, 82 (1), 10-8
 - Cadieu E, Ostrander EA (Nov 2007) Canine genetics offers new mechanisms for the study of human cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (11), 2181-3
 - Wayne RK, Ostrander EA (Nov 2007) Lessons learned from the dog genome., Trends in genetics : TIG, 23 (11), 557-67
 - Parker HG, Kukekova AV, Akey DT, Goldstein O, Kirkness EF, Baysac KC, Mosher DS, Aguirre GD, Acland GM, Ostrander EA (Nov 2007) Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds., Genome research, 17 (11), 1562-71
 - Holick CN, Stanford JL, Kwon EM, Ostrander EA, Nejentsev S, Peters U (Oct 2007) Comprehensive association analysis of the vitamin D pathway genes, VDR, CYP27B1, and CYP24A1, in prostate cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (10), 1990-9
 - Parmigiani G, Chen S, Iversen ES, Friebel TM, Finkelstein DM, Anton-Culver H, Ziogas A, Weber BL, Eisen A, Malone KE, Daling JR, Hsu L, Ostrander EA, Peterson LE, Schildkraut JM, Isaacs C, Corio C, Leondaridis L, Tomlinson G, Amos CI, Strong LC, Berry DA, Weitzel JN, Sand S, Dutson D, Kerber R, Peshkin BN, Euhus DM (Oct 2007) Validity of models for predicting BRCA1 and BRCA2 mutations., Annals of internal medicine, 147 (7), 441-50
 - Agalliu I, Karlins E, Kwon EM, Iwasaki LM, Diamond A, Ostrander EA, Stanford JL (Sep 2007) Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer., British journal of cancer, 97 (6), 826-31
 - Schaid DJ, Stanford JL, McDonnell SK, Suuriniemi M, McIntosh L, Karyadi DM, Carlson EE, Deutsch K, Janer M, Hood L, Ostrander EA (Jul 2007) Genome-wide linkage scan of prostate cancer Gleason score and confirmation of chromosome 19q., Human genetics, 121 (6), 729-35
 - Schaid DJ, McDonnell SK, Carlson EE, Thibodeau SN, Ostrander EA, Stanford JL (Jul 2007) Affected relative pairs and simultaneous search for two-locus linkage in the presence of epistasis., Genetic epidemiology, 31 (5), 431-49
 - Camp NJ, Cannon-Albright LA, Farnham JM, Baffoe-Bonnie AB, George A, Powell I, Bailey-Wilson JE, Carpten JD, Giles GG, Hopper JL, Severi G, English DR, Foulkes WD, Maehle L, Moller P, Eeles R, Easton D, Badzioch MD, Whittemore AS, Oakley-Girvan I, Hsieh CL, Dimitrov L, Xu J, Stanford JL, Johanneson B, Deutsch K, McIntosh L, Ostrander EA, Wiley KE, Isaacs SD, Walsh PC, Thibodeau SN, McDonnell SK, Hebbring S, Schaid DJ, Lange EM, Cooney KA, Tammela TL, Schleutker J, Paiss T, Maier C, Grönberg H, Wiklund F, Emanuelsson M, Isaacs WB (Jun 2007) Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics., Human molecular genetics, 16 (11), 1271-8
 - Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA (May 2007) A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs., PLoS genetics, 3 (5), e79
 - Johanneson B, Deutsch K, McIntosh L, Friedrichsen-Karyadi DM, Janer M, Kwon EM, Iwasaki L, Hood L, Ostrander EA, Stanford JL (May 2007) Suggestive genetic linkage to chromosome 11p11.2-q12.2 in hereditary prostate cancer families with primary kidney cancer., The Prostate, 67 (7), 732-42
 - Suuriniemi M, Agalliu I, Schaid DJ, Johanneson B, McDonnell SK, Iwasaki L, Stanford JL, Ostrander EA (Apr 2007) Confirmation of a positive association between prostate cancer risk and a locus at chromosome 8q24., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (4), 809-14
 - Sutter NB, Bustamante CD, Chase K, Gray MM, Zhao K, Zhu L, Padhukasahasram B, Karlins E, Davis S, Jones PG, Quignon P, Johnson GS, Parker HG, Fretwell N, Mosher DS, Lawler DF, Satyaraj E, Nordborg M, Lark KG, Wayne RK, Ostrander EA (Apr 2007) A single IGF1 allele is a major determinant of small size in dogs., Science (New York, N.Y.), 316 (5821), 112-5
 - Spady TC, Ostrander EA (Mar 2007) Canid genomics: mapping genes for behavior in the silver fox., Genome research, 17 (3), 259-63
 - Pierce BL, Friedrichsen-Karyadi DM, McIntosh L, Deutsch K, Hood L, Ostrander EA, Austin MA, Stanford JL (Mar 2007) Genomic scan of 12 hereditary prostate cancer families having an occurrence of pancreas cancer., The Prostate, 67 (4), 410-5
 - Agalliu I, Kwon EM, Zadory D, McIntosh L, Thompson J, Stanford JL, Ostrander EA (Feb 2007) Germline mutations in the BRCA2 gene and susceptibility to hereditary prostate cancer., Clinical cancer research : an official journal of the American Association for Cancer Research, 13 (3), 839-43
 - Abecasis G, Tam PK, Bustamante CD, Ostrander EA, Scherer SW, Chanock SJ, Kwok PY, Brookes AJ (Feb 2007) Human Genome Variation 2006: emerging views on structural variation and large-scale SNP analysis., Nature genetics, 39 (2), 153-5
 - Quignon P, Herbin L, Cadieu E, Kirkness EF, Hédan B, Mosher DS, Galibert F, André C, Ostrander EA, Hitte C (2007) Canine population structure: assessment and impact of intra-breed stratification on SNP-based association studies., PLoS ONE, 2 (12), e1324
 - Trabert B, Malone KE, Daling JR, Doody DR, Bernstein L, Ursin G, Marchbanks PA, Strom BL, Humphrey MC, Ostrander EA (2007) Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women., Breast cancer research : BCR, 9 (6), R84
 - Schaid DJ, McDonnell SK, Zarfas KE, Cunningham JM, Hebbring S, Thibodeau SN, Eeles RA, Easton DF, Foulkes WD, Simard J, Giles GG, Hopper JL, Mahle L, Moller P, Badzioch M, Bishop DT, Evans C, Edwards S, Meitz J, Bullock S, Hope Q, Guy M, Hsieh CL, Halpern J, Balise RR, Oakley-Girvan I, Whittemore AS, Xu J, Dimitrov L, Chang BL, Adams TS, Turner AR, Meyers DA, Friedrichsen DM, Deutsch K, Kolb S, Janer M, Hood L, Ostrander EA, Stanford JL, Ewing CM, Gielzak M, Isaacs SD, Walsh PC, Wiley KE, Isaacs WB, Lange EM, Ho LA, Beebe-Dimmer JL, Wood DP, Cooney KA, Seminara D, Ikonen T, Baffoe-Bonnie A, Fredriksson H, Matikainen MP, Tammela TL, Bailey-Wilson J, Schleutker J, Maier C, Herkommer K, Hoegel JJ, Vogel W, Paiss T, Wiklund F, Emanuelsson M, Stenman E, Jonsson BA, Grönberg H, Camp NJ, Farnham J, Cannon-Albright LA, Catalona WJ, Suarez BK, Roehl KA (Nov 2006) Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics., Human genetics, 120 (4), 471-85
 - Kohn MH, Murphy WJ, Ostrander EA, Wayne RK (Nov 2006) Genomics and conservation genetics., Trends in ecology & evolution (Personal edition), 21 (11), 629-37
 - Ostrander EA, Kwon EM, Stanford JL (Oct 2006) Genetic susceptibility to aggressive prostate cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 15 (10), 1761-4
 - Khanna C, Lindblad-Toh K, Vail D, London C, Bergman P, Barber L, Breen M, Kitchell B, McNeil E, Modiano JF, Niemi S, Comstock KE, Ostrander E, Westmoreland S, Withrow S (Sep 2006) The dog as a cancer model., Nature biotechnology, 24 (9), 1065-6
 - Malone KE, Daling JR, Doody DR, Hsu L, Bernstein L, Coates RJ, Marchbanks PA, Simon MS, McDonald JA, Norman SA, Strom BL, Burkman RT, Ursin G, Deapen D, Weiss LK, Folger S, Madeoy JJ, Friedrichsen DM, Suter NM, Humphrey MC, Spirtas R, Ostrander EA (Aug 2006) Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years., Cancer research, 66 (16), 8297-308
 - VonHoldt BM, Ostrander EA (Aug 2006) The singular history of a canine transmissible tumor., Cell, 126 (3), 445-7
 - Chase K, Sargan D, Miller K, Ostrander EA, Lark KG (Jun 2006) Understanding the genetics of autoimmune disease: two loci that regulate late onset Addison's disease in Portuguese Water Dogs., International journal of immunogenetics, 33 (3), 179-84
 - Parker HG, Kruglyak L, Ostrander EA (Mar 2006) Molecular genetics: DNA analysis of a putative dog clone., Nature, 440 (7081), E1-2
 - Kukekova AV, Nelson J, Kuchtey RW, Lowe JK, Johnson JL, Ostrander EA, Aguirre GD, Acland GM (Mar 2006) Linkage mapping of canine rod cone dysplasia type 2 (rcd2) to CFA7, the canine orthologue of human 1q32., Investigative ophthalmology & visual science, 47 (3), 1210-5
 - Stanford JL, McDonnell SK, Friedrichsen DM, Carlson EE, Kolb S, Deutsch K, Janer M, Hood L, Ostrander EA, Schaid DJ (Feb 2006) Prostate cancer and genetic susceptibility: a genome scan incorporating disease aggressiveness., The Prostate, 66 (3), 317-25
 - Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, Ponting CP, Galibert F, Smith DR, DeJong PJ, Kirkness E, Alvarez P, Biagi T, Brockman W, Butler J, Chin CW, Cook A, Cuff J, Daly MJ, DeCaprio D, Gnerre S, Grabherr M, Kellis M, Kleber M, Bardeleben C, Goodstadt L, Heger A, Hitte C, Kim L, Koepfli KP, Parker HG, Pollinger JP, Searle SM, Sutter NB, Thomas R, Webber C, Baldwin J, Abebe A, Abouelleil A, Aftuck L, Ait-Zahra M, Aldredge T, Allen N, An P, Anderson S, Antoine C, Arachchi H, Aslam A, Ayotte L, Bachantsang P, Barry A, Bayul T, Benamara M, Berlin A, Bessette D, Blitshteyn B, Bloom T, Blye J, Boguslavskiy L, Bonnet C, Boukhgalter B, Brown A, Cahill P, Calixte N, Camarata J, Cheshatsang Y, Chu J, Citroen M, Collymore A, Cooke P, Dawoe T, Daza R, Decktor K, DeGray S, Dhargay N, Dooley K, Dorje P, Dorjee K, Dorris L, Duffey N, Dupes A, Egbiremolen O, Elong R, Falk J, Farina A, Faro S, Ferguson D, Ferreira P, Fisher S, FitzGerald M, Foley K, Foley C, Franke A, Friedrich D, Gage D, Garber M, Gearin G, Giannoukos G, Goode T, Goyette A, Graham J, Grandbois E, Gyaltsen K, Hafez N, Hagopian D, Hagos B, Hall J, Healy C, Hegarty R, Honan T, Horn A, Houde N, Hughes L, Hunnicutt L, Husby M, Jester B, Jones C, Kamat A, Kanga B, Kells C, Khazanovich D, Kieu AC, Kisner P, Kumar M, Lance K, Landers T, Lara M, Lee W, Leger JP, Lennon N, Leuper L, LeVine S, Liu J, Liu X, Lokyitsang Y, Lokyitsang T, Lui A, Macdonald J, Major J, Marabella R, Maru K, Matthews C, McDonough S, Mehta T, Meldrim J, Melnikov A, Meneus L, Mihalev A, Mihova T, Miller K, Mittelman R, Mlenga V, Mulrain L, Munson G, Navidi A, Naylor J, Nguyen T, Nguyen N, Nguyen C, Nicol R, Norbu N, Norbu C, Novod N, Nyima T, Olandt P, O'Neill B, O'Neill K, Osman S, Oyono L, Patti C, Perrin D, Phunkhang P, Pierre F, Priest M, Rachupka A, Raghuraman S, Rameau R, Ray V, Raymond C, Rege F, Rise C, Rogers J, Rogov P, Sahalie J, Settipalli S, Sharpe T, Shea T, Sheehan M, Sherpa N, Shi J, Shih D, Sloan J, Smith C, Sparrow T, Stalker J, Stange-Thomann N, Stavropoulos S, Stone C, Stone S, Sykes S, Tchuinga P, Tenzing P, Tesfaye S, Thoulutsang D, Thoulutsang Y, Topham K, Topping I, Tsamla T, Vassiliev H, Venkataraman V, Vo A, Wangchuk T, Wangdi T, Weiand M, Wilkinson J, Wilson A, Yadav S, Yang S, Yang X, Young G, Yu Q, Zainoun J, Zembek L, Zimmer A, Lander ES (Dec 2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog., Nature, 438 (7069), 803-19
 - Thomas R, Scott A, Langford CF, Fosmire SP, Jubala CM, Lorentzen TD, Hitte C, Karlsson EK, Kirkness E, Ostrander EA, Galibert F, Lindblad-Toh K, Modiano JF, Breen M (Dec 2005) Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors., Genome research, 15 (12), 1831-7
 - Chase K, Carrier DR, Adler FR, Ostrander EA, Lark KG (Dec 2005) Interaction between the X chromosome and an autosome regulates size sexual dimorphism in Portuguese Water Dogs., Genome research, 15 (12), 1820-4
 - Ostrander EA, Wayne RK (Dec 2005) The canine genome., Genome research, 15 (12), 1706-16
 - Parker HG, Ostrander EA (Nov 2005) Canine genomics and genetics: running with the pack., PLoS genetics, 1 (5), e58
 - Salinas CA, Austin MA, Ostrander EO, Stanford JL (Sep 2005) Polymorphisms in the androgen receptor and the prostate-specific antigen genes and prostate cancer risk., The Prostate, 65 (1), 58-65
 - Friedrichsen DM, Hawley S, Shu J, Humphrey M, Sabacan L, Iwasaki L, Etzioni R, Ostrander EA, Stanford JL (Sep 2005) IGF-I and IGFBP-3 polymorphisms and risk of prostate cancer., The Prostate, 65 (1), 44-51
 - Hitte C, Madeoy J, Kirkness EF, Priat C, Lorentzen TD, Senger F, Thomas D, Derrien T, Ramirez C, Scott C, Evanno G, Pullar B, Cadieu E, Oza V, Lourgant K, Jaffe DB, Tacher S, Dréano S, Berkova N, André C, Deloukas P, Fraser C, Lindblad-Toh K, Ostrander EA, Galibert F (Aug 2005) Facilitating genome navigation: survey sequencing and dense radiation-hybrid gene mapping., Nature reviews. Genetics, 6 (8), 643-8
 - Ewart-Toland A, Dai Q, Gao YT, Nagase H, Dunlop MG, Farrington SM, Barnetson RA, Anton-Culver H, Peel D, Ziogas A, Lin D, Miao X, Sun T, Ostrander EA, Stanford JL, Langlois M, Chan JM, Yuan J, Harris CC, Bowman ED, Clayman GL, Lippman SM, Lee JJ, Zheng W, Balmain A (Aug 2005) Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types., Carcinogenesis, 26 (8), 1368-73
 - Xu J, Dimitrov L, Chang BL, Adams TS, Turner AR, Meyers DA, Eeles RA, Easton DF, Foulkes WD, Simard J, Giles GG, Hopper JL, Mahle L, Moller P, Bishop T, Evans C, Edwards S, Meitz J, Bullock S, Hope Q, Hsieh CL, Halpern J, Balise RN, Oakley-Girvan I, Whittemore AS, Ewing CM, Gielzak M, Isaacs SD, Walsh PC, Wiley KE, Isaacs WB, Thibodeau SN, McDonnell SK, Cunningham JM, Zarfas KE, Hebbring S, Schaid DJ, Friedrichsen DM, Deutsch K, Kolb S, Badzioch M, Jarvik GP, Janer M, Hood L, Ostrander EA, Stanford JL, Lange EM, Beebe-Dimmer JL, Mohai CE, Cooney KA, Ikonen T, Baffoe-Bonnie A, Fredriksson H, Matikainen MP, Tammela TLj, Bailey-Wilson J, Schleutker J, Maier C, Herkommer K, Hoegel JJ, Vogel W, Paiss T, Wiklund F, Emanuelsson M, Stenman E, Jonsson BA, Gronberg H, Camp NJ, Farnham J, Cannon-Albright LA, Seminara D (Aug 2005) A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics., American journal of human genetics, 77 (2), 219-29
 - Murphy WJ, Larkin DM, Everts-van der Wind A, Bourque G, Tesler G, Auvil L, Beever JE, Chowdhary BP, Galibert F, Gatzke L, Hitte C, Meyers SN, Milan D, Ostrander EA, Pape G, Parker HG, Raudsepp T, Rogatcheva MB, Schook LB, Skow LC, Welge M, Womack JE, O'brien SJ, Pevzner PA, Lewin HA (Jul 2005) Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps., Science (New York, N.Y.), 309 (5734), 613-7
 - Modiano JF, Breen M, Burnett RC, Parker HG, Inusah S, Thomas R, Avery PR, Lindblad-Toh K, Ostrander EA, Cutter GC, Avery AC (Jul 2005) Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk., Cancer research, 65 (13), 5654-61
 - Werner P, Raducha MG, Prociuk U, Ostrander EA, Spielman RS, Kirkness EF, Patterson DF, Henthorn PS (Apr 2005) The keeshond defect in cardiac conotruncal development is oligogenic., Human genetics, 116 (5), 368-77
 - Ostrander G, Ostrander E (Mar 2005) Q & A. [interview], Current biology : CB, 15 (5), R151-2
 - Narla G, Difeo A, Reeves HL, Schaid DJ, Hirshfeld J, Hod E, Katz A, Isaacs WB, Hebbring S, Komiya A, McDonnell SK, Wiley KE, Jacobsen SJ, Isaacs SD, Walsh PC, Zheng SL, Chang BL, Friedrichsen DM, Stanford JL, Ostrander EA, Chinnaiyan AM, Rubin MA, Xu J, Thibodeau SN, Friedman SL, Martignetti JA (Feb 2005) A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk., Cancer research, 65 (4), 1213-22
 - Seddon JM, Parker HG, Ostrander EA, Ellegren H (Feb 2005) SNPs in ecological and conservation studies: a test in the Scandinavian wolf population., Molecular ecology, 14 (2), 503-11
 - Lohi H, Young EJ, Fitzmaurice SN, Rusbridge C, Chan EM, Vervoort M, Turnbull J, Zhao XC, Ianzano L, Paterson AD, Sutter NB, Ostrander EA, André C, Shelton GD, Ackerley CA, Scherer SW, Minassian BA (Jan 2005) Expanded repeat in canine epilepsy., Science (New York, N.Y.), 307 (5706), 81
 - Green SL, Westendorf JM, Jaffe H, Pant HC, Cork LC, Ostrander EA, Vignaux F, Ferrell JE (Jan 2005) Allelic variants of the canine heavy neurofilament (NFH) subunit and extensive phosphorylation in dogs with motor neuron disease., Journal of comparative pathology, 132 (1), 33-50
 - Sutter NB, Ostrander EA (Dec 2004) Dog star rising: the canine genetic system., Nature reviews. Genetics, 5 (12), 900-10
 - Sutter NB, Eberle MA, Parker HG, Pullar BJ, Kirkness EF, Kruglyak L, Ostrander EA (Dec 2004) Extensive and breed-specific linkage disequilibrium in Canis familiaris., Genome research, 14 (12), 2388-96
 - Lee JH, Joo YD, Yim D, Lee R, Ostrander EA, Loretz C, Little MT, Storb R, Kuhr CS (Oct 2004) Molecular cloning and characterization of canine ICOS., Genomics, 84 (4), 730-6
 - Wasser SK, Shedlock AM, Comstock K, Ostrander EA, Mutayoba B, Stephens M (Oct 2004) Assigning African elephant DNA to geographic region of origin: applications to the ivory trade., Proceedings of the National Academy of Sciences of the United States of America, 101 (41), 14847-52
 - Clark LA, Tsai KL, Steiner JM, Williams DA, Guerra T, Ostrander EA, Galibert F, Murphy KE (Sep 2004) Chromosome-specific microsatellite multiplex sets for linkage studies in the domestic dog., Genomics, 84 (3), 550-4
 - Friedrichsen DM, Malone KE, Doody DR, Daling JR, Ostrander EA (2004) Frequency of CHEK2 mutations in a population based, case-control study of breast cancer in young women., Breast cancer research : BCR, 6 (6), R629-35
 - Ostrander EA, Markianos K, Stanford JL (2004) Finding prostate cancer susceptibility genes., Annual review of genomics and human genetics, 5, 151-75
 - Janer M, Friedrichsen DM, Stanford JL, Badzioch MD, Kolb S, Deutsch K, Peters MA, Goode EL, Welti R, DeFrance HB, Iwasaki L, Li S, Hood L, Ostrander EA, Jarvik GP (Dec 2003) Genomic scan of 254 hereditary prostate cancer families., The Prostate, 57 (4), 309-19
 - Lingaas F, Comstock KE, Kirkness EF, Sřrensen A, Aarskaug T, Hitte C, Nickerson ML, Moe L, Schmidt LS, Thomas R, Breen M, Galibert F, Zbar B, Ostrander EA (Dec 2003) A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog., Human molecular genetics, 12 (23), 3043-53
 - Thomas R, Smith KC, Ostrander EA, Galibert F, Breen M (Oct 2003) Chromosome aberrations in canine multicentric lymphomas detected with comparative genomic hybridisation and a panel of single locus probes., British journal of cancer, 89 (8), 1530-7
 - Stanford JL, Sabacan LP, Noonan EA, Iwasaki L, Shu J, Feng Z, Ostrander EA (Sep 2003) Association of HPC2/ELAC2 polymorphisms with risk of prostate cancer in a population-based study., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 12 (9), 876-81
 - Lowe JK, Kukekova AV, Kirkness EF, Langlois MC, Aguirre GD, Acland GM, Ostrander EA (Jul 2003) Linkage mapping of the primary disease locus for collie eye anomaly., Genomics, 82 (1), 86-95
 - Conlon EM, Goode EL, Gibbs M, Stanford JL, Badzioch M, Janer M, Kolb S, Hood L, Ostrander EA, Jarvik GP, Wijsman EM (Jul 2003) Oligogenic segregation analysis of hereditary prostate cancer pedigrees: evidence for multiple loci affecting age at onset., International journal of cancer. Journal international du cancer, 105 (5), 630-5
 - Lowe JK, Guyon R, Cox ML, Mitchell DC, Lonkar AL, Lingaas F, André C, Galibert F, Ostrander EA, Murphy KE (Jul 2003) Radiation hybrid mapping of the canine type I and type IV collagen gene subfamilies., Functional & integrative genomics, 3 (3), 112-6
 - Guyon R, Lorentzen TD, Hitte C, Kim L, Cadieu E, Parker HG, Quignon P, Lowe JK, Renier C, Gelfenbeyn B, Vignaux F, DeFrance HB, Gloux S, Mahairas GG, André C, Galibert F, Ostrander EA (Apr 2003) A 1-Mb resolution radiation hybrid map of the canine genome., Proceedings of the National Academy of Sciences of the United States of America, 100 (9), 5296-301
 - Acland GM, Ostrander EA (Mar 2003) The dog that came in from the cold., Heredity, 90 (3), 201-2
 - Suter NM, Malone KE, Daling JR, Doody DR, Ostrander EA (Feb 2003) Androgen receptor (CAG)n and (GGC)n polymorphisms and breast cancer risk in a population-based case-control study of young women., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 12 (2), 127-35
 - Fleming MA, Potter JD, Ramirez CJ, Ostrander GK, Ostrander EA (Feb 2003) Understanding missense mutations in the BRCA1 gene: an evolutionary approach., Proceedings of the National Academy of Sciences of the United States of America, 100 (3), 1151-6
 - Comstock KE, Georgiadis N, Pecon-Slattery J, Roca AL, Ostrander EA, O'Brien SJ, Wasser SK (Dec 2002) Patterns of molecular genetic variation among African elephant populations., Molecular ecology, 11 (12), 2489-98
 - Zhi X, Szabo C, Chopin S, Suter N, Wang QS, Ostrander EA, Sinilnikova OM, Lenoir GM, Goldgar D, Shi YR (Dec 2002) BRCA1 and BRCA2 sequence variants in Chinese breast cancer families., Human mutation, 20 (6), 474
 - Sidjanin DJ, Lowe JK, McElwee JL, Milne BS, Phippen TM, Sargan DR, Aguirre GD, Acland GM, Ostrander EA, Canine CNGB3 mutations establish cone degeneration as orthologous to the human achromatopsia locus ACHM3, Human Molecular Genetics, 11(16), 1823-33, Aug 2002
 - Chase K, Carrier DR, Adler FR, Jarvik T, Ostrander EA, Lorentzen TD, Lark KG (Jul 2002) Genetic basis for systems of skeletal quantitative traits: principal component analysis of the canid skeleton., Proceedings of the National Academy of Sciences of the United States of America, 99 (15), 9930-5
 - Sidjanin DJ, Zangerl B, Johnson JL, Xue F, Mellersh C, Ostrander EA, Acland G, Aguirre GD, Cloning of the canine delta tubulin cDNA (TUBD) and mapping to CFA9, Animal Genetics, 33(2), 161-2, April 2002
 - Stanford JL, Noonan EA, Iwasaki L, Kolb S, Chadwick RB, Feng Z, Ostrander EA, A Polymorphism in the CYP17 Gene and Risk of Prostate Cancer, 11(3), 243-7, March 2002
 - Akhmedov NB, Baldwin VJ, Zangerl B, Kijas JW, Hunter L, Minoofar KD, Mellersh C, Ostrander EA, Acland GM, Farber DB, Aguirre GD, Cloning and characterization of the canine photoreceptor specific cone-rod homeobox (CRX) gene and evaluation as a candidate for early onset photoreceptor diseases in the dog, Molecular Vision [electronic Resource], 8, 79-84, March 2002
 - Stanford JL, Noonan EA, Iwasaki L, Kolb S, Chadwick RB, Feng Z, Ostrander EA (Mar 2002) A polymorphism in the CYP17 gene and risk of prostate cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 11 (3), 243-7
 - Thompson D, Szabo CI, Mangion J, Oldenburg RA, Odefrey F, Seal S, Barfoot R, Kroeze-Jansema K, Teare D, Rahman N, Renard H, Mann G, Hopper JL, Buys SS, Andrulis IL, Senie R, Daly MB, West D, Ostrander EA, Offit K, Peretz T, Osorio A, Benitez J, Nathanson KL, Sinilnikova OM, Olŕh E, Bignon YJ, Ruiz P, Badzioch MD, Vasen HF, Futreal AP, Phelan CM, Narod SA, Lynch HT, Ponder BA, Eeles RA, Meijers-Heijboer H, Stoppa-Lyonnet D, Couch FJ, Eccles DM, Evans DG, Chang-Claude J, Lenoir G, Weber BL, Devilee P, Easton DF, Goldgar DE, Stratton MR (Jan 2002) Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium., Proceedings of the National Academy of Sciences of the United States of America, 99 (2), 827-31
 - Zhang Q, Acland GM, Zangerl B, Johnson JL, Mao Z, Zeiss CJ, Ostrander EA, Aguirre GD, Fine mapping of canine XLPRA establishes homology of the human and canine RP3 intervals, Investigative Ophthalmology and Visual Science, 42(11), 2466-71, October 2001
 - Peters MA, Janer M, Kolb S, Jarvik GP, Ostrander EA, Stanford JL, Germline mutations in the p73 gene do not predispose to familial prostate-brain cancer, Prostate, 48(4), 292-6, 2001
 - Goode EL, Stanford JL, Peters MA, Janer M, Gibbs M, Kolb S, Badzioch MD, Hood L, Ostrander EA, Jarvik GP, Clinical characteristics of prostate cancer in an analysis of linkage to four putative susceptibility loci, Clinical Cancer Research, 7(9), 2739-49, September 2001
 - Miller AB, Lowe JK, Ostrander EA, Galibert F, Murphy KE, Cloning, sequence analysis and radiation hybrid mapping of a mammalian KRT2p gene, Functional & Integrative Genomics, 1(5), 305-11, September 2001
 - Miller AB, Lowe JK, Ostrander EA, Galibert F, Murphy KE (Sep 2001) Cloning, sequence analysis and radiation hybrid mapping of a mammalian KRT2p gene., Functional & integrative genomics, 1 (5), 305-11
 - Miller EA, Stanford JL, Hsu L, Noonan E, Ostrander EA, Polymorphic repeats in the androgen receptor gene in high-risk sibships, Prostate, 48(3), 200-5, 2001
 - Teraoka SN, Malone KE, Doody DR, Suter NM, Ostrander EA, Daling JR, Concannon P, Increased frequency of ATM mutations in breast carcinoma patients with early onset disease and positive family history, Cancer, 92(3), 479-87, 2001
 - Li R, Faraco JH, Lin L, Lin X, Hinton L, Rogers W, Lowe JK, Ostrander EA, Mignot E, Physical and radiation hybrid mapping of canine chromosome 12, in a region corresponding to human chromosome 6p12-q12, Genomics, 73(3), 299-315, 2001
 - Peters ME, Ostrander EA, Prostate cancer: simplicity to complexity, Nature Genetics, 27(2), 134-5, February 2001
 - Richman M, Mellersh CS, Andre C, Galibert F, Ostrander EA, Characterization of a minimal screening set of 172 microsatellite markers for genome-wide screens of the canine genome, Journal of Biochemical and Biophysical Methods, 47(1-2), 137-49, 2001
 - Credille KM, Venta PJ, Breen M, Lowe JK, Murphy KE, Ostrander EA, Galibert F, Dunstan RW, DNA sequence and physical mapping of the canine transglutaminase 1 gene, Cytogenetics and Cell Genetics, 93(1-2), 73-6, 2001
 - Peters MA, Jarvik GP, Janer M, Chakrabarti L, Kolb S, Goode EL, Gibbs M, DuBois CC, Schuster EF, Hood L, Ostrander EA, Stanford JL, Genetic linkage analysis of prostate cancer families to Xq27-28, Human Heredity, 51(1-2), 107-13, 2001
 - Eng, C., Brody, L.C., Wagner, T.M., Devilee, P., Vijg, J., Szabo, C., Tavtigian, S.V., Nathanson, K.L., Ostrander, E.A., Frank. T. S., Interpreting epidemiological research: Blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1, Journal of Medical Genetics, 38, 824-833, 2001
- Parker H.G., Yuhua X., Mellersh C.S., Khan S., Shibuya H., Johnson G.S., Ostrander E.A., Meiotic linkage mapping of 52 genes onto the canine map does not identify significant levels of microrearrangement, Mammalian Genome, 12, 713-718, 2001
- Nelson P.S., Stanford J.L., Ostrander E.A., Prostate cancer research in the post-genome era, Epidemiologic Reviews, 23, 187-190, 2001
- Sidjanin D.J., Xue F., McElwee J., Johnson J.L., Holmgren C., Mellersh C., Ostrander E., Acland G., Aguirre G.D., Cloning of canine gamma tubulin (TUBG1) cDNA and mapping of CFA9, Animal Genetics, 32, 328-329, 2001
- Stanford J.L., Ostrander E.A., Familial prostate cancer, Epidemiologic Reviews, 19-23, 2001
- Breen M, Jouquand S, Renier C, Mellersh CS, Hitte C, Holmes NG, Chéron A, Suter N, Vignaux F, Bristow AE, Priat C, McCann E, André C, Boundy S, Gitsham P, Thomas R, Bridge WL, Spriggs HF, Ryder EJ, Curson A, Sampson J, Ostrander EA, Binns MM Galibert F, Chromosome-specific single locus FISH probes allow anchorage of a 1,800 marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes, Genome Research, 11, 1784-1795, 2001
- Ostrander EA, Stanford JL, Genetics of prostate cancer: too many loci, too few genes, American Journal of Human Genetics, 67(6), 1367-75, December 2000
 - Ostrander EA, Kruglyak L, Unleashing the canine genome, Genome Research, 10(9), 1271-4, September 2000
 - Gibbs M, Stanford JL, Jarvik GP, Janer M, Badzioch M, Peters MA, Goode EL, Kolb S, Chakrabarti L, Shook M, Basom R, Ostrander EA, Hood L, A genomic scan of families with prostate cancer identifies multiple regions of interest, American Journal of Human Genetics, 67(1), 100-9, July 2000
 - Comstock KE, Wasser SK, Ostrander EA, Polymorphic microsatellite DNA loci identified in the African elephant (Loxodonta africana), Molecular Ecology, 9(7), 1004-6, July 2000
 - Jonasdottir TJ, Mellersh CS, Moe L, Heggebo R, Gamlem H, Ostrander EA, Lingaas F, Genetic mapping of a naturally occurring hereditary renal cancer syndrome in dogs, Proceedings of the National Academy of Sciences (USA), 97(8), 4132-7, April 2000
 - Jonasdottir TJ, Mellersh CS, Moe L, Vignaux F, Ostrander EA, Lingaas F, Chromosomal assignment of canine TSC2, PKD1 and CLN3 genes by radiation hybrid- and linkage analyses, Animal Genetics, 31(2), 123-6, April 2000
 - Ostrander EA, Galibert F, Patterson DF, Canine genetics comes of age, Trends in Genetics, 16(3), 117-24, March 2000
 - Goode EL, Stanford JL, Chakrabarti L, Gibbs M, Kolb S, McIndoe RA, Buckley VA, Schuster EF, Neal CL, Miller EL, Brandzel S, Hood L, Ostrander EA, Jarvik GP, Linkage analysis of 150 high-risk prostate cancer families at 1q24-25, Genetic Epidemiology, 18(3), 251-75, March 2000
 - Malone KE, Daling JR, Neal C, Suter NM, O'Brien C, Cushing-Haugen K, Jonasdottir TJ, Thompson JD, Ostrander EA, Frequency of BRCA1/BRCA2 mutations in a population-based sample of young breast carcinoma cases, Cancer, 88(6), 1393-402, March 2000
 - Mellersh CS, Hitte C, Richman M, Vignaux F, Priat C, Jouquand S, Werner P, Andre C, DeRose S, Patterson DF, Ostrander EA, Galibert F, An integrated linkage-radiation hybrid map of the canine genome, Mammalian Genome, 11(2), 120-30, February 2000
 - Xu J., and the International Consortium for Prostate Cancer Genetics, Combined analysis of hereditary prostate cancer linkage to 1q24-25: Results from 772 hereditary prostate cancer families from the International Consortium for Prostate Cancer Genetics, American Journal of Human Genetics, 66, 945-957, 2000
- Ostrander EA, Kruglyak L, Unleashing the canine genome, Genome Research, 10, 1271-1274, 2000
- Ostrander EA, Giniger E, Let sleeping dogs lie?, Nature Genetics, 23(1), 3-4, September 1999
 - Wang W, Zhang Q, Acland GM, Mellersh C, Ostrander EA, Ray K, Aguirre GD, Molecular characterization and mapping of canine cGMP-phosphodiesterase delta subunit (PDE6D), Gene, 236(2), 325-32, 1999
 - Werner P, Mellersh CS, Raducha MG, DeRose S, Acland GM, Prociuk U, Wiegand N, Aguirre GD, Henthorn PS, Patterson DF, Ostrander EA, Anchoring of canine linkage groups with chromosome-specific markers, Mammalian Genome, 10(8), 814-23, August 1999
 - Acland GM, Ray K, Mellersh CS, Langston AA, Rine J, Ostrander EA, Aguirre GD, A novel retinal degeneration locus identified by linkage and comparative mapping of canine early retinal degeneration, Genomics, 59(2), 134-42, 1999
 - Gu W, Ray K, Pearce-Kelling S, Baldwin VJ, Langston AA, Ray J, Ostrander EA, Acland GM, Aguirre GD, Evaluation of the APOH gene as a positional candidate for prcd in dogs, Investigative Ophthalmology and Visual Science, 40(6), 1229-37, May 1999
 - Li R, Mignot E, Faraco J, Kadotani H, Cantanese J, Zhao B, Lin X, Hinton L, Ostrander EA, Patterson DF, de Jong PJ, Construction and characterization of an eightfold redundant dog genomic bacterial artificial chromosome library, Genomics, 58(1), 9-17, May 1999
 - Gibbs M, Chakrabarti L, Stanford JL, Goode EL, Kolb S, Schuster EF, Buckley VA, Shook M, Hood L, Jarvik GP, Ostrander EA, Analysis of chromosome 1q42.2-43 in 152 families with high risk of prostate cancer, American Journal of Human Genetics, 64(4), 1087-95, April 1999
 - Gibbs M, Stanford JL, McIndoe RA, Jarvik GP, Kolb S, Goode EL, Chakrabarti L, Schuster EF, Buckley VA, Miller EL, Brandzel S, Li S, Hood L, Ostrander EA, Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36, American Journal of Human Genetics, 64(3), 776-87, March 1999
 - Wayne RK, Ostrander EA, Origin, genetic diversity, and genome structure of the domestic dog, Bioessays, 21(3), 247-57, March 1999
 - Neff MW, Broman KW, Mellersh CS, Ray K, Acland GM, Aguirre GD, Ziegle JS, Ostrander EA, Rine J, A second-generation genetic linkage map of the domestic dog, Canis familiaris, Genetics, 151(2), 803-20, February 1999
 - Langston AA, Mellersh CS, Wiegand NA, Acland GM, Ray K, Aguirre GD, Ostrander EA, Toward a framework linkage map of the canine genome, Journal of Heredity, 90(1), 7-14, 1999
 - Fleming M.A., Ostrander E.A., Cook J.A., Microsatellite markers for American mink (Mustela vison) and ermine (Mustela erminea), Molecular Ecology, 8, 1352-1354, 1999
- Jarvik GP, Stanford JL, Goode EL, McIndoe R, Kolb S, Gibbs M, Hood L, Ostrander EA, Confirmation of prostate cancer susceptibility genes using high-risk families, Journal of the National Cancer Institute. Monographs, 81-7, 1999
 - Blazej RG, Mellersh CS, Cork LC, Ostrander EA, Hereditary canine spinal muscular atrophy is phenotypically similar but molecularly distinct from human spinal muscular atrophy, Journal of Heredity, 89(6), 531-7, 1998
 - Gu W, Acland GM, Langston AA, Ostrander EA, Aguirre GD, Ray K, Identification of a RAPD marker linked to progressive rod-cone degeneration in dogs, Mammalian Genome, 9(9), 740-4, September 1998
 - Graumann MB, DeRose SA, Ostrander EA, Storb R, Polymorphism analysis of four canine MHC class I genes, Tissue Antigens, 51(4 Pt 1), 374-81, April 1998
 - Acland GM, Ray K, Mellersh CS, Gu W, Langston AA, Rine J, Ostrander EA, Aguirre GD, Linkage analysis and comparative mapping of canine progressive rod-cone degeneration (prcd) establishes potential locus homology with retinitis pigmentosa (RP17) in humans, Proceedings of the National Academy of Sciences (USA), 95(6), 3048-53, March 1998
 - Malone KE, Daling JR, Thompson JD, O'Brien CA, Francisco LV, Ostrander EA, BRCA1 mutations and breast cancer in the general population: analyses in women before age 35 years and in women before age 45 years with first-degree family history, Jama, 279(12), 922-9, March 1998
 - Langston AA, Mellersh CS, Neal CL, Ray K, Acland GM, Gibbs M, Aguirre GD, Fournier RE, Ostrander EA, Construction of a panel of canine-rodent hybrid cell lines for use in partitioning of the canine genome, Genomics, 46(3), 317-25, December 1997
 - Mellersh CS, Langston AA, Acland GM, Fleming MA, Ray K, Wiegand NA, Francisco LV, Gibbs M, Aguirre GD, Ostrander EA, A linkage map of the canine genome, Genomics, 46(3), 326-36, December 1997
 - Ostrander EA, Giniger E, Semper fidelis: what man's best friend can teach us about human biology and disease, American Journal of Human Genetics, 61(3), 475-80, September 1997
 - McIndoe RA, Stanford JL, Gibbs M, Jarvik GP, Brandzel S, Neal CL, Li S, Gammack JT, Gay AA, Goode EL, Hood L, Ostrander EA, Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25, American Journal of Human Genetics, 61(2), 347-53, August 1997
 - Stanford JL, Just JJ, Gibbs M, Wicklund KG, Neal CL, Blumenstein BA, Ostrander EA, Polymorphic repeats in the androgen receptor gene: molecular markers of prostate cancer risk, Cancer Research, 57(6), 1194-8, March 1997
 - Langston AA, Ostrander EA, Hereditary ovarian cancer, Current Opinion in Obstetrics and Gynecology, 9(1), 3-7, February 1997
 - Mellersh CS, Ostrander EA, The canine genome, Advances in Veterinary Medicine, 40, 191-216, 1997
 - Neuhausen SL, Ostrander EA, Mutation testing of early-onset breast cancer genes BRCA1 and BRCA2, Genetic Testing, 1(2), 75-83, 1997
 - Wagner JL, Burnett RC, DeRose SA, Francisco LV, Storb R, Ostrander EA, Histocompatibility testing of dog families with highly polymorphic microsatellite markers, Transplantation, 62(6), 876-7, 1996
 - Szabo CI, Wagner LA, Francisco LV, Roach JC, Argonza R, King MC, Ostrander EA, Human, canine and murine BRCA1 genes: sequence comparison among species, Human Molecular Genetics, 5(9), 1289-98, September 1996
 - Francisco LV, Langston AA, Mellersh CS, Neal CL, Ostrander EA, A class of highly polymorphic tetranucleotide repeats for canine genetic mapping, Mammalian Genome, 7(5), 359-62, May 1996
 - Langston AA, Stanford JL, Wicklund KG, Thompson JD, Blazej RG, Ostrander EA, Germ-line BRCA1 mutations in selected men with prostate cancer, American Journal of Human Genetics, 58(4), 881-4, April 1996
 - Langston AA, Malone KE, Thompson JD, Daling JR, Ostrander EA, BRCA1 mutations in a population-based sample of young women with breast cancer, New England Journal of Medicine, 334(3), 137-42, January 1996
 - Wagner LA, Kiem HP, McSweeney P, Schuening FG, Storb R, Ostrander EA, Development of a clonality assay for canine hematopoietic stem cells, Blood, 86(8), 3265-7, October 1995
 - Burnett RC, Francisco LV, DeRose SA, Storb R, Ostrander EA, Identification and characterization of a highly polymorphic microsatellite marker within the canine MHC class I region, Mammalian Genome, 6(9), 684-5, September 1995
 - Ostrander EA, Mapa FA, Yee M, Rine J, One hundred and one new simple sequence repeat-based markers for the canine genome, Mammalian Genome, 6(3), 192-5, March 1995
 - Gottelli D, Sillero-Zubiri C, Applebaum GD, Roy MS, Girman DJ, Garcia-Moreno J, Ostrander EA, Wayne RK, Molecular genetics of the most endangered canid: the Ethiopian wolf Canis simensis, Molecular Ecology, 3(4), 301-12, August 1994
 - Roy MS, Geffen E, Smith D, Ostrander EA, Wayne RK, Patterns of differentiation and hybridization in North American wolflike canids, revealed by analysis of microsatellite loci, Molecular Biology and Evolution, 11(4), 553-70, July 1994
 - Lowry SR, Wilson K, Blazej R, Chiu J, Rine J, Ostrander EA, Identification, characterization, and physical mapping of 14 polymorphic simple sequence repeat markers on human chromosome 21, Genomics, 21(3), 633-7, June 1994
 - Lishanski A, Ostrander EA, Rine J, Mutation detection by mismatch binding protein, MutS, in amplified DNA: application to the cystic fibrosis gene, Proceedings of the National Academy of Sciences (USA), 91(7), 2674-8, 1994
 - Ostrander EA, Rine J, Sack GH Jr, Cork LC, What is the role of molecular genetics in modern veterinary practice?, Journal of the American Veterinary Medical Association, 203(9), 1259-62, November 1993
 - Ostrander EA, Sprague GF Jr, Rine J, Identification and characterization of dinucleotide repeat (CA)n markers for genetic mapping in dog, Genomics, 16(1), 207-13, April 1993
 - Dunaway M, Ostrander EA, Local domains of supercoiling activate a eukaryotic promoter in vivo, Nature, 361(6414), 746-8, February 1993
 - Ostrander EA, Jong PM, Rine J, Duyk G, Construction of small-insert genomic DNA libraries highly enriched for microsatellite repeat sequences, Proceedings of the National Academy of Sciences (USA), 89(8), 3419-23, April 1992
 - Ostrander EA, Benedetti P, Wang JC, Template supercoiling by a chimera of yeast GAL4 protein and phage T7 RNA polymerase, Science, 249(4974), 1261-5, September 1990
 - Ostrander EA, Kurkinen NA, Hallick LM, DNA structural alterations in the SV40 enhancer region are retained in vivo, Virology, 165(1), 274-7, July 1988
 - Ostrander EA, Karty RA, Hallick LM, High resolution psoralen mapping reveals an altered DNA helical structure in the SV40 regulatory region, Nucleic Acids Research, 16(1), 213-27, 1988
 - Ostrander E.A., Maslen C.L., Hallick L.M., Recovery of critical DNA samples from laboratory bench paper, Focus, 9, 9, 1987
- Ostrander EA, Robinson GW, Isaacs ST, Tessman J, Hallick LM, The site-specific inhibition of Bgl I cleavage by psoralen photoadducts, Photochemistry and Photobiology, 44(1), 21-9, July 1986
 - Sargan DR, Aguirre-Hernandez J, Galibert F, Ostrander EA, An extended microsatellite set for linkage mapping in the domestic dog., The Journal of heredity, 98 (3), 221-31
 - Hitte C, Lorentzen TD, Guyon R, Kim L, Cadieu E, Parker HG, Quignon P, Lowe JK, Gelfenbeyn B, Andre C, Ostrander EA, Galibert F, Comparison of MultiMap and TSP/CONCORDE for constructing radiation hybrid maps., The Journal of heredity, 94 (1), 9-13
 - Gordon D, Corwin MB, Mellersh CS, Ostrander EA, Ott J, Establishing appropriate genome-wide significance levels for canine linkage analyses., The Journal of heredity, 94 (1), 1-7
 - Wisely SM, Buskirk SW, Fleming MA, McDonald DB, Ostrander EA, Genetic diversity and fitness in black-footed ferrets before and during a bottleneck., The Journal of heredity, 93 (4), 231-7

Profile DetailsIndividual Expertise profile of Elaine A. Ostrander, Copyright Elaine A. Ostrander. © COS Expertise TM, 2008, ProQuest LLC All rights reserved. |